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Worksheets

Pharma Models Quiz

Total questions: 163

Worksheet time: 1hrs 24mins

Name
Class
Date
1.

Factors affecting simple diffusion include the following except :

a)

Gradient (Concentration of drugs & Electric of ions)

b)

Molecular weight & size.

c)

the presence of a protein carrier

2.

For weak base and acid drugs:

a)

The unionized (non-polar) form is lipid soluble and easily absorbed.

b)

The unionized (non-polar) form is water soluble and easily absorbed.

c)

Ionized (polar) form of drugs is lipid soluble and easily absorbed

3.

Filtration of drugs is characterized by the following except :

a)

Along hydrostatic and osmotic gradients

b)

No carrier or energy needed

c)

Molecular weight in more than 500

4.

Filtration of drugs is characterized by the following except :

a)

Along hydrostatic and osmotic gradients

b)

a protein carrier is needed

c)

Molecular weight in less than 500

5.

Facilitated Diffusion is characterized by the following except :

a)

Along concentration gradient

b)

Needs a protien carrier → Site for Saturation & Competition .

c)

Energy is needed.

6.

Active Transport is characterized by the following except :

a)

Against concentration gradient

b)

Needs a protien carrier

c)

No energy or enzymes are needed

7.

Absorption of Vit B12 + Intrinsic factor occurs by:

a)

Pinocytosis (Cell Drinking)

b)

Facilitated Diffusion

c)

Filtration

8.

Absorption of Glucose occurs by:

a)

Pinocytosis (Cell Drinking)

b)

Facilitated Diffusion

c)

Active Transport

9.

Factors affecting absorption include the following except :

a)

solubility, ionization , and valency of Drugs.

b)

route of administration, surface area and vascularity.

c)

number of plasma proteins

10.

Disadvantages of Oral route include the following except :.

a)

rapid onset.

b)

produce G.I.T. upsets.

c)

first pass effect.

11.

Sublingual route is characterized by the following except :.

a)

Rapid onset .

b)

Bypass first pass effect

c)

The drug could be irritant or acidic.

12.

First pass effect to the drugs:

a)

It can occur in the GIT or liver

b)

It can occur in the kidney

c)

It can occur in the lung.

13.

Rectal route is characterized by the following except :

a)

Slow onset

b)

Bypass first pass effect,

c)

Useful in vomiting and uncooperative patients,

14.

Increase absorption of Sub cutaneous injection by except :

a)

massage and heat

b)

combine drug with hyaluronidase enzyme

c)

combine drug with adrenaline

15.

Intramuscular injection is characterized by the following except:

a)

slow absorption

b)

drugs may be irritant.

c)

drugs may be water soluble, suspension, or oil

16.

Parenteral routes include the following except:

a)

Subcutaneous pellet implantation

b)

intra bone marrow route

c)

sublingual route

17.

Intra venous route has the following advantages except:

a)

100 % bioavailability ,

b)

suitable in irritant and large volumes drugs.

c)

lipid soluble drugs could be given.

18.

Skin rout of absorption can be enhanced by except:

a)

Ionophoresis.

b)

Inunction.

c)

Cooling the skin

19.

skin and transdermal delivery system has the following advantages except:

a)

prolonged blood level with minimal fluctuations,

b)

Better patient compliance.

c)

it needs low lipid solubility of drugs

20.

Drugs bound to plasma protein are characterized by the following except:

a)

depot form of drugs.

b)

site for drug interactions.

c)

Easily excreted.

21.

Two compartments distribution of drugs include the following except:

a)

Ionized form of drugs

b)

High molecular weight drugs.

c)

Non bound form of drugs

22.

Distribution of drugs All over the body include the following except:

a)

Non-ionized form of drugs.

b)

low molecular weight drugs.

c)

bound form of drugs.

23.

Placental Barrier is characterized by the following except:

a)

composed of Epithelium of Fetal Villi & Capillary endothelium.

b)

poor in enzymatic activity.

c)

Drugs that pass placental barrier may cause Neonatal malformations .

24.

The following are examples of phase I metabolism except:

a)

Hydrolysis of Di-acetyl-morphine → Acetic acid + Morphine .

b)

Toxification of Methyl alcohol → Formaldehyde

c)

Conjugation of Glucuronic acid with Aspirin.

25.

The following are examples of phase II metabolism except:

a)

Conjugation of Glucuronic acid with Aspirin.

b)

acetylation of sulphonamide

c)

Toxification of Methyl alcohol → Formaldehyde

26.

