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Worksheets

semi fi myco

Total questions: 60

Worksheet time: 30mins

Name
Class
Date
1.

Disease caused by HSV-2 is

a)

- aseptic meningitis

b)

- encephalitis

c)

- shingles

2.

The disease caused by EBV

a)

- encephalitis

b)

- aseptic meningitis

c)

disseminated disease in immunocompromised

3.

The disease caused by VZV

a)

- encephalitis

b)

- shingles

c)

- aseptic meningitis

4.

The disease caused by HSV-1

a)

- shingles

b)

- encephalitis

c)

- aseptic meningitis

5.

The target cells type for latency of HHV-7 is/are: (1) monocytes (2) endothelial (3) epithelial (4) T lymphocytes

a)

1,3

b)

2,4

c)

3

d)

4

6.

Infection's caused by CMV: (1) infectious mononucleosis-like illness (2) infectious mononucleosis (3) congenital birth defects (4) kissing disease

a)

1,2,3

b)

2,3,4

c)

2,3

d)

3,4

7.

The virion of a herpes virus composed of the following: (1) the capsid (2) the tegument (3) nucleic acid core (4) envelope

a)

1,2,3,4

b)

2,3,4

c)

3,4

d)

2,4

8.

Herpes viruses that share the same several viral characteristics: (1) HSV-3 (2) HSV-1 (3) HSV-4 (4) HSV-2

a)

1,2

b)

3,4

c)

2,4

9.

The disease caused by CMV

a)

- encephalitis

b)

- aseptic meningitis

c)

disseminated disease in immunocompromised patient

10.

This can be found between the envelope and the nucleocapsid of some enveloped virus

a)

- capsid

b)

- matrix protein

c)

- glycoprotein

11.

Which of the following states the principle regarding viral nucleic acid

a)

purified viral nucleic acid from any virus is usually infectious

b)

- viruses contain both RNA and DNA

c)

some viruses contain a segmented genome

12.

Viruses belonging to which of the following group are likely to establish latent infection

a)

- influenza virus

b)

- herpes viruses

c)

- gastrointestinal viruses

13.

The clinical manifestations of HAV depend on the

a)

- age of the host

b)

- gender of the host

c)

- environmental temperature

14.

Primary route of transmission of HBV is through

a)

- water borne

b)

- person contact

c)

- percutaneous exposure to blood

15.

This happens after local viral infection

a)

- lysis

b)

viremia

c)

- immunopathologic mechanism

16.

These are non-structural elements early proteins in the macromolecular synthesis

a)

- enzymes

b)

- syncytia

c)

- envelopes

17.

Envelope of a virus from host cell membrane are acquired during viral

a)

- budding

b)

tropism

c)

uncoating

18.

HEV primary mode of transmission is

a)

consumption of water contaminated with soil

b)

consumption of water contaminated with feces

c)

consumption of water contaminated with urine

19.

It occurs early during the onset of clinical symptoms with Norovirus and Sapovirus infection

a)

- maximum viral shedding

b)

- minimal viral shedding

c)

- immediate viral shedding

20.

The most common congenital infection is caused by:

a)

- herpes simplex virus type 2

b)

- varicella-zoster

c)

- cytomegalovirus

21.

Which of the following statement/s about rhinoviruses is/are true: (1) sensitive to a pH of lower than 6 (2) the major cause of common cold (3) small envelope virus (4) small naked virus closely related to the enterovirus

a)

1,2

b)

3,4

c)

1,2,3,4

d)

4,3,2,1

22.

Secondary viremia may occur in the following variety of tissues: (1) brain tissues (2) kidneys (3) salivary glands (4) eyes

a)

1,2,3

b)

2,3,4

c)

3,4

d)

4,3

23.

Which of the following statements is/are TRUE: (1) viruses contains DNA or RNA (2) the nucleic acid of a virus is surrounded by a protein coat (3) viruses cause the synthesis of specialized infectious elements (4) viruses multiply inside living cells using viral mRNA, tRNA, and ribosomes

a)

1,2,3

b)

3,4

c)

2,4

24.

Steps involved in virus pathology include: (1) attachment (2) release (3) penetration (4) mitosis

a)

1,3

b)

2,4

c)

1,2,3

d)

4

25.

The following is/are are functions of a glycoprotein spikes: (1) for lipid envelope. will assist the stabilization of attachment (2) accounts for most of the mass of a virus (3) facilitate viral entry during attachment of the host cell (4) it protects the protein subunits called the capsomeres

a)

1,2

b)

1,3

c)

2,3

d)

2,4

26.

What can be observed from the surface of the virus that functions as projection from attachment or as enzyme

a)

capsid

b)

- envelopes

c)

- glycoprotein spikes

27.

An infected host cells will give in as many as how many virions

a)

1,000

b)

10,000

c)

100,000

d)

1,000,000

28.

Viruses that has been known by veterinary virologists as a major animal pathogens

a)

- filoviruses

b)

- caliciviruses

c)

- arenaviruses

29.

Virally encoded glycoprotein hemagglutinins in an infected cell is caused by

a)

adenoviruses

b)

- influenza virus

c)

- rhinovirus

30.

Six months after infection of HBsAg indicates that the patient is alan

a)

- acute carrier

b)

- chronic carrier

c)

- chronic infected

31.

Rotavirus is most often associated with

a)

- infant diarrhea

b)

- paralysis of children

c)

- infant respiratory infection

32.

Viruses that attack bacteria are called

a)

virocyte

b)

- bactenophages

c)

- neutrophic viruses

33.

