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Immunology Quiz 2

Total questions: 50

Worksheet time: 25mins

Name
Class
Date
1.

Any substance that causes your immune system to produce antibodies against it. Maybe a foreign substance from the environment, such as chemicals, bacteria, viruses, or pollen.

a)

Vaccine

b)

Toxin

c)

Antibody

d)

Antigen

2.

Also known as an immunoglobulin (Ig), this is a large, Y-shaped protein produced by plasma cells that are used by the immune system to identify and neutralize pathogens such as bacteria and viruses.

a)

B cells

b)

T cells

c)

Antibody

d)

Antigen

3.

An immunity that is the type of host defense that is always present in healthy individuals. It is always ready and prepared to block the entry

a)

Innate immunity

b)

Adaptive immunity

c)

Humoral Immunity

d)

Cell-mediated immunity

4.

An immunity that is a type of host defense that always require activation and stimulation of the host tissue by pathogens or harmful materials

a)

Innate immunity

b)

Adaptive immunity

c)

Native immunity

d)

Humoral Immunity

5.

An immune response that is mediated by secreted antibodies produced in the cells of the B lymphocyte lineages (B cells).

a)

Self Immunity

b)

Innate immunity

c)

Humoral Immunity

d)

Cell-mediated immunity

6.

An immune response that involves the activation of T lymphocytes (Cytotoxic T and Helper T) and the release of various cytokines in response to an antigen

a)

Cellular immunity

b)

Humoral Immunity

c)

Self Immunity

d)

Natural Immunity

7.

Ensures that immune response are precisely targeted to microbial pathogens

a)

Specificity

b)

Avidity

c)

Diversity

d)

Memory

8.

A person who took a drug that destroys the thymus would most likely ___.

a)

lack class I MHC molecules on cell surfaces

b)

be unable to genetically rearrange antigen receptors

c)

be unable to differentiate and mature T cells

d)

lack innate immunity

9.

The activation of helper T cells is likely ________.

a)

when an antigen is displayed by a dendritic cell

b)

when a cytotoxic T cell releases cytokines

c)

when natural killer cells come in contact with a tumor cell

d)

in the bone marrow during the self-tolerance test

10.

Which statement best describes the difference in responses of effector B cells (or plasma cells) and cytotoxic T cells?

a)

Effector B cells secrete antibodies that are specific for a certain pathogen; cytotoxic T cells kill pathogen-infected host cells.

b)

Effector B cells kill pathogens directly; cytotoxic T cells kill host cells.

c)

Effector B cells confer active immunity; cytotoxic T cells confer passive immunity.

d)

Effector B cells carry out the cell-mediated response; cytotoxic T cells carry out the humoral response.

11.

You and a friend were in line for a movie when you noticed the woman in front of you sneezing and coughing. Both of you were equally exposed to the woman's virus, but over the next few days, only your friend acquired flu-like symptoms and was ill for almost a week before recovering. Which one of the following is a logical explanation for this?

a)

Your friend had an autoimmune disorder.

b)

Your friend had allergies.

c)

Your friend had antibodies to that virus.

d)

You had an adaptive immunity to that virus.

12.

Which of the following is a TCR co receptor?

a)

alpha/beta

b)

alpha/beta + gamma/epsilon, zetax2, delta/epsilon + CD4/CD8

c)

alpha/beta + gamma/epsilon, zetax2, delta/epsilon

d)

CD4/CD8

13.

Which of the following is NOT a possible scenario when a pathogen has entered into blood stream?

a)

Antigen-Macrophage>Tcell>Bcell>sIg>complement system> inflammation

b)

Antigen-Tcell>Bcell> sIg>complement system> inflammation

c)

Antigen-Bcell>Tcell>Bcell> sIg>complement system> inflammation

d)

Antigen-Neutrophils>phagocytosis>Macrophage>>Tcell>Bcell>sIg>complement system> inflammation

14.

Antigen contact points in the Variable region are referred to as

a)

Complementary regions

b)

Complementary determining regions

c)

Complementarity determining regions

d)

Epitopes

15.

CD4 markers are found in which cell

a)

helper

b)

regulatory

c)

cytotoxic

d)

memory

16.

Cells that physically and chemically attack antigens

a)

Helper T cells

b)

Memory T cells

c)

cytotoxic T cells

d)

Regulatory T cells

17.

Cells that activate T and B cell responses

a)

Helper T cells

b)

Memory T cells

c)

cytotoxic T cells

d)

Regulatory T cells

18.

Subclasses of T cells that control immune response

a)

Helper T cells

b)

Memory T cells

c)

cytotoxic T cells

d)

Regulatory T cells

19.

Cells that retain memory of previous antigens and respond by cloning themselves

a)

Helper T cells

b)

Memory T cells

c)

cytotoxic T cells

d)

Regulatory T cells

20.

