wayground logo

Free Printable Worksheets

Font size

S
M
L
XL
Worksheets

Cell Structure, Organelles, and Membrane Transport

Total questions: 150

Worksheet time: 1hrs 15mins

Name
Class
Date
1.

Which feature best distinguishes prokaryotic cells from eukaryotic cells?

a)

Presence of ribosomes

b)

True nucleus enclosed by a membrane

c)

Ability to perform cellular respiration

d)

Presence of a cell membrane

2.

In prokaryotic cells, where is circular DNA located?

a)

Nucleolus

b)

Nucleoid

c)

Golgi apparatus

d)

Mitochondrion

3.

Which organelle is correctly matched with its primary function?

a)

Golgi apparatus — protein synthesis

b)

Rough ER — lipid detoxification

c)

Mitochondria — ATP production via cellular respiration

d)

Lysosomes — photosynthesis

4.

Ribosomes are found in which locations in a eukaryotic cell?

a)

Only in the nucleolus

b)

Free in cytoplasm and bound to the Rough ER

c)

Only on the Smooth ER

d)

Embedded in the cell wall

5.

Which set lists structures specific to plant cells as described?

a)

Lysosomes, centrosomes, cilia

b)

Chloroplasts, cell wall (cellulose), central vacuole

c)

Mitochondria, ribosomes, Rough ER

d)

Golgi apparatus, nucleolus, microtubules

6.

According to the Fluid Mosaic Model, the cell membrane is best described as a:

a)

Rigid protein layer with embedded lipids

b)

Flexible bilayer of phospholipids with embedded or attached proteins, cholesterol, and carbohydrates

c)

Single layer of phospholipids with carbohydrate tails

d)

Permeable cellulose sheet with protein pores

7.

Which statement about phospholipids in cellular membranes is accurate?

a)

They have two hydrophilic tails and a hydrophobic head

b)

They form a bilayer that is selectively permeable

c)

They function only as transport channels

d)

They are absent from prokaryotic membranes

8.

Membrane proteins can serve all of the following roles EXCEPT:

a)

Channels and carriers for transport

b)

Receptors for signaling

c)

Enzymes

d)

Sites of DNA replication

9.

Which transport process requires ATP to move substances against their concentration gradient?

a)

Simple diffusion

b)

Osmosis

c)

Facilitated diffusion

d)

Protein pumps (active transport)

10.

Facilitated diffusion differs from simple diffusion because facilitated diffusion:

a)

Moves substances from low to high concentration

b)

Requires ATP

c)

Uses specific channel or carrier proteins for larger or charged molecules

d)

Moves only water across the membrane

11.

Which statement best describes bulk transport endocytosis?

a)

A vesicle fuses with the membrane to release substances out

b)

The membrane folds inward to bring substances into the cell

c)

Ions are pumped across the membrane by ATP-driven proteins

d)

Small nonpolar molecules move down their gradient

12.

Which phase of the cell cycle includes DNA replication converting a single chromatid into a chromosome with two sister chromatids?

a)

G1 phase

b)

S phase

c)

G2 phase

d)

M phase

13.

What is the correct order of mitotic stages given their hallmark events?

a)

Metaphase — Prophase — Telophase — Anaphase

b)

Prophase — Metaphase — Anaphase — Telophase

c)

Anaphase — Telophase — Prophase — Metaphase

d)

Prophase — Anaphase — Metaphase — Telophase

14.

Mitosis results in the production of:

a)

Two genetically identical diploid daughter cells

b)

Two genetically unique diploid daughter cells

c)

Four genetically identical haploid daughter cells

d)

Four genetically unique diploid daughter cells

15.

During Meiosis I, what key event occurs?

a)

Separation of sister chromatids

b)

Separation of homologous chromosomes

c)

DNA replication

d)

Formation of two identical nuclei

16.

Which phase of the cell cycle is the longest and includes growth and preparation for division?

a)

Prophase

b)

Interphase

c)

Metaphase

d)

M Phase (Mitosis)

17.

During which subphase of interphase does DNA replication occur, converting a single chromatid into a chromosome with two sister chromatids?

a)

G1 (Gap 1)

b)

S (Synthesis)

c)

G2 (Gap 2)

d)

M Phase

18.

