Which isotype of immunoglobulin is involved in type I hypersensitivity?

Which of the following diseases is an example of type II hypersensitivity?

Hypersensitivities to poison ivy and nickel are:

Type I hypersensitivity involves:

An example of a condition that involves type III hypersensitivity is:

A hypersensitivity reaction characterized by the presence of IgG that reacts with soluble antigen best describes:

Which of the following occurs in hemolytic disease of the newborn?

A direct antiglobulin test is ordered on a patient sample. This test detects:

What is meant by “gating” in flow cytometry?

As measured in flow cytometry, cells that are the smallest and have the least granules would be identified as:

In flow cytometry, if there are two light detectors, what does the amount of side scatter indicate?

Identify the difference between batch and random-access analyzers.

The lowest measurable amount of an analyte is called:

Which description best describes the reportable range?

In flow cytometry, forward scatter provides a measure of:

Flow cytometry is commonly used to:

The ability to consistently reproduce the same result on repeated testing of the same sample is called:

Random access analyzers were designed to do which of the following?

A 10-year-old girl visits her physician's office because she has been complaining about being thirsty and having to go to the bathroom all the time. She has lost 15 pounds over the past 6 months and has been more irritable than usual, especially after meals. The girl's fasting blood glucose is 575 mg/dL (reference range, < 100 mg/dL), her HbA1c is 9.0% (reference range, less 6.5%), and she has autoantibodies against glutamic acid decarboxylase and insulin. On the basis of these findings, a likely diagnosis for this girl is:

A 56-year-old woman presents to her physician complaining of weight gain and joint problems. She is having increasing difficulty walking up stairs and manipulating her fingers. Her fingers in both hands as well as her knees on both legs are equally painful and stiff. The symptoms have been getting progressively worse over the past 6 months. Rheumatoid factor is elevated, and antinuclear antibodies are not detected. Complement levels in her joints are decreased.

A 30-year-old clinical laboratory science student complains of being tired but is not able to sleep. The woman also states that her hair has been breaking off, and she has lost 20 pounds over the past 2 months without trying. The woman's pulse and blood pressure are elevated, and her eyes seem to be bulging. Her complete blood count (CBC) is normal, thyroid-stimulating hormone is decreased, and FT4 is increased. Antimicrosomal and antithyroglobulin antibodies are each 1:400. This woman most likely has:

Which laboratory finding is associated with multiple sclerosis?

Systemic lupus erythematosus is characterized by:

A disease characterized by hypoactivity of the thyroid with weight gain and a sluggish metabolism as a result of destruction of thyroglobulin best describes:

Autoimmune hemolytic anemia targets which cells or tissues?

In which of the following autoimmune diseases are antibodies to acetylcholine receptors produced, thereby blocking the signal to activate muscles?

Antibodies to cyclic citrullinated proteins (anti-CCP) are specific diagnostic indicators for:

Central tolerance, in which lymphocytes learn to distinguish between self-antigens and foreign antigens, takes place in the thymus and:

A patient undergoes a skin graft from the back to cover a damaged area on the neck. This is an example of what type of transplant?

In a patient who is exhibiting signs of graft-versus-host disease, which cell type is most likely responsible for the reaction?

To determine a patient’s HLA type using the complement-dependent cytotoxicity test, which of the following must be used?

Which of the following is a class II MHC protein involved in transplant immunology?

An experimental procedure applying porcine skin to burn victims is an example of a(n):

To detect HLA antibodies in a patient:

A tumor that is classified as malignant is described as:

A tumor-specific antigen is:

Which of the following is a general marker for all known human tumors?

Which of the following is a clinical application for tumor markers?

A woman who has a history of ovarian cancer in her family goes to her physician for a "cancer test." What is the test that is most likely to be positive if the woman has ovarian cancer?

Which of the following tumor markers is used to test for hepatocellular carcinoma?

Which is not a phase of immunoediting?

The administration of cytokines is a form of _______ immunotherapy.

If a tumor marker is sensitive it means:

If a tumor marker demonstrates that patients with higher levels tend to have worse outcomes, it can be used as a marker for:

Which of the following is an adaptive immune defense against tumor cells?

RPR stands for:

Which of the following is a cause of a biological false positive in the nontreponemal assays for syphilis?

A laboratory test that is used to confirm syphilis and detects specific treponemal antibodies is:

A patient presents with a painless genital ulcer. The patient is then diagnosed as having syphilis. In what stage of syphilis is the patient?

A patient presents with personality changes, altered mental state, and delusions of grandeur. The patient is then diagnosed as having syphilis. The patient is most likely in which stage of syphilis?

Lyme disease is caused by:

Tests for specific treponemal antibody include which of the following?

The vectors that transmit B. burgdorferi from natural reservoirs to humans are:

The clinical hallmark of early Lyme disease infection is:

Which antigen can be routinely detected in the blood of a person who has recently been infected with HIV?

Which of the following is considered the best indicator of immune function in HIV-infected individuals?

Which of the following is not a major route of HIV transmission?

What host antigen serves as the receptor for HIV?

Based on current CDC recommendations, initial screening for HIV should be performed by:

Which marker is elevated in the initial weeks after HIV infection?

When assessing HIV-infected patients for drug resistance, the testing methodology is: