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midterm and pre finals

Total questions: 84

Worksheet time: 42mins

Name
Class
Date
1.

what is the phenol-containing compound isolated from clove oil?

a)

A. Euganol

b)

B. Resorcinol

c)

C. Cresol

d)

D. Hexylresorcinol

e)

E. Menthol

2.

Green Vitriol is chemically known as

a)

A. Copper Sulfate

b)

B. Magnesium Sulfate

c)

C. Sodium sulfate

d)

D. Ferrous Sulfate

e)

E. Cuprous oxide

3.

What is the compound present in chalybeate pills?

a)

A. Ferrous Sulfate

b)

B. Ferrous carbonate

c)

C. Aluminum Carbonate

d)

D. Lead carbonate

e)

E. Ferrous gluconate

4.

what is the best antidote for phosphorus poising?

a)

A. NaCl

b)

B. EDTA

c)

C. NaHCO3

d)

D. MgSO4

e)

E. CuSO4

5.

in REDOX reaction, the reducing agent

a)

A. Is Oxidized

b)

B. Is reduced

c)

C. Gains electrons

d)

D. Decreased in oxidation state

e)

E. None of the above

6.

which of the following glass type make use of water attack test type?

a)

A. Type l

b)

B. Type ll

c)

C. Type lll

d)

D. Type lV

e)

E. Type NP

7.

This is an effective antidote for the treatment of poisoning by copper

a)

A. Penicillamine

b)

B. Dimercaprol

c)

C. Lugol's solution

d)

D. EDTA

e)

E. NaCl

8.

what is the chemical composition of red precipitate?

a)

A. Cuprous oxide

b)

B. Lead sulfide

c)

C. Mercuric oxide

d)

D. Beryllium oxide

e)

E. Ferrous sulfate

9.

Flourine inhibits caries formation via

a)

A. Decrease acid solubility of enamel

b)

B. Bacteria inhibition

c)

C. increase solubility of enamel

d)

D. A and B

e)

E. B and C

10.

which among the following statement about lead is NOT true?

a)

A. it precipitates proteins

b)

B. its actions is cumulative

c)

C. insoluble lead salt are converted to lead chloride in the stomach

d)

D. it burns with bluish flame

e)

E. None of the above

11.

Burnett syndrome is associated with the prolonged used of calcium containing antacid

a)

A. Magnesium Containing antacid

b)

B. Aluminum containing antacid

c)

C. Magnesium containing

d)

D. Simethicone containing antacid

e)

E. Sodium bicarbonate antacid

12.

Which iron compound has a superior resistance to oxidation upon exposure to air?

a)

A. Ferrous oxide

b)

B. Ferrous fumarate

c)

C. Ferrous gluconate

d)

D. Ferrous sulfate

13.

what mineral is deficient in parakeratosis

a)

A. Zinc

b)

B. Copper

c)

C. Magnesium

d)

D. Iodine

e)

E. Chromium

14.

what material is produced upon the fusion of pure with base such as sodium carbonate

a)

A. Pumice

b)

B. Quartz

c)

C. Glass

d)

D. Talc

e)

E. Kaolin

15.

one hundred volumes of hydrogen peroxide is equal to

a)

A. 3%

b)

B. 6%

c)

C. 10%

d)

D. 30%

e)

E. 100%

16.

Iron oxides are usually employed as

a)

A. Topical Protective

b)

B. Astringent

c)

C. Hematinic

d)

D. Laxative

e)

E. Pigment

17.

Aromatic ammonia spirit, USP must be stored in

a)

A. Amber bottles

b)

B. Clear glass container

c)

C. Green bottles

d)

D. Rubber containers

18.

what is the only route approved for the administration of dexran injection?

a)

A. Intraperitonial

b)

B. Intradermal

c)

C. Instramuscular

d)

D. Subcutaneous

e)

E. None of the above

19.

which of the following compounds are efflorescent substances?

l. Glauber's salt

ll. Blue vitrol

lll. Epsom salt

a)

A. l and ll

b)

B. l and lll

c)

C. ll and lll

d)

D. l,ll,lll

20.

Compounds capable of interfering with the passage of x-rays are employed as

a)

A. Lavage

b)

B. Chemotherapeutic agent

c)

C. Radiopaque

d)

D. Radioisotope

e)

E. Enema

21.

used as bone replacement for temporary braces of long bones and to close openings in the skull

a)

A. Silver

b)

B. Tantalum

c)

C. Platinum

d)

D. Zinc-euganol cement

e)

E. Calcium sulfate

22.