What is the correct order of mitosis stages described for nuclear division producing two genetically identical diploid daughter cells?

a)

Metaphase → Prophase → Anaphase → Telophase

b)

Prophase → Metaphase → Anaphase → Telophase

c)

Prophase → Anaphase → Metaphase → Telophase

d)

Metaphase → Anaphase → Telophase → Prophase

19.

Which event defines metaphase of mitosis?

a)

Chromosomes condense and nuclear envelope breaks down

b)

Chromosomes line up at the middle (metaphase plate)

c)

Sister chromatids are pulled apart to opposite poles

d)

Chromosomes decondense and two nuclei form

20.

What is the ploidy and genetic relationship of daughter cells produced by mitosis?

a)

Haploid and genetically unique

b)

Diploid and genetically identical

c)

Diploid and genetically unique

d)

Haploid and genetically identical

21.

Meiosis produces which outcome after two rounds of division?

a)

Two diploid daughter cells identical to the parent

b)

Four diploid daughter cells unique from the parent

c)

Four haploid daughter cells that are genetically unique

d)

Two haploid daughter cells identical to each other

22.

Which separation occurs in Meiosis I according to the material?

a)

Sister chromatids separate

b)

Homologous chromosomes separate

c)

Centromeres duplicate

d)

Nuclear membranes fuse

23.

What key event during Prophase I contributes directly to genetic variation?

a)

Independent assortment of sister chromatids

b)

Crossing over between homologous chromosomes

c)

Random fusion of gametes

d)

Mutation during DNA replication in G1

24.

In which meiotic stage do homologous pairs line up at the middle?

a)

Metaphase I

b)

Anaphase I

c)

Metaphase II

d)

Prophase II

25.

Which statement correctly contrasts Meiosis II with Mitosis based on the description?

a)

Both separate homologous chromosomes

b)

Meiosis II separates sister chromatids like mitosis does

c)

Mitosis separates homologous chromosomes while Meiosis II does not

d)

Neither separates sister chromatids

26.

During anaphase of mitosis, what specifically is pulled apart?

a)

Homologous chromosomes

b)

Sister chromatids

c)

Centrosomes

d)

Nuclear envelopes

27.

A cell with a diploid number (2n) completes meiosis. Which best describes the chromosome number in each resulting daughter cell?

a)

2n, identical to the parent

b)

n, identical to each other

c)

n, unique from one another

d)

2n, unique from one another

28.

Which class of biomolecules has monosaccharides as monomers and polysaccharides as polymers?

a)

Carbohydrates

b)

Lipids

c)

Proteins

d)

Nucleic acids

29.

The monomer of proteins is the amino acid, and the polymer is a polypeptide. What is a key function of proteins according to the material?

a)

Primary energy storage only

b)

Store and transmit genetic information

c)

Serve as enzymes and provide structural and defense roles

d)

Main component of cell membranes only

30.

Which polymer stores and transmits genetic information?

a)

Polysaccharide

b)

Triglyceride

c)

Polypeptide

d)

DNA or RNA

31.

Enzymes speed up chemical reactions primarily by which mechanism?

a)

Raising the activation energy

b)

Lowering the activation energy

c)

Increasing the product concentration

d)

Consuming substrate as fuel

32.

What is the active site of an enzyme?

a)

The region that binds inhibitors

b)

The region that binds the substrate

c)

A separate protein that activates enzymes

d)

The site where products are released only

33.

Each enzyme has an optimal pH. What is the effect of extreme pH (too acidic or too basic)?

a)

It causes saturation

b)

It increases substrate concentration

c)

It causes denaturation

d)

It has no effect on enzymes

34.

How does increasing substrate concentration affect reaction rate before saturation?

a)

The rate decreases steadily

b)

The rate remains constant

c)

The rate increases until all active sites are busy

d)

The rate instantly reaches maximum and stays there

35.

Which of the following pairs correctly matches a biomolecule with one of its listed functions?

a)

Carbohydrates: long-term insulation

b)

Lipids: main component of cell membranes and long-term energy storage

c)

Proteins: store genetic information

d)

Nucleic acids: primary source of energy

36.

Which example is a carbohydrate polymer noted for plant energy storage?

a)

Cellulose

b)

Starch

c)

Glycogen

d)

Cholesterol

37.

