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Genetics Unit 1

Total questions: 75

Worksheet time: 38mins

Name
Class
Date
1.
An organism that has two identical alleles for a trait is said to be what?
a)
Hybrid
b)
Co-dominant
c)
Homozygous
d)
Heterozygous
2.
An organism that has two different alleles for a trait is?
a)
Hybrid
b)
Co-Dominant
c)
Homozygous
d)
Heterozygous
3.
Whos discoveries set the foundation for the study of genetics?
a)
Oliver
b)
Taylor
c)
Mendel
d)
Newton
4.

The different forms of a gene

a)

alleles

b)

atoms

c)

proteins

d)

wheels

5.

A chart that shows all the possible combinations of alleles that can result from a genetic cross

a)

dominant allele

b)

codominance

c)

probability

d)

Punnett Square

6.

An organism's physical appearance or visible traits. (what it looks like)

a)

phenotype

b)

genotype

7.

B = brown fur b = white fur

In the Punnett square, what is the probability for white fur?

a)

0%

b)

25%

c)

50%

d)

75%

8.

Which of the following is NOT one of Mendel’s Laws?


a)

Law of Segregation

b)

Law of Independent Assortment

c)

Law of Linkage

d)

Law of Dominance

9.

In humans, dosage compensation of X-linked genes is achieved through:


a)

a) Gene duplication

b)

b) X-inactivation (Lyon hypothesis)

c)

c) Methylation of Y chromosome

d)

d) Multiple allelism

10.

A physical appearance is

a)

genotype

b)

heterozygous

c)

phenotype

d)

codominance

11.

In a Punnett square, a lower case letter stands for a ____________ allele.

a)

dominant

b)

recessive

c)

homozygous

d)

heterozygous

12.

Which mechanism is involved in epigenetics?


a)

a) Mutation in DNA

b)

b) Histone modification and DNA methylation

c)

c) Gene duplication

d)

d) Translocation of chromosomes

13.

The physical location of a gene on a chromosome is called:



a)

a) Gene expression site

b)

b) Locus

c)

c) Allele

d)

d) Chromatid

14.

Crossing over occurs during which stage of meiosis?



a)

a) Prophase I (Pachytene)

b)

b) Metaphase I

c)

c) Anaphase I

d)

d) Telophase I

15.

The unit of genetic distance used in mapping is:



a)

a) Morgan unit

b)

b) Centimorgan (cM)

c)

c) Base pair (bp)

d)

d) Karyotype unit

16.

Somatic cell hybridization often uses:


a)

a) HAT selection medium

b)

b) Nutrient agar

c)

c) SDS-PAGE

d)

d) Gel electrophoresis

17.

A 9:3:4 phenotypic ratio indicates:


a)

a) Complementary gene interaction

b)

b) Duplicate genes

c)

c) Recessive epistasis

d)

d) Dominant epistasis

18.

Which one is an example of sex-linked inheritance?


a)

a) Sickle cell anemia

b)

b) Color blindness

c)

c) ABO blood group

d)

d) Polydactyly

19.

Cytoplasmic inheritance is also known as:

a)

a) Nuclear inheritance

b)

b) Maternal inheritance

c)

c) Paternal inheritance

d)

d) Epigenetic inheritance

20.

Linkage was first discovered in:



a)

a) Pea plants

b)

b) Drosophila melanogaster

c)

c) Maize

d)

d) Yeast

21.

Which chromosome structure is found in amphibian oocytes and used for active transcription studies?


a)

a) Polytene chromosome

b)

b) Lampbrush chromosome

c)

c) Metacentric chromosome

d)

d) Telocentric chromosome

22.

Somatic cell hybridization is useful for:

a)

a) Gene therapy

b)

b) Assigning genes to chromosomes

c)

c) Producing hybrids between species

d)

d) Both (b) and (c)

23.

Who is regarded as the "Father of Linkage and Crossing Over"?



(a)  

24.

Erythroblastosis fetalis (Hemolytic disease of newborn) occurs when:


a)

a) Mother is Rh⁺ and fetus is Rh⁻

b)

b) Mother is Rh⁻ and fetus is Rh⁺

c)

c) Both are Rh⁺

d)

d) Both are Rh⁻

25.

The Rh factor in humans is due to:

a)

a) Genes located on X chromosome

b)

b) Genes located on chromosome 1

c)

c) Genes located on chromosome 9

d)

d) Genes located on chromosome 14

26.

