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WorksheetsSexual Andrology
Total questions: 30
Worksheet time: 15mins
A 28-year-old man with Kallmann syndrome is treated with hCG and FSH injections over two years. His serum testosterone and FSH levels are normal. His semen volume is 1.0 mL, sperm count is six million sperm/mL, and sperm motility is 90%. Well-timed sexual intercourse has not resulted in pregnancy for his wife, whose evaluation is normal. The next step is:
Intrauterine insemination
Color Doppler scrotal ultrasound
ICSI
TRUS
Testis biopsy
A 45-year-old man presents with primary infertility. Physical examination shows small testes, bilateral gynecomastia, and decreased body hair. Semen analysis reveals azoospermia. Serum FSH and LH are elevated, and testosterone is low. The most likely diagnosis is:
Kallmann syndrome
Androgen insensitivity syndrome
Hypogonadotropic hypogonadism
Klinefelter syndrome
Y chromosome microdeletion
In men, testosterone therapy can lead to all of the following EXCEPT:
Decreased sperm production
Increased hematocrit
Increased spermatogenesis
Gynecomastia
Decreased intratesticular testosterone
Which of the following is the most common cause of erectile dysfunction in men over 50 years old?
Psychogenic factors
Hypogonadism
Vascular disease
Neurologic disease
Peyronie's disease
A 35-year-old man presents with infertility. Semen analysis shows normal volume, azoospermia, and low FSH. Which of the following is the most likely cause?
Klinefelter syndrome
Sertoli cell-only syndrome
Obstructive azoospermia
Mumps orchitis
Y chromosome microdeletion
The first-line therapy for premature ejaculation is:
Sildenafil
Tadalafil
SSRIs (e.g., dapoxetine, paroxetine)
Intracavernosal injection
Vacuum erection device
Which of the following semen parameters is LEAST affected by varicocelectomy?
Sperm count
Sperm motility
Semen volume
Sperm morphology
Total motile count
Which of the following is the most common structural abnormality in men with congenital bilateral absence of the vas deferens?
Bilateral renal agenesis
Unilateral renal agenesis
Horseshoe kidney
Polycystic kidney disease
Multicystic dysplastic kidney
A patient with erectile dysfunction is found to have low testosterone on two morning serum measurements. LH is elevated. The next step is:
Testicular ultrasound
Testosterone replacement therapy
MRI of pituitary
Semen analysis
Karyotype analysis
Which of the following is most likely to improve erectile function in a man with type 2 diabetes and ED?
Tight glycemic control alone
Vacuum erection device only
PDE5 inhibitor therapy
Penile prosthesis as first-line
Intracavernosal papaverine alone
The first-line pharmacologic treatment for premature ejaculation is:
Sildenafil
Tadalafil
Selective serotonin reuptake inhibitors
Intracavernosal injection
Vacuum erection device
A patient with erectile dysfunction is started on sildenafil. The primary mechanism of action of sildenafil is:
Nitric oxide donor
Guanylate cyclase inhibitor
Phosphodiesterase type 5 inhibitor
Acetylcholinesterase inhibitor
Beta-adrenergic blocker
A 32-year-old man with azoospermia has small testes and elevated FSH. The most likely diagnosis is:
Obstructive azoospermia
Klinefelter syndrome
Pituitary adenoma
Hypogonadotropic hypogonadism
Y chromosome microdeletion
The most common side effect of intracavernosal injection therapy for erectile dysfunction is:
Priapism
Corporal fibrosis
Penile pain
Infection
Hematoma
Which of the following is a contraindication to testosterone replacement therapy?
Type 2 diabetes
Osteoporosis
Desire for fertility
History of kidney stones
Obstructive sleep apnea
A patient with congenital bilateral absence of the vas deferens should have which additional evaluation?
Renal ultrasound
Cystoscopy
Scrotal ultrasound
Transrectal ultrasound
Karyotype
The most common complication of penile prosthesis implantation is:
Cylinder leakage
Infection
Mechanical failure
Penile shortening
Urethral erosion
Which of the following semen parameters is most predictive of natural conception?
Sperm concentration
Sperm motility
Sperm morphology
Semen volume
pH
The recommended first-line therapy for erectile dysfunction in a patient with diabetes is:
Penile prosthesis
Vacuum erection device
PDE5 inhibitor
Intracavernosal injection
Psychosexual counseling
Which of the following is the most common cause of primary hypogonadism in men?
Kallmann syndrome
Klinefelter syndrome
Testicular trauma
Mumps orchitis
Cryptorchidism
Male factors associated with an increase of SHBG circulating levels are all, EXCEPT:
Hyperthyroidism
Aging
AIDS/HIV
Cushing disease
Based on 2nd and 3rd Princeton Consensus, intermediate cardiac risk patients with erectile dysfunction include patients with:
Recent myocardial infarction less than 2 weeks ago
Recent myocardial infarction between 2 to 6 weeks ago
Myocardial infarction more than 6 weeks ago
Uncomplicated previous myocardial infarction
Topical alprostadil is currently approved at the dose of:
100 μg
200 μg
300 μg
400 μg
Which statement regarding the treatment of erectile dysfunction is correct?
Sildenafil is effective 10-20 minutes after administration
Efficacy of Tadalafil is maintained for up to 24 hours
Efficacy of Vardenafil is reduced by a heavy, fatty meal
Avanafil dosage should be adapted based on renal function, hepatic function, age or gender
Which phosphodiesterase inhibitor is associated with the highest PDE selectivity for PDE5 over PDE6?
Sildenafil
Tadalafil
Vardenafil
Avanafil
One of the purposes of The International Index of Erectile Function questionnaire is to:
Define the aetiology of erectile dysfunction
Determine the type of erectile dysfunction
Detect the risk factors of erectile dysfunction
Monitor the response to treatment
Which is an absolute contraindication for intracavernosal alprostadil therapy in erectile dysfunction treatment?
Diabetes mellitus
Anticoagulant use
Peyronie's disease
History of ischemic priapism
Which is the most common postoperative complication of grafting procedures for Peyronie's disease treatment?
Erectile dysfunction
Penile shortening
Poor cosmetic result
Urethral injury
Which of the following is NOT a recognised treatment for premature ejaculation?
Dapoxetine
Phosphodiesterase-5 inhibitors
Phenylephrine
Tramadol
What is the prevalence of testicular microcalcification in men referred for testicular ultrasound?
1-10%
0-1%
10-25%
25-50%