A reaction mixture contains an enzyme working at its optimal temperature and pH. Substrate concentration is gradually increased. Which observation is expected at high substrate concentration according to the material?

a)

Enzyme rate drops due to denaturation

b)

Enzyme activity becomes limited by product formation only

c)

The enzyme becomes saturated and the rate levels off

d)

The enzyme changes its amino acid sequence to improve binding

38.

Which statement distinguishes lipids from the other listed biomolecules in the material?

a)

They are true polymers built from repeating monomers

b)

They are not true polymers and are grouped by hydrophobicity

c)

They store and transmit genetic information

d)

Their monomers are nucleotides

39.

Which equation best represents photosynthesis as described?

a)

C6H12O6 + 6O2 → 6CO2 + 6H2O + ATP

b)

6CO2 + 6H2O + light energy → C6H12O6 + 6O2

c)

6O2 + C6H12O6 → 6CO2 + 6H2O + light energy

d)

CO2 + H2O → CH4 + O2

40.

Where do the light-dependent reactions of photosynthesis occur?

a)

Stroma

b)

Cytoplasm

c)

Thylakoid membranes

d)

Mitochondrial matrix

41.

Which product is generated directly by the light-dependent reactions for use in the Calvin cycle?

a)

Glucose

b)

Pyruvate

c)

ATP and NADPH

d)

Acetyl-CoA

42.

Which statement correctly describes the Calvin cycle according to the material?

a)

It splits water to release O2

b)

It uses CO2 and ATP/NADPH to build organic molecules

c)

It occurs in thylakoid membranes

d)

It generates most ATP by chemiosmosis

43.

Which is the correct overall equation for cellular respiration given?

a)

6CO2 + 6H2O + ATP → C6H12O6 + 6O2

b)

C6H12O6 + 6O2 → 6CO2 + 6H2O + ATP

c)

C6H12O6 → ethanol + CO2

d)

6O2 → 6H2O + ATP

44.

Which stage of cellular respiration happens in the cytoplasm and is anaerobic?

a)

Glycolysis

b)

Pyruvate oxidation

c)

Krebs cycle

d)

Oxidative phosphorylation

45.

What is the net gain from glycolysis per glucose molecule as listed?

a)

4 ATP and 2 NADH

b)

2 ATP and 2 NADH

c)

2 ATP and 4 NADH

d)

0 ATP and 2 NADH

46.

Pyruvate oxidation converts each pyruvate into which molecule?

a)

Glucose

b)

Acetyl-CoA

c)

Lactic acid

d)

Ethanol

47.

Per glucose, which outputs are associated with the Krebs cycle in the notes?

a)

2 ATP, 6 NADH, 2 FADH2, 4 CO2

b)

2 ATP only

c)

28–34 ATP

d)

Lactic acid and 2 ATP

48.

During oxidative phosphorylation, which molecule acts as the final electron acceptor?

a)

Carbon dioxide

b)

NAD+

c)

Oxygen (forming H2O)

d)

FAD

49.

What drives ATP synthesis as H+ ions flow back through ATP synthase?

a)

Substrate-level phosphorylation in the cytosol

b)

Energy from breaking glucose directly

c)

Proton gradient across the inner mitochondrial membrane

d)

Electron flow through chlorophyll

50.

Which fermentation type is correctly matched with its typical organism/example?

a)

Alcoholic fermentation — animals

b)

Lactic acid fermentation — yeast

c)

Lactic acid fermentation — animals and bacteria

d)

Alcoholic fermentation — plants only

51.

Approximately how many ATP are produced during oxidative phosphorylation according to the text?

a)

2

b)

4

c)

10–12

d)

Around 28–34

52.

Which best describes ATP structure?

a)

Ribose, adenine, and two phosphate groups

b)

Deoxyribose, adenine, and three phosphate groups

c)

Adenine, a ribose sugar, and three phosphate groups

d)

Guanine, deoxyribose, and three phosphate groups

53.

Energy is released for cellular work when which bond(s) of ATP are broken by hydrolysis?

a)

Between adenine and ribose

b)

Between the 2nd and 3rd phosphate groups

c)

Between ribose and first phosphate only

d)

Only within the nitrogenous base

54.

What is the term for ATP regeneration from ADP and inorganic phosphate using energy from cellular respiration?

a)

Photolysis

b)

Phosphorylation

c)

Carboxylation

d)

Reduction

55.