2.Codominance is characterized by

a)

a.intermediate expression

b)

b.blending of traits

c)

c.simultaneous expression

d)

both b and c

27.

4.The multiple phenotypic expression of a single gene is referred to as (a)   .

28.

8.State true or false: Variations in phenotype among individuals of a species may be due to genetical or environmental differences but not both.

a)

True

b)

False

29.

14.The gene that is being suppressed during inter genic interaction is known as (a)   gene.

30.

15.Presence of recessive alleles at both gene loci and presence of dominant allele at the hypostatic locus produce the same phenotype. What type of interaction is seen in this case?

a)

Incomplete dominance

b)

Dominant epistasis

c)

Codominance

d)

Recessive epistasis

31.

In summer squash if you cross different varieties of true breeding sphere shaped squash, you get a disk shaped progeny. What phenomenon is seen here?

a)

Gene interaction

b)

Epistasis

c)

Multiple allele

d)

Codominance

32.

Two pairs of non-allelic dominant genes which interact to produce one phenotype is

a)

Complementary genes

b)

  Supplementary genes

c)

Epistasis

d)

Dihybrid cross

33.

The gene that masks or suppresses other gene is called

a)

Epistasis

b)

Hypostatic

c)

Epistatic

d)

Complementary genes

34.

What does autosomal mean?

a)

Relating to a gene on a sex chromosome

b)

A chromosome disorder

c)

Relating to a gene on a chromosome that is not a sex chromosome

d)

Chromosomes with the same genes

35.

What does pleiotropy mean?

a)

One gene controlling multiple traits

b)

One gene controlling one trait

c)

One gene that does not control any trait

d)

Multiple genes that control one trait

36.

What does sex-linked refer to?

a)

A gene that exists on a chromosome

b)

A gene that does not differ in inheritance patterns between sexes

c)

A gene that is on an autosomal chromosome

d)

A gene that is on a sex chromosome

37.

What does codominance mean?

a)

Do not pick this one :(

b)

Where the phenotype of the heterozygote is an intermediate of the two homozygote phenotypes

c)

Where the heterozygote shows both the phonotypes of the homozygotes simultaneously

d)

Where the heterozygote has the same phenotype as one of the homozygotes

38.

What does epistasis mean?

a)

More than one gene controlling more than one trait

b)

One gene controlling more than one trait

c)

More than one gene controlling one trait

d)

One gene controlling one trait

39.

If a gene controlling flower color showed incomplete dominance what would the offspring of the cross between a red flower and white flower look.

a)

Pink

b)

Red

c)

White

d)

Red and white

40.

If a gene controlling flower color was completely dominant what would the offspring of the cross between a red flower and white flower look. Red is dominant to white.

a)

Red and white

b)

Red

c)

white

d)

Pink

41.

If a gene controlling flower color showed codominance what would the offspring of the cross between a red flower and white flower look.

a)

White

b)

Red

c)

Red and white

d)

Pink

42.

Persons having genotype IAIB would show the blood group AB. This is because of

a)

Pleiotropy

b)

Co-dominanace

c)

Segregation

d)

Incomplete dominanace

43.

All genes located on the same chromosome

a)

forms different groups depending upon their relative distance

b)

form one linkage group

c)

will not form any linkage groups

d)

forms interactive group that affect the phenotype

44.

In a dihybrid cross if you get 9:3:3:1 ratio, it denotes that

a)

The alleles of two genes are interacting with each other

b)

Its multigenic inheritance

c)

It exhibits multiple allelism

d)

The alleles of two genes are segregating independently

45.

Ocassionally a single gene may express more than one effect. This phenomenon is called

a)

multiple allelism

b)

mosaicism

c)

pleiotropy

d)

polygeny

46.

In a marriage between male with blood group A and female with blood group B, the progeny had either blood group AB or B. What could be the possible genotype of parents?

a)

IA i (Male) ; IB i (Female)

b)

IA i (Male) ; IB IB(Female)

c)

IAIA(Male) ; IBIB (Female)

d)

IA IA (Male) ; IB i (Female)

47.

_________ is called null allele

a)

IA

b)

IB

c)

IO

d)

none of these

48.

ABO blood group in man is controlled by

a)

multiple allele

b)

lethal gene

c)

sex linked genes

d)

Y linked genes

49.

If the child's blood group is O, father's blood group is A and mother's blood group is B. then the genotype of the parents will be

a)

IA IA and IB IO

b)

IA Io and IB IO

c)

IA IO and IO IO

d)

IO IO and IB IB

50.

