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WorksheetsGenetics Unit 1
Total questions: 75
Worksheet time: 38mins
The different forms of a gene
alleles
atoms
proteins
wheels
A chart that shows all the possible combinations of alleles that can result from a genetic cross
dominant allele
codominance
probability
Punnett Square
An organism's physical appearance or visible traits. (what it looks like)
phenotype
genotype
B = brown fur b = white fur
In the Punnett square, what is the probability for white fur?
0%
25%
50%
75%
Which of the following is NOT one of Mendel’s Laws?
Law of Segregation
Law of Independent Assortment
Law of Linkage
Law of Dominance
In humans, dosage compensation of X-linked genes is achieved through:
a) Gene duplication
b) X-inactivation (Lyon hypothesis)
c) Methylation of Y chromosome
d) Multiple allelism
A physical appearance is
genotype
heterozygous
phenotype
codominance
In a Punnett square, a lower case letter stands for a ____________ allele.
dominant
recessive
homozygous
heterozygous
Which mechanism is involved in epigenetics?
a) Mutation in DNA
b) Histone modification and DNA methylation
c) Gene duplication
d) Translocation of chromosomes
The physical location of a gene on a chromosome is called:
a) Gene expression site
b) Locus
c) Allele
d) Chromatid
Crossing over occurs during which stage of meiosis?
a) Prophase I (Pachytene)
b) Metaphase I
c) Anaphase I
d) Telophase I
The unit of genetic distance used in mapping is:
a) Morgan unit
b) Centimorgan (cM)
c) Base pair (bp)
d) Karyotype unit
Somatic cell hybridization often uses:
a) HAT selection medium
b) Nutrient agar
c) SDS-PAGE
d) Gel electrophoresis
A 9:3:4 phenotypic ratio indicates:
a) Complementary gene interaction
b) Duplicate genes
c) Recessive epistasis
d) Dominant epistasis
Which one is an example of sex-linked inheritance?
a) Sickle cell anemia
b) Color blindness
c) ABO blood group
d) Polydactyly
Cytoplasmic inheritance is also known as:
a) Nuclear inheritance
b) Maternal inheritance
c) Paternal inheritance
d) Epigenetic inheritance
Linkage was first discovered in:
a) Pea plants
b) Drosophila melanogaster
c) Maize
d) Yeast
Which chromosome structure is found in amphibian oocytes and used for active transcription studies?
a) Polytene chromosome
b) Lampbrush chromosome
c) Metacentric chromosome
d) Telocentric chromosome
Somatic cell hybridization is useful for:
a) Gene therapy
b) Assigning genes to chromosomes
c) Producing hybrids between species
d) Both (b) and (c)
Who is regarded as the "Father of Linkage and Crossing Over"?
(a)
Erythroblastosis fetalis (Hemolytic disease of newborn) occurs when:
a) Mother is Rh⁺ and fetus is Rh⁻
b) Mother is Rh⁻ and fetus is Rh⁺
c) Both are Rh⁺
d) Both are Rh⁻
The Rh factor in humans is due to:
a) Genes located on X chromosome
b) Genes located on chromosome 1
c) Genes located on chromosome 9
d) Genes located on chromosome 14
2.Codominance is characterized by
a.intermediate expression
b.blending of traits
c.simultaneous expression
both b and c
4.The multiple phenotypic expression of a single gene is referred to as (a) .
8.State true or false: Variations in phenotype among individuals of a species may be due to genetical or environmental differences but not both.
True
False
14.The gene that is being suppressed during inter genic interaction is known as (a) gene.
15.Presence of recessive alleles at both gene loci and presence of dominant allele at the hypostatic locus produce the same phenotype. What type of interaction is seen in this case?
Incomplete dominance
Dominant epistasis
Codominance
Recessive epistasis
In summer squash if you cross different varieties of true breeding sphere shaped squash, you get a disk shaped progeny. What phenomenon is seen here?
Gene interaction
Epistasis
Multiple allele
Codominance
Two pairs of non-allelic dominant genes which interact to produce one phenotype is
Complementary genes
Supplementary genes
Epistasis
Dihybrid cross
The gene that masks or suppresses other gene is called
Epistasis
Hypostatic
Epistatic
Complementary genes
What does autosomal mean?
Relating to a gene on a sex chromosome
A chromosome disorder
Relating to a gene on a chromosome that is not a sex chromosome
Chromosomes with the same genes
What does pleiotropy mean?
One gene controlling multiple traits
One gene controlling one trait
One gene that does not control any trait
Multiple genes that control one trait
What does sex-linked refer to?
A gene that exists on a chromosome
A gene that does not differ in inheritance patterns between sexes
A gene that is on an autosomal chromosome
A gene that is on a sex chromosome
What does codominance mean?
Do not pick this one :(
Where the phenotype of the heterozygote is an intermediate of the two homozygote phenotypes
Where the heterozygote shows both the phonotypes of the homozygotes simultaneously
Where the heterozygote has the same phenotype as one of the homozygotes
What does epistasis mean?
More than one gene controlling more than one trait
One gene controlling more than one trait
More than one gene controlling one trait
One gene controlling one trait
If a gene controlling flower color showed incomplete dominance what would the offspring of the cross between a red flower and white flower look.
