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WorksheetsPatho Exam 2
Total questions: 74
Worksheet time: 38mins
A patient has a tissue growth that was diagnosed as cancer. Which of the following terms best describes this growth?
Neoplasm
Meningioma
Lipoma
Hypertrophy
A nurse discusses preinvasive epithelial tumors of glandular or squamous cell origin. What is the nurse describing?
Tumor in differentiation
Dysplastic
Cancer in situ
Cancer beyond (meta) situ
What is a gene that codes for normal protein used in cell division?
Oncogene
Proto-oncogene
Tumor necrosis factor
Papilloma
A 30-year-old female is diagnosed with cancer. Testing reveals that the cancer cells have spread to local lymph nodes. A nurse realizes this cancer would be documented as stage:
1
2
3
4
An immunologist is discussing endotoxin production. Which information should the immunologist include?
Gram-negative bacteria
Gram-positive bacteria
Gram-negative fungi
Gram-positive fungi
When the immunologist says that pathogens possess virulence, what does virulence mean?
The ability to cause disease
The ability to reproduce
The ability to survive in harsh conditions
The ability to mutate rapidly
Which organ is stimulated during the general adaptation syndrome (GAS) alarm phase?
adrenal cortex
hypothalamus
anterior pituitary
limbic system
Perceived stress elicits an emotional, anticipatory response that begins where?
prefrontal cortex
anterior pituitary
limbic system
Hypothalamus
The hallmark of infectious diseases is
Fever
Swelling
Pain
Redness
The most common route for metastasis is through lymphatic tissue and...
Cells
Mitochondria
Neurons
Blood vessels
SATA- What are the symptoms in all forms of diabetes Mellitus?
Polydipsia
Polyuria
Vomiting
Polyphagia
BMI is determined by looking at ..
Height and weight
Weight and age
Age and ethnicity
Age and gender
Most common cause of death with a cancer patient
Cancer cachexia
Infection
Lethargy
Emesis
A cold has an abrupt onset of symptoms compared to the flu?
True
False
Helicobacter pylori causes most
UTIs
Peptic and duodenal ulcers
Strep
The flu
How do bacteria fight back against antibiotics? SATA:
Inactivate antibiotics
Change antibiotic binding sites
Use different metabolic pathways
Change their walls to keep antibiotics out
A 5-year-old male becomes ill with a severe cough. Histologic examination reveals a bacterial infection, and further laboratory testing reveals cell membrane damage and decreased protein synthesis to the cells of his mucus membrane. Which of the following is the most likely cause of this illness?
Endotoxin
Exotoxin
Hemolysis
Septicemia
The Epstein-Barr Virus is associated with mononucleosis.
True
False
Allostatic overload is described as the body’s way of using its resources to adapt to the stressor.
True
False
Carcinoma is described as..
Malignant tumor of epithelial tissue
Benign tumor of glandular tissue
The enzyme that drives the cell cycle
None of the above
Parenchyma is described as..
Functional cells of a tissue
Cancer cells new blood supply
Insulin receptors
Obesity symptoms
Subcutaneous fat has higher leptin, lower adiponectin, lower inflammatory cytokines, and lower insulin resistance.
True
False
The progressive breakdown of compensatory mechanisms and homeostasis is associated with which stage of stress
Allostatic Overload
Stage of resistance
Stage of adaption
Stage of alarm
The islets of Langerhans are composed of beta cells that secrete glucagon, alpha cells that secrete insulin, and delta cells that secrete somatostatin into the blood
True
False
Appetite is controlled by...
