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Chapter 14

Total questions: 94

Worksheet time: 3hrs 29mins

Name
Class
Date
1.

What are Nucleotides?

a)

Nucleotides are monomer components of nucleic acid

b)

Nucleotides are polymer components of nucleic acid

c)

Nucleotides are monomer components of proteins

2.

What is Deletion Mutation?

a)

a type of mutation that involves the addition of one or more nucleotides into a segment of DNA.

b)

a type of genetic mutation that involves the removal of a portion of the genetic material

c)

a mutation in which a single pair of nucleotides at a certain point in the gene sequence is altered.


3.

What is a nucleotide made up of?

a)

A protein, a phosphate, and a nucleic acid

b)

A sugar, a phosphate, and a nitrogenous base (adenine, thymine, cytosine, guanine, or uracil)

c)

A nucleic acid, a fatty acid, and a sugar

4.

Sugar and Phosphate come together to create what?

a)

A code of the DNA molecule

b)

A protein of the DNA molecule

c)

A backbone of the DNA molecule

d)

A nitrogen of the DNA molecule

5.

What are the nitrogen bases?

a)

The Code (information for life)

b)

The Protein

c)

The Backbone

d)

The Nitrogen

6.

What is DNA?

a)

DNA is a single strand

b)

DNA is a double helix polymer made up of repeating nucleotides (monomers) bound covalently to each other.

7.

What do the two polymer strands do?

a)

The two polymer strands run parallel from one another.

b)

The two polymer strands run vertically and horizontally

c)

The two polymer strands run in opposite directions. They are directional and antiparallel.

8.

What are the two polymer strands held together by?

a)

Held together by specific complementary hydrogen bonds between opposing nitrogen bases (A-T and C-G)


b)

Held together by specific nitrogen bonds between opposing hydrogen bases

9.

Thymine will always be with…

a)

Guanine (G to C)

b)

Cytosine (C to G)

c)

Adenine (T to A) or (A to T)

d)

Uracil

10.

Guanine will always be with…

a)

Guanine (G to C)

b)

Cytosine (C to G)

c)

Adenine (T to A) or (A to T)

d)

Uracil

11.

What is Conservative Replication?

a)

Parent strand unwinds and separates (relaxing) by actions of helicase (DNA)

b)

Original parent double strands remain intact and two completely new double helix strands are synthesized and created.

12.

What is Semi-Conservative Replication?

a)

Parent strand unwinds and separates (relaxing) by actions of helicase (DNA)

b)

Original parent double strands remain intact and two completely new double helix strands are synthesized and created.

13.

In Semi-Conservative Replication new DNA molecules will become

a)

New and identical

b)

Old and not identical

c)

Half old and half new and exactly identical

d)

half old and not identical

14.

How are new strands formed?

a)

Through nitrogen base pairing by actions of DNA polymerase

b)

Through complementary base pairing by actions of DNA polymerase (builds)

c)

Through protein base pairing by actions of DNA polymerase

15.

What does DNA Ligase do?

a)

Creates new DNA molecules

b)

Replicates and dying DNA molecules

c)

Creates new proteins

d)

Seals any breaks in the sugar-phosphate backbone.

16.

What does Replication do?

a)

Replication potentially shortens the ends of eukaryotic chromosomes.

b)

Replication creates eukaryotic chromosomes

c)

Replication replicates dying DNA molecules

17.

How are the ends of linear chromosomes maintained?

a)

Maintained by the action of the ribosomes

b)

Maintained by the actions of the DNA molecules

c)

Maintained by the action of the telomerase enzyme.

d)

Maintained by the actions of the fatty acids

18.

What is Dispersive Replication?

a)

Both original parent strands are created and incorporated into newly synthesized strands

b)

Both original parent strands are broken up into small pieces and incorporated into newly synthesized strands.

19.

