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WorksheetsMed Micro Review
Total questions: 25
Worksheet time: 13mins
What makes up the barrier that separates the brain from potential pathogens in bodily fluids?
Cerebrospinal fluid
Blood
Endothelial cells
Bone
If a pathogen crosses directly through cells of the blood-brain barrier, this is called:
Paracellular entry
Transcellular entry
Trojan horse entry
Extracellular entry
Encephalitis is due to inflammation of the...
Meninges
Brain tissue
Spinal cord
Neisseria meningitidis uses ______ to adhere to brain endothelial cells.
Capsule
Type IV pili
Porin
Flagella
What is the primary reservoir of Neisseria meningitidis?
Human nasopharyngeal mucosa
Human brain tissue
Animal nasopharyngeal mucosa
Animal brain tissue
Which characteristic is common between Neisseria gonorrhoeae and Neisseria meningitidis?
Brain infections
Respiratory infections
Intracellular growth
Transmission mode
Which of the following is NOT associated with vaccine production?
mRNA
phagocytic cells
toxoids
recombinants
Treatment of the infectious agent with heat, detergents, or chemicals is used to create which type of vaccine?
Live attenuated
Inactivated
Toxoid
Subunit
The meningitis vaccine is what type of vaccine?
Live attenuated
Inactivated
Toxoid
Subunit
Which vaccine type is the least antigenic?
Live attenuated
Inactivated
Toxoid
Subunit
What is the Gram result for Borrelia burgdorferi?
Gram- rod
Gram+ cocci
Gram- diplococci
Gram- spirochaete
Borrelia burgdorferi is the causative agent of which disease?
Skin ulcers
Lyme disease
Pneumonia
Diarrhea
What is the primary reservoir for Borrelia burgdorferi?
Ticks
Deer
Humans
Mice
The Borrelia OspA protein is necessary for...
Attachment to tick salivary glands
Attachment to human brain epithelia
Blocking host complement protein
Inhibiting host blood coagulation
Droplets will settle in which part of the respiratory tract?
Nasal cavity
Bronchial tubes
Trachea
Alveoli
Which class of antibody is most abundant in bodily secretions (tears, saliva, etc.)?
IgM
IgG
IgA
IgE
What is the structure and nucleic acid of a coronavirus?
Enveloped nucleocapsid + RNA
Enveloped nucleocapsid + DNA
Enveloped + RNA
Enveloped + DNA
RNA virus replication requires which enzyme?
RNA-dependent DNA polymerase
RNA-dependent RNA polymerase
DNA-dependent DNA polymerase
DNA-dependent RNA polymerase
What is the primary mechanism by which antigenic drift occurs in influenza?
Recombination between different strains
Changes in host range
Incorporation of host DNA
Mutation in viral surface proteins
The influenza vaccine triggers production of antibodies to which antigen?
Capsule
Haemagglutinin
Neuraminidase
RNA genome
What is the host receptor of SARS-CoV-2?
ACE2
CD4
CCR5
What is a major virulence factor for Pseudomonas aeruginosa?
Coagulase
Capsule
Exotoxin A
Mucinase
Which is a common immune evasion strategy in Pseudomonas aeruginosa?
Spore production
Biofilm formation
Capsule variation
Inhibiting lysosome fusion
Which is a long-term effect of Mycobacterium tuberculosis infection?
Necrosis of lung tissue
Meningitis
Fever
Arthritis
Mycobacterium tuberculosis primarily infects which cell type?
Dendritic cells
Neuronal cells
Neutrophils
Alveolar macrophages
