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WorksheetsKaryotypes and Aneuploidy Quiz
Total questions: 66
Worksheet time: 2hrs 12mins
What is a karyotype?
A type of plant species
A type of protein found in cells
A type of weather pattern
A visual appearance of the chromosomes in the cell nuclei of an organism
What are chromosomal abnormalities and how do they occur?
Changes in the number or structure of chromosomes due to errors in cell division, exposure to harmful substances, or genetic factors.
Chromosomal abnormalities are caused by eating too much sugar
Chromosomal abnormalities occur due to excessive exercise
Chromosomal abnormalities are caused by exposure to sunlight
What is trisomy and monosomy? Provide examples of each.
Trisomy 8 and Monosomy 9
Trisomy 18 (Edwards syndrome) and Monosomy 13 (Patau syndrome)
Trisomy 16 and Monosomy 22
Trisomy 21 (Down syndrome) and Monosomy X (Turner syndrome)
Explain Klinefelter syndrome and its genetic cause.
Klinefelter syndrome is caused by having an extra Y chromosome in males.
Klinefelter syndrome is caused by a missing X chromosome in males.
Klinefelter syndrome is caused by the absence of the Y chromosome in males.
Klinefelter syndrome is caused by the presence of an extra X chromosome in males.
Describe Turner syndrome ____.
Turner syndrome is a genetic condition that affects females, where one of the X chromosomes is missing or partially missing.
Turner syndrome is a condition that affects males, causing them to be taller than average and have increased fertility.
Turner syndrome is a condition that has no physical effects on individuals, only affecting their mental health.
Turner syndrome is a condition that causes individuals to be male or female with an extra X chromosome,
What are the characteristics of Down syndrome?
Intellectual disability, distinctive facial features, and certain health problems
No intellectual disability, no distinctive facial features, and no health problems
Low intelligence, normal facial features, and no health problems
High intelligence, average facial features, and no health problems
How is karyotyping used in diagnosing chromosomal abnormalities?
It is used to count the number of genes in a chromosome
It is used to measure the length of the chromosomes
It helps to identify any missing, extra, or abnormal chromosomes.
It helps to determine the blood type of an individual
Discuss the impact of aneuploidy on human health.
Aneuploidy is beneficial for human health
Aneuploidy can lead to genetic disorders and developmental abnormalities, impacting human health.
Aneuploidy has no impact on human health
Aneuploidy only affects physical appearance, not health
The difference between autosomal and sex chromosome aneuploidy:
Autosomal aneuploidy involves an abnormal number of chromosomes in the non-sex chromosomes, while sex chromosome aneuploidy involves an abnormal number of chromosomes in the sex chromosomes.
Autosomal aneuploidy involves an abnormal number of chromosomes in the sex chromosomes, while sex chromosome aneuploidy involves an abnormal number of chromosomes in the non-sex chromosomes.
Autosomal aneuploidy and sex chromosome aneuploidy are the same and have no difference.
Autosomal aneuploidy only affects females, while sex chromosome aneuploidy only affects males.
What are the ethical considerations surrounding prenatal testing for aneuploidy?
Increased risk of miscarriage
Limited access to prenatal testing
Financial burden on the healthcare system
Ethical considerations include potential discrimination, emotional impact, and selective termination.
Which Genetic syndrome can we observe in this karyotype?
Turner
Klinefelter's
Down
Edward's
Which Genetic syndrome can we observe in this karyotype?
Turner
Edward's
Pateau
Klinefelter's
What is the gender of this person?
Male
Female
What syndrome does this person have and what is their gender?
Male
Female
Edwards
pateau
down
Pairs of similar chromosomes are called...
homologous chromosomes
sister chromatids
What is an organized picture of all of an organism’s homologous chromosome pairs lined up with each other?
Pedigree
Karyotype
Which of the following is used to determine genetic defects or if an extra or missing chromosome exist in an organism?
Pedigree
Punnett Square
Karyotype
Which type of chromosome determines if someone will be male or female?
autosomes
sex chromosomes
Which set of chromosomes represents a male?
XX
XY
Which set of chromosomes represents a female?
XX
XY
Cells that contain 2 sets of chromosomes are called ...
haploid
diploid
How many pairs of autosomes do human cells contain?
22
1
46
How many pairs of sex chromosomes do human cells contain?
22
1
46
How many total chromosomes do human cells contain?
23
46
What is a?
Replicated chromosome
sister chromatids
Homologous chromosomes
What is c?
Replicated chromosome
sister chromatids
Homologous chromosomes
What is d?
Replicated chromosome
sister chromatids
Homologous chromosomes
What is b?
centriole
centromere
What is the mutation in this persons chromosomes?
There is only one X
7 is shaped like a hockey stick
There's an extra 21
1 is too curved
This disorder is called "Cry of the cat", can you find the chromosomal mutation?
There are too many chromosomes
They are missing the Y chromosome
Chromosome 1 is bent
Chromosome 5 is too short (missing a piece)
This person has Angel Mans syndrome. What is different about their chromosomes?
Chromosome 1 is misshapen
Chromosomes 21 is too small
They are missing one of chromosome 15
Chromosomes 7 and 8 look weird
This is known as Edwards Syndrome, can you identify the chromosomal mutation?
