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WorksheetsOssification
Total questions: 41
Worksheet time: 21mins
What is the central cavity found within the shaft of long bones called?
Epiphysis
Articular cartilage
Medullary cavity
Spongy bone
Which part of the long bone is responsible for the production of red blood cells, white blood cells, and platelets?
Articular cartilage
Diaphysis
Medullary cavity
Epiphysis
What is the term for the dense outer surface of bone that forms a protective layer around the internal cavity?
Spongy bone
Diaphysis
Epiphysis
Articular cartilage
Where is the articular cartilage located in a long bone?
At the ends of the epiphysis
Inside the medullary cavity
Along the diaphysis
Within the spongy bone
What is the skeleton of a very young animal predominantly made of?
Bone
Cartilage
Muscle
Tendon
What happens to the cartilage in an animal's skeleton as it grows?
It decreases and is replaced by muscle.
It remains unchanged throughout the animal's life.
It increases and converts to bone.
It decreases and is replaced by tendon.
What does the prefix "OSTEO" in the names of bone cells signify?
It signifies strength and durability.
It is derived from the Greek word for bone.
It indicates the cellular structure.
It refers to the osteoporosis condition.
What are OSTEOCLASTS?
Cells that build up bone tissue.
Cells that are found in the blood.
Large cells that dissolve the bone.
Small cells that protect the bone.
Where do osteoclasts originate from?
The heart
The liver
The bone marrow
The brain
How many nuclei do osteoclasts usually have?
One
Two
More than one
None
Where are osteoclasts usually found?
Throughout the bone marrow
On the surface of the bone mineral next to the dissolving bone
Inside the bone matrix
In the bloodstream
What are osteoblasts?
Cells that break down bone
Cells that form new bone
Cells that form new muscle tissue
Cells that are found in the blood
Where do osteoblasts originate from?
The liver
The bone marrow
The heart
The skin
What is the substance called that is produced by osteoblasts to form new bone?
Osteoclast
Osteoid
Marrow
Cartilage
What do osteoblasts become when they have finished filling in a cavity?
They die off
They become lining cells
They transform into osteoclasts
They detach from the bone
What is the role of lining cells derived from osteoblasts?
To regulate the passage of calcium into and out of the bone
To produce new muscle fibers
To generate new blood cells
To absorb bone tissue
What are osteocytes?
Cells outside the bone that dissolve the bone
Cells inside the bone that come from osteoblasts
Cells in the blood that create new bone
Cells that are completely isolated inside the bone
What is the role of osteocytes in the bone?
They dissolve the bone without direction
They are isolated and do not interact with other cells
They send out long branches to connect to other osteocytes and can direct where osteoclasts will dissolve the bone
They form the outer layer of the bone and protect it from damage
What is the function of an osteocyte?
Forms bone matrix
Resorbs bone
Maintains bone tissue
Is a stem cell
Which cell is responsible for forming the bone matrix?
Osteocyte
Osteoclast
Osteoblast
Osteogenic cell
What is the role of an osteoclast in bone tissue?
Maintains bone tissue
Forms bone matrix
Is a stem cell
Resorbs bone
What is the precursor cell that can differentiate into other bone cells?
Osteocyte
Osteoblast
Osteoclast
Osteogenic cell
Which of the following processes are involved in bone development?
Intramembranous ossification
Endochondral ossification
Osteoclastic activity
Marrow cavity formation
Which parts of the skeleton are formed by intramembranous ossification?
Skull and clavicle
Rest of skeleton
Femur and tibia
Pelvis and vertebrae
Which parts of the skeleton are formed by endochondral ossification?
Skull and clavicle
Most of axial and appendicular skeleton
Hands and feet only
Ribs and sternum only
What is intramembranous ossification?
The process where bone is formed from cartilage.
The process where bone is laid down to replace fibrous connective tissue.
The process where bone is broken down into fibrous connective tissue.
The process where bone is replaced by cartilaginous tissue.
In which development does intramembranous ossification occur?
The development of the long bones of the limbs.
The development of the bones of the skull, maxilla, and mandible.
The development of the vertebral column.
The development of the bones of the rib cage.
What is initially replaced by osteocytes and calcium hydroxyapatite in endochondral ossification?
Bone marrow
Hyaline cartilage
Muscle tissue
Adipose tissue
Where do primary ossification centres appear during endochondral ossification?
In the epiphyses of bones
In the diaphysis of bones
In the periosteum of bones
In the endosteum of bones
Where do secondary ossification centres appear during endochondral ossification?
In the diaphysis of bones
In the periosteum of bones
At the ends (epiphyses) of bones
In the bone marrow
What is the first step in the process of endochondral ossification?
Osteoblasts replace cartilage with bone
The outline structure of the bone is formed first of cartilage
Primary ossification centres appear in the diaphysis of bones
Secondary ossification centres appear at the ends (epiphyses) of bones
What is the role of the epiphyseal growth plate in bone development?
It produces new bone cells directly.
It produces new cartilage cells that elongate the bone.
It ossifies the cartilage cells into bone cells.
It remodels the interior of the diaphysis.
How are the cartilage cells on the side of the epiphyseal growth plate nearest the diaphysis converted?
They are remodeled by osteoclasts.
They are ossified by osteoblasts.
They are elongated by the growth plate.
They are replaced by new cartilage cells.
What happens to the bone once it has reached its final length?
The cartilage cells continue to divide indefinitely.
The medullary cavity stops expanding.
The cartilage cells stop dividing and all cartilage is ossified.
Osteoclasts continue to remodel the bone.
What is the first stage of endochondral ossification?
Osteoclasts begin creating marrow cavity.
Secondary ossification begins in epiphysis.
Primary ossification begins in diaphysis.
Cartilage model exists in embryo.
Where does the primary ossification begin during endochondral ossification?
In the epiphysis.
In the marrow cavity.
In the diaphysis.
In the growth plate.
During endochondral ossification, when does the secondary ossification begin?
After the growth plate fuses.
When the marrow cavity extends.
In the diaphysis.
In the epiphysis.
What happens to the growth plate during the final stage of endochondral ossification?
It begins to form.
It remains open.
It fuses and growth ceases.
It is replaced by marrow.
What is the name of the region in a growing long bone where growth occurs?
Diaphysis
Metaphysis
Epiphyseal plate (growth plate)
Epiphysis
What replaces the epiphyseal plate in a mature long bone?
Epiphyseal line
Metaphysis
Diaphysis
Epiphysis
What is the term for the main shaft of a long bone?
Epiphyseal line
Metaphysis
Epiphyseal plate
Diaphysis
