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Genetics Final Review

Total questions: 114

Worksheet time: 57mins

Name
Class
Date
1.

Induced mutations

a)

result from exposure to mutagens, physical and chemical agents that cause changes in DNA (ionizing irradiation, ultraviolet light, certain chemicals)

b)

occur without a known cause due to inherent metabolic errors, errors during DNA replication or unknown agents in the environment.

2.

Spontaneous mutations

a)

result from exposure to mutagens, physical and chemical agents that cause changes in DNA (ionizing irradiation, ultraviolet light, certain chemicals)

b)

occur without a known cause due to inherent metabolic errors, errors during DNA replication or unknown agents in the environment.

3.

Somatic mutations

a)

in somatic cells; the mutant phenotype will occur only in the descendants of that cell and will not be transmitted to the offspring (cause of many cancers in humans)

b)

in germ-line cells; will be transmitted through the gametes to the progeny

4.

Germinal mutations

a)

in somatic cells; the mutant phenotype will occur only in the descendants of that cell and will not be transmitted to the offspring (cause of many cancers in humans)

b)

in germ-line cells; will be transmitted through the gametes to the progeny

5.

Point mutations

a)

changes at specific sites in a gene (caused through substitution, insertion, or deletion)

b)

insertions or deletions of one or two base pairs alter the reading fram of the gene distal to the site of mutation.

6.

Frameshift mutations

a)

changes at specific sites in a gene (caused through substitution, insertion, or deletion)

b)

insertions or deletions of one or two base pairs alter the reading fram of the gene distal to the site of mutation.

7.

What causes mutations?

a)

errors in DNA replication or from the damaging effects of mutagens, such as chemicals and radiation

b)

Chemicals that are mutagenic to both replicating and nonreplicating DNA (e.g., alkylating agents and nitrous acid); Chemicals that are mutagenic only to replicating DNA (e.g., base analogs and acridine dyes)

8.

Types of chemical mutagens

a)

errors in DNA replication or from the damaging effects of mutagens, such as chemicals and radiation

b)

Chemicals that are mutagenic to both replicating and nonreplicating DNA (e.g., alkylating agents and nitrous acid); Chemicals that are mutagenic only to replicating DNA (e.g., base analogs and acridine dyes)

9.

What do all amino acids have in common?  

a)

the same basic structure; each molecule has a central carbon atom linked together with a basic amino group, a carboxylic acid group, a hydrogen atom and an R-group, or side-chain group

b)

long chain of amino acids

10.

What is a polypeptide?

a)

the same basic structure; each molecule has a central carbon atom linked together with a basic amino group, a carboxylic acid group, a hydrogen atom and an R-group, or side-chain group

b)

long chain of amino acids

11.

What determines the structure and function of a protein?

a)

the function is determined through the structure; structure of a protein is determined through the sequence of amino acids in the primary structure

b)

composed of nucleotide triplets; contains start and stop codons; nonoverlapping; degenerate (redundant); not ambiguous; nearly universal

12.

Why did people favor amino acids/proteins over nucleotide bases/DNA as the carrier of information?

a)

their structural diversity and complexity derived from their composition of 20 different amino acids, as opposed to DNA's 4 nucleotide bases

b)

set of three nucleotides (codons) that have the instructions to make a specific amino acid (or to start or stop the making of the polypeptide chain)

13.

What is meant with ‘triplet code’?

a)

their structural diversity and complexity derived from their composition of 20 different amino acids, as opposed to DNA's 4 nucleotide bases

b)

set of three nucleotides (codons) that have the instructions to make a specific amino acid (or to start or stop the making of the polypeptide chain)

14.

What is a reading frame?

a)

The beginning of the coding sequence

b)

means all events before the formation of a peptide bond between the first two amino acids

15.

What is initiation?

a)

The beginning of the coding sequence

b)

means all events before the formation of a peptide bond between the first two amino acids

16.

What is termination?

a)

occurs when a chain-termination codon (stop codon) enters the A site of the ribosome; A water molecule is added to the carboxyl terminus of the nascent polypeptide

b)

transcription and translation

17.

What are the steps of protein synthesis?

a)

occurs when a chain-termination codon (stop codon) enters the A site of the ribosome; A water molecule is added to the carboxyl terminus of the nascent polypeptide

b)

transcription and translation

18.