What are Mutations?

a)

Mutations are changes in the protein sequence of the DNA strands

b)

Mutations are created only in animal cells

c)

Mutations are created in the fatty acid of the DNA strands

d)

Mutations are changes in the nucleotide sequence (info for life) of the DNA strands.

20.

Mutations can lead to what?

a)

Mutations can lead to changes in the protein sequence encoded by the DNA.

b)

Mutations can lead to creations in the protein sequence encoded by the DNA

c)

Mutations can only occur in animal cells

21.

What is Point Mutation?

a)

a type of mutation that involves the addition of one or more nucleotides into a segment of DNA.

b)

a type of genetic mutation that involves the removal of a portion of the genetic material

c)

a mutation in which a single pair of nucleotides at a certain point in the gene sequence is altered.

22.

What is Insertion Mutation?

a)

a type of mutation that involves the addition of one or more nucleotides into a segment of DNA.

b)

a type of genetic mutation that involves the removal of a portion of the genetic material

c)

a mutation in which a single pair of nucleotides at a certain point in the gene sequence is altered.

23.

What is Deletion Mutation?

a)

a type of mutation that involves the addition of one or more nucleotides into a segment of DNA

b)

a type of genetic mutation that involves the removal of a portion of the genetic material

c)

a mutation in which a single pair of nucleotides at a certain point in the gene sequence is altered.

24.

What is the location of Transcription

a)

In the cytoplasm and endoplasmic reticulum

b)

In the nucleus

25.

What is the location of Translation?

a)

In the cytoplasm and endoplasmic reticulum

b)

In the nucleus

26.

What is Central Dogma?

a)

genetic information flows only in one direction, from DNA, to RNA, to protein, or RNA directly to protein (from gene to protein)

b)

genetic information flows only in two directions, from DNA, to RNA, to tRNA

27.

What is a Fact about Translation

a)

DNA serves as a backbone to make mRNA

b)

DNA serves as a template to make tRNA

c)

DNA serves as a template to make mRNA

28.

Small Fact about Translation

a)
mRNA directs sequence of amino acids in a protein
b)

rRNA and tRNA assist

c)

mRNA and tRNA assist

29.

What does Genetic Code do?

a)

Translates proteins to amino acids

b)

Translates amino acids into fatty acids

c)

Translates from nucleic acids to amino acids

30.

What is a Triplet in Genetic Code?

a)

1 nucleotide sequence in DNA

b)

2 nucleotide sequences in DNA

c)

3 nucleotide sequence in DNA

d)

4 nucleotide sequence in DNA

31.

What is a codon?

a)

3 nucleotide sequence in DNA

b)

3 nucleotide sequence in mRNA

32.

How many amino acids are encoded in a codon?

a)

One Single Amino Acid

b)

Two Amino Acids

c)

Three Amino Acids

d)

Four Amino Acids

33.

A Ribonucleic acid (RNA)

a)

contains a protein

b)

Contains a sugar ribose

c)

Uses Thymine (uses T, C, G like DNA)

d)

Is single-stranded

e)

Uses Uracil (uses A, C, and G like DNA)

34.

Messenger RNA (mRNA)

a)

Is produced in the nucleus from DNA template

b)

Carries genetic message to lysosomes

c)

Is produced in the cytoplasmic reticulum from DNA Template

d)

Carries genetic message to ribosomes

35.

Transfer RNA (tRNA)

a)

Dissolves amino acids

b)

Produced in the nucleus from DNA template

c)

Transfers amino acids to ribosomes

d)

Produced in the endoplasmic reticulum

e)

Each type carries only one type of amino acid

36.

Ribosomal RNA (rRNA)

a)

Produced in the nucleolus of the nucleus from DNA template

b)

Joins with fatty acids to form ribosomes

c)

Ribosomes may be free or in polyribosomes (clusters) or attached to ER

d)

Joins with proteins to form ribosomes

37.

Is Messenger RNA (mRNA) a codon or anticodon?

a)

Codon

b)

Anticodon

38.

