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Overview of DNA structure, history and replication

Total questions: 29

Worksheet time: 2hrs 25mins

Name
Class
Date
1.

Created models of DNA

a)

Chargaff

b)

Franklin

c)

Watson and Crick

d)

Hershey and Chase

2.

Used x-rays to take pictures of DNA

a)

Chargaff

b)

Franklin

c)

Watson and Crick

d)

Hershey and Chase

3.

Figured out the amount of A, T, G, and C that many different organisms have

a)

Chargaff

b)

Franklin

c)

Watson and Crick

d)

Hershey and Chase

4.

Created radioactive viruses to see what their genetic material was made of

a)

Mendel

b)

Griffith

c)

Avery

d)

Hershey and Chase

5.

Known as the "Father of Genetics"

a)

Mendel

b)

Griffith

c)

Avery

d)

Hershey and Chase

6.

Alone, R-bacteria caused pneumonia. (refer to Griffith's experiments--p.413)

a)

true

b)

false

7.

What is the backbone of this DNA molecule made of?

a)

sugars

b)

nitrogen bases

c)

sugar and phosphate

d)

sugar and nitrogen bases

8.

Rosanlind Franklin's x-ray diffraction image of her study of DNA was noticed by Watson and Crick and led them to model what they thought the shape and structure of DNA was. What was the structure?

a)

the double helix

b)

the single strand

c)

the sugar and phosphate

d)

the four nitrogen bases

9.

Erwin Chargaff's rule of base pairing states that:

a)

adenine pairs with thymine and guanine pairs with cytosine

b)

adenine pairs with guanine and thymine pairs with cytosine

c)

purines pair with pyrimidines

d)

pyrimidines pair only with pyrimidines

10.
If the original sequence is CGA TTA AGC, what would be the complementary nucleotides added during DNA replication?
a)
GCU AAU UCG
b)
GCT AAT TCG
c)
ATC GGC CTA
d)
CGA ATT AGC
11.

DNA replication produces ___ molecules of DNA.

a)

2 Identical

b)

2 Different

c)

4 Identical

d)

4 Different

12.
The process of DNA replication occurs in which organelle?
a)
Cytoplasm
b)
Ribosome
c)
Nucleus
d)
Mitochondria
13.
By using radioactive isotopes, Hershey and Chase were able to conclude that __ is/are the carrier(s) of genetic information.
a)
DNA
b)
Proteins
c)
Carbohydrates
d)
Lipids
14.
The work of scientists including Griffin, Avery, Hershey & Chase and Franklin helped us to determine the __ are responsible for carrying genetic material.
a)
Amino Acids
b)
Proteins
c)
Nucleic Acids
d)
Carbohydrates
15.

Who developed the general model of DNA that we use today?

a)

Rosiland Franklin

b)

Watson & Crick

c)

Eli Whitney

d)

Robert Oppenheimer

16.

Who took X-Ray Crystallography images of DNA that helped to determine its shape and size?

a)

Rosiland Franklin

b)

Watson & Crick

c)

Eli Whitney

d)

Robert Oppenheimer

17.

Replication is the process by which

a)

DNA makes copies of itself

b)

RNA makes copies of itself

c)

DNA makes proteins

d)

The Borg reproduce

18.

Which of the following is a correct base pair in DNA?

a)

A-G

b)

A-C

c)

C-T

d)

T-A

e)

G-T

19.

Check all of the below that are Nitrogen Bases in DNA.

a)

Adenine

b)

Guanine

c)

Cytosine

d)

Thymine

e)

Thimosine

20.

The function of DNA is to provide instructions for making proteins and thus run your body.

a)

True

b)

False

21.
Who is responsible for producing this image?
a)
Francis Crick
b)
James Watson
c)
Rosalind Franklin
d)
Watson and Crick
22.
What does this image show?
a)
Double helical structure of DNA
b)
Triple Helical Structure of DNA
c)
Double helical structure of RNA
d)
Triple Helical Structure of RNA
23.
How did Rosalind Franklin's photo 51 affect the work of Watson and Crick?
a)
It was used to determine the physical structure of DNA
b)
It was used to identify the four bases that make up DNA
c)
It was used to determine the theory of independent assortment
d)
It was used to show DNA was the molecule of inheritance
24.
What did Erwin Chargaff conclude from his experiments?
a)
Nitrogen bases are held together by peptide bonds
b)
A and T, C and G always occur in equal amounts
c)
Proteins are the carriers of genetic information
d)
C and G rarely occur in eukaryotic organisms
25.
What was Watson and Crick's main scientific accomplishment?
a)
Building the first accurate model of DNA
b)
Isolating strains of pneumonia causing bacteria
c)
Determining base pairing rules
d)
Discovering the process of genetic transformation
26.
From his work with mice and pneumonia-causing bacteria, Frederick Griffith discovered what?
a)
Replication
b)
Transcription
c)
Transformation
d)
Translation
27.
By using radioactive isotopes, Hershey and Chase were able to conclude that _____ is the carrier of genetic information.
a)
DNA
b)
Protein
c)
Carbohydrate
d)
Lipid
28.
The work of Erwin Chargaff allowed Watson and Crick to determine the rules of.......
a)
protein synthesis
b)
transcription
c)
hydrogen bonding
d)
nitrogen base pairing
29.
Who was responsible for the model shown?
a)
Oswald Avery
b)
Watson and Crick
c)
Erwin Chargaff
d)
Rosalind Franklin