Pink
Red
White
Red and white
If a gene controlling flower color was completely dominant what would the offspring of the cross between a red flower and white flower look. Red is dominant to white.
Red and white
Red
white
Pink
If a gene controlling flower color showed codominance what would the offspring of the cross between a red flower and white flower look.
White
Red
Red and white
Pink
Persons having genotype IAIB would show the blood group AB. This is because of
Pleiotropy
Co-dominanace
Segregation
Incomplete dominanace
All genes located on the same chromosome
forms different groups depending upon their relative distance
form one linkage group
will not form any linkage groups
forms interactive group that affect the phenotype
In a dihybrid cross if you get 9:3:3:1 ratio, it denotes that
The alleles of two genes are interacting with each other
Its multigenic inheritance
It exhibits multiple allelism
The alleles of two genes are segregating independently
Ocassionally a single gene may express more than one effect. This phenomenon is called
multiple allelism
mosaicism
pleiotropy
polygeny
In a marriage between male with blood group A and female with blood group B, the progeny had either blood group AB or B. What could be the possible genotype of parents?
IA i (Male) ; IB i (Female)
IA i (Male) ; IB IB(Female)
IAIA(Male) ; IBIB (Female)
IA IA (Male) ; IB i (Female)
_________ is called null allele
IA
IB
IO
none of these
ABO blood group in man is controlled by
multiple allele
lethal gene
sex linked genes
Y linked genes
If the child's blood group is O, father's blood group is A and mother's blood group is B. then the genotype of the parents will be
IA IA and IB IO
IA Io and IB IO
IA IO and IO IO
IO IO and IB IB
Inheritance of ABO blood group system is an example of
(a) dominance
(b) epistasis
(c) partial dominance
(d) multiple allelism
A person with antigens A and B and no antibodies belongs to blood group or in which blood group antibodies are absent
(a) O
(b) AB
(c) B
(d) A
This is the genotype of blood group A
(a) IA IA
(b) IA IO
(c) IB IB
(d) IA IA or IA IO
ABO blood groups in humans are controlled by the gene I. It has three alleles – IA, IB and I. Since there are three different alleles, six different genotypes are possible. How many phenotypes can occur?
a) Three
b) One
c) Four
d) Two
1. The term used to describe the number of chromosomes in an egg or sperm cell is
A. diploid
B. gamete
C. haploid
D. zygote
8. The diagram shows the chromosomes from one person.
What can be deduced about the person who has these chromosomes?
A. a female with Down’s syndrome
B. a male with Down’s syndrome
C. a normal female
D. a normal male
11. Gametes are produced by the process of ------------
A. mitosis
B. meiosis
C. crossing-over
D. replication
12. Chromosomes that determine the body characteristics -------------------------------
A. Allosomes
B. Autosomes
C. Karyotype
D. Sex linkage
Which of the following is an example of a sex-linked recessive disorder found on the X chromosome?
Huntington's disease
Duchenne muscular dystrophy
Cystic fibrosis
Red-Green Color blindness
What genotype should be placed in the box with a question mark?
XHXh
XHXH
XhY
XHY
What percentage of the offspring could be colorblind?
0%
What gender of the offspring will be colorblind?
male
female
What percentage of the offspring could have normal vision?
Which genotype represents a female who is a carrier for hemophilia?
The study of the inherited changes in gene expression that occur without a change in gene sequence and influence how an organism's genes express themselves. Mechanisms are influenced by food and environment. They play an important role in the fetal basis of adult disease susceptibility.
bionomics
genomics
genetics
epigenetics
Protein molecules around which DNA is tightly coiled in chromatin
histones
casein
nucleosome
chromosome
A chemical modification of DNA that does not affect the nucleotide sequence of a gene but makes that gene less likely to be expressed.
activators
methylation
acetylation
proteins
How can a person's muscle cells have the same exact DNA sequences as their nerve cells even though the look and perform completely different?
The two different cells become mutated
They actually have different DNA in the two types of cells.
The proteins expressed in each cell are different
The genome of the different cells changes
What is a Gene?
A segment of DNA that encodes for a protein
A segment of RNA that encodes for a protein
Chromosome
chromatin
Epigenetics refers to changes in:
DNA sequence
Gene structure
Gene expression
DNA frequency
In terms of epigenetics, acetylated histones usually result in which of the following?
Increase in transcription/ gene expression
Decrease in transcription/ gene expression
Increase in DNA - lamina association
Decrease in DNA - lamina association
Euchromatin ...
genetically active
Genetically inactive
condensed
present in both prokaryotes and eukaryotes
Heterochromatin ...
genetically active
present only in eukaryotes
present in both prokaryotes and eukaryotes
consists of less amount of DNA
A group of genes that are regulated together is called a(n)
operator
promoter
operon
repressor
The study of changes in organisms caused by modification of gene expression rather than alteration of the genetic code itself
hypogenomics
epigenetics
microgenomics
none of these
Epigenetics refers to changes in:
DNA sequence
Gene structure
Gene expression
DNA frequency