What are aminoacyl-tRNAs?

a)

matches the right amino acid with the right tRNA (with the corresponding anti- codon); According to the genetic code, there are 64 different tRNA

b)

Workbench: machines and tools to make a polypeptide; 50% protein, 50% RNA

19.

What are ribosomes?

a)

matches the right amino acid with the right tRNA (with the corresponding anti- codon); According to the genetic code, there are 64 different tRNA

b)

Workbench: machines and tools to make a polypeptide; 50% protein, 50% RNA

20.

How are bacterial and eukaryotic ribosomes different from each other?

a)

In prokaryotes: ribosomes are distributed throughout the cell; In eukaryotes: in the cytoplasm and/or attached to endomembrane system

b)

During initiation, the ribosomes attach at a specific site of the mRNA, The ribosome starts matching tRNA anticodon sequences to the mRNA codon sequence; during termination, ribosome continues until it hits a stop sequence, then it releases the polypeptide and the mRNA

21.

How is protein synthesis initiated and terminated?

a)

In prokaryotes: ribosomes are distributed throughout the cell; In eukaryotes: in the cytoplasm and/or attached to endomembrane system

b)

During initiation, the ribosomes attach at a specific site of the mRNA, The ribosome starts matching tRNA anticodon sequences to the mRNA codon sequence; during termination, ribosome continues until it hits a stop sequence, then it releases the polypeptide and the mRNA

22.

The purpose of meiosis is to:

a)

produce diploid gametes

b)

produce clonal cells

c)

produce haploid gametes

d)

produce a haploid zygote

e)

divide the chromosome number by a third

23.

Mendel proposed that each individual organism (i.e. pea plants) carried how many alleles, or copies of a gene?

a)

1

b)

2

c)

3

d)

4

e)

5

24.

The process that leads to development haploid gamete is best described as ________.

a)

segregation

b)

independent assortment

c)

Mendelian inheritance

d)

replication

e)

dominance or recessiveness

25.

Which if the following is not a source of genetic variation in meiosis?

a)

crossing over

b)

law of independent assortment

c)

the random lining up of chromosomes on the metaphase plate

d)

tetrad formation

e)

polar body formation

26.

The central point that connects the two rod-like portions of the chromosome is known as:

a)

Centrosome

b)

Centromere

c)

Central element

d)

Central spindle

e)

Connecting element

27.

At the end of meiosis, each of the four daughter cells, which will be involved in sexual reproduction, will exist in a _________ state.

a)

Haploid

b)

Diploid

c)

Triploid

d)

Polyploid

e)

None of these

28.

Prior to mitosis, each chromosome of an eukaryotic cell consists of a pair of identical structures called

a)

chromatin.

b)

sister chromosomes.

c)

nucleoli.

d)

sister chromatids.

29.

Two chromosomes in a nucleus that carry genes controlling the same inherited characteristics are

a)

homologous chromosomes.

b)

heterologous chromosomes.

c)

complementary chromosomes.

d)

parallel chromosomes.

30.

What is the final product of mitosis?

a)

sperm and egg cells

b)

two daughter cells identical to the parent cell

c)

4 daughter cells identical to the parent

d)

2 daughter cells not identical to the parent cell

e)

3 brother cells

31.

How many different combinations of maternal and paternal chromosomes can be packaged in gametes made by an organism with a diploid number of 8 (2n = 8)?

a)

2

b)

4

c)

8

d)

16

e)

32

32.

Two plants are crossed, resulting in offspring with a 3:1 ratio for a particular trait. What does this suggest?

a)

that the parents were true-breeding for contrasting traits

b)

that the trait shows incomplete dominance

c)

that a blending of traits has occurred

d)

that the parents were both heterozygous for a single trait

e)

that each offspring has the same alleles for each of two traits

33.

The principle of dominance states that:

a)

In a heterozygote, one allele can never conceal the presence of another allele.

b)

In a heterozygote, one allele may conceal the presence of another allele.

c)

In a homozygote, one allele may never conceal the presence of another allele.

d)

In a homozygote, one allele may conceal the presence of another allele.

e)

None of these

34.

According to Mendel's model, because of the ________ of chromosomes during meiosis, all possible combinations of gametes will be formed in equal frequency.

a)
  1. independent assortment

b)

chromosomal theory of inheritance

c)
  1. law of unit factors

d)
  1. the product rule

e)
  1. law of segregation

35.

In the cross AaBbCc × AaBbCc, what is the probability of producing the genotype AABBCC?

a)

1/4

b)

1/8

c)

1/16

d)

1/32

e)

1/64

36.