During photosynthesis, which molecule is split to release oxygen gas?

a)

CO2

b)

Glucose

c)

Water

d)

NADPH

56.

Which statement best describes the overall flow of genetic information in the central dogma of biology?

a)

Protein → RNA → DNA

b)

DNA → RNA → Protein

c)

RNA → DNA → Protein

d)

DNA → Protein → RNA

57.

Which base pairing rule is correct for DNA?

a)

A pairs with C; G pairs with T

b)

A pairs with T; G pairs with C

c)

A pairs with U; G pairs with C

d)

A pairs with G; T pairs with C

58.

During DNA replication, which enzyme is primarily responsible for adding new complementary nucleotides to the template strand?

a)

Helicase

b)

Ligase

c)

DNA Polymerase

d)

RNA Polymerase

59.

What does it mean that DNA replication is semiconservative?

a)

Each new DNA molecule contains two new strands.

b)

Each new DNA molecule contains one old and one new strand.

c)

Only the leading strand is copied.

d)

Replication occurs without enzymes.

60.

Which statement distinguishes the leading and lagging strands during DNA replication?

a)

Both are synthesized continuously from 3' to 5'.

b)

Leading is discontinuous; lagging is continuous.

c)

Leading is synthesized continuously 5'→3'; lagging is synthesized discontinuously in Okazaki fragments.

d)

Both are synthesized discontinuously in Okazaki fragments.

61.

Which enzyme joins Okazaki fragments on the lagging strand?

a)

Helicase

b)

Ligase

c)

Topoisomerase

d)

Primase

62.

Which base in RNA replaces thymine (T) found in DNA during transcription?

a)

Cytosine (C)

b)

Uracil (U)

c)

Adenine (A)

d)

Guanine (G)

63.

What is the role of RNA polymerase during transcription?

a)

Joins Okazaki fragments

b)

Binds to a gene's promoter, unzips DNA, and adds complementary RNA nucleotides

c)

Transports amino acids to the ribosome

d)

Synthesizes DNA from RNA

64.

Which component carries the genetic message from the nucleus to the ribosome?

a)

tRNA

b)

mRNA

c)

rRNA

d)

DNA

65.

During translation, what is the function of tRNA?

a)

Serves as the workbench for protein synthesis

b)

Carries codons to the nucleus

c)

Has an anticodon that matches an mRNA codon and carries a specific amino acid

d)

Synthesizes mRNA from DNA

66.

Which term best describes ribosomes in the context of protein synthesis?

a)

Genetic message

b)

Translator

c)

Workbench

d)

Promoter

67.

Which of the following is a defining structural feature of DNA?

a)

Single-stranded with ribose sugar

b)

Double helix with a sugar-phosphate backbone

c)

Triple helix with deoxyribose sugar

d)

Double helix with uracil

68.

Antiparallel orientation of DNA strands means:

a)

Both strands run 5' to 3'.

b)

One strand runs 5' to 3' while the other runs 3' to 5'.

c)

Both strands run 3' to 5'.

d)

Strands run parallel in the same direction.

69.

Which sequence correctly matches a point mutation subtype with its effect?

a)

Silent: changes amino acid codon to a stop codon

b)

Missense: results in a different amino acid

c)

Nonsense: no change in the amino acid

d)

Frameshift: swaps one base for another without insertion/deletion

70.

Which statement about chromosomal mutations is supported by the material?

a)

They involve a single base pair change.

b)

They include deletion, duplication, inversion, and translocation.

c)

They always result in a silent effect.

d)

They are the same as point mutations.

71.

In autosomal recessive disorders, which genotype description is accurate according to the material?

a)

One copy of the dominant allele (Aa) is sufficient to be affected.

b)

Carriers (Aa) are healthy, and two recessive alleles (aa) are required to be affected.

c)

Only AA individuals are affected.

d)

Heterozygotes (Aa) show full disease expression and are not carriers.

72.

Which statement best defines a mutation?

a)

A temporary change in protein shape

b)

A permanent change in the DNA sequence

c)

A random change in RNA after translation

d)

A change in phenotype without genotype change

73.

Which point mutation replaces one base with another without altering the amino acid sequence?

a)

Missense substitution

b)

Nonsense substitution

c)

Silent substitution

d)

Frameshift insertion

74.

