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Patho: Bacteria part 2, slide 42

Total questions: 93

Worksheet time: 1hrs 28mins

Name
Class
Date
1.

What are the 5 major genera of gram + rods (bacilli)?

a)

bacillus

b)

clostridium

c)

cornyebacterium

d)

listeria

e)

gardnerella

2.

Which bacilli bacteria is the only one with anaerobic growth?

a)

bacillus

b)

clostridium

c)

cornyebacterium

d)

listeria

e)

gardnerella

3.

Which two bacilli bacteria form spores?

a)

bacillus

b)

clostridium

c)

cornyebacterium

d)

listeria

e)

gardnerella

4.

Bacillus cereus:

Large or small? ​ (a)   with ​ (b)   ends.

​ (c)   form spores.

Mobility: ​ (d)  

Choose from the below words
Large rods
blunt
sharp
small rods
Can
Cannot
motile with flagella
non-motile
5.

Bacillus cereus is a ___ pathogen.

a)

opportunistic

b)

primary

6.

Bacillus cereus:

Hemolysis: ​ (a)  

metabolism: ​ (b)  

Catalase ​ (c)  

Oxidase ​ (d)  

Choose from the below words
B-hemolytic
facultative anaerobe
aerobic
a-hemolytic
(+)
(-)
7.

Bacillus cereus causes...

a)

gastroenteritis (food poisoning)

b)

ocular infections

8.

Bacillus cereus produces 2 enterotoxins:

a)

emetic toxin

b)

diarrheal toxin

9.

Bacillus cereus enterotoxins:

heat stable ​ (a)  

heat labile​ (b)  

Causes "fried rice syndrome" ​ (c)  

Choose from the below words
emetic toxin
diarrheal toxin
10.

Which gram + bacillus bacteria causes "fried rice syndrome"?

a)

Clostridium perfringens

b)

Bacillus cereus

c)

Clostridium difficile

11.

Clostridium perfringens:

Gram ​ (a)  

Shape: ​ (b)  

Metabolism: ​ (c)  

Mobility: ​ (d)  

Spores: ​ (e)  

Choose from the below words
(+)
bacilli
coccus
obligate anaerobe
facultative anaerobe
aerobic
non-motile
motile with flagella
spore forming
non-spore forming
12.

Clostridium perfringens is a microbiota found in....

a)

human respiratory tract

b)

GI tract of humans

c)

GI tract of animals

13.

Clostridium perfringens is....

a)

a-hemolytic

b)

B-hemolytic

c)

y-hemolytic

14.

Clostridium perfringens is spread by....

a)

vehicles (contaminated food)

b)

fecal-oral transmission

15.

What are virulence factors produced by clostridium perfringens?

a)

Enzymes

b)

cytotoxin

c)

enterotoxin

d)

fermentation products

16.

What enzymes are made by Clostridium perfringens?

a)

collagenase

b)

protease

c)

hyaluronidase

17.

Virulence factors of Clostridium perfringens:

Collagenase, proteases, hyaluronidase​ (a)  

Damages intestinal cells ​ (b)  

Can cause food poisoning​ (c)  

Cause build up of acids and gas causing tissue necrosis and gas gangrene of muscle tissue​ (d)  

1

Choose from the below words
enzymes
Cytotoxin
Enterotoxin
Fermentation
18.

Clostridium difficile:

Metabolism: ​ (a)  

Spores: ​ (b)  

Mobility: ​ (c)  

gram​ (d)  

Shape: ​ (e)  

Choose from the below words
obligate anaerobe
aerobe
spore forming
non-spore forming
mobile
(+)
rods (bacilli)
19.

Clostridium difficile is an opportunistic pathogen of the....

a)

respiratory tract

b)

GU tract

c)

GI tract

d)

skin

20.

Use of broad-spectrium antibiotics can give what gram + bacillus bacteria an advantage to colonize the gut?

a)

C. perfringens

b)

C. difficile

c)

Bacillus cereus

21.

Which is a more severe infection of Clostridium difficile?

a)

C. diff-associated diarrhea (CDAD)

b)

Pseudomembranous colitis (PMC)

22.

