WorksheetsPRCBB_2MT-P7
Total questions: 73
Worksheet time: 37mins
Name
Class
Date
1.
Kell antigens or genes are found on which chromosome?
a)
Chromosome 5
b)
Chromosome 6
c)
Chromosome 7
d)
Chromosome 1
2.
Which antigen is second to D in terms of immunogenicity?
a)
Kell
b)
Kidd
c)
Lutheran
3.
Which antigen is not denatured by the routine blood bank enzymes ficin and papain but are destroyed by trypsin and chymotrypsin when used in combination?
a)
Kell
b)
Kidd
c)
Lutheran
4.
Which blood bank enzymes does not denature Kell?
a)
Ficin
b)
Trypsin
c)
Chymotrypsin
d)
Papain
5.
Which blood bank enzymes destroys Kell when used together?
a)
Ficin
b)
Trypsin
c)
Chymotrypsin
d)
Papain
6.
Lack all Kell system antigens but the RBCs have increased _ antigen
a)
K0 or K null phenotype
b)
Kx Antigen
7.
This has no RBC membrane abnormality
a)
K0 or K null phenotype
b)
Kx Antigen
8.
Which of the following is present on ALL RBCs EXCEPT those of the rare Mcleod phenotype?
a)
K0 or K null phenotype
b)
Kx Antigen
9.
When Kell antigens are denatured with AET or DTT, the expression of this increases
a)
K0 or K null phenotype
b)
Kx Antigen
10.
This is a precursor of the Kell antigen, responsible for synthesis and formation of Kell antigen
a)
K0 or K null phenotype
b)
Kx Antigen
11.
WBCs of this remains unconverted, while RBCs of this is converted to Kell antigen
a)
K0 or K null phenotype
b)
Kx Antigen
12.
Chronic granulomatous disease lacks leukocytic __ antigen. Hence, this condition is characterized by inability of the neutrophil to kill ingested bacteria.
a)
K0 or K null phenotype
b)
Kx Antigen
13.
Which of the following diseases is associated with lack of leukocytic Kx antigen and inability of the neutrophil to kill ingested bacteria?
a)
Chronic myeloid disease
b)
Chronic granulomatous disease
c)
Chronic myelogenous leukemia disease
14.
Which of the following part of the Kx antigen remains unconverted?
a)
WBCs
b)
RBCs
c)
PLT
d)
Hct
e)
Hgb
15.
Which of the following part of the Kx antigen is converted to Kell antigen?
a)
WBCs
b)
RBCs
c)
PLT
d)
Hct
e)
Hgb
16.
Kell antigens are considered as..
a)
Common
b)
Rare
c)
Not common but not that rare as well
d)
NOTA
e)
AOTA
17.
Are Kell antigens well developed at birth?
a)
Yes
b)
No
c)
Maybe
d)
I don't know
18.
RBCs lack Kx and the Kell system high prevalence antigen Km, and have marked depression of all other Kell antigens and abnormal red cells (acanthocytes) morphology which has been associated with X-linked chronic granulomatous disease, which is a rare disorder affecting males.
This condition is also associated with the following:
1. Chronic but well compensated hemolytic anemia
2. Reticulocytosis and acantocytosis
3. Muscular dystrophy
4. Common among males suffering CGD
a)
McLeod Phenotype
b)
K null Phenotype
19.
Kell
a)
Kell 1
b)
Kell 2
c)
Kell 3
d)
Kell 4
20.
K
a)
Kell 1
b)
Kell 2
c)
Kell 3
d)
Kell 4
21.
k
a)
Kell 1
b)
Kell 2
c)
Kell 3
d)
Kell 4
22.
Cellano
a)
Kell 1
b)
Kell 2
c)
Kell 3
d)
Kell 4
23.
Kpa
a)
Kell 1
b)
Kell 2
c)
Kell 3
d)
Kell 4
24.
Penney
a)
Kell 1
b)
Kell 2
c)
Kell 3
d)
Kell 4
25.
Kpb
a)
Kell 1
b)
Kell 2
c)
Kell 3
d)
Kell 4
26.
Rautenberg
a)
Kell 1
b)
Kell 2
c)
Kell 3
d)
Kell 4
27.
K1
a)
Kell
b)
Cellano
c)
Class
d)
Williams
28.
K
a)
Kell
b)
Cellano
c)
Class
d)
Williams
29.
k
a)
Kell
b)
Cellano
c)
Class
d)
Williams
30.
Kell 2
a)
Kell
b)
Cellano
c)
Class
d)
Williams
31.
KI
a)
Kell
b)
Cellano
c)
Class
d)
Williams
32.
Kw
a)
Kell
b)
Cellano
c)
Class
d)
Williams
33.
Jsa
a)
Kell 6
b)
Kell 7
c)
KI
d)
Kw
e)
Ku
34.