Viruses resemble living things in that they

a)

- are motile

b)

- are crystalline

c)

- reproduce

34.

An example of lysogeny in animals could be

a)

- reproduce

b)

- slow viral infection

c)

- latent viral infections

35.

Place the following in order in which they are found in a host cell: (1) capsid proteins: (2) infective phage particles: (3) phage nucleic acid

a)

1,2,3

b)

3,1,2

c)

2,3,4

d)

4

36.

This will occur after local viral infection

a)

- fever

b)

- viremia

c)

- bacteremia

37.

The genome of a virus may consist of

a)

- amino acids

b)

- DNA or RNA

c)

- mitochondria

38.

This can be found between the envelope and the nucleocapsid of some enveloped virus

a)

- glycoprotein

b)

- matrix protein

c)

- capsid

39.

Which of the following states the principle regarding viral nucleic acid

a)

some viruses contain a segmented genome

b)

purified viral nucleic acid from any virus is usually infectious

c)

- viruses contain both RNA and DNA

40.

Viruses belonging to which of the following group are likely to establish latent infection

a)

- influenza virus

b)

- herpes viruses

c)

- gastrointestinal viruses

41.

The clinical manifestations of HAV depend on the

a)

- gender of the host

b)

- age of the host

c)

- environmental temperature

42.

HEV can cause high fatality rate among

a)

- infants

b)

- toddlers

c)

- pregnant women

43.

This is to be replicated in order to provide genomes for progeny virions

a)

- protein polymers

b)

- viral budding

c)

- viral nucleic acid

44.

A bacteriophage is

a)

a bacterium that attacks another bacterium

b)

- a virus that attacks a bacterium

c)

- a virus that attacks another virus

45.

The clinical spectrum of HAV infection ranges from

a)

asymptomatic infection to fulminant hepatitis

b)

fulminant infection to asymptomatic hepatitis

c)

fulminant hepatitis to asymptomatic infection

46.

This can be found between the envelope and the nucleocapsid of some enveloped virus

a)

- glycoprotein

b)

- matrix protein

c)

- herpes viruses

47.

The following are caused by Herpes B virus: (1) severe encephalitis (2) mild encephalitis (3) fatal encephalitis (4) acute encephalitis

a)

1,2

b)

1,3

c)

1,4

d)

2,1

48.

The following is/are characteristics of HHV-6: (1) belongs to genus Roseolovirus (2) cause exanthema subitum (3) nearly 100% of humans are exposed by the age of 3 (4) belongs to the gamma-herpes subfamily

a)

1,2,3

b)

1,3

c)

2,4

49.

The diseases causes by HHV-8: (1) castleman's disease (2) primary effusion lymphosis (3) kaposi's sarcoma (4) burkitt's lymphoma

a)

1,2,3

b)

2,3,4

c)

4,3,2

50.

The Adenovirus serotypes 40 and 41 caused gastroenteritis in: (1) young children (2) aged (3) infants (4) adults

a)

1,3

b)

1,4

c)

1,2

d)

1

51.

Which of the following statements about RSV is/are true: (1) infection confer immunity (2) high titers are present in respiratory tract secretions in children (3) the virus contains a surface protein F/Fraction (4) cause bronchiolitis in young children

a)

1,2,3

b)

2,3,4

c)

3

d)

4

52.

Outbreaks of astroviral disease usually occur in residential facilities for the: (1) day-care centers (2) nursing homes (3) hospitals (4) elderly

a)

1,3

b)

1,2,3

c)

1,2,3,4

53.

Which of the following statements about rhinoviruses is correct

a)

- there are three antigenic types

b)

they do not survive on environment surfaces

c)

they share physiochemical similarities with coronaviruses

54.

A 36-year old man enjoyed a meal of raw oysters. Twenty-four hours later, he became ill, with a sudden onset of vomiting, diarrhea, and headache. The most likely cause of his gastroenteritis is

a)

- astrovirus

b)

- norwalk virus

c)

- hepatitis A virus

55.

This viral gastroenteritis agent has a segmented, double-stranded RNA genome and a double-shelled capsid. It is a member of which virus family

a)

- reoviridae

b)

caliciviridae

c)

- astroviridae

56.

Rotavirus and Norwalk virus are distinctly different viruses. However, they share which one of the following characteristics

a)

- fecal-oral mode of transmission

b)

they mainly cause disease in infants and young children

c)

they induce generally mild disease in young children

57.

A 3 month-old infant has watery diarrhea and fever for 10 days. Rotavirus or adenovirus types 40 and 41 are the suspected agents. What type of specimen would be most appropriate for detection of adenovirus 40 and 41 infection in this patient

a)

blood

b)

urine

c)

stool

58.

A previously healthy 3-year old boy develops a classic viral childhood illness. Which of the following primary viral infection of childhood is usually symptomatic

a)

- cytomegalovirus

b)

- Epstein-barr virus

c)

- varicella-zoster virus

59.

HDV is found only in patients who have either acute or chronic infection with HBV. The following is most correct

a)

HDV depends on HBV surface antigen for virion formation

b)

HDV induces an immune response indistinguishable from that induced by HBV

c)

- HDV is defective mutant HBV

60.

A middle-aged man complained of acute onset of fever, nausea, and pain in the right upper abdominal quadrant. There was jaundice, and dark urine had been observed several days earlier. A laboratory test was positive for HAV IgM antibody. The physician can tell the patient that

a)

he will probably develop chronic hepatitis

b)

he will be at high risk of developing hepatocellular carcinoma

c)

he may transmit the infection to family members by person-to-person spread for up to 2 week