WorksheetsImmunology Quiz 2
Total questions: 50
Worksheet time: 25mins
Any substance that causes your immune system to produce antibodies against it. Maybe a foreign substance from the environment, such as chemicals, bacteria, viruses, or pollen.
Vaccine
Toxin
Antibody
Antigen
Also known as an immunoglobulin (Ig), this is a large, Y-shaped protein produced by plasma cells that are used by the immune system to identify and neutralize pathogens such as bacteria and viruses.
B cells
T cells
Antibody
Antigen
An immunity that is the type of host defense that is always present in healthy individuals. It is always ready and prepared to block the entry
Innate immunity
Adaptive immunity
Humoral Immunity
Cell-mediated immunity
An immunity that is a type of host defense that always require activation and stimulation of the host tissue by pathogens or harmful materials
Innate immunity
Adaptive immunity
Native immunity
Humoral Immunity
An immune response that is mediated by secreted antibodies produced in the cells of the B lymphocyte lineages (B cells).
Self Immunity
Innate immunity
Humoral Immunity
Cell-mediated immunity
An immune response that involves the activation of T lymphocytes (Cytotoxic T and Helper T) and the release of various cytokines in response to an antigen
Cellular immunity
Humoral Immunity
Self Immunity
Natural Immunity
Ensures that immune response are precisely targeted to microbial pathogens
Specificity
Avidity
Diversity
Memory
A person who took a drug that destroys the thymus would most likely ___.
lack class I MHC molecules on cell surfaces
be unable to genetically rearrange antigen receptors
be unable to differentiate and mature T cells
lack innate immunity
The activation of helper T cells is likely ________.
when an antigen is displayed by a dendritic cell
when a cytotoxic T cell releases cytokines
when natural killer cells come in contact with a tumor cell
in the bone marrow during the self-tolerance test
Which statement best describes the difference in responses of effector B cells (or plasma cells) and cytotoxic T cells?
Effector B cells secrete antibodies that are specific for a certain pathogen; cytotoxic T cells kill pathogen-infected host cells.
Effector B cells kill pathogens directly; cytotoxic T cells kill host cells.
Effector B cells confer active immunity; cytotoxic T cells confer passive immunity.
Effector B cells carry out the cell-mediated response; cytotoxic T cells carry out the humoral response.
You and a friend were in line for a movie when you noticed the woman in front of you sneezing and coughing. Both of you were equally exposed to the woman's virus, but over the next few days, only your friend acquired flu-like symptoms and was ill for almost a week before recovering. Which one of the following is a logical explanation for this?
Your friend had an autoimmune disorder.
Your friend had allergies.
Your friend had antibodies to that virus.
You had an adaptive immunity to that virus.
Which of the following is a TCR co receptor?
alpha/beta
alpha/beta + gamma/epsilon, zetax2, delta/epsilon + CD4/CD8
alpha/beta + gamma/epsilon, zetax2, delta/epsilon
CD4/CD8
Which of the following is NOT a possible scenario when a pathogen has entered into blood stream?
Antigen-Macrophage>Tcell>Bcell>sIg>complement system> inflammation
Antigen-Tcell>Bcell> sIg>complement system> inflammation
Antigen-Bcell>Tcell>Bcell> sIg>complement system> inflammation
Antigen-Neutrophils>phagocytosis>Macrophage>>Tcell>Bcell>sIg>complement system> inflammation
Antigen contact points in the Variable region are referred to as
Complementary regions
Complementary determining regions
Complementarity determining regions
Epitopes
CD4 markers are found in which cell
helper
regulatory
cytotoxic
memory
Cells that physically and chemically attack antigens
Helper T cells
Memory T cells
cytotoxic T cells
Regulatory T cells
Cells that activate T and B cell responses
Helper T cells
Memory T cells
cytotoxic T cells
Regulatory T cells
Subclasses of T cells that control immune response
Helper T cells
Memory T cells
cytotoxic T cells
Regulatory T cells
Cells that retain memory of previous antigens and respond by cloning themselves
Helper T cells
Memory T cells
cytotoxic T cells
Regulatory T cells
Immunity provided by cytotoxic T cells; Defends against abnormal cells and pathogens inside cells
cell mediated immunity
antibody mediated immunity aka humoral
Type of immunity provided by B cells; Defends against antigens and pathogens in body fluids
cell-mediated immunity
antibody-mediated immunity aka humoral
Class II MHC proteins are found only where?
