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Worksheetskassim Hafiz Hope MCQs on Transamination, Deamination, and Urea Cycle
Total questions: 20
Worksheet time: 48mins
Which of the following enzymes is primarily responsible for transamination reactions?
Glutamate dehydrogenase
aminotransferase
Hexokinase
Glutamine synthetase
What is the coenzyme required for transamination reactions?
NADH
FAD
Pyridoxal phosphate
Biotin
Which structure is shown above
Amino acid general structure
Urea
Guanidine
Serine
In transamination, an amino group is transferred from an amino acid to a:
α-keto acid
β-keto acid
Sugar molecule
Fatty acid
Transamination reactions are important for:
Gluconeogenesis
Glycogen synthesis
Amino acid catabolism
Fatty acid biosynthesis
What is transamination ?
The reaction of alanine and α-ketoglutarate in transamination produces which amino acid?
Glutamate
Aspartate
Glutamine
Alanine
Which of the following is NOT a product of a transamination reaction?
An amino acid
An α-keto acid
Glutamine
Glutamate
Which process is involved in the removal of an amino group from an amino acid?
Transamination
Deamination
Decarboxylation
Glycosylation
Which enzyme is primarily responsible for the oxidative deamination of glutamate?
Glutamine synthetase
Glutamate dehydrogenase
Aspartate aminotransferase
Alanine aminotransferase
Which molecule is produced during the deamination of glutamate?
Ammonia and pyruvate
Ammonia and α-ketoglutarate
Ammonia and oxaloacetate
Urea and aspartate
The ammonia produced in deamination is primarily converted into:
Uric acid
Urea
Creatinine
Ammonium chloride
What is the role of NAD+ in deamination reactions?
Acts as a coenzyme to transfer the amino group
Acts as hydrogen acceptor
Inhibits the enzyme action
Increases the solubility of ammonia
Which of the following is a common feature of both transamination and deamination?
Involvement of α-keto acids
Formation of ammonia
Generation of glucose
Involvement of ATP
Which of the following is the primary nitrogen excretion product in humans?
Urea
Ammonia
Uric acid
Creatine
In the urea cycle, carbamoyl phosphate is synthesized in which organelle?
Nucleus
Mitochondria
Cytoplasm
Ribosomes
Which enzyme catalyzes the conversion of ornithine to citrulline in the urea cycle?
Ornithine transcarbamylase
Arginase
Carbamoyl phosphate synthetase
Argininosuccinate synthase
How many steps are there in urea cycle?
4 steps
5 step
6 steps
7 steps
What enzyme catalyzes the conversion of ammonia and bicarbonate into carbamoyl phosphate in the mitochondria?
CPS-1
CPS-2
CPS-3
CPS-4
The urea cycle occurs in which two cellular compartments?
Nucleus and mitochondria
Cytoplasm and nucleus
Mitochondria and cytoplasm
Ribosomes and endoplasmic reticulum