This drug is an example of

a)

A. Cell wall synthesis inhibitor

b)

B. Cell membrane disruptor

c)

C. Protein synthesis inhibitor

d)

D. Nucleic acid synthesis inhibitor

e)

E. Alkylating agent

23.

The compound use to identify the partition coefficient in-vitro

a)

A. Tert-butyl alcohol

b)

B. Phenol

c)

C. Isopentyl alcohol

d)

D. N-octanol

e)

E. Benzyl alcohol

24.

Isoniazid is metabolized by human principally by

a)

A. acetylation

b)

B. Deamination

c)

C. Methylation

d)

D. Conjugation

e)

E. Oxidation

25.

The total affinity of the ligand to its receptor

a)

A. Intrinsic activity

b)

B. Agonist activity

c)

C. Avidity

d)

D. Antagonistic activity

e)

E. Agonistic activity

26.

Dimethylbenzene is also known as

a)

A. anisole

b)

B. aniline

c)

C. Xylene

d)

D. Phenol

e)

E. Ethylene

27.

This compound is derived from the destructive distillation of castor oil and it is use as a keratolytics agent

a)

A. Salicylic acid

b)

B. Undecylanic acid

c)

C. Benzoic acid

d)

D. Chrysarobin

e)

E. Propionic acid

28.

The following are example of G Protein coupled receptor exept.

a)

A. GABA receptors

b)

B. Beta 2 Receptors

c)

C. Muscarinic receptors

d)

D. Alpha-1 receptor

29.

DNA alkylating agent binds to its target by means of what bond?

a)

A. Hydrogen bonding

b)

B. Electrostatic bonding

c)

C. Hydrophobic bonding

d)

Ionic bonding

e)

E. Covalent bonding

30.

A long-acting HMG-CoA reductase inhibitor

a)

A. Rosuvastatin

b)

B. Lovastatin

c)

C. Fluvastatin

d)

D. Simvastatin

e)

E. Pravastatin

31.

A theory that advances that idea that maximum pharmacologic effects can be obtaimed if all the receptor are occupied

a)

A. Hypothesis of paton

b)

B. lock and key theory

c)

C. Hypothesis of clark

d)

D. Induced fit theory

e)

E. Hyphothesis of ariens & stephenson

32.

The anti-angina effects of nitrates is primarily due to the release of what gas

a)

A. Nitrous oxide

b)

B. Dinitrogen oxide

c)

C. Nitrogen dioxide

d)

D. Nitric oxide

e)

Dinitrogen dioxide

33.

Diuretic that acts on the distal convoluted tubule

a)

A. indapamide

b)

B. Furosemide

c)

C. Ethacrinic

d)

D. Acezolamide

e)

E. Spironolactone

34.

what is 1,4-dihydroxybenzene?

a)

A. Catechol

b)

B. Phenol

c)

C. Xylene

d)

D. Hydroquinone

e)

E. El Resorcinol

35.

Halogenation of alkanes is posible in what type of reaction?

a)

A. Substitution

b)

B. Elimination

c)

C. Radical reactions

d)

D. Addition

e)

E. Combustion

36.

Alkylation of aminobenzene will likely proceed to what position?

a)

A. ortho position

b)

B. Meta position

c)

C. Para position

d)

D. Both A and B

e)

E. Both A and C

37.

This is a derivative of two carboxylic acids, in which the compound is formed by the removal of one molecule of water in two RCOOH

a)

A. Ether

b)

B. Acid Anhydride

c)

C. Amide

d)

D. Acyl halide

e)

E. ester

38.

what substance may be used to clean a glass apparatus which is particularly greasy?

a)

A. Nitric acid

b)

B. Concentrated hydrochloric acid

c)

C. Chromosulfuric acid

d)

D. Hypochlorous acid

e)

E. Sulfuric acid

39.

what is the color imparted by calcium chloride to the flame viewed through cobalt glass?

a)

A. Crimson red

b)

B. Light green

c)

C. Intense yellow

d)

D. Nill

e)

E. Brick red

40.