Nicotine Site Of Biotransformation:

a)

liver,

b)

kidney,

c)

lung

27.

Succinylcholine is metabolized by Cholinesterase enzyme in:

a)

Liver ,

b)

Lung,

c)

plasma

28.

Hepatic Microsomal Enzyme Inducers include the following except:

a)

Cortisol

b)

Tobacco smoking

c)

Estrogen

29.

Hepatic Microsomal Enzyme Inhibitors cause the following except:

a)

decrease the duration of action of drugs.

b)

increase the duration of action of drugs

c)

They do not cause Tolerance.

30.

Hepatic Microsomal Enzyme Inhibitors include the following except:

a)

Grapefruit,

b)

Ozone

c)

Tobacco smoking

31.

Drugs bound to plasma protein are characterized by the following except:

a)

not Active

b)

not Metabolized

c)

easily Excreted

32.

Drugs bound to plasma protein are characterized by the following except:

a)

not Filte

b)

Longer duration

c)

Easily Metabolized

33.

calcium is stored in:

a)

Bone.

b)

hair.

c)

thyroid gland.

34.

vitamine B12 is stored in:

a)

Liver.

b)

heart.

c)

bone

35.

Iodine is stored in: -

a)

Bone.

b)

hair.

c)

thyroid gland.

36.

Oxidation is

a)

Phase-I biotransformation

b)

Phase-II biotransformation

c)

non of the above

37.

Reductionis :

a)

Phase-I biotransformation

b)

Phase-II biotransformation

c)

non of the above

38.

Hydrolysis is:

a)

Phase-I biotransformation

b)

Phase-II biotransformation

c)

non of the above

39.

Vitamin D Site Of Biotransformation:

a)

Plasma

b)

Lung

c)

Skin

40.

Age affects hepatic microsomal enzymes (H.M.E) in the following way:

a)

H.M.E. Activity is inhibited in extremities of age.

b)

H.M.E. Activity is stimulated in extremities of age.

c)

age has no effect

41.

Renal Excretion mainly affects:

a)

Non-volatile drugs and metabolites

b)

volatile drugs and metabolites

c)

non of the above

42.

Renal Excretion include the following except:

a)

Passive Glomerular filtration

b)

Active Tubular Excretion.

c)

Active Glomerular filtration

43.

Active Tubular Excretion is characterized by the following except:

a)

Saturable and Site for competition & Drug Interaction

b)

Affects both Weak acid and Weak base drugs

c)

Changes in urinary pH does not Affect excretion

44.

Alkalinization of urine (Na or K Acetate, Bicarbonate):

4 lines
45.

Alkalinization of urine (Na or K Acetate, Bicarbonate):

a)

Renal excretion of weak Acid drugs e.g. Aspirin

b)

Renal excretion of weak Base drugs e.g. Ephedrine & Amphetamine.

c)

has no effect

46.

Acidification of Urine (NH4Cl or “Vit C”):

a)

Renal excretion of weak Acid drugs e.g. Aspirin

b)

Renal excretion of weak Base drugs e.g. Ephedrine & Amphetamine.

c)

has no effect

47.

Lung excretion is applied to:

a)

Gases & Volatile Liquids

b)

Non-volatile drugs and metabolites

c)

no drugs are excreted

48.

eye& ear drops act by:

a)

Local or Topical Action

b)

Systemic or General Action

c)

Reflex or Remote Action

49.

Intra-articular injections act by:

a)

Local or Topical Action

b)

Systemic or General Action

c)

Reflex or Remote Action

50.

Subcutaneous (SC) adrenaline act by:

a)

Local or Topical Action

b)

Systemic or General Action

c)

Reflex or Remote Action

51.

Subcutaneous SC Camphor act by:

a)

Local or Topical Action

b)

Systemic or General Action

c)

Reflex or Remote Action

52.

Oral aspirin act by:

a)

Local or Topical Action

b)

Systemic or General Action

c)

Reflex or Remote Action

53.

Kaolin & Activated charcoal in diarrhea act by:

a)

Adsorption

b)

Osmotic effect.

c)

Demulcent effect

54.

Mechanism of action of Mannitol as a diuretic:

a)

Adsorption

b)

Osmotic effect.

c)

Demulcent effect

55.

Mechanism of action of Liquorice as an anti-tussive:

a)

Adsorption

b)

Osmotic effect.

c)

Demulcent effect

56.

Mechanism of action of NaHCO3 (Antacid):

a)

Neutralization:

b)

Chelation

c)

Demulcent effect

57.