A single-base insertion that shifts the reading frame most directly leads to which outcome?

a)

No change in protein length

b)

Truncation at a stop codon with same frame

c)

Usually a nonfunctional protein due to altered codons

d)

Creation of a synonymous codon only

75.

Which is NOT listed as a chromosomal mutation type?

a)

Deletion

b)

Inversion

c)

Translocation

d)

Base substitution

76.

For an autosomal recessive disorder, which genotype represents a healthy carrier?

a)

aa

b)

AA

c)

Aa

d)

aAaa

77.

Which inheritance pattern requires only one copy of the mutant allele (AA or Aa) to express the disease?

a)

Autosomal recessive

b)

Autosomal dominant

c)

Polygenic

d)

Mitochondrial

78.

Sex-linked recessive traits are more common in which group and why?

a)

Females, because they have two X chromosomes

b)

Males, because they have only one X chromosome ( XAX^A Y)

c)

Females, due to X-inactivation

d)

Males, due to Y-linked inheritance

79.

Nondisjunction during meiosis most likely results in which condition listed?

a)

Sickle-cell anemia

b)

Hemophilia

c)

Down Syndrome (Trisomy 21)

d)

Cystic Fibrosis

80.

Which term describes the observable traits of an organism, such as tall or short?

a)

Genotype

b)

Phenotype

c)

Allele

d)

Anticodon

81.

According to the law of segregation, when do the two alleles for a trait separate?

a)

During mitosis

b)

During fertilization

c)

During gamete formation (meiosis)

d)

During DNA replication

82.

In a monohybrid cross of Tt × Tt, what is the expected phenotypic ratio stated?

a)

1:2:1

b)

3:1

c)

9:3:3:1

d)

2:1

83.

Which statement best distinguishes incomplete dominance from co-dominance?

a)

Incomplete dominance shows a blended heterozygous phenotype; co-dominance fully and equally expresses both alleles

b)

Both express only the dominant allele in heterozygotes

c)

Incomplete dominance equally expresses both alleles; co-dominance blends them

d)

Both produce identical phenotypes to homozygotes

84.

Which example illustrates co-dominance as described?

a)

Pink flowers from red × white

b)

Blood type AB expressing both A and B antigens

c)

Tall plants from TT genotype

d)

Colorblindness in males

85.

Under the Hardy-Weinberg principle, allele frequencies remain constant between generations if the population meets the required conditions. Which set includes two listed conditions for equilibrium?

a)

No mutations and random mating

b)

Natural selection and small population

c)

Migration and nonrandom mating

d)

Genetic drift and assortative mating

86.

Which statement best describes an allele?

a)

An observable trait of an organism

b)

An alternative form of a gene

c)

A diagram predicting offspring ratios

d)

The complete genetic makeup of an organism

87.

According to the Law of Segregation, what happens during gamete formation?

a)

Alleles for different traits sort independently

b)

Two alleles for a trait separate

c)

Chromosomes fail to separate

d)

Mutations increase genetic variation

88.

In a monohybrid cross following Mendelian inheritance, what is the typical phenotypic ratio among the offspring?

a)

1:1

b)

3:1

c)

9:3:3:1

d)

1:2:1

89.

Which condition is NOT required for Hardy-Weinberg equilibrium?

a)

Random mating

b)

No natural selection

c)

Small population size

d)

No gene flow (migration)

90.

If p represents the frequency of the dominant allele and q represents the frequency of the recessive allele in a population, which equation must always hold under Hardy-Weinberg assumptions?

a)

p + q = 0

b)

p2+2pq+q2=0p^2 + 2pq + q^2 = 0

c)

p + q = 1

d)

p2+q2=1p^2 + q^2 = 1

91.

The heterozygous phenotype is a blend of the two homozygous phenotypes. Which non-Mendelian pattern is this?

a)

Co-dominance

b)

Incomplete dominance

c)

Polygenic inheritance

d)

Sex-linked recessive

92.

Which scenario illustrates co-dominance?

a)

Pink flowers from red and white parents

b)

Tall plants resulting from two short parents

c)

AB blood type expressing both A and B antigens

d)

A continuous range of skin colors

93.

Polygenic inheritance typically results in which pattern of phenotypes?

a)

Discrete categories

b)

A continuous range

c)

Only two possible outcomes

d)

Lethal alleles only

94.