Which of the following calculations require that you utilize the addition rule (sum rule)?

a)

Calculate the probability of black offspring from the cross AaBb × AaBb, when B is the symbol for black.

b)

Calculate the probability of children with both cystic fibrosis and polydactyly when parents are each heterozygous for both genes.

c)

Calculate the probability of each of four children having cystic fibrosis if the parents are both heterozygous.

d)

Calculate the probability of a child having either sickle-cell anemia or cystic fibrosis if parents are each heterozygous for both

37.

Bob and Sue are both heterozygote for the recessive allele which causes cystic fibrosis. Their first child is homozygote recessive and therefore shows the affected phenotype. The couple seeks the help of a genetic counselor on future family planning. They would like to know what their chances are for having an unaffected second child, especially considering that they already have one affected child. The genetic counselor will tell them....

a)

The chances for having a second child with the disorder are increased because of the first child having the disorder

b)

The chances for having a second child with the disorder are decreased because of the first child having the disorder

c)

The condition of the first child has no influence on the chances for having a second affected

child, because each birth is an independent event.

38.

An organism that inherits two different alleles for a single trait, one from its mother and one from its father is known as a(n):

a)

Homozygote

b)

Homo sapiens

c)

Heterozygote

d)

Allelic variation

e)

Blended individual

39.

The house fly, Musca domestica, has a haploid chromosome number of 6. How many chromatids should be present in a diploid, somatic, metaphase cell?

a)

3

b)

6

c)

12

d)

18

e)

24

40.

Which of the following is true about the second meiotic division?

a)

Sister chromatids are pulling apart.

b)

Homologous chromosomes are pulling apart.

c)

Nondisjunction would lead to extra bivalents forming.

d)

Synapsis occurring in the second meiotic division.

e)

The products are four identical gametes.

41.

The definition of a dominant allele is:

a)

an allele that is the most common in a given population individuals with dominant personalities

b)

the latent allele in a heterozygous individual

c)

the expressed factor in the heterozygote

d)

the allele that causes disease

e)

both c and d

42.

Which of the following is an example of codominance?

a)
  1. a certain plant can have jagged, rough, or smooth edges on its leaves

b)
  1. flowers of a certain plant can come in purple, blue, or yellow

c)
  1. a scorpion's venom is more potent when it's younger

d)
  1.  there are many possible mutations that lead to white eyes in flies

e)
  1. in roan cattle, you can see a mix of both red and white furs

43.

A sexually reproducing animal has two unlinked genes, one for head shape (H) and one for tail length (T). Its genotype is HhTt. Which of the following is possible in a gamete from this organism?

a)

tt

b)

Hh

c)

HhTt

d)

T

e)

HT

44.

In tomatoes, red fruit color is dominant (Y) and yellow is recessive (y). A red-fruited plant, when crossed with a yellow-fruited plant, produces offspring about half of which are yellow- fruited and half of which are red-fruited. What are the genotypes of the parents?

a)

YY and yy

b)

Yy and yy

c)

Yy and Yy

d)

yy and yy

45.

A mutation in a gene often results in a reduction of the product of that gene. The term for this type of mutation is ________.

a)

codominance

b)

incomplete dominance

c)

gain of function

d)

multiple allelism

e)

loss of function or null (in the case of complete loss)

46.

The trait of medium-sized leaves in iris is determined by the genetic condition PP′. Plants with large leaves are PP, whereas plants with small leaves are P′P′. A cross is made between two plants each with medium-sized leaves. What is the term for this allelic relationship?

a)

incomplete dominance

b)

codominance

c)

multiple alleles

d)

epistasis

e)

positional effect

47.

A ________ ratio indicates incomplete dominance.

a)

1:1:1:1

b)

1:2:1

c)

9:7

d)

3:1

e)

2:2:2

48.

Which of the following best describes the relationship at the molecular level between mutant alleles and phenotype?

a)

a mutant allele will cause the wild-type protein not to be made.

b)

a mutant allele can have different effects depending on the gene product's function.

c)

The wild-type allele is always dominant.

d)

Mutant alleles will only cause problems when seen in the homozygous form, no matter the gene affected.

e)

A mutant allele will cause only one phenotype.

49.