Is Transfer RNA (tRNA) a codon or anticodon?

a)

Codon

b)

Anticodon

39.

How many nucleotides make a codon?

a)

One

b)

Two

c)

Three

d)

Four

40.

Where is DNA found?

a)

In the Endoplasmic Reticulum

b)

In the Nucleus

41.

Where is RNA found?

a)

In the Endoplasmic Reticulum

b)

Nucleus

c)

Cytoplasm

42.

During transcription complementary _____ is made from a _______ ___________

a)

tRNA; DNA template

b)

mRNA; DNA template

c)

RNA; DNA template

43.

What happens during Transcription?

a)

RNA polymerase adds complementary nucleotides to make the mRNA

b)

Portion of DNA unwinds and unzips at the point of attachment of RNA polymerase

c)

mRNA joins in order to replicate the DNA strands

d)

Bases join in the ordwer dictated by the sequence of bases in the template DNA strand

44.

Transcription Initiation

a)

RNA polymerase adds complementary nucleotides (A, U, C, G) to make the mRNA

b)

Promoter is a piece of DNA upstream that indicates where the RNA polymerase should bind and start

c)

STOP

45.

Transcription Elongation

a)

Promoter is a piece of DNA upstream that indicates where the RNA polymerase should bind and start

b)

STOP

c)

RNA polymerase adds complementary nucleotides (A, U, C, G) to make the mRNA

46.

Transcription Termination

a)

Promoter is a piece of DNA upstream that indicates where the RNA polymerase should bind and start

b)

STOP

c)

RNA polymerase adds complementary nucleotides (A, U, C, G) to make the mRNA

47.

mRNA Processing

a)

Newly made premature mRNA must be processed

b)

Addition of a 5' methylguanosine cap and a 3' poly-A tail provides stability and protection (cytoplasm)

(Now mature mRNA leaves nucleus and associates with ribosome on cytoplasm)

c)

Processes proteins

48.

Intron Splicing

a)

coding regions for amino acids

b)

Removal of the non-coding regions

49.

Exons

a)

coding regions for amino acids

b)

Removal of the non-coding regions

50.

tRNA brings in what?

a)

proteins

b)

fatty acids

c)

energy

d)

amino acids

51.

Anticodon

a)

sequence of three nucleotides that corresponds with a specific amino acid or stop signal

b)

group of three bases complementary to a specific codon of mRNA

52.

After translation is complete what happens?

a)

a protein contains the sequence of amino acids originally specified in the DNA

b)

a fatty acid contains the sequence of amino acids originally specified in the DNA

53.

Translation Initiation

a)

tRNAs move in with the appropriate amino acid, the amino acid chain grows

b)

mRNA attaches to the smaller subunit of the ribosome

c)

The larger subunit of the ribosome then joins

d)

AUG is the start codon- a tRNA with the appropriate anticodon (UAC) attaches

54.

Translation Elongation

a)

mRNA attaches to the smaller subunit of the ribosome

b)
  • AUG is the start codon- a tRNA with the appropriate anticodon (UAC) attaches

c)
  • The larger subunit of the ribosome then joins

d)

tRNAs move in with the appropriate amino acid, the amino acid chain grows

55.

Translation Termination

a)

1 of 3 STOP codons are reached

b)

tRNAs move in with the appropriate amino acid, the amino acid chain grows

c)

The amino acid chain is then processed

d)
  • The larger subunit of the ribosome then joins

e)

In eukaryotes, the amino acid chain moves into the endoplasmic reticulum to be further processed.

56.

tRNAs carrying the correct amino acid recognize the proper codons on the mRNA because

a)

the anticodon of the tRNA hydrogen binds to the codon of the mRNA by complementary base pairing

b)

the codon of the tRNA binds to the anticodon of the ribosome by complementary base pairing

c)

the amino acid binds to the anticodon of the mRNA and brings the correct tRNA with it

d)

the codon of the mRNA binds the correct amino acid, and the tRNA stabilizes this interaction

57.