Which symbol is used to represent a female in a pedigree chart?

a)

Square

b)

Circle

c)

Triangle

d)

Diamond

95.

In pedigree analysis, what does a half-shaded symbol indicate?

a)

Affected individual

b)

Unaffected individual

c)

Carrier (known heterozygote)

d)

Proband

96.

Which biotechnology tool acts as "molecular scissors" that cut DNA at specific recognition sites?

a)

Polymerase Chain Reaction (PCR)

b)

Restriction enzymes

c)

Gel electrophoresis

d)

CRISPR-Cas9

97.

What is the primary purpose of PCR?

a)

Separating DNA fragments by size

b)

Cutting DNA at specific sites

c)

Making many copies of a specific DNA segment

d)

Combining DNA from different sources

98.

During gel electrophoresis, which fragments move faster and further through the gel?

a)

Larger fragments

b)

Smaller fragments

c)

Fragments with no charge

d)

Circular plasmids only

99.

Which statement about CRISPR-Cas9 is accurate?

a)

It is a vector used to carry genes into host cells

b)

It is a technique to amplify DNA non-specifically

c)

It allows precise cutting and modifying of DNA sequences

d)

It separates DNA fragments by size

100.

Which description best matches a plasmid in biotechnology?

a)

A large linear chromosome used for replication

b)

A small circular DNA used as a vector in bacteria

c)

An RNA molecule that edits genes

d)

A protein complex that cuts DNA

101.

A population’s allele frequencies remain constant across generations when certain conditions are met. What does this statement define?

a)

Law of Independent Assortment

b)

Hardy-Weinberg Principle

c)

Polygenic inheritance

d)

Genetic drift

102.

Which Mendelian principle states that alleles for different traits sort independently of one another?

a)

Law of Segregation

b)

Law of Independent Assortment

c)

Linkage

d)

Non-disjunction

103.

Sex-linked recessive traits are typically more common in which group and why?

a)

Females, because they have two X chromosomes

b)

Males, because they have only one X chromosome

c)

Females, due to mitochondrial inheritance

d)

Males, because of Y-linked dominance

104.

Which example best illustrates nondisjunction?

a)

AB blood type in humans

b)

Pink flowers from red and white parents

c)

Down syndrome (Trisomy 21) due to failure of chromosome separation

d)

A trait controlled by two or more genes

105.

Which pairing correctly matches a technique with its function?

a)

Recombinant DNA — separating DNA fragments by size

b)

Gel electrophoresis — amplifying DNA

c)

PCR — combining DNA from two sources

d)

CRISPR-Cas9 — precise gene editing

106.

Which is the correct genotype frequency expression under Hardy-Weinberg equilibrium?

a)

p2+2pq+q2=1p^2 + 2pq + q^2 = 1

b)

p + q = 1

c)

p2+pq+q2=1p^2 + pq + q^2 = 1

d)

2p + 2q = 1

107.

Which statement defines a gene pool?

a)

The total number of individuals in a population

b)

All the alleles for all the genes in a population

c)

How common a trait is in a population

d)

Only dominant alleles present in a population

108.

Which description best fits a phenotype?

a)

The genetic makeup of an organism

b)

The physical, observable trait

c)

Two identical alleles

d)

A heterozygous genotype

109.

What is evolution as defined in this section?

a)

The appearance of new species in a single generation

b)

Change in allele frequencies in a population over time

c)

Random mating in large populations

d)

The process of DNA replication

110.

In a dihybrid cross tracking two traits, what is the typical phenotypic ratio expected under independent assortment?

a)

3:1

b)

1:2:1

c)

9:3:3:1

d)

1:1:1:1

111.

Which statement best defines evolution as presented in the material?

a)

The appearance of new species in a single generation

b)

The change in allele frequencies in a population over time

c)

The survival of the fastest individuals regardless of genetics

d)

The transformation of individuals during their lifetime

112.

According to the principles of natural selection, which sequence lists the four key components in the correct logical order?

a)

Variation → Overproduction → Differential Survival & Reproduction → Struggle for Existence

b)

Overproduction → Variation → Struggle for Existence → Differential Survival & Reproduction

c)

Struggle for Existence → Overproduction → Variation → Differential Survival & Reproduction

d)

Differential Survival & Reproduction → Struggle for Existence → Overproduction → Variation

113.

