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WorksheetsTissue Regeneration and Neoplasia Quiz
Total questions: 52
Worksheet time: 26mins
Healing is defined as…
Formation of clot in wound
Replacement of destroyed tissue by living tissue
Invasion of microbes into wound
Removal of dead tissue by macrophages
Regeneration means…
Replacement of lost tissue by scar
Replacement of destroyed tissue by the same type of cells
Replacement of necrotic cells by fat
Healing with infection
Fibrosis (repair by scar) means…
Replacement of damaged cells by identical tissue
Replacement of tissue by supportive fibrous tissue
Healing without scar
Replacement of tissue by fat cells
In the central nervous system, repair occurs by…
Regeneration of neurons
Gliosis (fibrosis by glial tissue)
Fat deposition
Hemorrhage
Labile cells are characterized by…
Non-dividing nature
Continuous division under normal conditions
No regeneration
Permanent inability to proliferate
Which of the following is an example of labile cells?
Hepatocytes
Skeletal muscle cells
Surface epithelium
Neurons
Stable cells are characterized by…
Continuous division throughout life
Non-dividing and no regeneration
Divide only in response to injury
Derived only from neurons
Hepatocytes are classified as…
Labile cells
Stable cells
Permanent cells
None
Which of the following are permanent cells?
Fibroblasts
Nerve cells
Endothelial cells
Renal tubular cells
Muscle cells belong to which category?
Labile
Stable
Permanent
None
Healing by first intention is seen in…
Clean surgical wound with sutures
Large contaminated wound
Ulcer healing
Burn wound
Healing by second intention is seen in…
Small incised wound
Large infected wound with tissue loss
Sutured skin incision
Superficial scratch
Which healing type has minimal granulation tissue?
Primary intention
Secondary intention
Both
None
Which healing type has prominent wound contraction?
Primary intention
Secondary intention
Both
None
The scar in healing by first intention is usually…
Large and irregular
Thin and linear
Absent
Keloid-like
The scar in healing by second intention is usually…
Small and thin
Wide and irregular
Absent
Atrophic
Healing time in first intention is…
Long
Short
Absent
Variable only with infection
Healing time in second intention is…
Short
Long
Same as first intention
Absent
Which is a local factor affecting wound healing?
Age
Anemia
Diabetes mellitus
Blood supply
Which systemic factor delays wound healing?
Good nutrition
Glucocorticoid therapy
Adequate blood flow
Youth
Squamous cell carcinoma developing in a chronic scar is called…
Kaposi’s sarcoma
Marjolin’s ulcer
Keloid ulcer
Epidermal carcinoma
Implantation of epithelium into the dermis during wound healing may lead to…
Epidermal cyst
Keloid
Ulcer
Fibroma
Healing time in secondary intention is…
Short
Long
Absent
Same as primary
Which systemic disease delays healing due to high blood sugar?
Uremia
Diabetes mellitus
Malignancy
Anemia
Stable cells under normal conditions…
Continuously divide
Do not divide at all
Divide rapidly only after injury
Replace lost tissue by scar
Permanent cells after injury are replaced by…
Regenerated identical cells
Fibrous scar tissue
Bone tissue
Labile cells
Healing by second intention differs from first intention by…
Absence of granulation tissue
Faster healing
Larger scar and wound contraction
Minimal scar
Which of the following is defined as a complete failure of development of an organ or tissue?
Aplasia
Agenesis
Hypoplasia
Hamartoma
A rudimentary organ is seen in…
Agenesis
Aplasia
Hypoplasia
Teratoma
Failure of an organ to reach normal size, resulting in undersized organ with limited function is called…
Agenesis
Hypoplasia
Atrophy
Dysplasia
Which of the following is a tumor-like lesion characterized by presence of normal tissue in an abnormal site?
Hamartoma
Choristoma
Teratoma
Embryonal tumor
An overgrowth of mature cells and tissues normally present in the affected part but irregularly arranged is called…
Hamartoma
Teratoma
Hypoplasia
Anaplasia
Which congenital abnormality of growth arises from totipotent germ cells and contains more than one germ layer?
Dysplasia
Teratoma
Embryonal tumor
Hamartoma
Highly malignant tumors derived from embryonic cell remnants that occur mostly in infants and young children are…
Embryonal tumors
Teratomas
Hamartomas
Adenomas
Retinoblastoma is an example of…
Pluripotent embryonic tumor
Unipotent embryonic tumor
Hamartoma
Teratoma
Nephroblastoma and hepatoblastoma are examples of…
Hamartoma
Pluripotent embryonic tumor
Teratoma
Aplasia
Dysplasia is characterized by all EXCEPT…
Loss of polarity
Pleomorphism
Intact basement membrane
Invasion into surrounding tissue
Increased nucleo-cytoplasmic ratio and hyperchromatic nuclei are features of…
Normal tissue
Dysplasia
Hamartoma
Agenesis
Mild dysplasia involves…
One third of epithelium
Two thirds of epithelium
Full thickness of epithelium
None of the above
Moderate dysplasia involves…
Lower one third of epithelium
Lower two thirds of epithelium
All thickness of epithelium
Basement membrane destruction
Severe dysplasia (carcinoma in situ) involves…
Lower one third of epithelium
Lower two thirds of epithelium
All thickness of epithelium
Only superficial layer
The fate of dysplasia may include…
Regression
Persistence
Progression
All of the above
Neoplasia is defined as…
Controlled multiplication of cells
Autonomous and purposeless growth of cells
Regression of tissue
Developmental malformation
Which is NOT true about neoplasia?
Autonomous
Progressive
Controlled by physiological stimuli
May be benign or malignant
Anaplasia refers to…
Complete loss of differentiation
Partial differentiation with intact BM
Increase in cell size
Regression of growth
Hyperplasia is characterized by…
Arises spontaneously independent of stimuli
Regresses when stimulus is removed
Purposeless growth
Uncontrolled proliferation
Neoplasia differs from hyperplasia because it…
Is controlled by stimuli
Regresses when stimulus is removed
Progresses irrespective of stimuli
Always increases normal function
Benign tumors grow by…
Infiltration and metastasis
Expansion compressing surrounding tissues
Direct hematogenous spread
Lymphatic permeation
A common gross feature of benign tumors is…
Encapsulation
Frequent hemorrhage
Ill-defined irregular edges
Ulceration
Malignant tumors are usually…
Small, encapsulated, and slow-growing
Large, non-encapsulated, and fast-growing
Always cystic and benign
Harmless to the host
Malignant tumors often recur after surgical removal because…
They remain local at the site of origin
They send metastases to distant sites
They are encapsulated
They regress spontaneously
Which statement is true about locally malignant tumors?
They grow rapidly and metastasize widely
They spread locally without distant metastasis
They are always benign
They never infiltrate surrounding tissues
