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WorksheetsChemo-Induced Nausea & Vomiting (CINV) Quiz
Total questions: 29
Worksheet time: 15mins
What is the role of the chemoreceptor trigger zone in CINV?
It is activated by various neurotransmitters and mediates nausea and vomiting.
It produces red blood cells.
It regulates blood pressure.
It controls heart rate.
Which of the following is NOT a type of nausea and vomiting (N/V) associated with chemotherapy?
Anticipatory
Acute
Chronic
Delayed
Delayed nausea and vomiting is defined as:
N/V before chemotherapy
N/V less than 24 hours after chemotherapy
N/V more than 24 hours after chemotherapy
Uncontrolled N/V
What is breakthrough nausea and vomiting?
N/V despite prevention
N/V before chemotherapy
N/V more than 24 hours after chemotherapy
Uncontrolled N/V
Which type of nausea and vomiting is described as uncontrolled?
Refractory
Acute
Delayed
Anticipatory
Which of the following is a correct pairing of type and timing of N/V?
Acute: < 24 hours after chemo
Delayed: before chemo
Anticipatory: > 24 hours after chemo
Breakthrough: before chemo
Neurokinin (NK1) is involved in which process?
Activation of the chemoreceptor trigger zone
Red blood cell production
Muscle contraction
Bone growth
Which neurotransmitter is abbreviated as 5-HT3?
Serotonin
Dopamine
Histamine
Acetylcholine
Which of the following is NOT a neurotransmitter mentioned in the context of CINV?
Acetylcholine (ACh)
Histamine (H1)
Dopamine (DA)
Adrenaline (AD)
What does "breakthrough" N/V refer to?
N/V despite prevention
N/V before chemo
N/V more than 24 hours after chemo
Uncontrolled N/V
Which type of N/V is associated with expectation before chemotherapy?
Anticipatory
Acute
Delayed
Refractory
Which of the following is a correct description of refractory N/V?
Uncontrolled N/V
N/V before chemo
N/V < 24 hours after chemo
N/V > 24 hours after chemo
Which of the following is a receptor involved in the activation of the chemoreceptor trigger zone?
5-HT3
GABA
Insulin
Glutamate
Which of the following is a correct description of anticipatory N/V?
N/V before chemo because you expect it to happen
N/V < 24 hours after chemo
N/V > 24 hours after chemo
Uncontrolled N/V
Which medication is used as a single drug option for delayed (Day 2-4) treatment in moderate risk emetogenic chemotherapy?
Dexamethasone (Dexa)
Olanzapine + dexa
5-HT3 + dexa
NK₁ + 5-HT3
What is the recommended approach for minimal risk (<10%) emetogenic chemotherapy?
No antiemetic needed
5-HT3 + dexa
NK₁ + 5-HT3 + dexa
Olanzapine + dexa
Which of the following is NOT a low-risk (10-30%) antiemetic option?
Olanzapine
Dexamethasone
5-HT3
Metoclopramide
Which of the following is a 5-HT3 receptor antagonist?
Ondansetron
Aprepitant
Olanzapine
Dexamethasone
Which medication is known to cause CNS depression, anticholinergic effects, and metabolic changes?
Olanzapine
Ondansetron
Aprepitant
Fosaprepitant
Which medication should be avoided IV/IM in children under 2 years due to tissue damage?
Promethazine
Metoclopramide
Olanzapine
Ondansetron
What is the black box warning (BW) for metoclopramide?
Tardive dyskinesia
QT prolongation
Serotonin syndrome
Neutropenia
Which of the following is NOT a route of administration for granisetron?
PO/IV/SubQ/transdermal
IM only
PO only
IV only
Which antiemetic is associated with the risk of QT prolongation?
Olanzapine
Aprepitant
Fosaprepitant
Metoclopramide
Which medication is NOT recommended for use in children under 2 years?
Promethazine
Ondansetron
Dexamethasone
Aprepitant
Which antiemetic is a miscellaneous agent with an unknown antiemetic mechanism of action?
Dexamethasone
Ondansetron
Aprepitant
Granisetron
Which antiemetic may decrease the efficacy of contraception?
Fosaprepitant
Olanzapine
Metoclopramide
Promethazine
Which medication is NOT a 5-HT3 receptor antagonist?
Aprepitant
Ondansetron
Granisetron
Palonosetron
Which antiemetic is associated with fatigue, neutropenia, and hypotension?
Aprepitant
Ondansetron
Olanzapine
Metoclopramide
Which antiemetic is available as both PO and IM/IV formulations?
Metoclopramide
Aprepitant
Palonosetron
Fosaprepitant
