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Anaemia in ICU

Total questions: 15

Worksheet time: 8mins

Name
Class
Date
1.

Which hemoglobin threshold defines anemia in women under WHO criteria?

a)

Below 11 g/dL in women

b)

Below 12 g/dL in women

c)

Below 13 g/dL in women

d)

Below 14 g/dL in women

2.

which nutrients, when deficient, most impair red blood cell production?

a)

Iron stores for heme synthesis

b)

Vitamin B12 for DNA replication

c)

Folate for thymidylate synthesis

d)

Vitamin C for collagen crosslinks

3.

A patient with chronic kidney disease develops anemia. What is the most likely direct pathophysiologic contributor?

a)

Absolute erythropoietin deficiency due to renal dysfunction

b)

Iron loss from occult gastrointestinal bleeding

c)

Autoimmune hemolysis triggered by antibiotics

d)

Coagulation abnormalities causing microthrombi

4.

Which nutritional deficiency most directly causes megaloblastic anemia?

a)

Low folate levels

b)

Low iron levels

c)

Low erythropoietin levels

d)

Low copper levels

5.

Mean corpuscular volume (MCV) of 72 fL would classify the anemia as which type?

a)

Microcytic anemia present

b)

Normocytic anemia present

c)

Macrocytic anemia present

d)

Dimorphic anemia present

6.

Which two conditions are most linked to sickle-shaped erythrocytes on smear?

a)

Sickle cell disease

b)

Sickle–thalassemia syndromes

c)

Warm autoimmune hemolysis

d)

Liver disease

7.

Which scenario best represents anemia due to red blood cell loss rather than production or destruction?

a)

Chronic kidney disease reducing erythropoietin

b)

Acute gastrointestinal bleeding causing hemorrhage

c)

Autoimmune hemolysis with elevated LDH

d)

Methotrexate suppressing bone marrow

e)

Strict vegan diet lacking vitamin B12

8.

Select all mechanisms that directly lead to decreased red blood cell production.

a)

Inflammatory cytokines suppressing marrow

b)

Iron deficiency impairing hemoglobin

c)

Renal dysfunction lowering erythropoietin

d)

Hereditary spherocytosis causing hemolysis

9.

Which finding most strongly suggests increased red blood cell destruction (hemolysis)?

a)

Low reticulocyte count with marrow suppression

b)

High reticulocyte count with jaundice

c)

Normal EPO with occult blood loss

d)

Low iron with microcytosis

e)

Low folate with hypersegmented neutrophils

10.

What is the primary mechanism of action of erythropoietin in the treatment of anemia?

a)

Enhances platelet aggregation

b)

Increases red blood cell production in the bone marrow

c)

Inhibits red blood cell destruction in the spleen

d)

Stimulates iron absorption in the gut

11.

Which laboratory finding is most indicative of iron deficiency anemia?

a)

Increased ferritin levels

b)

Low serum iron and high total iron-binding capacity

c)

Elevated bilirubin levels

d)

Normal reticulocyte count

12.

In which condition would you expect to find a high level of haptoglobin?

a)

Hemolytic anemia

b)

Acute liver failure

c)

Chronic inflammation

d)

Iron overload syndromes

13.

What is the most common cause of microcytic anemia?

a)

Folate deficiency

b)

Chronic disease

c)

Vitamin B12 deficiency

d)

Iron deficiency

14.

In which condition would you expect to see a high mean corpuscular hemoglobin concentration (MCHC)?

a)

Hereditary spherocytosis

b)

Chronic kidney disease

c)

Iron deficiency anemia

d)

Thalassemia

15.

Identify type of anaemia

a)

Hereditary sperocytosis

b)

Sickle cell anaemia

c)

Macrocytic anaemia

d)

microcytic hypochromic anaemia