Chromosomes 1 and 2 are bent
There is no Y chromosome
This persons chromosomes are normal
There are 3 of chromosomes 18
Which phase of the cell cycle is when scientists take a picture to construct a karyotype?
Interphase
Prophase
Metaphase
Anaphase
Homologous pairs:
(select all that apply)
Have the same genes on them
May have different alleles
Each comes from one parent
Combine to give you your genotypes
Which of the following is a result of a nondisjunction?
Klinefleter syndrome
Sickle cell anemia
Cystic fibrosis
Hemophilia
44 + X
Klinfelter's syndrome
Cystic Fibrosis
Down's Syndrome
Turner's Syndrome
44 + XXY
Klinfelter's syndrome
Cystic Fibrosis
Down's Syndrome
Turner's Syndrome
In which phase does crossing-over happen?
Prophase I
Prophase II
Metaphase I
Anaphase II
During meiosis, if an organism has 10 chromosomes, how many will the new daughter cells have?
10
8
5
2
This term refers to half the normal chromosome number
haploid
2N
diploid
3N
The exchange of genetic information that insures that every gamete is unique is referred to as
mitosis
meiosis
reduction division
crossing over
All sperm and egg cells are genetically identical.
TRUE
FALSE
The term that refers to a cell that has its full or complete number of chromosomes is
diploid
N
gamete
haplpoid
At the end of meiosis, how many complete/operational sex cells are created for each original cell?
2 for males; 2 for females
1 for males; 4 for females
4 for males; one for females
1 for males; 1 for females
Sea turtles have 56 chromosome in their somatic cells. How many chromosomes are in their gametes?
28
56
112
46
A pair of identical chromosomes (one inherited from mom and one inherited from dad) are called ______________________________.
sister chromotids
centromeres
homologous chromosomes
autosomes
The failure of one or more pairs of homologous chromosomes or sister chromatids to separate "normally" during meiosis is called _____________________.
nondisjunction
anaphase I
nondiploidy
karyotype
Nondisjunction
When a segment of a chromosome breaks off.
When a segment of a chromosome breaks off, flips, and reattaches.
When a segment of a chromosome breaks and attaches to a non homologous chromosome.
When entire chromosomes don't separate evenly during meiosis.
When a segment of a chromosome is copied or doubles.
This Karyotytpe belongs to which syndrome?
Turner Syndrome
Edwards Syndrome
Patau Syndrome
Down Syndrome
Klinefelter Syndrome
This karyotype belongs to which syndrome?
Patau's Syndrome
Edward's Syndrome
Klinefelter Syndrome
Down Syndrome
Non-disjunction involving the X chromosomes occurs during oogenesis and produces two kinds of eggs, XX and O (no X chromosomes). If normal sperms fertilize the two types of eggs, which are the possible genotypes produced?
XX AND XY
XYY AND XO
XXY AND XO
YY AND XO
In a _______________________ one chromosome of a homologous pair is missing. In a ______________________the affected person has three copies of one of the chromosomes instead of two. Down syndrome is an example of a _________________ while Turner syndrome is an example of a _____________________.
monosomy, trisomy, trisomy, monosomy
trisomy, monosomy, monosomy, trisomy
The inheritance of an extra chromosome is called:
monosomy
trisomy 21
aneuploidy
trisomy
A diploid cell that is missing one chromosome of a homologous pair is called a:
aneuploidy
monosomy
nondisjunction
trisomy
The karyotype in the diagram is from an infant with a high-pitched cry that sounds like that of a cat. Which syndrome do they have?
Klinefelter
Down
Cris-du-chat
Turner
Select an example of aneuploidy:
Triploidy
Tetraploidy
Biploidy
Trisomy
Select an example of euploidy in humans:
44 XXY
44 XX
3n
44 X0
Which of these is not an indication for karyotyping?
Leukemia
Recurrent miscarriages
Cousin with chromosomal abnormality
First baby
The name given to cells: a) containing more than one pair of homologous chromosomes is (a) as we see in strawberries with 5n. b) containing one extra chromosome is known as a (b) , c) while containing one less chromosome is known as a (c) .
Nondisjunction in meiosis 1 means
50% of gametes will be normal, 50% will be trisomy
50% of gametes will be normal, 50% will be monosomy
50% of gametes will be missing a chromosome; 50% will have one extra chromosome
50% of gametes will be normal, 25% will be one extra chromosome, 25% will be missing a chromosome
Nondisjunction in meiosis 1 means
all gametes are affected with aneuploidy
half the gametes are affected with aneuploidy
all gametes are polyploid
all gametes are euploid (normal)
Nondisjunction in meiosis 2 means
all gametes are affected with aneuploidy
half the gametes are affected with aneuploidy
all gametes are polyploid
all gametes are euploid (normal)
Nondisjunction occurs in spermatogenesis meiosis 2. That means ___
50% will have 'n' chromosomes, 50% may have one extra chromosome
50% will have 'n' chromosomes, 50% may be missing a chromosome
50% are missing one chromosome ; 50% have one extra chromosome
50% of the gametes will be normal, 25% will have an extra chromosome is fertilized, 25% will be missing a chromosome
