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WorksheetsRESP 150 Exam 3 Chapters 13-17 Review Quiz
Total questions: 103
Worksheet time: 58mins
Pentamidine is:
a bactericidal agent
an antiprotozoal agent
an antiviral agent
an antibiotic
Inhaled pentamidine is indicated for:
treatment of bronchospasm.
bacterial pneumonia in cystic fibrosis patients.
prevention of Pneumocystis jiroveci pneumonia (PJP).
treatment of respiratory syncytial virus (RSV).
Local airway side effects of aerosolized pentamidine include which of the following?
Wheezing
Coughing
Shortness of breath
Sweating
Ribavirin is active against which of the following?
Tuberculosis organisms
Influenza virus
Respiratory syncytial virus (RSV)
Pneumocystis jiroveci organisms
The normal dosage schedule of ribavirin is:
20 mg/ml nebulized for 12 to 18 hr per day for 3 to 7 days.
20 mg/ml nebulized for 24 hr per day for 5 days.
40 mg/ml nebulized for 3 to 6 hr per day for 3 to 7 days.
30 mg/ml nebulized for 12 to 18 hr per day for 14 days.
On what principle does the small particle aerosol generator (SPAG) unit operate?
Venturi
Hydrodynamic
Jet shearing
Ultrasonic
Respiratory syncytial virus (RSV) can cause which of the following?
Asthma
Bronchiolitis
Pneumothorax
Pneumonia
A physician asked you to suggest an aerosolized antiinfective for a cystic fibrosis patient with chronic Pseudomonas aeruginosa infection. Which is the most appropriate medication?
Levalbuterol
Pentamidine
Ribavirin
Tobramycin
Tobramycin is a member of which antibiotic group?
Aminoglycosides
Antifungals
Fluoroquinolones
First-generation cephalosporins
After reviewing your patient’s chart, you notice he experiences wheezing during his NebuPent treatments. What should you suggest to his physician?
Stop this medication immediately because it is causing respiratory side effects.
Keep giving the medication as prescribed; wheezing does not cause any problems.
Have the patient use a β-adrenergic bronchodilator before inhaling aerosolized NebuPent.
Explain to the other therapists they should not chart adverse side effects.
The most common pathogens responsible for community-acquired pneumonia include which of the following?
Haemophilus influenzae
Chlamydrophila pneumoniae
Streptococcus pneumoniae
Staphylococcus aureus
Penicillins are:
bactericidal.
bacteriostatic.
virucidal.
fungicidal.
The most common adverse reaction to penicillin is:
headache.
nausea.
allergic reaction.
seizures.
The treatment of choice for pulmonary infections such as aspergillosis, histoplasmosis, and coccidioidomycosis is:
rifampin.
ciprofloxacin.
ampicillin.
amphotericin B.
A patient with human immunodeficiency virus (HIV) has been diagnosed with Pneumocystis jiroveci. You are asked to recommend an antibiotic that is active against Pneumocystis jiroveci. Your recommendation would be:
pentamidine.
TMP-SMX.
levofloxacin.
tetracycline.
An important mediator of local inflammatory responses is:
histamine.
epinephrine.
acetylcholine.
Tylenol.
A wheal and flare reaction is characterized by which of the following?
Welt formation
Local redness
Fever
Local swelling
Receptors located on nerve endings, smooth muscle, and glandular cells that are involved in inflammation and allergic reactions are:
adrenergic receptors.
cholinergic receptors.
H1 receptors.
H2 receptors.
Cough suppressants act by:
numbing the upper airway.
depressing the cough center in the medulla.
reducing bronchospasm.
decreasing mucus production.
Which of the following may be prescribed as an antitussive?
Pseudoephedrine (Sudafed)
Diphenhydramine hydrochloride (Benadryl)
Guaifenesin (Robitussin)
Benzonatate (Tessalon)
What is the primary function of alpha-1 antitrypsin (A1AT) in the body?
Stimulate red blood cell production
Inhibit neutrophil elastase to protect tissues
Promote liver enzyme activity
Transport oxygen in the blood
Which organs are primarily affected by A1AT deficiency?
Heart and kidneys
Brain and pancreas
Lungs and liver
Skin and intestines
What is the genetic inheritance pattern of A1AT deficiency?
X-linked recessive
Autosomal dominant
Autosomal recessive
Mitochondrial inheritance
How does A1AT deficiency lead to emphysema?
By increasing mucus production in the lungs
By allowing neutrophil elastase to break down alveolar walls
By causing bronchial constriction
By reducing surfactant production
Which liver condition is commonly associated with A1AT deficiency?
Cirrhosis due to alcohol
Hepatitis C
Neonatal hepatitis and liver fibrosis
Hemochromatosis
What is the most common defective allele associated with severe A1AT deficiency?
M allele
Z allele
S allele
A allele
Which diagnostic test is used to confirm A1AT deficiency?
Chest X-ray
Liver biopsy
Serum A1AT level and phenotype/genotype testing
Pulmonary function test
What treatment options are available for patients with A1AT deficiency?