The central dogma of molecular biology states that the information contained within genes flows in which direction?

a)

DNA to DNA to protein

b)

mRNA to DNA to protein

c)

DNA to mRNA to protein

d)

DNA to tRNA to mRNA to protein

58.

If an organism's DNA contains 20% adenine nucleotides, what percentage of its DNA is composed of guanine nucleotides?

a)

10%

b)

20%

c)

30%

d)

40%

59.

DNA replication is called semiconservative because

a)

one of the two resulting DNA molecules is new.

b)

the two resulting DNA molecules each have one new DNA strand and one old strand from the original DNA molecule

c)

both of the resulting DNA molecules are composed of new strands of nucleotides

d)

the sequence of nucleotides in one strand is conserved, whereas the new DNA molecule consists of a unique sequence of nucleotides

60.

Which base is found in DNA, but not in RNA?

a)

cytosine

b)

uracil

c)

thymine

d)

adenine

61.

If RNA polymerase malfunctions,

a)

one of the subunits of rRNA will not be transcribed from DNA.

b)

amino acids will not be joined to their tRNA.

c)

mRNA cannot bind to rRNA.

d)

an mRNA will not be formed.

62.

Which process requires the participation of all three types of RNA?

a)

Transcription

b)

Translation

c)

RNA processing

d)

replication

63.

The stages of translation are

a)

transcription, mRNA processing, and termination

b)

DNA replication, transcription, and termination

c)

initiation, transcription, elongation cycle, and termination

d)

initiation, elongation cycle, and termination

64.

DNA replication makes a(n) __________ copy of the DNA strand, while transcription makes a(n) _________ copy of the DNA strand.

a)

mRNA; DNA

b)

DNA;mRNA

c)

DNA;tRNA

d)

mRNA; tRNA

65.

Which of the following processes does not occur within the nucleus?

a)

DNA replication

b)

Transcription

c)

intron removal

d)

translation

66.

The sequence of the mRNA that would result from transcribing the DNA template stand TAC GCT AAT

a)

AUG CGA UUA

b)

AUU AGC GUA

c)

ATG CGA TTA

d)

UAA UCG CAU

67.

Which of the following events in gene expression control does not occur in the nucleus?

a)

chromatin condensation

b)

mRNA translation

c)

DNA transcription

d)

mRNA processing

68.

The protein derived from a particular gene is different when it is found in a neuron than in a muscle cell. This is most likely due to

a)

alternative mRNA processing.

b)

regulation of mRNA translation.

c)

alteration of protein activity.

d)

mRNA editing.

69.

An intervening sequenced of DNA that is not expressed is called a(n)

a)

intron

b)

exon

c)

gene

d)

promoter

70.

A silent mutation is more likely to occur as a result of

a)

a frameshift mutation.

b)

a point mutation that does not change the amino acid encoded within the gene.

c)

the movement of a transposon into an exon.

d)

a point mutation that alters the amino acid encoded within the gene.

71.

What is a frameshift mutation?

a)

insertion or deletion of nucleotide bases in numbers that are not multiples of three

b)

a mutation in which a single pair of nucleotides at a certain point in the gene sequence is altered.

c)

a type of mutation that involves the addition of one or more nucleotides into a segment of DNA.

d)

a type of genetic mutation that involves the removal of a portion of the genetic material

72.

What is a phenotype?

a)

the characterisitc version of a trait that we actually see

b)

the specific combination of "hereditary particles" carried by an individual that cause a phenotype

73.

Homozygote

a)

when both alleles for the same trait are in the same. Example PP or pp (true breeding)

b)

when alleles for the same trait differ. Example pp (non-true breeding)

74.

What is Homozygous Dominant (PP)?

a)

a genotype where an individual inherits two copies of a dominant gene

b)

carries two copies of a recessive gene

c)

having different alleles for a particular trait

75.