Amygdala
Thalamus
The arcuate nucleus (ARC) of the hypothalamus
Anterior Pituitary gland
Obesity is a metabolic disorder with an increase in body fat mass and a body mass index (BMI) greater than 30
True
False
The exhaustion stage is characterized by all except
energy depletion
increased mean arterial blood pressure
degeneration of cells
loss of homeostasis
The major hormones or groups of hormones that are instrumental in the endocrine response to stress include: (SATA)
CRH
ACTH
Cortisol
Catecholamines
Tumor markers are molecules in blood, urine, or other fluids that indicate a change in the status of tumor growth
True
False
Penetration into lymphatics, blood vessels, or body cavities is what stage of cancer
Stage 1
Stage 2
Stage 3
Stage 4
Diabetic ketoacidosis (DKA) mainly occurs in
Type 1 patients
Type 2 patients
Diabetes Insipidus patients
HHS Syndrome patients
What glucose level is in the range to describe ketoacidosis?
110 mg/dL
95 mg/dL
260 mg/dL
180 mg/dL
What part of the cell browns adipose tissue?
The nucleus
Mitochondria
Lysosomes
Ribosomes
All are true about Leptin except:
Stimulate appetite
Levels increase after eating
Interacts with the mesolimbic dopamine system
Levels increase with the number of adipocytes
What defines malignant tumors?
Has a well-defined capsule
Low mitotic index
Grows slowly
Undifferentiated
(T or F) Oncogenes are normal genes responsible for the regulation of the proliferation of cells.
True
False
Obesity produces a state of low-grade chronic inflammation in...
Brown Adipose Tissue
Beige Fat
White Adipose Tissue
Muscle
(T or F) Anorexigenic neurons are appetite-stimulating (stimulate eating and decrease metabolism).
True
False
Characteristics of Cortisol (SATA)
Potent pro-inflammatory hormone
Part of a negative feedback loop
Increases metabolism
Increasing circulating glucose
Posterior Pituitary releases... (SATA)
ADH
Cortisol
Oxytocin
Diabetic nephropathy is a clinical syndrome characterized by all except:
Proteinuria
Hypotension
Edema
Renal insufficiency
The most common complication leading to hospitalization among people with diabetes:
Renal disease
Macrovascular complications
Foot ulcers
Polyuria
Cardiovascular disease is the ultimate cause of death in the majority of patients with diabetes.
True
False
The earliest manifestation of kidney dysfunction in a patient with diabetes is:
ketonuria
albuminuria
glycosuria
glucosuria
Criteria for Metabolic Syndrome include all except:
Increased waist circumference: Men > 40 inches; women > 35 inches
Decrease triglyceride levels: < 150 mg per dL
Elevated blood pressure: ≥ 130/85 mmHg
Elevated fasting glucose level: ≥ 100 mg per dL
Reduced high-density lipoprotein (HDL) cholesterol levels: Men < 40 mg/dL; women < 50 mg/dL
Paraneoplastic syndromes are manifestations of cancer that often result from:
Tumor-related tissue necrosis
Compression of area vessels
Altered hormonal activity
Radiation and chemotherapy
The stage when the host develops the signs and symptoms like a mild fever and body aches after exposure to an infectious agent is called:
Incubation
Prodromal
Acute
Convalescence
High-risk factors for the development of adult renal cell cancer include:
heavy smoking
adrenal medulla tumors.
inherited renal disease
anorexia/bulimia disorder
A tumor arises from the continued cell division of a single cancerous cell.
True
False
Telomeres continue to grow in size as you age and become older.
True
False
What is the potential effect of chronic hyperglycemia on pancreatic beta cells?
Increased insulin sensitivity
Beta-cell desensitization
Enhanced insulin production
Decreased glucose absorption
Stress can exacerbate any disease or condition.
True
False
Which of the following patients would be at greatest risk for basal cell carcinoma?
dark complexion, light eyes, underweight
light complexion, dark eyes, overweight
medium complexion, light eyes, smoker
light complexion, light eyes, fair hair
Malaria is caused by parasites that carry the bacteria Plasmodium.