Inheritance of ABO blood group system is an example of

a)

(a) dominance

b)

(b) epistasis

c)

(c) partial dominance

d)

(d) multiple allelism

51.

A person with antigens A and B and no antibodies belongs to blood group or in which blood group antibodies are absent

a)

(a) O

b)

(b) AB

c)

(c) B

d)

(d) A

52.

This is the genotype of blood group A

a)

(a) IA IA

b)

(b) IA IO

c)

(c) IB IB

d)

(d) IA IA or IA IO

53.

ABO blood groups in humans are controlled by the gene I. It has three alleles – IA, IB and I. Since there are three different alleles, six different genotypes are possible. How many phenotypes can occur?

a)

a) Three

b)

b) One

c)

c) Four

d)

d) Two

54.

1. The term used to describe the number of chromosomes in an egg or sperm cell is

a)

A. diploid

b)

B. gamete

c)

C. haploid

d)

D. zygote

55.

8. The diagram shows the chromosomes from one person.


What can be deduced about the person who has these chromosomes?

a)

A. a female with Down’s syndrome

b)

B. a male with Down’s syndrome

c)

C. a normal female

d)

D. a normal male

56.

11. Gametes are produced by the process of ------------

a)

A. mitosis

b)

B. meiosis

c)

C. crossing-over

d)

D. replication

57.

12. Chromosomes that determine the body characteristics -------------------------------

a)

A. Allosomes

b)

B. Autosomes

c)

C. Karyotype

d)

D. Sex linkage

58.

Which of the following is an example of a sex-linked recessive disorder found on the X chromosome?

a)

Huntington's disease

b)

Duchenne muscular dystrophy

c)

Cystic fibrosis

d)

Red-Green Color blindness

59.

What genotype should be placed in the box with a question mark?

a)

XHXh

b)

XHXH

c)

XhY

d)

XHY

60.

What percentage of the offspring could be colorblind?

a)
25%
b)
75%
c)
10%
d)

0%

61.

What gender of the offspring will be colorblind?

a)

male

b)

female

62.

What percentage of the offspring could have normal vision?

a)
50%
b)
75%
c)
25%
d)
100%
63.
Hemophilia is a recessive x-linked disorder.
Which genotype represents a female who is a carrier for hemophilia?
a)
XHXh
b)
XhXh
c)
XHXH
d)
XhY
64.

The study of the inherited changes in gene expression that occur without a change in gene sequence and influence how an organism's genes express themselves. Mechanisms are influenced by food and environment. They play an important role in the fetal basis of adult disease susceptibility.

a)

bionomics

b)

genomics

c)

genetics

d)

epigenetics

65.

Protein molecules around which DNA is tightly coiled in chromatin

a)

histones

b)

casein

c)

nucleosome

d)

chromosome

66.

A chemical modification of DNA that does not affect the nucleotide sequence of a gene but makes that gene less likely to be expressed.

a)

activators

b)

methylation

c)

acetylation

d)

proteins

67.

How can a person's muscle cells have the same exact DNA sequences as their nerve cells even though the look and perform completely different?

a)

The two different cells become mutated

b)

They actually have different DNA in the two types of cells.

c)

The proteins expressed in each cell are different

d)

The genome of the different cells changes

68.

What is a Gene?

a)

A segment of DNA that encodes for a protein

b)

A segment of RNA that encodes for a protein

c)

Chromosome

d)

chromatin

69.

Epigenetics refers to changes in:

a)

DNA sequence

b)

Gene structure

c)

Gene expression

d)

DNA frequency

70.

In terms of epigenetics, acetylated histones usually result in which of the following?

a)

Increase in transcription/ gene expression

b)

Decrease in transcription/ gene expression

c)

Increase in DNA - lamina association

d)

Decrease in DNA - lamina association 

71.

Euchromatin ...

a)

genetically active

b)

Genetically inactive

c)

condensed

d)

present in both prokaryotes and eukaryotes

72.

Heterochromatin ...

a)

genetically active

b)

present only in eukaryotes

c)

present in both prokaryotes and eukaryotes

d)

consists of less amount of DNA

73.

A group of genes that are regulated together is called a(n)

a)

operator

b)

promoter

c)

operon

d)

repressor

74.

The study of changes in organisms caused by modification of gene expression rather than alteration of the genetic code itself

a)

hypogenomics

b)

epigenetics

c)

microgenomics

d)

none of these

75.

Epigenetics refers to changes in:

a)

DNA sequence

b)

Gene structure

c)

Gene expression

d)

DNA frequency