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Worksheetsmiastenia gravis - biofisica AL
Total questions: 41
Worksheet time: 21mins
Sobre os sintomas oculares: O início dos problemas nos olhos foi:
De repente
Gradualmente
Sobre os sintomas oculares: O peso nos olhos piora ao longo do dia e melhora com o repouso?
Sim
Não
Sobre os sintomas oculares: Como você descreveria a dificuldade em fechar as pálpebras?
Constante
Intermitente
Não apresenta dificuldade
A exoftalmia surgiu de repente ou progressivamente?
De repente
Progressivamente
A visão turva ocorre:
Constantemente
Em momentos específicos
Em ambos os olhos
Apenas em um olho
O desconforto cervical anterior começou há quanto tempo?
Há poucos dias
Há semanas
Há meses
Não sei
Sobre o desconforto cervical anterior: Você apresenta dificuldade para engolir associada a esse desconforto?
Sim
Não
O desconforto na face e garganta é mais frequentemente descrito como:
Dor
Formigamento
Pressão
Outro
A voz nasalada que você percebeu é:
Constante
Intermitente
Não percebi voz nasalada
Não sei
Sobre a dificuldade em sorrir e parestesias faciais: Quando você notou a dificuldade em sorrir? Sente alguma fraqueza nos músculos da face?
Sim, sinto fraqueza nos músculos da face.
Não, não sinto fraqueza nos músculos da face.
Notei a dificuldade recentemente.
Não notei nenhuma dificuldade.
Sobre a dificuldade em sorrir e parestesias faciais: Em qual região do rosto você sente as parestesias ao sorrir?
Testa
Bochechas
Lábios
Queixo
A dificuldade em engolir começou há:
Menos de uma semana
1-4 semanas
Mais de um mês
Não sei
Você tem sentido fadiga ou fraqueza em outras partes do corpo?
Sim
Não
Você tem alguma história de doenças autoimunes na família ou pessoal?
Sim
Não
Você tem alguma outra condição médica conhecida?
Sim
Não
Selecione o tipo de medicamento que você está tomando atualmente:
Antibióticos
Analgésicos
Antidepressivos
Não estou tomando nenhum medicamento
Houve alguma mudança recente na sua saúde geral ou algum evento marcante antes do início desses sintomas?
Sim
Não
Which of the following is a classic symptom of Myasthenia Gravis (MG)?
Weight loss
Difficulty in completely closing the eyelids due to muscle weakness
High fever
Joint pain
What does 'ptose palpebral' (drooping of the eyelid) suggest in the context of Myasthenia Gravis?
It is highly suggestive of MG.
It rules out MG.
It is a sign of diabetes.
It is unrelated to neurological disorders.
Facial paresthesia and difficulty smiling are due to weakness of which muscles in Myasthenia Gravis?
Facial muscles
Extraocular muscles
Deltoid muscles
Gastrocnemius muscles
Which symptom is less common in Myasthenia Gravis and points to other conditions such as Graves' Disease?
Ptosis
Exophthalmos
Dysphagia
Nasal voice
Bulbar muscle involvement causing dysphagia is common in Myasthenia Gravis.
True
False
What is a possible visual symptom secondary to weakness of ocular muscles in Myasthenia Gravis?
Blurred vision or diplopia (double vision)
Sudden loss of consciousness
Hearing loss
Nasal congestion
The absence of significant changes in thyroid function tests would make which diagnosis less likely, despite the presence of exophthalmos?
Myasthenia Gravis
Graves' Disease
Multiple Sclerosis
Parkinson's Disease
What percentage of Myasthenia Gravis patients have anti-acetylcholine receptor antibodies?
86%
50%
30%
100%
In Myasthenia Gravis, what is the role of the thymus gland?
70% of patients have thymic enlargement (thymoma), and 10-15% have thymoma.
It produces antibodies against acetylcholine directly.
It is always atrophied in all patients.
It has no involvement in the disease process.
In normal neuromuscular junctions, acetylcholine is released from the presynaptic membrane and leads to muscle contraction.
True
False
Which of the following is NOT a typical finding in the neuromuscular junction of Myasthenia Gravis patients?
A) Reduction in the number of acetylcholine receptors
B) Increase in the size of the neuromuscular junction
C) Destruction of nerve terminals in the motor plate
D) Increase in acetylcholine production
What percentage of Myasthenia Gravis patients have anti-MuSK antibodies?
About 10%
About 1%
About 50%
About 30%
Fill in the blank: Grupo I (25%) – Miastenia ocular is characterized by fatigue and weakness in the external ocular muscles, affecting one or both eyes. The prognosis is ________, and muscle weakness does not spread to other muscle groups in the first two years.
excellent
poor
uncertain
fatal
Fill in the blank: Grupo IIA (35%) – Miastenia generalizada leve involves generalized, mild, and progressive MG, with involvement of cranial muscles, lower limbs, and trunk, sparing respiratory muscles. The prognosis is ________.
good
poor
uncertain
fatal
Fill in the blank: Grupo IIB (20%) – Miastenia generalizada moderada is characterized by generalized and moderately intense and progressive MG. The prognosis is relatively ________, with a less satisfactory therapeutic response than in Group IIA.
good
poor
uncertain
excellent
Fill in the blank: Grupo III (11%) – Miastenia aguda fulminante is characterized by rapid and progressive disease evolution, less than three months, leading to rapid and early atrophy of all ocular, skeletal, and bulbar muscles, including respiratory muscles. The prognosis is ________.
poor
excellent
uncertain
favorable
Fill in the blank: Grupo IV (9%) – Miastenia generalizada severa tardia is characterized by severe generalized MG that becomes generalized in the first or second year after onset. The prognosis is ________.
poor
excellent
uncertain
benign
According to the classification by Osserman and Genkins, which group of MG has the highest percentage of thymomas?
Grupo I
Grupo II
Grupo III
Grupo IV
Fill in the blank: Tipo I MG is characterized by the ________ of thymoma, with no relation to sex, and MG is usually intense.
presence
absence
recurrence
treatment
Fill in the blank: Tipo II MG is characterized by the ________ of thymoma and occurs predominantly in women before age 40.
absence
presence
enlargement
reduction
Fill in the blank: Tipo III MG is characterized by the absence of thymoma and occurs predominantly in ________ after age 40.
men
children
adolescents
women
Fill in the blank: Miastenia Gravis Juvenil is defined by the onset of signs and symptoms between the ________ and ________ year of age.
1st; 18th
2nd; 12th
5th; 21st
10th; 16th
Miastenia Gravis Autoimune Neonatal Transitória can occur in up to ________% of neonates born to mothers with MG.
10
1
25
50
Fill in the blank: Miastenia Familiar is associated with a genetic predisposition, and up to ________% of patients have a maternal relative with MG or other autoimmune diseases.
30
5
50
70