True
False
The HPA axis is coordinated by a chain of hormones between the hypothalamus, pituitary, and adrenal glands. Which of the following are the correct hormones: SATA
CRF
ACTH
Cortisol
Epinephrine
Norepinephrine
What is a good description of a scirrhous tumor?
firm grapes in jello with threads in it
soft like grapes in Jello with threads in it
Rock-like bumps in jello with a clear coat
Thicker jello with threads in it
A middle-aged patient diagnosed with coronavirus disease 2019 presents with fever, fatigue, and mild cough. After initial antiviral treatment, the patient’s symptoms persist, and they are eventually diagnosed with viral pneumonia. Imaging shows ground-glass opacities in both lungs. All of the following occur early in the infection, EXCEPT: (SATA)
SARS-CoV-2 primarily targets T cells for initial infection
Alveolar epithelial type II cells are targeted by the virus
Pulmonary consolidation occurs due to alveolar epithelial-endothelial barrier disruption
The virus binds to the angiotensin-converting enzyme 2 (ACE2) receptor
Symptoms like fever and cough typically resolve within 48 hours of infection
SATA S/S of an inflammatory response of an inflammatory response:
Pain
Redness
Swollen
Temperature
SOB
SATA: What hormones are needed in the regulation of food-uptake?
Adiponectin
Cholecystokinin (CKK)
Leptin
Ghrelin
Insulin
The nurse is assessing a patient who was recently divorced and is now living in a temporary shelter after losing her home in a hurricane. Which finding indicates that the patient is experiencing allostatic load?
The patient is in a state of exhaustion.
The patient is using available resources to respond to stress.
The patient is making healthy lifestyle choices.
The patient is in an internal state of balance.
The plan of care for a woman newly diagnosed with a BRCA1 mutation should include which strategy?
Preoperative planning for immediate prophylactic double mastectomies
A recommendation for enhanced screening for breast and ovarian cancer
Reassurance that male offspring with BRCA1 do not develop breast cancer
Reassurance that the BRCA1 gene protects against ovarian cancer
When planning care for a trauma patient, which statement does the nurse understand best describes the body's response to stress?
The stress response suppresses the hypothalamic-pituitary-adrenal axis.
The stress response has a negative effect on the endogenous opioid pathway.
The stress response is the result of stimulation of the sympathetic nervous system.
The stress response boosts the adaptive immune response.
SATA: Bacteria develop resistance to antibiotics through which of the following mechanisms?
Altering the antibiotic binding sites
Producing enzymes that degrade antibiotics
Increasing the synthesis of the bacterial cell wall
Pumping antibiotics out of the cell
The nurse is caring for a client with herpes simplex virus. The nurse understands that chronic stress can cause which of the following conditions?
increased cell-mediated immunity
inactivation of the humoral immune response
reduction in the levels of circulating antibody for HSV
reactivation of the latent virus
The nurse is caring for a client with an infection. The nurse anticipates which of the following effects of chronic stress on this client?
a suppressed innate immune response
a heightened immune response
no effect on the immune system
an intensified adaptive immune response
A client in the stage of alarm would most likely exhibit which of the following?
exhaustion
organ damage
increased mean arterial blood pressure
bradycardia
True or false: Grading describes the spread of the tumor
True
False
Local effects of cancer include...SATA
Death of parenchyma
Compression of blood
Bleeding
Fatigue
The four top infections and new cancer cases include all except
HPV
H. Pylori
HCV
Pharyngitis
The most lethal skin cancer is what?
Melanoma
Carcinoma
Adenoma
Lymphoma
Persistent stress is followed by the resistance stage whereby cortisol levels decrease through positive feedback loops.
True
False
The stroma is important in cancer development because cancers actively recruit an immune and stromal response to assist in the remodeling of tissues, formation of new blood vessels, and promotion of metastasis.
True
False
Oncogenes
are mutated forms of tumor suppressor genes
are mutated genes the inhibit the cell cycle
are mutated forms of genes that code for proteins that normally assist in apoptosis
are mutated genes that code for proteins which activate cell division too often or at the improper time
Common treatments for cancer include:
CHOOSE ALL THAT APPLY!
chemotherapy
immunotherapy
radiation therapy
psychotherapy
multivitamins