Heavy metal toxicity is treated by:

a)

Neutralization.

b)

Chelation

c)

Demulcent effect

58.

Calcium (Ca+2) toxicity is treated by:

a)

Sodium Edetate

b)

Dimercaprol

c)

NaHCO3

59.

Anti-cancer drugs act by:

a)

Interference with Cell Division

b)

Interference with Metabolic Pathway or Enzymes

c)

Chemical Chelation

60.

NaHCO3 (Antacid) in treatment of hyperacidity act by:

a)

Neutralization.

b)

Chelation

c)

Demulcent effect

61.

Sulfonamides compete with PABA in bacteria and leads to:

a)

Inhibit synthesis of folic acid.

b)

Interfere with Metabolic Pathway.

c)

All the above

62.

Local anesthetics block:

a)

Sodium (Na+) channels

b)

Calcium channels

c)

Potassium channels

63.

Adrenaline + β-receptors is:

a)

Ligand-gated Ion Channels(Type I receptor)

b)

Coupled to G-protein(Type II receptor)

c)

Coupled to Kinase Activity (Type III receptor)

64.

Acetyl. Choline. + Nicotinic receptors is:

a)

Ligand-gated Ion Channels(Type I receptor)

b)

Coupled to G-protein(Type II receptor)

c)

Coupled to Kinase Activity (Type III receptor)

65.

Insulin receptors are:

a)

Ligand-gated Ion Channels(Type I receptor)

b)

Coupled to G-protein(Type II receptor)

c)

Coupled to Kinase Activity (Type III receptor)

66.

Thyroid & Steroid hormones act by:

a)

Intracellular receptors and Modulation of DNA Transcription

b)

Ligand-gated Ion Channels

c)

Kinase Activity

67.

The amount of response to Drug/Receptor Complex depends on:

a)

number of receptors occupied by the drug.

b)

Rates of association (Ka) & dissociation (Kd) of D/R complex.

c)

All of the above

68.

Occupation Theory means:

a)

The amount of action is directly proportional with the number of receptors occupied by the drug

b)

The amount of action is directly proportional with Rates of association (Ka) & dissociation (Kd) of D/R complex.

c)

The amount of action is directly proportional with the number of Spare receptors.

69.

Rate Theory of Paton means:

a)

The amount of action is directly proportional with the number of receptors occupied by the drug

b)

The amount of action is directly proportional with Rates of association (Ka) & dissociation (Kd) of D/R complex.

c)

The amount of action is directly proportional with the number of Spare receptors.

70.

An agonist ligand has all the following except:

a)

Affinity.

b)

High intrinsic activity(efficacy)

c)

blocking of the receptor.

71.

An antagonist ligand has all the following except:

a)

Affinity.

b)

No efficacy

c)

Rapid rates of association (Ka) & dissociation (Kd).

72.

Partial Agonists has all the following except:

a)

Affinity.

b)

high intrinsic activity

c)

Moderate rates of association & dissociation.

73.

Partial Agonists has all the following except:

a)

Produces initial stimulation then block of the receptor

b)

If used in presence of an agonist → Block the action of the agonist.

c)

Rapid rates of association (Ka) & dissociation (Kd).

74.

Competitive block means:

a)

Blocker is displaced by excess agonist

b)

Blocker is not displaced by excess agonist

75.

Non-competitive block means:

a)

Blocker is displaced by excess agonist

b)

Blocker is not displaced by excess agonist

76.

Secondary Effects means:

a)

Unavoidable undesirable normal action produced by therapeutic dose of the drug.

b)

Exaggerated normal action due to high blood level of the drug

c)

Exaggerated normal action in response to small therapeutic dose of the drug.

77.

Over-dose means:

a)

Unavoidable undesirable normal action produced by therapeutic dose of the drug.

b)

Exaggerated normal action due to high blood level of the drug

c)

Exaggerated normal action in response to small therapeutic dose of the drug

78.

Supersensitivity (Intolerance) means:

a)

Unavoidable undesirable normal action produced by therapeutic dose of the drug.

b)

Exaggerated normal action due to high blood level of the drug

c)

Exaggerated normal action in response to small therapeutic dose of the drug

79.

Hyperthyroidism → Super sensitivity to sympathomimetics is an example of:

a)

Secondary Effects

b)

Over-dose

c)

Supersensitivity (Intolerance)

80.

