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ENTERIC BACTERIA PART 1

Total questions: 28

Worksheet time: 18mins

Name
Class
Date
1.

All Enterobacteriaceae are Cytochrome oxidase negative, except which genus?

(a)  

2.

This genus of enteric organisms are generally non-motile at 37C, but motile at room temperature.

(a)  

3.

Scientist who first described E. coli ( complete name)

(a)  

4.

Causative agent of “MONTEZUMA’S REVENGE” (acronym only)

(a)  

5.

The binding unit of this toxin binds with GM1 ganglioside receptor

a)

Verotoxin 1

b)

ETEC LT toxin

c)

EHEC ST toxin

6.

Binds to glomerular endothelium and inactivates von Willebrand factor-cleaving protease

a)

Verotoxin 1

b)

ETEC LT toxin

c)

EHEC ST toxin

7.

Pathologic condition characterized by microangiopathic hemolysis, severe thrombocytopenia and Kidney Failure.

(answer in full)

(a)  

8.

Results from the transformation of adenosine triphosphate (ATP) to cyclic adenosine monophosphate (cAMP).

a)

lysis of phagocytic vacuole and bacterial replication into the cell cytoplasm

b)

cessation of protein synthesis

c)

hypersecretion of fluids and electrolytes into the lumen of the intestines

9.

Binding site of Verotoxin 1 B subunit

a)

GM1 ganglioside receptor

b)

Globotriaosylceramide

c)

Translocated intimin receptor

10.

Causes loss of intestinal barrier function through disruption of tight junctions and induces host cell death through apoptosis.

a)

Translocated intimin receptor

b)

intimin

c)

Escherichia coli secreted protein F

11.

O157 : H7

a)

ETEC

b)

EIEC

c)

EPEC

d)

EHEC

e)

EAEC

12.

On which media could we initially identify EHEC?

a)

MAC

b)

EMB

c)

HEA

d)

BAP

13.

Mucus secretion and formation of a thick biofilm is characteristic of which E. coli strain?

(use acronym)

(a)  

14.

Which organism/s may also produce the green metallic sheen produced by E. coli on EMB?

a)

Klebsiella

b)

Citrobacter

c)

Enterobacter

d)

Salmonella

15.

Non-lactose fermenting Klebsiella

a)

K. rhinoscleromatis

b)

K. oyxtoca

c)

K. ozaenae

d)

K. pneumoniae subsp. pnuemoniae

16.

Indole (+) Klebsiella spp (use this format: E. coli)

(a)  

17.

Positive result for Moeller KCN Broth

a)

dissolution/ clear solution

b)

turbidity

c)

blackening

d)

formation of red color

18.

Antibiotic therapy disrupts the normal gut microbiota and promotes the overgrowth of Klebsiella oxytoca with subsequent production of cytotoxin called (a)   .

19.

Antibiotic-associated hemorrhagic colitis resolves spontaneously within 2-3 days when the offending antibiotics are discontinued.

a)

TRUE

b)

FALSE

20.

Causative agent of donovanosis (use format: E. coli

(a)  

21.

Fish-eye colonies are produced by which group (genus) of enteric organisms?

(a)  

22.

Caused a nationwide (U.S) outbreak of septicemia resulting from contaminated IV fluids

a)

Enterobacter cloacae

b)

Enterobacter agglomerans

c)

Enterobacter aerogenes

23.

Rarely isolated from blood cultures.

a)

Enterobacter cancerogenus

b)

Enterobacter hormaechei

c)

Enterobacter gergoviae

24.

Pink to red pigment of Serratia

(a)  

25.

To which of the following assays does Salmonella demonstrate a (+) result?

a)

KCN growth

b)

Lysine decarboxylation

c)

ONPG

26.

Only urease (+) Providencia species

a)

Providencia alcalifaciens

b)

Providencia heimbachae

c)

Providencia rettgeri

d)

Providencia stuartii

27.

When different Proteus species swarm towards each other, a line of inhibited growth results where strains meet. This is known as (a)  

28.

Most notable characteristic of Proteus colonies

a)

burnt chocolate odor

b)

swarming

c)

hemolysis