1 alkaloids often occur in plants in association with a characteristic acid, this is specific acid in which opium alkaloids are commonly associated

a)

A. Cinchotannic acid

b)

B. Meconic acid

c)

C. Quinic acid

d)

D. Shikimic acid

e)

E. Tartaric acid

41.

The tropic acid fragment of tropane alkaloids like hyoscine and hyoscyamine is derived from this specific amino acid

a)

A. alanine

b)

B. Glycine

c)

C. Phenylalanine

d)

D. Proline

e)

E. Tyrosine

42.

This in the basic moiety of cocaine alkaloids

a)

A. Cinnamylcocaine

b)

B. Egconine

c)

C. Truxillic acid

d)

D. all

e)

E. none

43.

The following alkaloids are classified heterocyclic alkaloids, except

a)

A. Arecoline

b)

B. Cocane

c)

C. Colchicine

d)

D. Lobeline

e)

E. Quinine

44.

The following active principles isolated from plants exhibit haemolytic property except

a)

A. Arbutin

b)

B. Glycyrrhizin

c)

C. Senegin

d)

D. A-solanin

e)

E. Tomaatin

45.

The following statements are incorrect about methyl salicylate

a)

it is obtained by maceration and subsequent steam distillation of Gaulteria leaves

b)

B. it is made synthetically by distilling a mixture of ethanol and saligenin

c)

C. A colerless, pink to purple liquid with odor and taste of wintergreen

d)

D. A and B

e)

E. B and C

46.

A resin which is used as stiffening agent in cerates, plasters and ointments and as adulterant of other resinous products

a)

A. podophyllum

b)

B. Mastic

c)

C. Eriodictyon

d)

D. jalap

e)

E. Rosin

47.

The following indole alkaloids were isolated from plants belonging to family apocynaceace

a)

A. Reserpine

b)

B. Physostigmine

c)

C. Vinblastine

d)

D. Vincristine

e)

E. Yohimbine

48.

The chief enzyme responsible for the hydrolysis of gaultherin and the production of methyl salicylate

a)

A. Amylase

b)

B. Glucosidase

c)

C. Gaultherase

d)

D. Emulsion

e)

E. Myrosin

49.

A resin derived from the tuberous root of exogonium purga which used as cathartic agent

a)

A. Podophyllum

b)

B. Mastic

c)

C. Eriodictyon

d)

D. Jalap

e)

E. Rosin

50.

The drying fixed oils expressed from carthamus tinctorius and is recommended for its cholesterol lowering properties

a)

A. Olive oil

b)

B. Palm oil

c)

C. Linseed oil

d)

D. Safflower oil

e)

E. Sesame oil

51.

The Alkaloidal precipitating reagent which is composed of saturated solution of picric acid

a)

A. Hager's reagent

b)

B. Dragendorff's reagent

c)

mayer's reagent

d)

D. Wagner's reagent

e)

E. Sonnenschein reagent

52.

The sedating principles isolated from the cannabis resin are

a)

A. Cannabidiol

b)

B. Cannabichromene

c)

C. Cannabidiolic acid

d)

D. A and B

e)

E. B and C

53.

The ginger volatile of consists of the following sesquiterpenes

a)

A. Bisaboline

b)

B. Zingiberene

c)

C. Zingerone

d)

D. Zingiberol

e)

E. None

54.

Alkaloids react with wagner's and dragendorffs's reagent and will form precipitate which are colored

a)

A. Cream

b)

B. Yellow

c)

C. Black

d)

D. Reddish Brown

e)

E. Blue

55.

The following are medicinal uses of balsam of copaiba except

a)

A. Diuretic

b)

B. Expectorant

c)

C. Genitourinary disenfectant

d)

D. Astringent

e)

E. Laxative

56.

The following are tribasic acids which are important components of the kreb's cycles except

a)

A. Aconitoc acid

b)

B. Citric acid

c)

C. Malic acid

d)

D. Isocitric acid

e)

E. None

57.

Which among the following balsams is commonly used for skin diseases and as a local protectant?

a)

A. Balsam of copaiba

b)

B. Peru balsam

c)

C. Benzoin

d)

D. Tolu balsam

e)

E. Storax

58.

A leading cause of blindness, which ia due to overtime,oxidative damage to the retinal pigment epithelium, such as that the brain no longer processes light correctly

a)

A. macular degeneration

b)

B. Astigmatism

c)

C. Diplopia

d)

D. Nearsightedness

e)

E. Farsightedness

59.