Insulin large dose leading to hypoglycemia is an example of:

a)

Secondary Effects

b)

Over-dose

c)

Supersensitivity (Intolerance)

81.

Oral broad spectrum antibiotics leading to inhibition of Intestinal bacterial flora is an example of:

a)

Secondary Effects

b)

Over-dose

c)

Supersensitivity (Intolerance)

82.

Tolerance means:

a)

decreased or failed response to drugs.

b)

Exaggerated normal action in response to small therapeutic dose of the drug

c)

Exaggerated normal action due to high blood level of the drug

83.

Types of Congenital (Inborn) Tolerance include the following Except:

a)

Racial.

b)

Species.

84.

Types of Congenital (Inborn) Tolerance include the following Except:

a)

Racial.

b)

Species.

c)

Tachyphylaxis.

85.

Types of Acquired Tolerance include the following Except:

a)

Cross Tolerance between similar drugs

b)

Tachyphylaxis (Acute acquired tolerance)

c)

Species difference.

86.

Bacterial resistance to antimicrobials is considered a type of :

a)

Congenital (Inborn) Tolerance

b)

Acquired Tolerance.

c)

Intolerance

87.

Tachyphylaxis is considered a type of :

a)

Congenital (Inborn) Tolerance

b)

Acquired Tolerance

c)

Intolerance

88.

Individual (Biological) variations within any population is considered a type of :

a)

Congenital (Inborn) Tolerance

b)

Acquired Tolerance

c)

Intolerance

89.

Cross Tolerance between similar drugs is considered a type of :

a)

Congenital (Inborn) Tolerance

b)

Acquired Tolerance

c)

Intolerance

90.

Mechanism of Acquired Tolerance include the following except:

a)

A decrease in Absorption.

b)

An increase in Metabolism.

c)

A decrease in Excretion

91.

Characteristics of Acquired Tolerance include the following except:

a)

It is a temporary process

b)

Varies from one drug to another

c)

Affect all actions to the same extent

92.

Characteristics of Acquired Tolerance include the following except:

a)

It is a permanent process

b)

Varies from one drug to another

c)

Does not affect all actions to the same extent

93.

Sudden stop of Xanthine beverages leads to :

a)

Psychic dependence

b)

Psychic and Physical dependence

c)

Non of the above

94.

Sudden stop of the ethanol leads to :

a)

Psychic dependence

b)

Psychic and Physical dependence

c)

Non of the above

95.

Xanthine beverages Dependence is an example to :

a)

Habituation

b)

Addiction

c)

Non of the above

96.

amphetamine, morphine, Dependence are examples to :

a)

Habituation

b)

Addiction

c)

Non of the above

97.

Metoclopramide increase gastric Motility and leads to:

a)

increase Absorption of Paracetamol

b)

decrease Absorption of Paracetamol

c)

Non of the above

98.

Acid stomach:

a)

increase Absorption of weak acid drugs

b)

increase Absorption of weak alkaline drugs

c)

Non of the above

99.

Alkaline intestine:

a)

increase Absorption of weak acid drugs

b)

increase Absorption of weak alkaline drugs

c)

Non of the above

100.

Aspirin is better absorbed by:

a)

acid stomach

b)

alkaline intestine

c)

Non of the above

101.

decreased absorption of Ca , Mg, Al, & ferrous iron by :

a)

Tetracyclines

b)

Sulphonamides

c)

Ampicillin

102.

Oral anticoagulants are displaced from their plasma binding sites by:

a)

Aspirin

b)

Sulphonamides

c)

Ampicillin

103.

Oral hypoglycemic are displaced from their plasma binding sites by:

a)

Aspirin

b)

Sulphonamides

c)

Ampicilli

104.

When Oral hypoglycemic are displaced from their plasma binding sites:

a)

increase Their activity.

b)

decrease Their metabolism

c)

decrease Their excretion

105.

Hepatic Microsomal Enzymes inducers cause:

a)

Metabolism of other drugs

b)

Metabolism of other drugs

c)

decrease Their excretion

106.

nicotine causes:

a)

Metabolism of other drugs

b)

Metabolism of other drugs

c)

decrease Their excretion

107.

Estrogen causes:

a)

Metabolism of other drugs

b)

Metabolism of other drugs

c)

decrease Their excretion

108.

Alkalinization of urine by NaHCO3 causes:

a)

increase Excretion of weak acid drugs.

b)

decrease Excretion of weak acid drugs

c)

no effect

109.

