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WorksheetsApproach to Hemolytic Anemia Quiz
Total questions: 20
Worksheet time: 12mins
Investigation of choice for Paroxysmal Nocturnal Hemoglobinuria?
Ham test
Flow cytometry
Acidified glycerol test
Acidified serum test
Most probable diagnosis is?
Thalassemia major
Thalassemia minor
Sickle cell anemia
Immune hemolytic anemia
Hb Barts is composed of:
Four γ chains
Four β chains
Four alpha chains
Four ε chains
Identify the peripheral smear picture.
Sickle cell anemia
Beta Thalassemia minor
Microangiopathic hemolytic anemia
HbH disease
Autosplenectomy is seen in
Hereditary spherocytosis
Immune hemolytic anemia
Thalassemia
Sickle cell anemia
Most common mutation in Hereditary spherocytosis
Spectrin
Ankyrin
Band 3
Band 4.2
Intravascular hemolysis is predominant in
Hereditary spherocytosis
Thalassemia
Hereditary elliptocytosis
Hemolytic uremic syndrome
Features of hemolytic anemia are all except:
Increased bilirubin
Increased reticulocytes
Increased urobilinogen
Increased haptoglobin
Investigation of choice for Thalassemia?
Ham test
Bone marrow Aspiration
Hemoglobin electrophoresis
Acidified serum test
During Hematology class, Arnav learnt about G6PD deficiency and its effects on red blood cells. His facilitator mentioned various aspects of this condition. Which of the following statements about G6PD deficiency is false?
Episodic hemolysis
Young RBCs are more prone to hemolysis
Both intra & extravascular hemolysis
X linked recessive
A patient with ABO incompatibility will characteristically show the presence of following on peripheral smear:
Schistocytes
Elliptocytes
Target cells
Microspherocytes
Direct Coombs test detects:
Antigen on RBC surface
Antibody on RBC surface
Antigen in serum
Antibody in serum
Identify the renowned personality in this picture.
Robert Koch
Waldeyer
Mackenzie
Virchow
Hemoglobin synthesis starts in
Proerythroblasts
Early Normoblasts
Intermediate Normoblasts
Late Normoblasts
True about warm-antibody hemolytic anemia
Does not need complement
Active at 2-8 deg.celsius
IgM Antibody
CLL is an important cause
Supravital staining is used for?
Basophilic Normoblasts
Polychromatophilic Normoblasts
Orthochromic Normoblasts
Polychromatophilic Erythrocytes
A correct diagnosis is three-fourths the remedy
Mahatma Gandhi
Jawaharlal Nehru
Sardar Vallabhai Patel
Thiruvalluvar
A 42-year-old, previously healthy man from the tropics passes dark urine 2 days after having an anti-malarial drug. On examination: afebrile, pallor present, no hepatosplenomegaly. CBC: WBC Count: 7600 cells/mm³ RBC count: 3.8 million cells/mm³ Hb: 10.5 g/dl MCV: 78 fL, MCH: 25 pg, RDW: 14.6%, Platelet count: lakhs/mm³. What could be the probable diagnosis?
Paroxysmal Nocturnal Hemoglobinuria
Sickle cell anemia
G6PD deficiency anemia
Thalassemia
A 3-year-old boy from the Mediterranean is underweight for his age and height. On physical examination, there is severe pallor & hepatosplenomegaly. History of repeated blood transfusions. A radiograph of the skull shows maxillofacial deformities and expanded marrow spaces. CBC reveals: WBC Count: 12,280 cells/mm³; RBC count: 2.3 million cells/mm³; Hb: 5.4 g/dl; MCV: 51 fL; MCH: 16 pg; MCHC: 31 g/dl; RDW: 17.4% Platelet count: 4.75 lakhs/mm³. What is the diagnosis?
Thalassemia major
Sickle cell anemia
Hereditary spherocytosis
Thalassemia minor
A 15-year-old boy has a sudden onset of severe abdominal pain accompanied by fever, cough & chest pain. On physical examination, his temperature is 39.3°C, PR is 116/min, respirations are 22/min, and BP is 80/50 mm Hg. He has diffuse abdominal tenderness but no organomegaly. RBC has an abnormal shape on microscopy. CBC revealed WBC Count: 14,850 cells/mm³; RBC Count: 3.27 million cells/mm³; Hb: 9.2 g/dl; MCV: 85 fL; MCH: 27 pg; RDW: 15.7%; Platelet count: 3.2 lakhs/mm³
What is the most probable cause of this illness?
Thalassemia major
Hereditary spherocytosis
Thalassemia minor
Sickle cell anemia