Clostridium difficile can cause a severe complication that results in extreme dilation of the colon due to inflammation that can lead to toxicity and shock. What is this phenomenon called?

a)

CDAD

b)

PMC

c)

Toxic megacolon

23.

What are the 2 enterotoxins produced by Clostridium difficile?

a)

Toxin A

b)

Toxin B

24.

Clostridium difficile:

Excessive fluid secretion ​ (a)  

Causes enterocyte death and inflammation ​ (b)  

enterotoxin ​ (c)  

Cytotoxin ​ (d)  

Choose from the below words
Toxin A
Toxin B
25.

Toxins from clostridium difficile are used for identification by ___ in fecal samples.

a)

ELISA

b)

not this

26.

Listeria monocytogenes:

Shape: ​ (a)  

Size: ​ (b)  

Mobility: ​ (c)  

Catalase ​ (d)  

Gram ​ (e)  

Choose from the below words
bacillus (rod)
small bacillus
tumbling motility
(+)
27.

Listeria monocytogenes is ___ hemolytic.

a)

a-hemolytic

b)

B-hemolytic

c)

y-hemolytic

28.

Lysteria monocytogenes is ___

a)

aerobic

b)

facultative anaerobe

c)

obligate anaerobe

29.

Listeria survives...

a)

proteolytic enzymes

b)

stomach acid

c)

bile salts

d)

salt tolerant

e)

cold tolerant at freezing temps

30.

Listeria causes....

a)

listeriosis (foodborne illness)

b)

meningitis

31.

Listeria infections are more common in ___

a)

sexually active females

b)

elderly

c)

pregnant females

d)

neonates

e)

IC individuals

32.

Listeria ​ (a)   cross the placenta. Also known as ​ (b)  

Choose from the below words
can
vertical transmission
cannot
33.

Listeria is a ___

a)

small bacilli

b)

large bacilli

34.

Listeria is a/an ​ (a)   anaerobic, ​ (b)   pathogen

Choose from the below words
Facultative
intracellular
obligate
extracellular
35.

Listeria adheres to enterocytes by Listeria adhesion proteins ___ and ___

a)

Internalin A

b)

Internalin B

36.

How does Listeria move from cell to cell?

a)

multiplies in the cytosol

b)

moves to cell membrane

c)

manipulates host actin cytoskeleton

d)

uses cytoskeleton to propel itself into other cells

1)
2)
3)
4)
37.

Listeria ​ (a)   survive phagocytosis.

Choose from the below words
can
cannot
38.

Corynebacterium diphtheriae:

Shape: ​ (a)  

Size: ​ (b)  

Motility: ​ (c)  

Oxygen: ​ (d)  

Choose from the below words
bacilli (club shaped)
small bacilli
non-motile
facultative anaerobes
cocci
large bacilli
motile
aerobic
39.

Cornebacterium diphtheriae is transmitted by ...

a)

respiratory drops

b)

direct contact with skin ulcers

c)

fomites

40.

Cornebacterium diphtheriae causes what 2 diseases?

a)

diphtheria (upper resp disease)

b)

SSTI (causes grey membrane covered skin ulcers)

41.

Corynebacterium diphtheriae releases ​ (a)   which is an ​ (b)   that is a potent inhibitor of host ​ (c)  

Choose from the below words
diphtheria toxin
exotoxin
protein synthesis
42.

What vaccine is given to prevent infection of Corynebacterium diphtheriae?

a)

DTaP

b)

Tdap

43.

Nocardia:

Gram ​ (a)  

Shape: ​ (b)  

Other stains: ​ (c)  

Features: ​ (d)  

Choose from the below words
+
bacilli
partially acid fast
filamentous rods
44.

Select all that is true of the gram + bacilli bacterium, Nocardia

a)

filamentous

b)

rod shaped

c)

sometimes confused as fungi (resembles mold)

d)

contains mycolic acid

e)

partially acid fast

45.

Nocardia:

Oxygen: ​ (a)  

catalase ​ (b)  

SOD ​ (c)  

Growth rate: ​ (d)  

Choose from the below words
obligate aerobic
+
slow growing
-
fast growing
facultative anaerobe
46.