Homozygous Recessive (pp)

a)

a genotype where an individual inherits two copies of a dominant gene

b)

carries two copies of a recessive gene

c)

having different alleles for a particular trait

76.

Heterozygous (Pp)

a)

a genotype where an individual inherits two copies of a dominant gene

b)

carries two copies of a recessive gene

c)

having different alleles for a particular trait

77.

Locus

a)

place of interest on a chromosome, usually a gene

b)

place in the DNA strand that encodes information causing a trait

78.

Law of Segregation

a)

Each individual has two factors for each trait

b)

The factors segregate (separate) during the formation of the gametes

c)

Each gamete contains only one factor from each pair of factors

79.

Law of Independent Assortment

a)

the alleles of two (or more) different genes get sorted into gametes independently of one another

b)

each gamete contains only one factor from each pair of factors

c)

each pair of factors segregates (assorts) independently of the other pairs

d)

all possible combinations of factors can occur in the gametes

80.

What is the ratio of independent assortments

a)

9:3:3:1

b)

3:3:1:3

81.

Incomplete Dominance

a)

an inheritance pattern where two alleles blend to create a new phenotype.

b)

the alleles of two (or more) different genes get sorted into gametes independently of one another

82.

Sex-Linked Inheritance

a)

Females are XX

b)

Males are XY

c)

X is much large and carries more genes

83.

What is X-linked

a)

gene on X chromosome

b)

gene on Y chromosome

84.

What is an allele?

a)

alternative forms of a gene

b)

place in the DNA strand that encodes information causing a trait

85.

What is a carrier?

a)

a female who carries an X-linked trait but does not express it.

b)

a male who carries an X-linked trait but does not express it

86.

X-linked recessive disorder

a)

Sons inherit trait from mothers- son's X comes from mother

b)

more males than females have disorder- allele on X is always expressed in males

c)

Females who have the condition inherited the mutant allele from both their mother and their father

d)

Conditions appear to pass from grandfather to grandson

87.

What is pleiotropy?

a)

the phenomenon in which a single locus affects two or more apparently unrelated phenotypic traits

b)

codominance

88.

Skin Color is coded for by several different genes which results in a range of skin colors from very dark to very light. This is an example of

a)

polygenic inheritance

b)

pleiotropy

c)

codominance

d)

incomplete dominance

89.

Sickle-cell disease is caused by a single mutation in the DNA of a particular gene. A person with this disease has red blood cells that lose their original donut shape and form a sickle shape. People with this disorder suffer from low energy levels, blood clots, and strokes. This is an example of

a)

a multifactorial trait

b)

pleiotropy

c)

codominance

d)

incomplete dominance

90.

A couple has three children, two of which have blonde hair. The third child and both parents have dark hair. What can be determined about the gene for hair color in this family?

a)

Blonde hair color is an autosomal recessive trait

b)

Blonde hair color is an autosomal dominant trait

c)

Blonde hair color is a sex-linked dominant trait

d)

Blonde hair color is a sex-linked recessive trait.

91.

If both parents express a particular trait, but their child does not, what does this indicate about the trait?

a)

The trait is an autosomal dominant trait

b)

The trait is an autosomal recessive trait

c)

The trait is sex-linked dominant

d)

This is a lethal trait

92.

What is Multifactorial inheritance?

a)

when more than 1 factor causes a trait or health problem, such as a birth defect or chronic illness.

b)

a pattern of inheritance characteristic of some genetic disorders.

93.

What is Autosomal dominant?

a)

a pattern of inheritance characteristic of some genetic disorders

b)

when more than 1 factor causes a trait or health problem, such as a birth defect or chronic illness.

94.

Parents with the dominant phenotype cannot have offspring with the recessive phenotype.

a)

True, because the dominant gene must be passed down from each parent

b)

True, because at least one dominant gene will be passed down from each parent

c)

False, because one parent could carry the recessive allele

d)

False, because both parents could carry the recessive allele