WorksheetsRMO MS P31 8 Juni, RA Osteosarkoma Genu Varum
Total questions: 20
Worksheet time: 10mins
Which of the following statements is most accurate regarding the pathogenesis of Rheumatoid Arthritis?
Activation of B lymphocytes by viral infection causes joint damage
Immune complexes deposit in the kidneys and cause nephritis
Chronic inflammation of the synovium due to autoimmune activation
Bone damage is caused by the activation of mast cells
Autoimmunity directly attacks skeletal muscles
A characteristic radiologic finding in Rheumatoid Arthritis is:
Subchondral sclerosis
Symmetric joint space narrowing
Osteophyte formation
Widespread bone sclerosis
Multiple spontaneous fractures
Which of the following systemic features is commonly associated with RA?
Heart failure
Subcutaneous nodules
Jaundice
Pulmonary hypertension
Visual disturbances
Which joints are most commonly involved in early RA?
Knees and hips
Hips and elbows
MCP (metacarpophalangeal) and PIP (proximal interphalangeal) joints
Shoulders and ankles
Temporomandibular joints
The most specific laboratory test for diagnosing RA is…
ESR (erythrocyte sedimentation rate)
CRP (C-reactive protein)
Rheumatoid factor
Anti-CCP (anti-cyclic citrullinated peptide)
ANA (antinuclear antibody)
Which drug is considered the first-line treatment in RA?
Paracetamol
Methotrexate
Ibuprofen
Azathioprine
Colchicine
The following are classic hand deformities in RA, EXCEPT:
Ulnar deviation
Swan neck deformity
Boutonnière deformity
Heberden's nodes
Morning stiffness
Osteosarcoma most commonly affects:
Children under 5 years
Adolescents aged 10-20 years
Postmenopausal women
Elderly with osteoarthritis
Premature infants
The most common site of osteosarcoma is:
Thoracic vertebrae
Distal femur and proximal tibia (around the knee)
Metacarpals
Clavicle
Proximal humerus
A classic radiographic appearance of osteosarcoma is:
Ground-glass opacity
Onion skin appearance
Sunburst pattern
Soap bubble lesion
Crescent sign
The most common complication of osteosarcoma is:
Renal failure
Stress fractures
Pulmonary metastasis
Visual impairment
Severe hypertension
The definitive diagnosis of osteosarcoma is made by:
Blood tests
X-ray imaging
MRI
Bone biopsy
Abdominal CT scan
Primary treatment for localized osteosarcoma includes:
Radiotherapy alone
Chemotherapy plus surgical resection
Herbal therapy and rest
Physical therapy
Long-term antibiotics
Osteosarcoma is a malignant tumor originating from:
Squamous cells
Osteoblasts
Myeloid cells
Mast cells
Chondroblasts
Genu varum is characterized by:
Knees touching when standing
Ankles being very close together
Wide gap between knees when ankles are together
Excessive foot eversion during walking
Stiff knees at night
Physiological genu varum is commonly seen in:
Adolescent males
Premature babies
Children under 2 years old
Elderly individuals
Postmenopausal women
The most common pathological cause of genu varum is…
Vitamin D deficiency
Viral infection
Hip dislocation
Hyperinsulinism
Hemophilia
Severe genu varum may lead to the following complications, except…
Medial compartment osteoarthritis
Gait abnormalities
Knee pain
Myocardial infarction
Joint stress
The appropriate management of physiological genu varum is…
Immediate corrective surgery
Knee immobilization
Observation and parental reassurance
Long-term antibiotic therapy
Skeletal traction
The most useful imaging for severe genu varum is…
Liver function test
X-ray of the lower extremities
Chest CT scan
Brain MRI
Tuberculin skin test