Suffer
a)
Kell 6
b)
Kell 7
c)
KI
d)
Kw
e)
Ku
35.
Jsb
a)
Kell 6
b)
Kell 7
c)
KI
d)
Kw
e)
Ku
36.
Matthews
a)
Kell 6
b)
Kell 7
c)
KI
d)
Kw
e)
Ku
37.
Williams
a)
Kell 6
b)
Kell 7
c)
KI
d)
Kw
e)
Ku
38.
Class
a)
Kell 6
b)
Kell 7
c)
KI
d)
Kw
e)
Ku
39.
Peltz
a)
Kell 6
b)
Kell 7
c)
KI
d)
Kw
e)
Ku
40.
Kell 4
a)
Rautenberg
b)
Williams
c)
Jsa. Suffer
d)
Jsb. Matthews
e)
Peltz
41.
Kpb
a)
Rautenberg
b)
Williams
c)
Jsa. Suffer
d)
Jsb. Matthews
e)
Peltz
42.
Kell 7
a)
Rautenberg
b)
Williams
c)
Jsa. Suffer
d)
Jsb. Matthews
e)
Peltz
43.
Kell 6
a)
Rautenberg
b)
Williams
c)
Jsa. Suffer
d)
Jsb. Matthews
e)
Peltz
44.
Ku
a)
Rautenberg
b)
Williams
c)
Jsa. Suffer
d)
Jsb. Matthews
e)
Peltz
45.
Which of the following has PRESENT Kx antigen?
a)
K null
b)
McLeod
46.
Which of the following has LACKS the autosomal Kell antigen?
a)
K null
b)
McLeod
47.
Which of the following DON'T HAVE any red cell abnormality?
a)
K null
b)
McLeod
48.
Which of the following HAS red cell abnormality?
a)
K null
b)
McLeod
49.
Which of the following HAS DECREASED EXPRESSION of autosomal Kell antigen?
a)
K null
b)
McLeod
50.
Which of the following lacks Kx antigen?
a)
K null
b)
McLeod
51.
Does K Null have red cell abnormality?
a)
Yes
b)
No
52.
Does McLeod have red cell abnormality?
a)
Yes
b)
No
53.
What is the amount of autosomal Kell antigen found in K null?
a)
Decreased expression
b)
Lacks / none
54.
What is the amount of autosomal Kell antigen found in McLeod?
a)
Decreased expression
b)
Lacks / none
55.
What is the status of Kx antigen found in K null?
a)
Present
b)
Lacks / none
56.
What is the status of Kx antigen found in McLeod?
a)
Present
b)
Lacks / none
57.
Which of the kell phenotypes is rare in whites and 19% only in blacks?
a)
Js (a+ b+)
b)
Kp (a+ b+)
c)
K- k+
d)
Js (a+ b-)
58.
Which of the kell phenotypes is rare in blacks and only 2.3% in whites?
a)
Js (a+ b+)
b)
Kp (a+ b+)
c)
K- k+
d)
Js (a+ b-)
59.
Which of the following Kidd antigens has been detected on fetal RBCs as early as 11 weeks?
a)
Jka
b)
Jkb
60.
Which of the following Kidd antigens has been detected on fetal RBCs AT 7 WEEKS?
a)
Jka
b)
Jkb
61.
more resistant to lysis in the presence of 2M urea; normall kidd phenotypes swell and lyse rapidly on exposure to 2M urea.
a)
JK(a-b-)
b)
Jk(a+b-)
c)
Jk(a+b+)
62.
most abundant although rare among Polynesians and has all been identified in Filipinos, Indonesians, and HCinese
a)
JK(a-b-)
b)
Jk(a+b-)
c)
Jk(a+b+)
63.
Black
a)
JK(a-b-)
b)
Jk(a+b-)
c)
Jk(a+b+)
64.
Whites
a)
JK(a-b-)
b)
Jk(a+b-)
c)
Jk(a+b+)
65.
Are kidd antibodies, Anti-Jka and Anti-Jkb clinically significant?
a)
Yes
b)
No
66.
discovered in the seurm of px with lupus erythematosus
a)
Kidd
b)
Lutheran
67.
Antigens of this blood group do not reach adult level until 25
a)
Kidd
b)
Lutheran
68.
Lutheran antigens
a)
Well-developed at birth
b)
Poorly developed at birth
69.
may be Iga, IgG, or IgM (optimal tem is at RT)
a)
anti-Lua
b)
anti-Lub
70.
Optimal in vitro agglutination reactions are observed at room temperature
a)
anti-Lua
b)
anti-Lub
71.
Rare, most are IgG (clinically significant)
a)
anti-Lua
b)
anti-Lub
72.
Made in response to pregnancy or transfusion
a)
anti-Lua
b)
anti-Lub
73.
Implicated with shortened suvival of transfused cells and post transfusion jaundice
a)
anti-Lua
b)
anti-Lub
100 %