Addition (Summation) means:

a)

Active drug + Active drug = Algebraic sum of activity

b)

Active drug + Active drug = More than algebraic sum of activity

c)

Inactive drug (inert) increases the activity of Active Drug

110.

Synergism means:

a)

Active drug + Active drug = Algebraic sum of activity

b)

Active drug + Active drug = More than algebraic sum of activity

c)

Inactive drug (inert) increases the activity of Active Drug

111.

Potentiation means:

a)

Active drug + Active drug = Algebraic sum of activity

b)

Active drug + Active drug = More than algebraic sum of activity

c)

Inactive drug (inert) increases the activity of Active Drug

112.

the effects of AcetylCholine + Histamine on intestinal contractility are example of:

a)

Summation

b)

Synergism

c)

Potentiation

113.

the effects of Ethanol + Morphine on depression of CNS are example of:

a)

Summation

b)

Synergism

c)

Potentiation

114.

the analgesic effects of caffeine with aspirin are example of:

a)

Summation

b)

Synergism

c)

Potentiation

115.

2Agonists + 2 Receptors +2 Opposing actions are example of:

a)

Chemical Antagonism

b)

Physiological. Antagonism

c)

Pharmacological Antagonism

116.

One Agonist + One Blocker + One Receptor are example of:

a)

Chemical Antagonism

b)

Physiological. Antagonism

c)

Pharmacological Antagonism

117.

Iatrogenic Disease means:

a)

Drug-induced disease.

b)

Drug-induced fetal malformations

c)

supersenstivity to drugs

118.

Large dose of Cortisol causes:

a)

Cushing’s disease

b)

Parkinsonism

c)

Non of the above

119.

Teratogenicity means:

a)

Drug-induced disease.

b)

Drug-induced fetal malformations

c)

supersenstivity to drugs

120.

When Phenytoin is taken during the first trimester it may cause:

a)

Hare lip and cleft palate

b)

Cardiac septal defects

c)

Teeth & Bone abnormalities

121.

When Aspirin is taken during the first trimester it may cause:

a)

Hare lip and cleft palate

b)

Cardiac septal defects

c)

Teeth & Bone abnormalities

122.

When Tetracycline is taken during the first trimester it may cause:

a)

Hare lip and cleft palate

b)

Cardiac septal defects

c)

Teeth & Bone abnormalities

123.

Halothane in general anaesthesia may cause:

a)

Cardio(heart)-toxicity

b)

Nephro(kidney)-toxicity

c)

Neuro-toxicity

124.

Paracetamol(panadol) may cause :

a)

Cardio-toxicity

b)

hepato(liver)-toxicity

c)

Neuro-toxicity

125.

Anti-thyroid drugs may cause:

a)

Cardio-toxicity

b)

Nephro-toxicity

c)

Bone marrow inhibition

126.

Idiosyncrasy:

a)

Unpredictable abnormal response to drugs due to antigen/antibody reaction.

b)

Unpredictable abnormal response due to genetic abnormality.

c)

Unpredictable abnormal response due to supersenstivity

127.

Idiosyncrasy:

a)

Occurs on first exposure

b)

Occurs on repeated exposure

c)

Occurs on second exposure

128.

Hemolytic anemia in patients with Favism is a type of

a)

Idiosyncrasy

b)

Hypersensitivity

c)

supersenstivity

129.

Succinylcholine apnea is caused by:

a)

abnormal Pseudo-cholinesterase activity.

b)

Glucose-6-Phosphate-Dehydrogenase enzyme deficiency.

c)

Hypersensitivity reaction

130.

Bioavailability after intravenous injection is :

a)

100%

b)

70%

c)

50%

131.

Simple Diffusion characteristics include the following except :

a)

Along concentration gradient

b)

Needs NO carrier

c)

Needs energy

132.

factors affecting simple diffusion include the following except :

a)

Gradient(Concentration of drugs & Electric of ions)

b)

Molecular weight & size.

c)

the presence of a protein carrier

133.

For weak base and acid drugs:

a)

The unionized (non-polar) form is lipid soluble and easily absorbed.

b)

The unionized (non-polar) form is water soluble and easily absorbed.

c)

Ionized (polar) form of drugs is lipid soluble and easily absorbed

134.

Filtration of drugs is characterized by the following except :

a)

Along hydrostatic and osmotic gradients

b)

No carrier or energy needed

c)

Molecular weight in more than 500

135.

Filtration of drugs is characterized by the following except :

a)

Along hydrostatic and osmotic gradients

b)

a protein carrier is needed

c)

Molecular weight in less than 500

136.