membranes of non nucleated cells
membranes of antigen-presenting cells
membranes of nucleated cells
membranes of lymphocytes
What are the type of T Cell CD Markers?
CD4
CD12
CD8
CD3
CD8 T cells can produce which cells
memory
regulatory
cytotoxic
helper
Cell that perform immune surveillance
helper cells
memory
cytotoxic
regulatory
Cytotoxic T cells release perforins and cytokines and trigger
apoptosis
apostosis
Produced simultaneously with cytotoxic T cells
Memory
Regulatory
Helper
Activation of CD4 T cells produces
helper
regulatory
memory
cytotoxic
Which is not a function of an interleukin
increases T cell sensitivity
Enhancing innate immunity
stimulating B cell activity
enhancing adaptive immunity
suppressing immune system and shortening immune response
Largest and most diverse class of antibodies
IgM
IgG
IgD
IgA
Antibody stimulates cell to accelerate inflammation
IgE
IgM
IgA
igG
Binding of this immunoglobulin plays a role in sensitization of the B cell
IgM
IgA
IgG
IgD
First antibody to be secreted after an antigen is encountered
IgG
IgD
IgA
IgM
Found primarily in glandular secretions and attacks pathogens before they gain access to internal tissues
IgG
IgM
IgA
IgD
What shape describes an antibody?
Z shaped
Y shaped
W shaped
T shaped
The immune response that defends against antigens dissolved in body fluids is called:
inflammatory response
interferons
humoral response
cell mediated response
Which of the following plays the biggest role in humoral immunity?
mast cells
cytotoxic T cells
B cells
platelets
Which of the following plays the biggest role in cell mediated immunity?
mast cells
cytotoxic T cells
B cells
platelets
A CD4+ helper T cell is involved in which of the following immune responses?
cell mediated immunity
humoral immunity
both
neither
Which type of antigen-presenting molecule is found only on macrophages, dendritic cells, and B cells?
MHC class 1
MHC class 2
T-cell receptor
B-cell receptor
MHC II molecules present
processed foreign antigens from proteasomes.
antibodies.
T cell receptors.
processed foreign antigens from phagolysosomes
CD4 T cells are generally restricted by
CD-1
MHC class 1
MHC class II
β2 microglobulin
A single antigen molecule may be composed of many individual
MHC class 2
epitopes
RIG-like receptors
T-cell receptors
Microfold cells (or M cells) are found in the gut-associated lymphoid tissue (GALT) of the Peyer's patches in the small intestine, and in the mucosa-associated lymphoid tissue (MALT) of other parts of the gastrointestinal tract
True
False
Immunoagglutination tests goal :
detect Ag-Ab complexes
identify an Ag, in this case Ag1 is known and Ag2 is unknown
determine if there is a kinship between two Ag
How do cytotoxic T cells destroy infected/cancerous cells?
Release free radicals onto the cell
Insert pore like structures called Perforins into their membranes
Engulf the cell by phagocytosis
Release antibodies which cause the cell to burst.
T cells require passage through thymus to complete their maturation
True
False
The lymphatic cells reach the lymp nodes via
High endothelial venules
arterioles
MHC II molecules present
processed foreign antigens from proteasomes.
antibodies.
T cell receptors.
processed foreign antigens from phagolysosomes
Which type of antigen-presenting molecule is found on all nucleated cells?
MHC class 1
MHC class 2
B cell receptor
antibodies