Albinism, lack of pigmentation in humans, results from an autosomal recessive gene. Two parents with normal pigmentation have an albino child. What is the probability that their next child will be albino? (In other words: What is the probability for the scenario of having two kids, both albino?)

a)

1/4

b)

1/3

c)

1/2

d)

3/4

e)

1/16

50.

A recessive allele in dogs causes white spots. If two solid colored dogs are mated and produce a spotted offspring, what is the percentage chance their next puppy would be solid colored?

a)

25%

b)

50%

c)

about 66%

d)

75%

e)

about 90%

51.

Mendel decides he wants to save some time and do one large experiment. He sets up a self-cross of a plant with the genotype Tt Rr Yy Pp Ii Gg Aa. How many squares would you need to make a Punnett square large enough to account for all of the potential offspring?

a)

256

b)

1024

c)

16384

d)

65536

52.

In cats, there is a gene which causes additional toes. Cats which have this gene always have additional toes, but the number of additional toes varies. This is an example for

a)

expressivity

b)

penetrance

c)

dominance

d)

sex-linked inheritance

53.

The presence of more than two alternative forms of a given gene would be called ________.

a)

multiple alleles

b)

alternation of generations

c)

codominance

d)

incomplete dominance

e)

hemizygosity

54.

The phenomenon of a gene which has multiple phenotypic effects on an individual is referred to as ________.

a)

continuous variation

b)

pleiotropy

c)

expressivity

d)

penetrance

e)

epistasis

55.

A trait exhibited in one sex but not the other is referred to as ________.

a)

sex-influenced

b)

sex-linked

c)

sex-limited

d)

genomic imprinting

56.

90% of children that inherit a mutated retinoblastoma gene develop the disease. This represents an example of ________.

a)

penetrance

b)

expressivity

c)

pleiotropy

d)

a conditional mutation

e)

genetic imprinting

57.

Which of the following terms refers to a situation where a single phenotypic character (like skin color) is determined by the additive effects of two or more genes?

a)

incomplete dominance

b)

codominance

c)

pleiotropy

d)

polygenic inheritance

58.

A ________ is one whose expression is influenced by some environmental condition.

a)

X-linked allele

b)

conditional mutant

c)

positional effect

d)

multiple allele

e)

expressive allele

59.

Which region(s) of the X chromosome can recombine during meiosis?

a)

the pseudoautosomal regions

b)

the heterochromain

c)

the centromere

d)

the male-specific region of the Y

e)

SRY

60.

Sex-linked conditions are more common in men than in women because

a)

men acquire two copies of the defective gene during fertilization.

b)

men need to inherit only one copy of the recessive allele for the condition to be fully expressed.

c)

the sex chromosomes are more active in men than in women.

d)

the genes associated with the sex-linked conditions are linked to the Y chromosome, which determines maleness.

61.

In mammals, dosage compensation for X-linked genes is achieved by:

a)

Hyperactivation of X-linked genes

b)

Down regulation of X-linked genes

c)

Inactivation of one X-chromosome during early development

d)

All of these

e)

None of these

62.

An X chromosome that has been inactivated becomes a(an)___________ in female mammals.

a)

Barr body

b)

Oncogene

c)

Bacteriophage

d)

All of these

e)

None of these

63.

Among different species, sex may be determined by

a)

differences in sex chromosomes

b)

differences in the number of of sets of chromosomes

c)

environmental factors

d)

all of the above

64.

A white-eyed Drosophila female (white/white) is crossed with a red-eyed male. Assuming the trait for eye color is sex-linked, what are the possible phenotypes of the progeny? (red eyes is the wildtype allele and dominant to white eyes).

a)

All red-eyed individuals

b)

Red- and white-eyed females and males

c)

Red-eyed females and white-eyed males

d)

Red- and white-eyed males and only-white eyed females

e)

None of these

65.

A color blind male marries a woman who has normal vision. The woman has no history of colorblindness in her family. What percentages of their sons are expected to be colorblind?

a)

25%

b)

50%

c)

75%

d)

100%

e)

0%

66.

Assume that a man who carries an X-linked gene has children. Assuming normal meiosis and random combination of gametes, the man would pass this gene to ________.

a)

half of his daughters

b)

all of his daughters

c)

all of his sons

d)

half of his sons

e)

all of his children

67.

Which of the following is the part of the Y chromosome that is critical for normal male development?

a)

SRY

b)

Pseudoautosomal region

c)

Centromere

d)

All of these

e)

None of these

68.

