wayground logo

Free Printable Worksheets

Font size

S
M
L
XL
Worksheets

Dental Cholinergic, anticholinesterase and antimuscarinic agents

Total questions: 20

Worksheet time: 11mins

Name
Class
Date
1.

Which of the following best describes the action of pilocarpine ?

a)

Blocks muscarinic M3 receptors in salivary glands

b)

Stimulates muscarinic M3 receptors to increase salivary secretion

c)

Stimulates muscarinic M1 receptor promoting salivation

d)

Blocks nicotinic NM receptors at neuromuscular junctions

2.

Bethanechol is useful for patients with urinary retention after anaesthesia using atropine-containing premedication.

a)

True

b)

False

3.

Which of the following cholinergic agonists is most likely to cause bronchospasm?

a)

Cevimeline

b)

Bethanechol

c)

Pilocarpine

d)

Neostigmine

4.

Indirect-acting cholinergic agonists can increase salivation by preventing ACh breakdown.

a)

True

b)

False

5.

Which drug reverses atropine overdose?

a)

Physostigmine

b)

Neostigmine

c)

Carbachol

d)

Pilocarpine

6.

Possible adverse effects of cholinergic agonists

a)

Excessive sweating

b)

Bradycardia

c)

Dry mouth

d)

urinary retention

7.

Which receptor subtype mediates M3-induced salivary secretion?

a)

G protein Gs → ↑ cAMP

b)

G protein Gq → ↑ Ca²⁺, IP₃/DAG

c)

Gi → ↓ cAMP

d)

Ligand-gated Na⁺

8.

Which muscarinic receptor antagonist is most likely to cause xerostomia in dental patients?

a)

Atropine

b)

Ipratropium

c)

Benztropine

d)

Oxybutynin

9.

Scopolamine is commonly used to prevent headache during long transport.

a)

True

b)

False

10.

A dental patient taking oxybutynin for urinary incontinence complains of difficulty wearing dentures due to dry mouth. What explains this?

a)

Sympathomimetic effect

b)

Muscarinic stimulation

c)

Muscarinic blockade

d)

Nicotinic activation

11.

Select the likely adverse effects of systemic antimuscarinic use relevant to oral health:

a)

Xerostomia

b)

Dysphagia

c)

Miosis 

d)

Tachycardia

12.

During a restorative dental procedure, atropine was given to reduce salivation. Which ocular side effect may the patient report?

a)

Blurred near vision and photophobia

b)

Pupil constriction

c)

Improved oral hygiene

d)

Lacrimation

13.

Ipratropium bromide produces CNS excitation similar to atropine.

a)

True

b)

FAlse

14.

Which antimuscarinic is preferred to reduce salivation before oral surgery without CNS effects?

a)

Scopolamine

b)

Atropine

c)

Glycopyrrolate

d)

Benztropine

15.

Which of the following are contraindications for antimuscarinic use?

a)

Glaucoma

b)

Asthma

c)

Prostatic hypertrophy

d)

Hypertension

16.

Benztropine improves Parkinson’s rigidity by blocking central M1 receptors.

a)

True

b)

FAlse

17.

A dental patient on donepezil for Alzheimer’s disease experiences excessive salivation during scaling.
What is the pharmacological explanation?

a)

Increased acetylcholinesterase activity

b)

Inhibition of acetylcholinesterase

c)

Inhibition of dopamine reuptake

d)

Blockade of nicotinic receptors

18.

Which of the following best explains why neostigmine cannot reverse atropine toxicity in the CNS?

a)

It is metabolized too quickly

b)

It cannot cross the blood–brain barrier

c)

It lacks affinity for muscarinic receptors

d)

It binds irreversibly to acetylcholinesterase

19.

Dental implications of antimuscarinic drug use include:

a)

Difficulty wearing dentures

b)

Altered taste

c)

Delayed wound healing

d)

Increased dental plaque

20.

An elderly female presents with rampant caries and a medication list that includes benztropine and oxybutynin.What is the primary oral diagnosis linked to her medications?

a)

Mucositis

b)

Xerostomia

c)

Candidiasis

d)

.Tooth erosion