Filtration of drugs is characterized by the following except :

a)

againest hydrostatic and osmotic gradients

b)

No carrier or energy needed

c)

Molecular weight in less than 500

137.

Filtration of drugs is defined as:

a)

Passage of drugs through capillary endothelium & Glomeruli of the kidney along hydrostatic and osmotic gradients

b)

Passage of drugs through respiratory tract endothelium along hydrostatic and osmotic gradients

c)

Passage of drugs through blood brain barrier endothelium along hydrostatic and osmotic gradients

138.

Facilitated Diffusion is characterized by the following except :

a)

Along concentration gradient

b)

Needs a protien carrier → Site for Saturation & Competition (Interaction)

c)

Energy is needed.

139.

Active Transport is characterized by the following except :

a)

Against concentration gradient

b)

Needs a protien carrier

c)

No energy or enzymes are needed

140.

Absorption of Vit B12 + Intrinsic factor occurs by:

a)

Pinocytosis (Cell Drinking)

b)

Facilitated Diffusion

c)

Filtration

141.

Absorption of most of small Lipid soluble drugs Along concentration gradient occurs by:

a)

Pinocytosis (Cell Drinking)

b)

simple Diffusion

c)

Active Transport

142.

Absorption of Glucose occurs by:

a)

Pinocytosis (Cell Drinking)

b)

Facilitated Diffusion

c)

Active Transport

143.

Na+/K+ pump is taken place by:

a)

Pinocytosis (Cell Drinking)

b)

simple Diffusion

c)

Active Transport

144.

Factors affecting absorption include the following except :

a)

solubility, ionization , and valency of Drugs.

b)

route of administration, surface area and vascularity.

c)

number of plasma protiens

145.

Enteral routes of administration include the following except :

a)

sublingual

b)

oral.

c)

subcutaneous

146.

Advantages of Oral route include the following except :

a)

safety .

b)

economics

c)

needs sterilization

147.

Disdvantages of Oral route include the following except :.

a)

economic

b)

produce G.I.T. upsets.

c)

first pass effect.

148.

sublingual route is characterized by the following except :.

a)

Rapid onset

b)

bypass first pass effect

c)

the drug could be irritant or acidic.

149.

first pass effect to the drugs:

a)

It can occur in the GIT or liver

b)

It can occur in the kidney

c)

It can occur in the lung.

150.

Rectal route is characterized by the following except :

a)

slow onset,

b)

bypass first pass effect,

c)

useful in vomiting and uncooperative patients,

151.

Rectal route is characterized by the following except :

a)

rapid onset,

b)

affected by first pass effect,

c)

useful in irritant drugs and large volume drugs.

152.

Increase absorption of Sub cutaneous injection by except :

a)

massage and heat

b)

combine drug with hyaluronidase enzyme

c)

combine drug with adrenaline

153.

Intramuscular injection is characterized by the following except:

a)

slow absorption

b)

drugs may be irritant.

c)

drugs may be water soluble, suspension, or oil

154.

Parenteral routes include the following except:

a)

Subcutaneous pellet implantation

b)

intra bone marrow route

c)

sublingual route

155.

Parenteral routes include the following except:

a)

intraperitoneal route.

b)

intrathecal route.

c)

rectal route

156.

intra venous route has the following advantages except:

a)

100 % bioavailability ,

b)

suitable in large volumes drugs.

c)

lipid soluble drugs could be given.

157.

Inhalation has the following advantages except:

a)

Excellent absorption ( wide surface area , rich blood vessels) .

b)

The drug may be gas, vapour, solution, powder.

c)

suitable in irritant drug

158.

Skin rout of absorption can be enhanced by except :

a)

Ionophoresis.

b)

Inunction.

c)

Cooling the skin

159.

skin and transdermal delivery system has the following advantages except:

a)

prolonged blood level with minimal fluctuations,

b)

Better patient compliance.

c)

it needs low lipid solubility of drugs

160.

Drugs bound to plasma proteins are characterized by the following except:

a)

not Active

b)

not Metabolized

c)

easily Excreted

161.

Drugs bound to plasma proteins are characterized by the following except:

a)

not Filtered

b)

Longer duration

c)

Easily Metabolized

162.

The Free fraction of the drug is characterized by the following except:

a)

active.

b)

Easily metabolized.

c)

Considered a depot (reservoir)form

163.

Drugs bound to plasma proteins are characterized by the following except:

a)

depot (reservoir)form of drugs.

b)

site for drug interactions.