An individual with two kinds of gametes (i.e. X bearing and Y bearing) is referred to as:

a)

Homogametic

b)

Heterogametic

c)

Heterozygous

d)

None of these

e)

All of these

69.

Suppose you cross a female cat with orange fur and a male cat with black fur, giving you a litter of kittens that are heterozygous for fur coat color. Which of the following best describes the phenotypes you expect to observe in the offspring?

a)

Male kittens will be orange and female kittens will be tortoiseshell.

b)

Male kittens will be black, and female kittens will be orange.

c)

Male and female kittens will all be tortoiseshell.

d)

Male kittens will be black or orange, and female kittens will be tortoiseshell.

e)

Male kittens will be tortoiseshell and female kittens will be orange or black.

70.

Which of the following is required to unambiguously link a gene to a chromosome?

a)

The gene must be defined by a mutant allele

b)

The chromosome must be morphologically distinguishable

c)

The pattern of gene transmission must reflect the chromosome's behavior during reproduction.

d)

All of these

e)

None of these

71.

The centimorgan (cM) is a unit named in honor of Thomas Hunt Morgan. To what is it equal?

a)

the physical distance between two linked genes

b)

1% frequency of recombination between two genes

c)

1 nanometer of distance between two genes

d)

the distance between a pair of homologous chromosomes

e)

the recombination frequency between two genes assorting independently

72.

You conduct a dihybrid cross. A ________ ratio would make you suspect that the genes are linked.

a)

3:1

b)

1:1:1:1

c)

12:1:1:4

d)

9:3:3:1

73.

A frequency of recombination that is less than 50% implies:

a)

The genes are linked on the same chromosome

b)

The genes are linked on different chromosomes

c)

The genes are not linked and are on different chromosomes

d)

The genes assort independently

e)

The genes are not linked and are on the same chromosome

74.

A ________ is all the genes on a single chromosome.

a)

linkage group

b)

recombination group

c)

chromosomal conglomeration

d)

genetic allele formation

e)

gene loci line

75.

What is a physical map of a chromosome?

a)

description of the base pair difference between two loci

b)

determination of where the centromere lies

c)

determination of how far apart genes are by recombination mapping

76.

Which of the following most accurately represents how “Hot Dog” Sturtevant created the first chromosome map?

a)

He used a microscope to view the genes

b)

He used a set of microcalipers to measure the distance between the genes on the chromosome

c)

He used the data he retrieved from experimental crosses to determine the distance between the genes on the chromosome

d)

All of these

e)

None of these

77.

Which of the following is a true statement?

a)

Genes that are on the same chromosome should be inherited together

b)

Genes that are on the same chromosome proceed through meiosis together

c)

Genes that are on different chromosomes are not linked

d)

All of these are true

e)

None of these are true

78.

Cytoplasmic or extranuclear inheritance occurs due to

a)

chromosomes that have detached from the spindle apparatus during meiosis

b)

genetic material that is found not in the nucleus but in chloroplasts and mitochondria

c)

mutations that disrupt the integrity of the nuclear membrane

d)

none of the above

79.

In a three-point mapping experiment (means there are 3 linked genes under consideration), how many different genotypic classes are expected?

a)

0

b)

1

c)

2

d)

4

e)

8

80.

The genetic map distance between two loci is roughly equal to

a)

The estimated number of crossovers that occur between two points

b)

The recombination frequency written as a percentage

c)

The non-recombination frequency written as a percentage

d)

The number of parental phenoytpes seen in the progeny

e)

None of these

81.

In a three-point cross, the double crossover classes can be used to identify

a)

the chi-square value

b)

the nonrecombinant phenotype

c)

gene distance

d)

gene linkage

e)

the gene in the middle

82.

A pictorial chart of chromosomes arranged from largest to smallest is known as a(an):

a)

Karyotype

b)

Genetic analysis

c)

Pedigree chart

d)

Amniocentesis

e)

Chorionic villus sample

83.

Which of the following can cause a phenotypic change in an organism?

a)

Too many chromosomes

b)

Too few chromosomes

c)

Changes in part of a chromosome

d)

Too many chromosomes and too few chromosomes

e)

All of these

84.

Having a complete set or sets of chromosomes is called ________.

a)

euploid

b)

monoploid

c)

ploidy

d)

diploid

e)

aneuploidy

85.

The most common cause for trisomy events in human beings is:

a)

Normal disjunction during meiosis

b)

Non-disjunction during meiosis

c)

Normal disjunction during oogenesis

d)

Normal disjunction during spermatogenesis

e)

None of these is a cause for trisomy

86.