The following are non-enzymatic antioxidants (free-radical scavengers), except:

a)

A. Vitamin E

b)

B. Vitamin C

c)

C. Carotenoids

d)

D. Flavonoids

e)

E. Vitamin K

60.

The most potent ROS

a)

A. Hydrogen Peroxide

b)

B. Hydroxyl radical

c)

C. Superoxide

d)

D. Coenzyme Q

e)

E. Nitric oxide

61.

Metformin is the standard first-line oral medication for type 2 diabeties. the use of the drug has the potential side affect of lactic acidoses. which of the following explains why this lactic acid buildup is rarely seen clinically

a)

A. The red blood cell utilize the lactate as fuel

b)

B. The renal cells utilizes lactate as fuel

c)

C. The cardiac muscle cells utilize the lactate as fuel

d)

The Large, voluntary muscle group utilize the lactase as fuel

62.

A contestant on a TV reality show, in which the contestants had to survive off the land for an extended period of time, developed recurrent diarrhea, dermatitis and had trouble remembering things. These symptoms could be brought about due to the lack of which one of the following in the contestant's diet?

a)

A. Niacin

b)

B. Thiamine

c)

C. Riboflavin

d)

D. Vitamin C

e)

E. Vitamin D

63.

The following contains glucose, except:

a)

A. Glycogen

b)

B. Triacyglycerol

c)

C. Glycoprotein

d)

D. Glycolipid

e)

E. Ceramide

64.

which is true regard to digestion of biomolecules?

a)

A. Protein digestion starts in the mouth

b)

B. Carbohydrate digestion begins in the stomach

c)

C. Lipid digestion begins in the stomach

d)

D. A and B

e)

E. B and C

65.

Aspirin-induced asthma (AIA) is a severe action to nonsteroidal anti-inflammatory drugs (NSAIDs) characterized by bronchoconstriction 30 minutes to several hours after ingestion. It is seen in as many as 20% of adults. Which of the following statements best explains the symptoms seen in patients with AIA?

a)

A. NSAIDs inhibit the activity of the CFTR protein, resulting in thickened secretions that block airways.

b)

B NSAIDs inhibit COX but not lipoxygenase, resulting in the flow of arachidonic acid to leukotriene synthesis.

c)

C. NSAIDs activate the COX activity of PGH synthase, resulting in increased synthesis of prostaglandins that promote vasodilation.

d)

D. NSAIDs activate phospholipases, resulting in decreased amounts of and alveolar dipalmytoylphosphatidylcholine collapse.

e)

E. NSAIDs inhibit both COX and LOX enzyme and the asthma attack is due to allergic response to various antigens

66.

The following are true about cholesterol, except

a)

A. Cholesterol is a stuctural component of all cell membranes

b)

B. Choleaterol is a precursor of bile acids and vitamin C

c)

Liver plays a central role in the regulation of the body's cholesterol homeostasis

d)

D. cholesterol is the major sterol in animal tissues

e)

E. all of these

67.

what anti-obesity agent inhibits both gastric and pancreatic lipases?

a)

A. Colestipol

b)

B. Simvastatin

c)

C. Orlistat

d)

D. Niacin

e)

Gemifibrozil

68.

What is the rate-limiting enzyme and the major control point for cholesterol biosynthesis?

a)

A. HMG CoA reductase

b)

B. Decarboxylase

c)

C. Kinase

d)

D. Transferase

e)

E. Isomerase

69.

Cholelithiasis is a:

a)

A. kidney failure condition

b)

B. Cholesterol storage disease

c)

C. Cholesterol gallstone disease

d)

Cholesterol degradation failure

e)

E. Heart Problem

70.

That jas been employed to study cerebral physiology and is has found increased use in cancer diagnos and management

a)

A. Nuclear magnetic resonance (NMR)

b)

B. Positron emission tomography (PET)

c)

C. Single-photon emission computed tomography (SPECT)

d)

D. Medical Ultrasonography

e)

E. Computerized tomography (CT) scan

71.

In what proportion should 5% and 1 % ointment be mixed to prepare a 3% ointment with the same active ingredient?

a)

A. 1:10

b)

B. 1:1

c)

C. 2:3

d)

D. 1:5

e)

E. 3:5

72.

