Free Printable MUTATION

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MUTATION

Total questions: 20

Worksheet time: 10mins

Name

Class

Date

Any change in the sequence of DNA is...

transgenic shift

Single Genotype

Monohybrid Trait

Mutation

Where do mutations occur?

DNA and RNA

DNA

RNA

mRNA and tRNA

What type of mutation is shown in the diagram?

Point mutation - missense

Frameshift Mutation - deletion

Frameshift Mutation - addition

Point mutation - nonsense

A type of mutation that affect every codon beyond the point of mutation.

Point Mutation

Silent Mutation

Nonsense Mutation

Frameshift Mutation

What type of mutation is this?

Nonsense mutation

Missense mutation

Silent mutation

Frameshift mutation

DOES THE DNA MUTATION ALWAYS ALTER THE AMINO ACID SEQUENCE?

Yes

Which shows a mutated segment of DNA?
ATTCGC

UAAGCG

TAAGCG

TAGGCG

Mutations affect the ________ of a protein. Because of this the proteins ______ is affected as well.

gene, function

sequence, gene

shape,function

if a single nucleotide base is added or deleted the entire reading frame will?

shift, causing a frameshift mutation

move, causing a delection

move, causing an addition

shift, causing a deletion

10.

What situation causes a deletion?

Part of the chromosome is missing

Part of the chromosome is attached backwards

Part of the chromosome breaks off and attaches to a different chromosome

Part of a chromosome is duplicated

11.

Why are insertion and deletion mutations so harmful?

They change all of the codons from the mutation on down the line, which changes the amino acid sequence

They insert things that an organism doesn't need.

They often delete things that organisms need.

Insertion and deletions are not any more harmful than substitution mutations.

12.

Point mutation involves

deletion

insertion

duplication

changes in single base pair

13.

Which of the following genetic disorders is caused by chromosomal deletion?

Down syndrome (Trisomy 21)

Turner syndrome (Monosomy X)

Cri-du-chat syndrome

Chronic Myelogenous Leukemia (CML)

14.

The failure of one or more pairs of homologous chromosomes or sister chromatids to separate "normally" during meiosis is called _____________________.

nondisjunction

duplication

deletion

translocation

15.

Non-disjunction involving the X chromosomes occurs during oogenesis and produces two kinds of eggs, XX and O (no X chromosomes). If normal sperms fertilize the two types of eggs, which are the possible genotypes produced?

XX AND XY

XYY AND XO

XXY AND XO

YY AND XO

16.

Notice the abnormal 23rd chromosome. This individual suffers from which chromosomal genetic disorder?

Klienfelter's Syndrome

Down Syndrome

Cris-du-Chat Syndrome

Andrew's Syndrome

17.

What type of chromosomal mutation is this?

Translocation

Inversion

Deletion

Duplication

18.

DNA molecule segment is : TTACGCAAG
The mutated DNA segment is TTACGCAAC. This is an example of ___ mutation.

Base Substitution

Base Insertion

Base Inversion

Translocation

19.

A mutation that does NOT alter the protein production is called a

silent mutation

nonsense mutation

missense mutation

inversion mutation

20.

Which ONE is NOT a type of gene mutation?

Base substitution

Base duplication

Base deletion

Base inversion

Reset

MUTATION

Total questions: 20

Worksheet time: 10mins

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