Antibiotics and antihistamines
A1AT replacement therapy and lifestyle modifications
Chemotherapy and radiation
Antiviral medications
Why might liver transplantation be considered in some A1AT deficiency cases?
To treat lung infections
To correct genetic mutations
To address severe liver damage or failure
To improve oxygen delivery
What lifestyle change is especially important for individuals with A1AT deficiency to prevent lung damage?
Avoiding dairy products
Quitting smoking
Increasing protein intake
Reducing salt consumption
What is the primary role of alpha-1 antitrypsin (AAT) in the lungs?
Stimulate mucus production
Transport oxygen to alveoli
Inhibit neutrophil elastase to protect lung tissue
Promote surfactant secretion
How does AAT deficiency lead to emphysema?
It causes bronchial constriction
It allows neutrophil elastase to destroy alveolar walls
It increases mucus viscosity
It reduces oxygen diffusion
Which type of emphysema is most commonly associated with alpha-1 antitrypsin (AAT) deficiency?
Centriacinar
Panacinar
Bullous
Interstitial
Which genotypes are associated with severe AAT deficiency?
MM
MS
ZZ
SS
What symptoms might indicate liver involvement in AAT deficiency?
Hematuria and flank pain
Jaundice and hepatomegaly
Bradycardia and hypotension
Cyanosis and clubbing
Which test is used to confirm a diagnosis of AAT deficiency?
Chest X-ray
Liver biopsy
Serum AAT level and genetic testing
Pulmonary function test
What is the purpose of augmentation therapy in AAT deficiency?
Cure the genetic mutation
Restore protective levels of AAT in the lungs
Reduce liver inflammation
Increase surfactant production
Why is smoking especially harmful in patients with AAT deficiency?
It increases mucus clearance
It accelerates elastin breakdown and lung damage
It boosts AAT production
It reduces liver enzyme activity
What is the difference between panacinar and centriacinar emphysema?
Panacinar affects upper lobes; centriacinar affects lower lobes
Panacinar involves uniform alveolar destruction; centriacinar is patchy
Panacinar is caused by smoking; centriacinar by genetics
Panacinar is reversible; centriacinar is not
Which population should be screened more aggressively for AAT deficiency?
Children with asthma
Adults with early-onset COPD or unexplained liver disease
Smokers over age 65
Patients with frequent sinus infections
The recommended dosage of Prolastin-C is:
30 mg/kg once daily.
40 mg/kg once weekly.
50 mg/kg once weekly.
60 mg/kg once weekly.
Potential adverse effects of Prolastin-C administration include which of the following?
Fever
Exacerbation
Arrhythmias
Flu-like symptoms
Physical symptoms of nicotine withdrawal include which of the following?
Irritability
Weight gain
Craving for nicotine
Anxiety
Sleep disturbances
The nicotine replacement method that provides the most consistent level of nicotine and that is easy and convenient is:
the transdermal patch
gum
a nasal spray
an inhaler
The drug used to treat hypoxic respiratory failure in newborns with pulmonary hypertension is:
ribavirin.
Xopenex.
Survanta.
nitric oxide.
Which of the following affect penetration and deposition of an aerosol in neonatal and pediatric patients?
Inertial impaction
Particle size
Velocity
Sedimentation
A dry powder inhaler (DPI) is not recommended for children younger than age:
5 yr
7 yr
8 yr
12 yr
A respiratory therapist is administering a nebulizer treatment to an intubated pediatric patient and notices an increase in the patient’s airway pressure. What could be the cause?
The nebulizer.
The medication is working.
PEEP has decreased.
Decrease in volume delivered by the ventilator.
A patient is considered a child if he or she is:
less than 37 wk of gestational age
in the first month of postnatal life
12 to 18 yr
1 to 12 yr
Patients with a history of __________ should not use Afrezza.
hypertension
lung disorders
diabetes mellitus
gout
Match the brand name to the generic name.
Pentamidine isethionate
NebuPent
Ribavirin
Virazole
Tobramycin
TOBI
Aztreonam
Cayston
Zanamivir
Relenza
Match the brand name to the generic name.
Oseltamivir
Tamiflu
Amphotericin B
Fungizone
Fluconazole
Diflucan
Oxymetazoline
Afrin
Phenylephrine
Sudafed PE
Match the brand name to the generic name.
Pseudoephedrine Hydrochloride
Sudafed
Chlorpheniramine
Chlor-Trimeton
Diphenhydramine HCL
Benadryl
Cetirizine
Zyrtec
Loratadine
Claritin
Match the brand name to the generic name.
Fexofenadine
Allegra
Guaifenesin
Mucinex
Benzonatate
Tessalon
Dextromethorphan
Robitussin
Varenicline
Chantix
Match the brand name to the generic name
Clinidine
Catapres
Bupropion
Zyban
Nortriptyline
Pamelor
Match the brand name to the generic name.
Iloprost
Ventavis
Treprostinil
Tyvaso
Inhaled Insulin
Afrezza
What is the trade name for Pentamidine?