Nocardia is a/an​ (a)   pathogen in IC patients that affects ​ (b)  

Choose from the below words
opportunistic
lungs, skin, and brain
47.

Inhaling Nocardia leads to ...

a)

pulmonary disease

b)

bronchitis

c)

pneumonia

d)

lung abscesses

48.

Nocardia, a gram + bacilli bacteria, ​ can ​ (a)   and ​ (b)   in macrophages by blocking the acidification of the lysosome.

Choose from the below words
survive
replicate
49.

Which gram + bacillus bacteria can survive inside of macrophage lysosomes by blocking the lysosome's acidification?

a)

Listeria

b)

Corynebacterium diphtheriae

c)

Nocardia

50.

Neisseria:

Gram ​ (a)  

Shape: ​ (b)  

Oxygen: ​ (c)  

Oxidase: ​ (d)  

catalase ​ (e)  

Choose from the below words
-
cocci
obligate aerobe
+
51.

What are the pathogenic forms of the gram - cocci bacterium, Neisseria?

a)

Neisseria meningitides

b)

Neisseria gonorrhoeae

52.

What are the virulence factors of the Gram - cocci, Neisseria?

a)

lipooligosaccharide (LOS, endotoxin)

b)

antigen variation

c)

encapsulated

d)

IgA proteases

e)

covered in pili to allow for adhesion

53.

Which form of the gram - cocci bacterium, Neisseria colonizes asymptomatic carriers (reservoirs) in the nasopharynx.

a)

N. gonorrhoeae

b)

N. meningitides

54.

Select all that is true of Neisseria.

a)

gram -

b)

cocci shaped

c)

diplococci

d)

coffee been appearance

55.

What vaccine is used to protect against Neisseria meningitides?

a)

meningococcal vaccine

b)

TDaP

c)

pneumunococcal

56.

the gram - cocci bacteria N. gonorrhoeae has​ (a)   transmission by direct ​ (b)   . It also has ​ (c)   transmission during childbirth that leads to ​ (d)  

Choose from the below words
horizontal
sexual contact
vertical
neonatal conjunctivitis
57.

When testing for N. gonorrhoeae, ​ (a)   in dishcarge are examined by microscopy for intraccellular ​ (b)  

Choose from the below words
Neutrophils
gram - diplococci
58.

Moraxella catarrhalis:

Gram ​ (a)  

Shape: ​ (b)  

Oxidase: ​ (c)  

Catalase: ​ (d)  

Motility​ (e)  

Choose from the below words
-
coccobacilli
+
non-motile
motile
bacilli
59.

Moraxella catarrhalis contain ___ for adherence.

a)

fimbriae

b)

flagella

c)

pilli

60.

Moraxella catarrhalis is a part of the microbiota of the ___

a)

GI tract

b)

upper resp tract

c)

GU tract

d)

skin

61.

What are the virulence factors for the gram - coccibacilli bacterium, Moraxella catarrhalis?

a)

LPS-endotoxin

b)

produces B-lactamases (inactivates B-lac antibiotics)

c)

produces neuraminidase (degrades mucin allowing for colonization of resp tract)

62.

Moraxella catarrhalis causes...

a)

bronchial infections

b)

otitis media in children

c)

seen in daycares and households

63.

Haemophilus influenzae:

Gram​ (a)  

shape: ​ (b)  

Enteric or non-enteric​ (c)  

Oxygen: ​ (d)  

oxidase ​ (e)  

catalase +

Choose from the below words
-
coccobacilli
non-enteric
facultative anaerobes
+
64.

Haemophilus influenzae requires ___ agar

a)

mannitol salt

b)

high salt

c)

chocolate

65.

H. influenzae can be invasive or noninvasive:

pneumonia, meningitis, epiglottitis, and cellulitis ​ (a)  

sinusitis, otitis media, and conjunctivitis ​ (b)  

Choose from the below words
invasive disease
non-invasive disease
66.

There ​ (a)   a vaccine for H. influenzae.

Choose from the below words
is
is not
67.

Aeromonas species:

Gram ​ (a)  

Shape: ​ (b)  

Oxygen: ​ (c)  

Can ferment ​ (d)  

Catalase ​ (e)  

oxidase +

Choose from the below words
-
bacilli
facultative anaerobes
lactose
+
68.

