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Mitosis, Mieosis, and DNA

Total questions: 25

Worksheet time: 13mins

Name
Class
Date
1.

Chargaff's rule states the following for DNA:

a)

A=T

G=C

b)

G=T

A=C

c)

A=U

G=C

d)

U=T

A=C

2.

If the DNA sequence is A-T-C-T-A-T in one polynucleotide chain, what would the complimentary chain read?

a)

T-A-G-A-T-A

b)

U-A-G-A-U-A

c)

A-T-C-T-A-T

d)

T-A-T-U-C-A

3.

Watson and Crick are credited with the discovery and description of the DNA

a)

deoxyribose sugar.

b)

phosphate group.

c)

double helix.

d)

hydrogen bonds.

4.

  All of the following occur during DNA replication EXCEPT

a)

separation of parental DNA strands.

b)

synthesis of totally new double-stranded DNA molecules.

c)

use of DNA polymerase enzymes.

d)

use of parental DNA as a template.

5.

Which of the following ENZYME is NOT involved in the DNA replication process?

a)

DNA helicase

b)

DNA ligase

c)

DNA polymerase

d)

DNA replicase

6.

What is the name of the enzyme that removes the RNA primer from the DNA strand during DNA Replication?

a)

DNA polymerase I

b)

DNA polymerase III

c)

DNA ligase

d)

DNA helicase

7.

A DNA sequence of 5'-A-C-G-T-A-C-G-T-3' is altered to 5'-A-C-G-C-A-C-G-T-3'. This could happen as a result of a

a)

nucleotide substitution mutation

b)

insertion mutation

c)

deletion mutation

d)

inversion.

8.

The elongation of the leading strand during DNA synthesis

a)

occurs in the 3' → 5' direction.

b)

depends on the action of DNA polymerase.

c)

progresses away from the replication fork.

d)

produces Okazaki fragments.

9.

cell division produces two daughter cells that are genetically identical. This type of cell division is important for all of the following functions EXCEPT ________.

a)

growth of a multicellular organism

b)

cell replacement

c)

production of sperm and egg

d)

asexual reproduction

10.

Which of the following help(s) to hold the DNA strands apart while they are being replicated?

a)

primase

b)

double-strand binding proteins

c)

single-strand binding proteins

d)

DNA polymerase

11.

  The CORRECT sequence of stages of mitosis is

a)

prophase, metaphase, anaphase, telophase

b)

telophase, prophase, anaphase, metaphase

c)

anaphase, interphase, prophase, metaphase, telophase

d)

interphase, prophase, metaphase, anaphase, telophase

12.

  Crossing over occurs during

a)

prophase II

b)

metaphase I

c)

prophase I

d)

anaphase I

13.

Genetic variation is accomplished by all but one of the following. Choose the exception.

a)

the events of meiosis I

b)

crossing over

c)

independent assortment

d)

the events of meiosis II

14.

  What chromosomes belong to a normal human male?

a)

23 autosomes and two Y chromosomes

b)

44 autosomes and two Y chromosomes

c)

44 autosomes, one X chromosome, and one Y chromosome

d)

46 autosomes, one X chromosome, and one Y chromosome

15.

Which of the following events occurs in meiosis but not in mitosis?

a)

chromosome replication

b)

condensation of chromatin

c)

production of daughter cells

d)

synapsis of chromosomes

16.

Which structures is found in a pair of homologous chromosomes?

a)

four sister chromatids

b)

two sister chromatids that have synapsed

c)

two single-stranded chromosomes that have synapsed

d)

four unique chromosomes

17.

  For a chemotherapeutic drug to be useful for treating cancer cells, which of the following is most desirable?

a)

It is safe enough to limit all apoptosis.

b)

It targets only rapidly dividing cells.

c)

It only attacks cells that are density dependent.

d)

It does not affect metabolically active cells.

18.

During mitosis in animal cells, at which phase do centrioles begin to move apart?

a)

anaphase

b)

metaphase

c)

prophase

d)

prometaphase

19.

Which is checkpoint in the cell cycle is typically the most important?

a)

G1

b)

S

c)

M

d)

G2

20.

The set of all Genes that are found on a molecule of DNA is know as a species

a)

protein

b)

family tree

c)

heredity

d)

genome

21.

Which of the following best describes the function of topoisomerase during DNA replication?

a)

Synthesizes RNA primers

b)

Unwinds the DNA double helix

c)

Joins Okazaki fragments

d)

Relieves tension ahead of the replication fork

22.

Which enzyme is responsible for unwinding the DNA double helix during replication?

a)

DNA polymerase

b)

DNA ligase

c)

DNA helicase

d)

Primase

23.

During which phase of mitosis do chromosomes align at the center of the cell?

a)

Prophase

b)

Telophase

c)

Metaphase

d)

Anaphase

24.

Which of the following processes results in the formation of gametes with half the number of chromosomes as the parent cell?

a)

Budding

b)

Binary fission

c)

Meiosis

d)

Mitosis

25.

During DNA replication, which enzyme is responsible for joining Okazaki fragments on the lagging strand?

a)

Primase

b)

DNA ligase

c)

Topoisomerase

d)

DNA helicase