Why are many polyploids sterile?

a)

Extra sets of chromosomes segregate irregularly in meiosis leading to aneuploidic gametes

b)

Extra sets of chromosomes segregate regularly in meiosis leading to aneuploidic gametes

c)

Extra sets of chromosomes segregate irregularly in mitosis leading to aneuploidic gametes

d)

All of these

e)

None of these

87.

Although the most frequent forms of Down syndrome are caused by a random error, nondisjunction of chromosome 21, Down syndrome occasionally runs in families. The cause of this form of familial Down syndrome is ________.

a)

an inversion involving chromosome 21

b)

a chromosomal aberration involving chromosome 1

c)

too many X chromosomes

d)

a translocation between chromosome 21 and another chromosome

e)

a maternal age effect

88.

The chromosomal aberration that causes cri-du-chat syndrome can be referred to as a(n) ________.

a)

duplication

b)

inversion

c)

reciprocal translocation

d)

simple translocation

e)

segmental deletion

89.

What is explained by a major population genetics theory?

1. The number of individuals in a population

2. The allelic frequencies within a population

3. The number of individuals outside a population

a)

1

b)

2

c)

3

d)

1 and 2

e)

All of these

90.

Which of the following best expresses the concept of natural selection?

a)

differential reproductive success based on inherited characteristics

b)

inheritance of acquired characteristics

c)

change in response to need

d)

a process of constant improvement, leading eventually to perfection

91.

A population is

a)

a group of individuals of the same species that live in the same area and interbreed.

b)

all individuals of a species, regardless of location or time period in which they live.

c)

a group of individuals of different species living in the same place at the same time.

d)

a group of individuals of a species plus all of the other species with which they interact.

92.

Which of the following accurately describes the Hardy-Weinberg equation?

a)

P2 + 2p +q2

b)

P2 + 2pq + q3

c)

P2+2pq+q2

d)

P3 + 3pq+q3

93.

The frequency of homozygous dominant individuals in a population that is in Hardy-Weinberg equilibrium is equal to

a)

q or p

b)

p2

c)

2pq

d)

2p

94.

Which of the following terms represents the frequency of heterozygotes in a population that is in Hardy-Weinberg equilibrium?

a)

p

b)

q

c)

2pq

d)

q2

95.

The recessive allele of a gene causes cystic fibrosis. For this gene among Caucasians, frequency p (a) = 0.98. If a Caucasian population is in Hardy-Weinberg equilibrium with respect to this gene, what proportions of babies are born homozygous recessive, and therefore suffer from cystic fibrosis?

a)

0.022 = 0.0004

b)

0.02

c)

0.982 = 0.9604

d)

2(0.02 × 0.98) = 0.0392

96.

Thirty people are selected for a long-term mission to colonize a planet many light years away from Earth. The mission is successful and the population rapidly grows to several hundred individuals. However, certain genetic diseases are unusually common in this group, and their gene pool is quite different from that of the Earth population they have left behind. Which of the following phenomena has left its mark on this population?

a)

founder effect

b)

bottleneck effect

c)

high rates of mutation

d)

natural selection

97.

Imagine that you are studying a very large population of moths that is isolated from gene flow. A single gene controls wing color. Half of the moths have white-spotted wings (genotype WW or Ww) and half of the moths have plain brown wings (ww). There are no new mutations, individuals mate randomly, and there is no natural selection on wing color. How will p, the frequency of the dominant allele, change over time?

a)

p will increase; the dominant allele will eventually take over and become most common in the population.

b)

p will neither increase nor decrease; it will remain more or less constant under the conditions described.

c)

p will decrease because of genetic drift

d)

p will fluctuate rapidly and randomly because of genetic drift

98.

What is a form of recombination in bacteria that involves the F plasmid?

a)

conjugation

b)

transduction

c)

transformation

d)

adaptation

e)

fluctuation

99.

When mapping genes in bacteria, which of the following is true about the interrupted mating technique?

a)

Time of contact is not applicable to this protocol.

b)

Donor will pass only beneficial genes to the recipient.

c)

Genes will be passed from the centromere.

d)

Genes are transferred from the donor to recipient in a linear fashion based upon time of contact.

e)

The recipient bacterium will choose the best genes.

100.

Bacteria that are in a particular physiological state to become transformed are called

a)

episomal

b)

resistant

c)

temperate

d)

competent

e)

transformable

101.

