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kassim Hafiz Hope MCQs on Transamination, Deamination, and Urea Cycle

Total questions: 20

Worksheet time: 48mins

Name
Class
Date
1.

Which of the following enzymes is primarily responsible for transamination reactions?

a)

Glutamate dehydrogenase

b)

aminotransferase

c)

Hexokinase

d)

Glutamine synthetase

2.

What is the coenzyme required for transamination reactions?

a)

NADH

b)

FAD

c)

Pyridoxal phosphate

d)

Biotin

3.

Which structure is shown above

a)

Amino acid general structure

b)

Urea

c)

Guanidine

d)

Serine

4.

In transamination, an amino group is transferred from an amino acid to a:

a)

α-keto acid

b)

β-keto acid

c)

Sugar molecule

d)

Fatty acid

5.

Transamination reactions are important for:

a)

Gluconeogenesis

b)

Glycogen synthesis

c)

Amino acid catabolism

d)

Fatty acid biosynthesis

6.

What is transamination ?

4 lines
7.

The reaction of alanine and α-ketoglutarate in transamination produces which amino acid?

a)

Glutamate

b)

Aspartate

c)

Glutamine

d)

Alanine

8.

Which of the following is NOT a product of a transamination reaction?

a)

An amino acid

b)

An α-keto acid

c)

Glutamine

d)

Glutamate

9.

Which process is involved in the removal of an amino group from an amino acid?

a)

Transamination

b)

Deamination

c)

Decarboxylation

d)

Glycosylation

10.

Which enzyme is primarily responsible for the oxidative deamination of glutamate?

a)

Glutamine synthetase

b)

Glutamate dehydrogenase

c)

Aspartate aminotransferase

d)

Alanine aminotransferase

11.

Which molecule is produced during the deamination of glutamate?

a)

Ammonia and pyruvate

b)

Ammonia and α-ketoglutarate

c)

Ammonia and oxaloacetate

d)

Urea and aspartate

12.

The ammonia produced in deamination is primarily converted into:

a)

Uric acid

b)

Urea

c)

Creatinine

d)

Ammonium chloride

13.

What is the role of NAD+ in deamination reactions?

a)

Acts as a coenzyme to transfer the amino group

b)

Acts as hydrogen acceptor

c)

Inhibits the enzyme action

d)

Increases the solubility of ammonia

14.

Which of the following is a common feature of both transamination and deamination?

a)

Involvement of α-keto acids

b)

Formation of ammonia

c)

Generation of glucose

d)

Involvement of ATP

15.

Which of the following is the primary nitrogen excretion product in humans?

a)

Urea

b)

Ammonia

c)

Uric acid

d)

Creatine

16.

In the urea cycle, carbamoyl phosphate is synthesized in which organelle?

a)

Nucleus

b)

Mitochondria

c)

Cytoplasm

d)

Ribosomes

17.

Which enzyme catalyzes the conversion of ornithine to citrulline in the urea cycle?

a)

Ornithine transcarbamylase

b)

Arginase

c)

Carbamoyl phosphate synthetase

d)

Argininosuccinate synthase

18.

How many steps are there in urea cycle?

a)

4 steps

b)

5 step

c)

6 steps

d)

7 steps

19.

What enzyme catalyzes the conversion of ammonia and bicarbonate into carbamoyl phosphate in the mitochondria?

a)

CPS-1

b)

CPS-2

c)

CPS-3

d)

CPS-4

20.

The urea cycle occurs in which two cellular compartments?

a)

Nucleus and mitochondria

b)

Cytoplasm and nucleus

c)

Mitochondria and cytoplasm

d)

Ribosomes and endoplasmic reticulum