Which outcome is expected over generations as a result of natural selection?

a)

Decrease in advantageous alleles

b)

Increase in harmful mutations only

c)

Stable allele frequencies regardless of environment

d)

Increase in the frequency of advantageous alleles

114.

Which feature distinguishes prokaryotic DNA from eukaryotic DNA in the comparison chart?

a)

Prokaryotic DNA is linear and in the nucleus; eukaryotic DNA is circular in the cytoplasm

b)

Prokaryotic DNA is circular in the cytoplasm; eukaryotic DNA is linear in the nucleus

c)

Both have linear DNA in the cytoplasm

d)

Both have circular DNA in the nucleus

115.

Which cell type contains membrane-bound organelles according to the table?

a)

Prokaryote

b)

Eukaryote

c)

Both prokaryote and eukaryote

d)

Neither prokaryote nor eukaryote

116.

Which process describes cell division in prokaryotes?

a)

Meiosis

b)

Mitosis

c)

Binary fission

d)

Budding

117.

Which organisms are listed as examples of prokaryotes?

a)

Animals and plants

b)

Bacteria and Archaea

c)

Fungi and plants

d)

Animals and fungi

118.

In the comparison table, which ribosome size is associated with eukaryotes?

a)

70S

b)

80S

c)

50S

d)

30S

119.

Which statement about the nucleus is accurate based on the chart?

a)

Prokaryotes have a nucleus; eukaryotes do not

b)

Both prokaryotes and eukaryotes lack a nucleus

c)

Eukaryotes have a nucleus; prokaryotes lack a nucleus (have nucleoid)

d)

Only prokaryotes have multiple nuclei

120.

Which principle of natural selection explains why not all offspring survive to reproduce?

a)

Variation

b)

Overproduction

c)

Differential Survival & Reproduction (Fitness)

d)

Result of evolution

121.

Which stage of cell signaling involves a ligand binding to a specific receptor protein?

a)

Reception

b)

Transduction

c)

Response

d)

Amplification

122.

During transduction in cell signaling, what commonly occurs within the cell?

a)

Ligand synthesis

b)

Signal transduction pathway such as a phosphorylation cascade

c)

Exocytosis of receptors

d)

DNA replication

123.

Which outcome best represents the response stage of cell signaling?

a)

Ligand binding

b)

Second messenger formation

c)

Gene expression or protein activation

d)

Receptor endocytosis

124.

Intracellular receptors most likely bind which type of ligand?

a)

Large hydrophilic peptides

b)

Ions that cannot cross membranes

c)

Small hydrophobic molecules like steroid hormones

d)

Neurotransmitters that require vesicles

125.

Cell-surface receptors typically bind ligands that are:

a)

Hydrophobic and membrane-permeable

b)

Hydrophilic and cannot cross the membrane

c)

Covalently attached to transport proteins

d)

Only gases like O2 and CO2

126.

Which is an example of negative feedback described in the material?

a)

Blood clotting

b)

Childbirth contractions increasing

c)

Sweating to cool down when hot

d)

Oxytocin release during labor

127.

Positive feedback differs from negative feedback because it:

a)

Reduces system instability

b)

Amplifies or reinforces the initial stimulus

c)

Maintains a constant set point

d)

Stops once homeostasis is restored

128.

Which blood component is correctly matched with its function according to the material?

a)

Plasma: cell fragments that clot

b)

Red blood cells: contain hemoglobin to transport O2

c)

White blood cells: carry CO2

d)

Platelets: part of the immune system

129.

Which heart chambers receive blood?

a)

Right and left ventricles

b)

Right and left atria

c)

Left atrium and right ventricle

d)

Only the right atrium

130.

Which vessel type carries blood away from the heart and typically has thick, muscular walls?

a)

Veins

b)

Capillaries

c)

Arteries

d)

Venules

131.

What structural feature of veins helps prevent backflow of blood?

a)

Thick muscular walls

b)

Valves

c)

One-cell-thick walls

d)

Elastic lamellae only

132.

Where does gas and nutrient exchange primarily occur within the circulatory system?

a)

Aorta

b)

Capillaries

c)

Pulmonary artery

d)

Vena cava

133.

