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HHB 3.6 Specific Cellular Defences against Pathogens

Total questions: 25

Worksheet time: 23mins

Name
Class
Date
1.

Which of the following is an example of a specific immune defence?

a)
phagocytosis
b)
lymphocytes secreting antibodies
c)
inflammatory response
d)
stomach acid
2.

Which term is used to describe molecules, often proteins located on the surface of cells that trigger a specific immune response?

a)
antigen
b)
antibody
3.

What type of white blood cells are involved in the specific immune response and respond to specific antigens on invading pathogens?

a)

lymphocytes

b)

phagocytes

c)

mast cells

d)

antibodies

4.

What term describes Y-shaped proteins that have receptor binding sites specific to a particular antigen on a pathogen?

a)

antibodies

b)

cytokines

c)

lysosomes

d)

histamine

5.

What term describes the clones of identical lymphocytes are produced when a lymphocyte is activated by binding to a specific antigen?

a)
cloning
b)
clonal population
c)
inflammatory response
d)
doubling population
6.
Which of the following would stimulate clonal population formation by lymphocytes?
a)
the presence of different lymphocytes
b)
the binding of antigens to receptors on the cell membrane of a lymphocyte
c)
the presence of phagocytes
d)
the binding of antibodies to receptors on the cell membrane of a lymphocyte
7.
Which type of blood cells carry out a specific immune response?
a)
Phagocyte and B Lymphocytes
b)
B Lymphocytes & T Lymphocytes
c)
Phagocytes and T Lymphocytes
d)
Phagocytes & Mast Cells
8.
An autoimmune disorder results when...
a)
B lymphocytes respond to self-antigens
b)
T lymphocytes respond to a harmless antigen
c)
T lymphocytes respond to self-antigens
d)
B lymphocytes respond to a harmless antigen
9.

Which of the following are examples of autoimmune diseases?

a)

type 1 diabetes and rheumatoid arthritis.

b)

type 2 diabetes and rheumatoid arthritis.

c)

type 1 diabetes and stroke

d)

heart attack and rheumatoid arthritis.

10.
What term describes the programmed cell death of a cell?
a)
apoptosis
b)
inflammatory response
c)

clonal selection

d)

differentiation

11.

Which type of cells destroy infected body cells by recognising antigens of the pathogen on the cell membrane and inducing programmed cell death?

a)

T lymphocytes

b)

B lymphocytes

12.
An allergic response occurs when?
a)
B lymphocytes respond to a harmless antigen
b)
T lymphocytes respond to a harmless antigen
c)
T lymphocytes respond to self antigens
d)
B lymphocytes respond to self antigens
13.
Which of these is present on the surface of pathogens?
a)
self-antigens
b)
non self-antigens
14.

Which of these is present on the surface of your own body cells?

a)
self-antigens
b)
non self-antigens
15.

T lymphocytes attach onto infected cells and release proteins. These proteins diffuse into the infected cells causing production of _____________ which cause cell death.

a)

self-destructive enzymes

b)

cytokines

c)

histamine

d)

antibodies

16.

Antibodies become bound to antigens, inactivating the pathogen. The resulting antigen-antibody complex can then be destroyed by what process?

a)

phagocytosis

b)

desensitisation

c)

summation

d)

allergic reaction

17.

An allergic reaction is caused by the hypersensitive response of ______________ to a harmless substance.

a)
B lymphocytes
b)
T lymphocytes
c)
Mast cells
d)
Phagocytes
18.
Which type of immune cell can produce antibodies?
a)
B lymphocyte
b)
Phagocyte
c)
Mast Cell
d)
Epithelial cell
19.

In which immune response is antibody production is greater and more rapid?

a)
primary response
b)
secondary response
20.
What name is given to a group of genetically identical lymphocyte cells?
a)
B lymphocytes
b)
Clonal population
c)
Mast cells
d)
antibodies
21.
What type of immune cell is attacked and destroyed by the HIV virus?
a)
B lymphocytes
b)
T lymphocytes
c)
Phagocytes
d)
Mast cells
22.
What type of immune response will target a particular pathogen?
a)
non-specific response
b)
specific response
23.
What name is given to some of the cloned B & T lymphocytes that survive long term in the body?
a)
memory cells
b)

antibodies

c)
mast cells
d)
white blood cells
24.

An antigen binding to a lymphocyte leads to repeated lymphocyte division, resulting in the formation of a ______________ of identical lymphocytes.

a)

clonal population

b)

cytokine population

c)

antigen-antibody complex

d)

clonal apoptosis

25.

___ causes depletion of T lymphocytes which leads to the development of AIDS (acquired immune deficiency syndrome).

a)

HIV

b)

DNA

c)

RNA

d)

ATP