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3.3 DNA to Proteins

Total questions: 24

Worksheet time: 12mins

Name
Class
Date
1.

Which of these is NOT a difference between immature mRNA and mature mRNA?

a)

Mature mRNA has a poly adenosine tail on the 3' end and immature mRNA does not.

b)

Mature mRNA has a methyl-guanosine cap on the 5' end and immature mRNA does not.

c)

Mature mRNA is folded into a specific shape due to its properties and immature mRNA is not.

d)

Mature mRNA is shorter than immature mRNA because the Introns are removed.

e)

Mature mRNA can leave the nucleus and immature mRNA cannot.

2.

DNA contains all of the following nitrogen-containing bases EXCEPT

a)

adenine.

b)

uracil.

c)

guanine.

d)

adenine.

e)

thymine.

3.

Rosalind Franklin used which technique to determine many of the physical characteristics of DNA?

a)

transformation

b)

transmission electron microscopy

c)

density-gradient centrifugation

d)

X-ray diffraction

e)

all of these

4.

Each DNA strand has a backbone that consists of alternating

a)

covalent and ionic bonds.

b)

nitrogen-containing bases.

c)

hydrogen bonds.

d)

sugar and phosphate molecules.

e)

covalent and hydrogen bonds.

5.

In the spiral staircase model of DNA, the rungs are

a)

deoxyribose sugars.

b)

nucleotide base pairs.

c)

phosphate groups.

d)

composed of all of these.

6.

RNA polymerase assembles new strands

a)

in a 5' to 3' direction only.

b)

in a 5' to 3' direction building one strand and a 3' to 5' direction building the other strand.

c)

in a 5' to 3' direction building the first half of a strand and a 3' to 5' direction building the second half of a strand.

d)

in a 3' to 5' direction building the first half of a strand and a 5' to 3' direction building the second half of a strand.

e)

in a 3' to 5' direction on the "old" 3' to 5' strand.

7.

Franklin worked most closely with

a)

Wilkins.

b)

Watson.

c)

Crick.

d)

Chargaff.

e)

none of these.

8.

A linear stretch of DNA that specifies the sequence of amino acids in a polypeptide is called a(n)

a)

codon.

b)

intron.

c)

messenger.

d)

gene.

e)

enzyme.

9.

The two steps of transcription followed by translation

a)

explain the structural complexity of genes.

b)

describe the flow of genetic information.

c)

are based upon the role of proteins in controlling life.

d)

do not explain how genes function.

e)

explain evolution in terms of molecular biology.

10.

All of the different kinds of RNA are transcribed in the

a)

mitochondria.

b)

cytoplasm.

c)

ribosomes.

d)

nucleus.

e)

endoplasmic reticulum.

11.

DNA and RNA are alike in

a)

the ribose sugar.

b)

all the nitrogenous bases used to assemble the genetic code.

c)

the number of strands.

d)

their function in genetics.

e)

none of these.

12.

The relationship between strands of RNA and DNA is

a)

antagonistic.

b)

opposite.

c)

complementary.

d)

an exact duplicate.

e)

unrelated.

13.

Which of the following dominates in the process of transcription?

a)

RNA polymerase

b)

DNA polymerase

c)

helicase

d)

transfer RNA

e)

all of these dominate in the process of transcription

14.

Before messenger RNA is mature,

a)

all exons are deleted and removed.

b)

a cap and a tail are provided.

c)

anticodons are assembled.

d)

the transfer RNA transfers the messenger RNA to the ribosome.

e)

the single RNA strand duplicates itself in much the same way as DNA.

15.

There are how many different kinds of amino acids in proteins?

a)

3

b)

6

c)

12

d)

20

e)

28

16.

Of all the different codons that exist, three of them

a)

are involved in mutations.

b)

do not specify a particular amino acid.

c)

cannot be copied.

d)

provide instructions such as STOP.

e)

do not specify a particular amino acid AND provide instructions such as STOP.

17.

Which of the following carries amino acids to ribosomes, where amino acids are linked into the primary structure of a polypeptide?

a)

mRNA

b)

tRNA

c)

hnRNA

d)

rRNA

e)

all of these

18.

Which event occurs at the P site of a ribosome?

a)

Peptide bonds form.

b)

Free amino acids bind to the mRNA binding site.

c)

Anticodons bind to complementary codons.

d)

A STOP codon enters the ribosome.

e)

The ribosomal subunits release.

19.

During the termination stage of Translation

a)

a STOP codon enters the ribosome.

b)

release factors bind the ribosome.

c)

mRNA detaches from the ribosome and the polypeptide chain.

d)

ribosomal subunits separate.

e)

all of these occur.

20.

The following questions refer to the genetic code table above.

    AUGCGUCCA

The sequence of amino acids specified by this mRNA is

a)

serine − histidine − lysine.

b)

valine − arginine − leucine.

c)

methionine − arginine − proline.

d)

methionine − alanine − serine.

21.

There are how many different kinds of RNA codons?

a)

22

b)

3

c)

64

d)

12

22.

If the DNA triplets are TAC−CGT, the mRNA codons are

a)
AUG−GCA
b)
GCA−AUG
c)
CGT−TAC
d)
TAC−CGT
23.

Post-translational modifications include all of the following except

a)

Folding

b)

Modification in the Golgi

c)

Phosphorylation

d)

Removal of Introns

24.

Post-transcriptional modifications include all of the following except

a)

folding

b)

intron splicing

c)

3' polyadenylation

d)

5' capping