Which sequence correctly traces the pulmonary circuit described?

a)

Right atrium → Right ventricle → Aorta → Lungs → Pulmonary vein

b)

Right ventricle → Pulmonary artery → Lungs → Pulmonary vein → Left atrium

c)

Left ventricle → Pulmonary artery → Lungs → Pulmonary vein → Right atrium

d)

Right ventricle → Aorta → Lungs → Pulmonary vein → Left ventricle

134.

Which structure is the primary site where gas exchange occurs in the lungs?

a)

Trachea

b)

Bronchi

c)

Bronchioles

d)

Alveoli

135.

Gas exchange across alveolar and capillary walls occurs mainly by which process?

a)

Active transport

b)

Osmosis

c)

Simple diffusion

d)

Facilitated diffusion

136.

During inhalation, which muscle action directly allows air to rush into the lungs?

a)

Diaphragm relaxes and chest cavity shrinks

b)

Diaphragm contracts and chest cavity expands

c)

Rib muscles relax and chest cavity expands

d)

Abdominal muscles contract and pressure increases

137.

Which statement best describes oxygen movement in the lungs during gas exchange?

a)

O2 diffuses from blood into the alveoli

b)

O2 diffuses from alveoli into the blood

c)

O2 is pumped into blood by active transport

d)

O2 binds CO2 to enter the blood

138.

What is the main function of the respiratory system as described?

a)

Exchange nutrients with tissues

b)

Transport hormones

c)

Take in O2 and release CO2

d)

Generate electrical impulses

139.

Which sequence correctly traces the path of air from entry to the site of gas exchange?

a)

Pharynx → Nose/Mouth → Larynx → Alveoli

b)

Nose/Mouth → Pharynx → Larynx → Trachea → Bronchi → Bronchioles → Alveoli

c)

Mouth → Esophagus → Stomach → Alveoli

d)

Trachea → Larynx → Pharynx → Bronchi → Alveoli

140.

Which description correctly matches exhalation with muscle activity and chest cavity changes?

a)

Active process; diaphragm contracts, pressure drops

b)

Passive process; diaphragm and rib muscles relax, pressure rises

c)

Active process; rib muscles contract, pressure rises

d)

Passive process; diaphragm contracts, chest cavity expands

141.

Which is the primary function of the digestive system?

a)

Deliver oxygen to tissues

b)

Protect against pathogens

c)

Mechanical and chemical breakdown of food for absorption

d)

Coordinate all body functions via hormones

142.

Which process propels food through the esophagus to the stomach?

a)

Ciliary movement

b)

Peristalsis

c)

Active pumping

d)

Simple diffusion

143.

Which pairing of organ and digestive function is correct?

a)

Stomach—chemical digestion of carbohydrates by amylase

b)

Mouth—mechanical digestion and chemical digestion of carbohydrates by salivary amylase

c)

Large intestine—primary site of chemical digestion

d)

Small intestine—stores bile for later use

144.

Which statement about the small intestine is accurate?

a)

It is the primary site of water absorption only

b)

It receives bile to emulsify fats and pancreatic enzymes to digest biomolecules

c)

It stores feces for elimination

d)

It digests proteins only using pepsin

145.

What structural features increase the small intestine’s surface area for absorption?

a)

Rugae

b)

Villi and microvilli

c)

Goblet cells

d)

Cilia

146.

Which accessory organ stores bile?

a)

Liver

b)

Gallbladder

c)

Pancreas

d)

Appendix

147.

Which characteristic distinguishes the nervous system’s signaling from the endocrine system’s?

a)

Uses chemical hormones released into blood

b)

Signals are long-lasting

c)

Uses electrical impulses and chemical neurotransmitters; very fast and short-lived

d)

Organized solely as glands

148.

Which structure is the key link integrating the nervous and endocrine systems by controlling the pituitary gland?

a)

Thyroid

b)

Hypothalamus

c)

Adrenal cortex

d)

Cerebellum

149.

Which description of innate immunity is most accurate?

a)

A slow, specific response that remembers pathogens

b)

First line of defense including skin and mucous membranes with phagocytes and inflammation

c)

Antibody production by T-cells

d)

Requires prior exposure to be effective

150.

In adaptive immunity, which cells mediate the humoral response?

a)

Macrophages

b)

Neutrophils

c)

B-cells

d)

Helper T-cells only