Where is Aeromonas found?

a)

fresh water

b)

brackish water

c)

soil

69.

What diseases does Aeromonas cause?

a)

diarrheal disease in health people

b)

wound infections and UTIs in IC pts

70.

What are the virulence factors of Aeromonas?

a)

flagella

b)

adhesins (flagella or pili)

c)

hemolysins

d)

siderophores

e)

endotoxins, enterotoxins, MDR, shiga-like toxin

71.

What are the 3 Aeromonas bacteria?

a)

A. hydrophila

b)

A. caviae

c)

A. veronii

72.

Vibrio:

Gram ​ (a)  

Shape ​ (b)  

Motility: ​ (c)  

Oxidase ​ (d)  

Ferments ​ (e)  

Choose from the below words
-
bacilli
motile, flagellum
+
lactose
73.

What Vibrio pathogen causes cholerae?

a)

Vibrio cholerae

b)

not this

74.

What toxin does vibrio cholerae produce?

a)

cholera toxin

b)

not this

75.

Vibrio cholerae toxins:

Cholera toxin:

toxin that binds to the GI epithelial cells ​ (a)  

Toxin that enters cells to increase cAMP levels leading to electrolyte imbalance and fluid secretion ​ (b)  

Choose from the below words
B part
A part
76.

E. coli:

Gram ​ (a)  

shape: ​ (b)  

Oxygen: ​ (c)  

oxidase ​ (d)  

catalase ​ (e)  

Choose from the below words
-
bacilli
facultative anaerobe
+
77.

E. coli ferments ___

a)

glucose

b)

lactose

78.

When E. coli ferments glucose and lactose, what are the products?

a)

lactic acid

b)

coliform gas

79.

Lactose fermenter will give what color of colonies?

a)

yellow

b)

blue

c)

pink

80.

E. coli strains differ based on ​ (a)   of the ​ (b)   endotoxin.

Choose from the below words
O antigen
LPS
81.

What are the E. coli strains?

a)

Uropathogenic (UPEC)

b)

Entero toxigenic (ETEC)

c)

Enterohemorrhagic (EHEC)

82.

E. coli strains:

Causes UTIs ​ (a)  

Causes watery diarrhea​ (b)  

Causes destruction of intestinal lining, kidney failure, hemolytic uremic syndrome ​ (c)  

Choose from the below words
UPEC
ETEC
EHEC
83.

Which E. coli strain produces a shiga toxin and causes bloody diarrhea?

a)

UPEC

b)

ETEC

c)

EHEC

84.

Which E. coli strain causes traveler's diarrhea?

a)

UPEC

b)

ETEC

c)

EHEC

85.

Klebsiella:

Gram​ (a)  

Oxygen: ​ (b)  

Oxidase:​ (c)  

Motility:​ (d)  

Ferments: ​ (e)  

Urease +

Choose from the below words
-
facultative anaerobe
non-motile
lactose
86.

Klebsiella is Urease ___

a)

+

b)

-

87.

Klebsiella is a component of the microbiota of the ____

a)

respiratory tract

b)

GU tract

c)

GI tract

d)

skin

88.

What are the virulence factors for Klebsiella?

a)

fimbriae

b)

siderophores

89.

What form of Klebsiella pneumoniae causes disease?

a)

encapsulated form

b)

nonencapsulated form

90.

Enterobacter:

Gram ​ (a)  

Oxygen: ​ (b)  

oxidase​ (c)  

ferments: ​ (d)  

Motility: ​ motile

Urease ​ (e)  

Choose from the below words
-
facultative anaerobe
lactose
+
91.

Enterobactor gram - bacilli

a)

component of the GI microbiota

b)

Nosocomial infections many types

92.

What type of transmission for enterobactore?

a)

horizontal transmission (patient to patient)

b)

vehicle transmission (catheters, tubing, wound dressings)

93.

Virulence factors of Enterobacteria.

a)

fimbriae

b)

adhesins

c)

LPS

d)

capsule and biofilms

e)

hemolysins, siderophores