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WorksheetsPODA III EXAM 3- Fall 2025
Total questions: 39
Worksheet time: 22mins
WOTF is a DNA-containing Virus?
EEE (Eastern Equine Encephalitis) Virus
Rotavirus
Rabies Virus
Vaccinia
Measles
What causes the Multifocal Leukoencephalitis/Encephalopathy?
Echovirus
Variola virus
John Cunningham Virus
Machupo virus
CMV (cytomegalovirus)
WOTF is NOT a component of the QUAD pill (Stribild)?
Elvitegravir
Cobicistat
A nucleotide
Tenofovir Alafenamide
Emtricitabine
Ara-C (Cytarabine) is beneficial in the management of WOTF?
Acute Granulocytic Leukemia
Shingles
Burkitts Lymphoma
Acute and Chronic Myelogenous Leukemia (AML/CML)
Chickenpox
Amantadine (Gocovri) is beneficial in the treatment of WOTF?
EPS (extrapyramidal syndrome)
HIV/AIDS (no longer clinically relevant)
Parkinsons Disease
Dyskinesia
Restless Leg Syndrome
WOTF works by binding to GP 120, therefore preventing the connection of virus?
Selzentry
Ibalizumab
Peramivir
Pleconaril
Temsavirbrand: (Fostemsavir)
WOTF works by inhibiting DNA terminase?
Denavir
Entecavir
Adefovir
Eteplirsen
Letermovir
WOTF inhibits the DNA repair enzyme Enzyme apex nuclease 1?
Brivudine - main indication: shingles
Amantadine
Zidovudine
Trifluridine
WOTF is a purine analog that is employed in the treatment of CMV-induced retinitis?
Acyclovir
Ganciclovir - IV, PO, eye insert, eye drops
Vibrudine
Sidofovir
PFA (phophonoforfic acid)
WOTF is LEAST LIKELY to be observed as an adverse effect of Tenofovir (Viread)?
Fanconi syndrome
Increase in bone density
Renal insufficiency
Non-specific GI adverse effects (N/V/D)
Osteomalacia
WOTF produces its pharmacological effect by inhibiting the protein kinase activity of CMV enzyme called pUL97?
Maribavir- Livintencity
WOTF is an antisense oligonucleotide that you can use to treat hepatitis B?
Fomivirsen
Bepiroversen
Afovirsen
Mipomersen
Eteplirsen
WOTF is not a common characteristic of the Protease Inhibitors that you use for aids
Fecal excretion
Hypoglycemia
Inhibition of cleavage of the HIV encoded gag pol polyprotein
Metabolism by CYP3A4
Oral administration
WOTF is an adverse effect of AZT? SATA
Lypodystrophy
Myositis
Enlargement of the liver
Lactic acidosis
Muscle weakness/fatigue
WOTF is an AE of Azidothymidine? SATA (all NRTI can cause this)
hyperpigmentation of skin and nails
hyperlipidemia and hyperglycemia
granulocytopenia
microcytic anemia
wernicke's syndrome
WOTF is an adverse effect of Atazanavir( Reyataz)?
A decrease in bilirubin levels (NO B/C hyperbilirubinemia is an ADA)
Kidney stones "nephrolithiasis"
Gallstones "cholelithiasis"
Yellowing of the sclera/ "scleral icterus"
Prolongation of the PR interval
What is the dosage of Acyclovir when it is being used to treat shingles?
200 mg PO QD
800 mg PO QD
400 mg IV QD
800 mg 5 times a day
WOTF is true about Efavirenz?
It has an autoinduction property
It is administered QHS
It has a half-life of 40-55 hrs
It is a substrate for 3A4
It can be administered IV
WOTF would be an adverse effect of Efavirenz?
Insomnia
Somnolence
Bad dreams
GI adverse effects
Fatigue
WOTF is a vector of St. Louis Encephalitis Virus?
Aedes Egipty
Culex Tarsalis
Culex Univittatus
Culiseta Melanura
Aedes Abopictus
WOTF is an A/E of Foscarnet?
Hallucination and Seizures
Irritability and Parasthesia
first degree of AV Block
Circumoral paresthesis
Numbness and Hallucination
Raltegravir (Isentress) can produce all of the following as adverse effects
Myopathy
TEN- Toxic epidermal necrolysis
SJS- steven johnson syndrome
Decreased CPK
Suicidal Ideation
WOTF is MOST LIKELY to increase the hepatotoxicity of Raltegravir/ Isentress?
Methotrexate/Trexall
Tylenol
Maraviroc/ Selzentry
INH (Isoniazid)
Nizoral (ketaconazole)
WOTF is best classified as an NNRTI?
Etravirine
Nevirapine
Lamivudine - NRTI
Rilpivirine
Tiplenavir
WOTF is a component of Symtuza?
Cobicistat
Emtricitabine (M-10)
Darunavir
Tenofovir Alafenamide Fumarate
Tenofovir Disoproxil
WOTF will enhance/increase the hematologic toxicity of AZT when administered concurrently with AZT?
Endomethacin
Acetaminophen
Acyclovir
Probenecid
Aspirin
A patient who is receiving Mavyret for their treatment of Hepatitis C is actually receiving WOTF?
Glecaprevir
Tenofovir Disoproxil Fumarate
Paritaprevir
Sofosbuvir
Pibrentasvir
WOTF products contain Dolutegravir?
Juluca
Epzicom
Cabenuva
Dovato
Triumeq
WOTF is an inhibitor of NS5B polymerase inhibitor for Hep C virus? (Look for ~buvir)
Ombitasvir
Dasabuvir
Voceprevir
Voxilaprevir
Sofosbuvir
WOTF statement is true about lenacapravir/ (Sunlenca)?
It is metabolized by 3A4 and UGT 1A1
It is primarily excreted through the renal system
It is administered orally and intravenously
Has a high PPB capability
It is administered concurrently with islatravir (for optimum effectiveness)
WOTF is least likely to be classified as a pyrimidine nucleoSIDE antiviral agent?
Ara- A
Idoxuridine
Trifluridine (Vipotic®)
Fiac
Ara-C (Arabinoside Cytosine)
All of the following are inhibitors of HIV protease except one?
Saquinavir
Ritonavir
Telaprevir
Darunavir
Atazanavir
WOTF will exacerbate a skin reaction, like TENS, that is a manifestation of the AE of Raltegravir (Isentress ®)?
Isoniazid (INH)
Tylenol
Atorvastatin
Methotrexate (MTX)
Darunavir
To which of the following virus groups does the causative agents of Bolivian hemorrhagic fever belong?
picornavirus
rhabdovirus
orthomyxovirus
arenavirus
papovavirus
WOTF is used to treat Hepatitis C?
Nusinersen
Hepcinat
ara-A
Baraclude
Hepsera
WOTF is an appriopriate dose of Acyclovir for the treatment of 'chickenpox'?
800 mg po qd
400 mg po qd
200 mg IV qd
200 mg IV TID
400 mg po QID
WOTF statements about Atazanavir (Reyataz) is False?
It inhibits CYP 3A4
It undergoes renal excretion primarily
It is a substrate for CYP 3A4
it is administered orally with food
it should not be administered concurrently with omeprazole
WOTF is BEST classified as a Non-Nucleoside Reverse Transcriptase Inhibitor?
Epivir
Intelence
Dolutegravir
Pifeltro
Aptivus
Which of the following is BET classified as a Chemokine receptor inhibitor?
a. Enfuvirtide
b. Zanamivir
c. Mogamulizumab (Poteligeo)
d. Taribavirin
e. Vidarabine