Immunity provided by cytotoxic T cells; Defends against abnormal cells and pathogens inside cells

a)

cell mediated immunity

b)

antibody mediated immunity aka humoral

21.

Type of immunity provided by B cells; Defends against antigens and pathogens in body fluids

a)

cell-mediated immunity

b)

antibody-mediated immunity aka humoral

22.

Class II MHC proteins are found only where?

a)

membranes of non nucleated cells

b)

membranes of antigen-presenting cells

c)

membranes of nucleated cells

d)

membranes of lymphocytes

23.

What are the type of T Cell CD Markers?

a)

CD4

b)

CD12

c)

CD8

d)

CD3

24.

CD8 T cells can produce which cells

a)

memory

b)

regulatory

c)

cytotoxic

d)

helper

25.

Cell that perform immune surveillance

a)

helper cells

b)

memory

c)

cytotoxic

d)

regulatory

26.

Cytotoxic T cells release perforins and cytokines and trigger

a)

apoptosis

b)

apostosis

27.

Produced simultaneously with cytotoxic T cells

a)

Memory

b)

Regulatory

c)

Helper

28.

Activation of CD4 T cells produces

a)

helper

b)

regulatory

c)

memory

d)

cytotoxic

29.

Which is not a function of an interleukin

a)

increases T cell sensitivity

b)

Enhancing innate immunity

c)

stimulating B cell activity

d)

enhancing adaptive immunity

e)

suppressing immune system and shortening immune response

30.

Largest and most diverse class of antibodies

a)

IgM

b)

IgG

c)

IgD

d)

IgA

31.

Antibody stimulates cell to accelerate inflammation

a)

IgE

b)

IgM

c)

IgA

d)

igG

32.

Binding of this immunoglobulin plays a role in sensitization of the B cell

a)

IgM

b)

IgA

c)

IgG

d)

IgD

33.

First antibody to be secreted after an antigen is encountered

a)

IgG

b)

IgD

c)

IgA

d)

IgM

34.

Found primarily in glandular secretions and attacks pathogens before they gain access to internal tissues

a)

IgG

b)

IgM

c)

IgA

d)

IgD

35.

What shape describes an antibody?

a)

Z shaped

b)

Y shaped

c)

W shaped

d)

T shaped

36.

The immune response that defends against antigens dissolved in body fluids is called:

a)

inflammatory response

b)

interferons

c)

humoral response

d)

cell mediated response

37.

Which of the following plays the biggest role in humoral immunity?

a)

mast cells

b)

cytotoxic T cells

c)

B cells

d)

platelets

38.

Which of the following plays the biggest role in cell mediated immunity?

a)

mast cells

b)

cytotoxic T cells

c)

B cells

d)

platelets

39.

A CD4+ helper T cell is involved in which of the following immune responses?

a)

cell mediated immunity

b)

humoral immunity

c)

both

d)

neither

40.

Which type of antigen-presenting molecule is found only on macrophages, dendritic cells, and B cells?

a)

MHC class 1

b)

MHC class 2

c)

T-cell receptor

d)

B-cell receptor

41.

MHC II molecules present

a)

processed foreign antigens from proteasomes.

b)

antibodies.

c)

T cell receptors.

d)

processed foreign antigens from phagolysosomes

42.

CD4 T cells are generally restricted by

a)

CD-1

b)

MHC class 1

c)

MHC class II

d)

β2 microglobulin

43.

A single antigen molecule may be composed of many individual

a)

MHC class 2

b)

epitopes

c)

RIG-like receptors

d)

T-cell receptors

44.

Microfold cells (or M cells) are found in the gut-associated lymphoid tissue (GALT) of the Peyer's patches in the small intestine, and in the mucosa-associated lymphoid tissue (MALT) of other parts of the gastrointestinal tract

a)

True

b)

False

45.

Immunoagglutination tests goal :

a)

detect Ag-Ab complexes

b)

identify an Ag, in this case Ag1 is known and Ag2 is unknown

c)

determine if there is a kinship between two Ag

46.

How do cytotoxic T cells destroy infected/cancerous cells?

a)

Release free radicals onto the cell

b)

Insert pore like structures called Perforins into their membranes

c)

Engulf the cell by phagocytosis

d)

Release antibodies which cause the cell to burst.

47.

T cells require passage through thymus to complete their maturation

a)

True

b)

False

48.

The lymphatic cells reach the lymp nodes via

a)

High endothelial venules

b)

arterioles

49.

MHC II molecules present

a)

processed foreign antigens from proteasomes.

b)

antibodies.

c)

T cell receptors.

d)

processed foreign antigens from phagolysosomes

50.

Which type of antigen-presenting molecule is found on all nucleated cells?

a)

MHC class 1

b)

MHC class 2

c)

B cell receptor

d)

antibodies