Virazole
NebuPent
TOBI
Pulmozyme
How is Pentamidine administered?
Oral tablet
IV infusion
Inhalation via Respirgard II
Nasal spray
What is a side effect of Pentamidine?
Rash
Metallic taste
Hypertension
Bradycardia
What is the trade name for Ribavirin?
Relenza
Virazole
Prolastin
Mucomyst
What device is used to deliver Ribavirin?
DPI
SPAG
MDI
Nebulizer
What type of drug is Ribavirin?
Antibiotic
Antifungal
Antiviral
Bronchodilator
What is the drug class of Relenza?
Beta agonist
Neuraminidase inhibitor
Corticosteroid
Antihistamine
What does Relenza treat?
RSV
Tuberculosis
Influenza A and B
COPD
What is Isoniazid used for?
RSV
Influenza
Tuberculosis
Asthma
How are bacteria identified?
CT scan
Gram stain and culture
MRI
Ultrasound
What does bacteriostatic mean?
Kills bacteria
Inhibits bacterial growth
Enhances bacterial replication
Neutralizes toxins
What do MRSA and VRE have in common?
Viral origin
Antibiotic resistance
Fungal infection
Airborne transmission
How does penicillin work?
Inhibits protein synthesis
Disrupts DNA replication
Inhibits cell wall synthesis
Blocks folic acid
Cephalosporins are classified by:
Route of administration
Spectrum of activity
Cost
Manufacturer
What drug treats Pseudomonas aeruginosa in CF?
Ribavirin
TOBI
Relenza
Mucomyst
A side effect of Amphotericin B is:
Nephrotoxicity
Hypertension
Hyperglycemia
Bradycardia
What does sympathomimetic mean?
Blocks sympathetic activity
Mimics parasympathetic system
Mimics sympathetic system
Inhibits neurotransmitters
Repeated use of adrenergic nose spray may cause:
Bronchospasm
Rebound congestion
Diarrhea
Fever
Acetylcysteine works by:
Cleaving DNA
Hydrating mucus
Breaking disulfide bonds
Stimulating cilia
Dornase alfa is used for:
Asthma
CF
COPD
Tuberculosis
Hypertonic saline helps by:
Suppressing cough
Hydrating airway surface
Blocking receptors
Reducing inflammation
A common expectorant is:
Codeine
Guaifenesin
Dextromethorphan
Albuterol
What treats a dry hacking cough?
Expectorant
Antitussive
Mucolytic
Antibiotic
Risk of OTC cold meds includes:
Enhanced immunity
Masking serious conditions
Improved sleep
Weight loss
Side effects of OTC cold meds may include:
Hypoglycemia
Drowsiness
Rash
Constipation
Drugs for α1-antitrypsin deficiency include:
TOBI
Prolastin
Ribavirin
Dornase alfa
Mechanism of α1-antitrypsin therapy:
Stimulates mucus clearance
Inhibits neutrophil elastase
Blocks viral replication
Diagnosis of α1-antitrypsin deficiency includes:
Chest X-ray
Serum AAT level and genetic testing
Sputum culture
Skin test
Smoking cessation drugs include:
Dornase alfa
Varenicline
Ribavirin
Amphotericin B
Signs of nicotine addiction:
Rash
Cravings and irritability
Fever
Cough
When to recommend nicotine replacement?
When patient has asthma
When patient expresses desire to quit
When patient has pneumonia
When patient is hospitalized
Nitric oxide is a:
Bronchodilator
Pulmonary vasodilator
Antibiotic
Antiviral
Toxic effect of nitric oxide:
Methemoglobinemia
Rash
Bradycardia
Drug used in diabetic patients:
Dornase alfa
Afrezza
Ribavirin
TOBI
Aerosol delivery in infants is affected by:
Age only
Mask fit and breathing pattern
Drug type
Temperature
Age range of premature neonate:
<37 weeks gestation
Birth to 1 month
1-12 months
12-18 years
Age range of neonate:
<37 weeks gestation
Birth to 1 month
1-12 months
12-18 years
Age range of infant:
<37 weeks gestation
Birth to 1 month
1–12 months
12–18 years
Age range of adolescent:
<37 weeks gestation
Birth to 1 month
1–12 months
12–18 years
Which is a nicotine replacement therapy?
Dornase alfa
Nicotine patch
Ribavirin
TOBI
What is Zyban?
Antibiotic
Antiviral
Bupropion
Corticosteroid
What is Chantix?
Varenicline
Codeine
Guaifenesin
Ribavirin
What improves success in smoking cessation?
Single therapy
Combination therapy
Avoidance
Cold turkey
What is the route for Prolastin?
Oral
IV
Inhalation
Subcutaneous
What is the route for Afrezza?
Oral
IV
Inhalation
Subcutaneous
What is the route for Dornase alfa?
Oral
IV
Inhalation
Subcutaneous
What is the route for Ribavirin?
Oral
Intravenous
Inhalation via SPAG unit
Subcutaneous