A patient maintained on warfin was given a prescription for clarithromycin for an upper respiratory tract infection. which of the following statement is true?

l. The prescriber needs to be inform that the patient is on warfin therapy

ll. clarithromycin inhibits the metabolism of warfin which could lead bleeding

lll. There is no need to contact the prescriber, it is safe to take both medications together.

a)

A. l only

b)

B. lll only

c)

C. l and ll

d)

D. ll and lll

73.

The microorganism that is identified by Quellung reaction, the capsule swelling test.

a)

A. Streptococcus agalactiae

b)

B. Enterococci

c)

C. Streptococcus pyogenes

d)

D. Streptococcus pneumoniae

e)

E. Streptococcus anginosus

74.

Prions usually cause " transmissible spongiform encephalopathies, this is manifest in humans as

a)

A. Scrapie disease

b)

B. Creutzfeldt-Jakob disease

c)

C. Madcow disease

d)

D. All of these

e)

E. None of these

75.

A patient who is taking methadone to manage pain from a sports injury continues to drink grape fruit juice. what could happen to this patient?

l. No effect on the patient

ll. Failure of the therapy of pain medication

lll. May experience toxicity due to methadone

a)

A. l only

b)

B. lll only

c)

C. l and ll

d)

D. ll and lll

e)

E. l, ll and lll

76.

A common side effect of nitrates

a)

A. Hypertension

b)

B. Headaches

c)

C. Dry cough

d)

D. Bronchospasm

e)

E. Vasoconstriction

77.

In what proportion should a 10% zinc oxide ointment be mixed with with petrolatum to come up with a 2% zinc oxide ointment?

a)

A. 5:1

b)

B. 1:4

c)

C. 2:3

d)

D. 1:10

e)

E. 2:5

78.

Determine the specific gravity of a mixture containing the following:

1000 mL water

750 mL glycerin (sp.gr. 1.25)

1259 mL alcohol (sp.gr. 0.81)

a)

A. 2.06

b)

B. 3.06

c)

C. 1.3

d)

D. 0.75

e)

E. 0.98

79.

Which of the following describes 2nd generation H¹- antihistamines?

a)

A. Example of 2nd generation antihistamines include chlorpheniramine and cyclizine

b)

B. Common effect of first-generation H¹- antagonists is sedation

c)

C. Some 2nd generation H¹ antihistamines possesess serotonin-blocking adrenoreceptor blocking action

d)

D. Second-generation H¹ antihistamines are used mainly for the treatment of allergic rhinitis and chronic urticaria

e)

E. 2nd generation H¹ antihistamines are less expensive compared to 1st gen H¹ antihistamines

80.

The co-administration of MAO inhibitors with SSRIs is Contraindicated because

a)

A. The combination will decrease the effect of MAO inhibitors

b)

B. The combination will decrease the effect of SSRIs

c)

C. The patient will be more depressed

d)

D. The combination could cause serotonin syndrome

e)

E. None of these

81.

Which of the following is/are TRUE regarding the use of MAO inhibitors and SSRIs?

l. These could be given together safely

ll. A wash out period of at least 2 weeks is necessary before the other type is administered

ll. Fluoxetine should be discontinued at least 16 weeks before a MAOI is initiated

a)

A. l only

b)

B. lll only

c)

C. l and ll

d)

D. ll and lll

e)

E. l,ll and lll

82.

The drug interaction between levodopa and phenelzine could result to which of the following

a)

A. Seratonin syndrome

b)

B. Hypertensive crisis

c)

C. Hyperthyroidism

d)

D. Hyperthermia

e)

E. None of these

83.

A patient requires 1500 kcal/day, including 50g of protein. determine the number of kcal provided by the protein

a)

A. 200 kcal

b)

B. 400 kcal

c)

C. 600 kcal

d)

D. 800 kcal

e)

E. 100 kcal

84.

Determine the following for a patient's enteral nutrition:

Grams of dextrose, 100 g protein: 100 g lipid

Gram of protein to supply 800 kcal

Grams of lipid to supply 900 kcal

a)

A. 400 g dextrose, 100 g protein: 100 g lipid

b)

B. 350 g dextrose, 250 g protein: 150 g lipid

c)

C. 100 g dexrose, 800 g protein: 900g lipid

d)

D. 375 g dextrose, 200 g protein: 100 g lipid

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