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Antidepressant Medications Quiz

Total questions: 22

Worksheet time: 12mins

Name
Class
Date
1.

Which one of the following is not a class of antidepressant medications?

a)

SNRIs

b)

TCAs

c)

MAOIs

d)

ACEI

e)

SSRIs

2.

Which one of the following is not an antidepressant medication?

a)

Venlafaxine

b)

Amitriptyline

c)

Phenelzine

d)

Donepezil

e)

Sertraline

3.

A 36-year-old woman presents with symptoms of major depression that are unrelated to a general medical condition, bereavement, or substance abuse. She is not currently taking any prescription or over-the-counter medications. Drug treatment is to be initiated with paroxetine. In your information to the patient, you would tell her that

a)

It is preferable that she does not take the drug in the evening

b)

She should tell you if she anticipates using other prescription drugs

c)

The antidepressant effects of paroxetine may take 2 weeks or more to become effective

d)

All of the above

4.

A 34-year-old male patient who was prescribed citalopram for depression has decided he wants to stop taking the drug. When questioned, he said that it was affecting his sexual performance. You ascertain that he is also trying to overcome his dependency on tobacco products. If you decide to reinstitute drug therapy in this patient, the best choice would be

a)

Bupropion

b)

Fluoxetine

c)

Imipramine

d)

Venlafaxine

5.

A patient under treatment for a major depressive disorder is brought to the emergency department after ingesting 30 times the normal daily therapeutic dose of amitriptyline. In severe tricyclic antidepressant overdose, it would be of minimal value to

a)

Administer bicarbonate and potassium chloride (to correct acidosis and hypokalemia)

b)

Administer lidocaine (to control cardiac arrhythmias)

c)

Initiate hemodialysis (to hasten drug elimination)

d)

Maintain heart rhythm by electrical pacing

e)

Use intravenous diazepam to control seizures

6.

This drug, an antagonist at 5-HT2 receptors, is widely used for the management of insomnia.

a)

Citalopram

b)

Doxepin

c)

Trazodone

d)

Triazolam

e)

Zolpidem

7.

To be effective in breast cancer, tamoxifen must be converted to an active form by CYP2D6. Cases of inadequate treatment of breast cancer have occurred when tamoxifen was administered to patients who were being treated with

a)

Bupropion

b)

Fluoxetine

c)

Imipramine

d)

Phenelzine

8.

The above patient returns for follow-up 6 months later. He has joined a health club and has lost several pounds and notes "feeling better mentally." However, upon questioning he still has not returned to the activities he once enjoyed and is still not sleeping or eating well. The psychiatrist recommends increasing the dose of his selective serotonin reuptake inhibitor (SSRI). The patient reluctantly admits that he has not been taking his medication because of some of the side effects. Which one is likely to be the most bothersome?

a)

Weight gain

b)

Tachycardia

c)

Sexual dysfunction

d)

Tremor

9.

A 36-year-old man has been smoking two packs of cigarettes a day for the last 20 years. He is concerned that his health has deteriorated, and he has a persistent hacking cough. He also states that he doesn't want to "get lung cancer and die, like my father did." He has tried nicotine patches with no success and wants to know if there is any "pill" he could try. What medication could the physician recommend?

a)

Mirtazapine

b)

Citalopram

c)

Phenelzine

d)

Buspirone

e)

Bupropion

10.

Foods containing tyramine should be avoided when taken with which of the following medications?

a)

Amitriptyline

b)

Phenelzine

c)

Sertraline

d)

Bupropion

e)

Amlodipine

11.

Which of the following is a selective MAO-B inhibitor:

a)

Selegiline

b)

Clorgyline

c)

Moclobemide

d)

Tranylcypromine

12.

Which of the following MAO inhibitors is most likely to produce cheese reaction:

a)

Tranylcypromine

b)

Moclobemide

c)

Selegiline

d)

Clorgyline

13.

31.5 'Cheese reaction' in a MAO inhibited patient manifests as:

a)

Precipitous fall in blood pressure and shock

b)

Hypertensive crisis

c)

Acute manic episode

d)

Convulsions

14.

Of the following, choose the antidepressant having both high sedative and high anticholinergic activity:

a)

Imipramine

b)

Amitriptyline

c)

Fluoxetine

d)

Trazodone

15.

The antidepressant which selectively blocks 5-hydroxytryptamine uptake is:

a)

Fluoxetine

b)

Amoxapine

c)

Desipramine

d)

Dothiepin

16.

A 65-year-old man was brought to the hospital with complaints of pain in lower abdomen and not having passed urine for 16 hours. The bladder was found to be full. His son informed that he was depressed for the last 2 years and only the day before a doctor had given him some medicine. Which of the following drugs is he most likely to have received:

a)

Alprazolam

b)

Sertraline

c)

Amitryptyline

d)

Trazodone

17.

Tricyclic antidepressants abolish the antihypertensive action of the following drug:

a)

Enalapril

b)

Clonidine

c)

Atenolol

d)

Diltiazem

18.

Choose the selective serotonin reuptake inhibitor that is less likely to inhibit CYP2D6 and CYP3A4 resulting in fewer drug interactions:

a)

Sertraline

b)

Paroxetine

c)

Fluoxetine

d)

Fluvoxamine

19.

Which of the following is labelled as a 'serotonin and noradrenaline reuptake inhibitor or SNRI':

a)

Amineptine

b)

Venlafaxine

c)

Bupropion

d)

Citalopram

20.

A patient of endogenous depression was put on imipramine therapy. After what interval the therapeutic effect is likely to manifest:

a)

Three days

b)

One week

c)

Three weeks

d)

Three months

21.

Prolonged painful erection of penis has been noted particularly as a side effect of:

a)

Doxepin

b)

Citalopram

c)

Bupropion

d)

Trazodone

22.

Diabetic and other types of neuropathic pain often respond to:

a)

Chlorpromazine

b)

Diazepam

c)

Imipramine

d)

Lithium