Which large organic molecules are essential chromosome components?

a)

Lipids and proteins

b)

Proteins and nucleic acids

c)

Nucleic acids and polysaccharides

d)

Proteins and polysaccharides

102.

In Sia and Dawson's 1931 experiment,

a)

Mice were required to demonstrate the transforming principle

b)

Used serum to precipitate IIIS cells from a mixture of heat-killed IIIS and living IIR cells

c)

They showed that the mouse hosts play no direct role in the transforming principle

d)

Heat-killed IIR cells mixed with living IIIS cells gave rise to IIR colonies

e)

None of these

103.

Whose experiments provided direct evidence indicating that DNA, rather than RNA or protein, is the genetic material in bacteriophages?

a)

Griffith

b)

Avery, McLeod, and McCarty

c)

Hershey and Chase

d)

Watson and Crick

e)

Sia and Dawson

104.

What kind of data on DNA structure was gathered by Rosalind Franklin and Maurice Wilkins?

a)

3D model

b)

Base composition data

c)

X-ray diffraction pattern data

d)

All of these

e)

None of these

105.

Chromatin is defined as ________.

a)

DNA complexed with protein

b)

hybrid molecules of DNA and RNA

c)

genetic material found only in mitochondria

d)

a catalytic molecule with a protein component and an RNA component     

e)

supercoiled loops of bacterial DNA

106.

The functions associated with telomeres are to:

a)

Prevent ribonucleases from degrading the ends of linear RNA primer molecules

b)

Allow the fusion of broken chromosomal ends

c)

Facilitate replication of chromosomes without the loss of the chromosome’s arms tips

d)

Ensure the appropriate segregation of chromosomes

e)

Provide chromosomal anchorage to spindle-fibers

107.

The basic structure of a nucleotide includes ________.

a)

amino acids

b)

tryptophan and leucine

c)

base, sugar, and phosphate

d)

mRNA, rRNA, and tRNA

e)

phosphorus and sulfur

108.

Meselson and Stahl are best known for demonstrating that:

a)

DNA replication occurs in a conservative manner in E. coli

b)

DNA replication occurs in a semi-conservative manner in E. coli

c)

DNA replication occurs in a conservative manner in eukaryotes

d)

DNA replication occurs in a semi-conservative manner in eukaryotes

e)

None of these

109.

Which of the following enzymes catalyzes DNA synthesis?

a)

DNA ligase

b)

DNA helicase

c)

DNA polymerase

d)

DNA gyrase

e)

None of these

110.

The activity of ________ would be quickly undone in the absence of single-stranded binding protein.

a)

DNA polymerase I

b)

DNA polymerase III

c)

primase

d)

DNA ligase

e)

DNA helicase

111.

What is the basis for the difference in how the leading and lagging strands of DNA molecules are synthesized?

a)

The origins of replication occur only at the 5' end.

b)

Helicases and single-strand binding proteins work at the 5' end.

c)

DNA polymerase can join new nucleotides only to the 3' end of a growing strand.

d)

DNA ligase works only in the 3' → 5' direction

e)

Polymerase can work on only one strand at a time.

112.

Explain the technique of electrophoretic separation of DNA fragments

a)

A mixture of different sized DNA molecules are subjected to an electric field, and then to a magnetic field. The fragments migrate through a liquid matrix such that smaller fragments travel further in the matrix.

b)

A mixture of different sized DNA molecules are subjected to an electric field, and then to a magnetic field. The fragments migrate through a semisolid matrix such that larger fragments travel further in the matrix.

c)

A mixture of different sized DNA molecules are subjected to an electric field, and migrate through a semisolid matrix such that smaller fragments travel further in the matrix.

d)

A mixture of different sized DNA molecules are subjected to an electric field, and migrate through a solid matrix such that larger fragments travel further in the matrix.

113.

Which process transfers information from DNA to RNA?

a)

Replication

b)

Transcription

c)

Translation

d)

Splicing

e)

None of these

114.

Prokaryotic and eukaryotic RNA's differ in that:

a)

rRNA molecules are only subunits of the prokaryotic ribosome

b)

Eukaryotes have a pre-mRNA that requires splicing to create the functional transcript

c)

Prokaryotes have non-coding sequences that are removed during RNA-transcript processing

d)

Eukaryotes have simpler ribosomes, consisting of fewer subunits.

e)

None of these