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Adrenergic & Antiadrenergic Batch C

Total questions: 20

Worksheet time: 23mins

Name
Class
Date
1.

Choose the single best response: Norepinephrine increases:

a)

Heart rate

b)

Blood pressure

c)

Bronchodilation

d)

GI motility

2.

Choose the single best response: Which of the following drug is a third generation β-blocker?

a)

Propranolol

b)

Timolol

c)

Nadolol

d)

Nebivolol

3.

Choose the single best response: A patient in shock comes to you in trauma ward. You examine him and decide not to give him vasoconstrictors. Which is the type of shock your patient is having?

a)

Neurogenic shock

b)

Haemorrhagic shock

c)

Secondary shock

d)

Hypotension due to spinal anaesthesia

4.

Choose the single best response: Beta adrenergic blockers lower intraocular tension by:

a)

Down regulating adenylyl cyclase in ciliary body through reduced activation of β2 receptors

b)

Constricting ciliary blood vessels

c)

Blocking adrenergic action on trabecular meshwork

d)

Reducing aqueous formation unrelated to beta adrenoceptor mediation

5.

Choose the single best response: The primary reason for preferring phentolamine as the α adrenergic blocker for performing diagnostic test for pheochromocytoma is:

a)

It produces rapid and short lasting α-adrenergic blockade

b)

It equally blocks α1 and α2 adrenoceptors

c)

It is the most potent α blocker

d)

It has no additional β adrenergic blocking property

6.

Choose the single best response: Select the drug which can improve urinary flow rate in benign prostatic hypertrophy without affecting prostate size:

a)

Amphetamine

b)

Prazosin

c)

Finasteride

d)

Goserelin

7.

Choose the single best response: Select the drug which can impair carbohydrate tolerance in prediabetics but prolongs insulin hypoglycaemia:

a)

Salbutamol

b)

Propranolol

c)

Prazosin

d)

Nifedipine

8.

Choose the correct responses (Multiple options maybe right). Uses of α-blockers: (Select 2)

a)

Pheochromocytoma

b)

BPH

c)

Migraine

d)

Arrhythmias

9.

Choose the correct responses (Multiple options maybe right). Clonidine has the following attributes except:

a)

Acts on α2 adrenergic receptors

b)

Can produce rebound hypertension on abrupt withdrawal

c)

Can produce CNS stimulation

d)

Increases salivation

10.

Choose the correct responses (Multiple options maybe right). Contraindications of beta blockers are:

a)

Asthma

b)

Heart block

c)

Hypertension

d)

Myocardial Infarction

11.

Assertion–Reason: Assertion: Phenylephrine produces mydriasis. Reason: It causes contraction of radial (dilator) muscle of iris via α1 stimulation.

a)

Both Assertion and Reason are true, and Reason explains Assertion.

b)

Both Assertion and Reason are true, but Reason does not explain Assertion.

c)

Assertion is true, Reason is false.

d)

Assertion is false, Reason is true.

12.

Assertion–Reason: Assertion: Methylphenidate is preferred over amphetamine in the management of Attention-Deficit/Hyperactivity Disorder (ADHD). Reason: Methylphenidate has a lower risk of abuse and dependence compared to amphetamine.

a)

Both Assertion and Reason are true, and Reason explains Assertion.

b)

Both Assertion and Reason are true, but Reason does not explain Assertion.

c)

Assertion is true, Reason is false.

d)

Assertion is false, Reason is true.

13.

Assertion–Reason: Assertion: Tamsulosin relieves urinary obstruction in benign prostatic hyperplasia. Reason: Tamsulosin does not significantly lower blood pressure.

a)

Both Assertion and Reason are true, and Reason explains Assertion.

b)

Both Assertion and Reason are true, but Reason does not explain Assertion.

c)

Assertion is true, Reason is false.

d)

Assertion is false, Reason is true.

14.

Assertion: Betaxolol is preferred in glaucoma patients who also have respiratory disease Reason: Betaxolol relieves glaucoma by blocking α₁-adrenergic receptors in the eye.

a)

Both true, reason explains assertion

b)

Both true, reason does not explain assertion

c)

Assertion true, reason false

d)

Both false

15.

Assertion: Salbutamol is used in preterm labor. Reason: It relaxes uterine smooth muscle via β2 receptors.

a)

Both true, reason explains assertion

b)

Both true, reason does not explain assertion

c)

Assertion true, reason false

d)

Both false

16.

Case: A 24-year-old woman is brought to the emergency department 10 minutes after receiving an injection for fever. She suddenly develops difficulty in breathing, wheezing, swelling of lips and tongue, intense itching, dizziness, and a fall in blood pressure. Her pulse is feeble and rapid. She is suspected to be in anaphylactic shock. The drug of choice for the immediate management of this patient is:

a)

Hydrocortisone

b)

Chlorpheniramine

c)

Adrenaline

d)

Salbutamol

17.

Case: A 24-year-old woman is brought to the emergency department 10 minutes after receiving an injection for fever. She suddenly develops difficulty in breathing, wheezing, swelling of lips and tongue, intense itching, dizziness, and a fall in blood pressure. Her pulse is feeble and rapid. She is suspected to be in anaphylactic shock. The preferred route of administration of this drug in this emergency is:

a)

Oral

b)

Intravenous bolus

c)

Intramuscular

d)

Subcutaneous

18.

Case: A 24-year-old woman is brought to the emergency department 10 minutes after receiving an injection for fever. She suddenly develops difficulty in breathing, wheezing, swelling of lips and tongue, intense itching, dizziness, and a fall in blood pressure. Her pulse is feeble and rapid. She is suspected to be in anaphylactic shock. The most important life-saving action of adrenaline in anaphylaxis is:

a)

Increased urine output

b)

Bronchodilation and rise in blood pressure

c)

Sedation of the patient

d)

Antipyretic action

19.

Case: A 24-year-old woman is brought to the emergency department 10 minutes after receiving an injection for fever. She suddenly develops difficulty in breathing, wheezing, swelling of lips and tongue, intense itching, dizziness, and a fall in blood pressure. Her pulse is feeble and rapid. She is suspected to be in anaphylactic shock. Adrenaline produces bronchodilation mainly by stimulating:

a)

α1 receptors

b)

α2 receptors

c)

β1 receptors

d)

β2 receptors

20.

After initial management, which class of drugs is commonly added to prevent a delayed reaction?

a)

Antipyretics

b)

Corticosteroids

c)

Diuretics

d)

Antacids