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WorksheetsBlood Banking MCQs
Total questions: 100
Worksheet time: 50mins
What is the universal donor blood group?
A+
B-
AB+
O-
Which blood group is called the universal recipient?
A+
AB+
B-
O+
Which antigen is present on the surface of red blood cells in the A blood group?
B antigen
A antigen
Rh antigen
H antigen
The Rh factor is also known as:
Rhesus factor
ABO antigen
Kell antigen
Duffy antigen
Which test is used to determine the ABO blood group?
Coombs test
Crossmatch test
Agglutination test
ELISA test
What is the main purpose of crossmatching before transfusion?
To identify infections
To check compatibility between donor and recipient
To count red blood cells
To measure hemoglobin
Which anticoagulant is commonly used in blood collection bags?
EDTA
Heparin
Citrate phosphate dextrose (CPD)
Sodium fluoride
What is the maximum storage time for red blood cells at 4°C?
7 days
21 days
35-42 days
3 months
Which of the following is a blood component?
Platelets
Plasma
Red blood cells
All of the above
Which blood component is primarily responsible for clotting?
Red blood cells
Platelets
Plasma
White blood cells
Which infectious agent is screened for in blood donations?
HIV
Hepatitis B
Syphilis
All of the above
What does a direct antiglobulin test (DAT) detect?
Free antibodies in serum
Antibodies bound to red cells
Blood group antigens
Bacterial contamination
Which blood group system includes Kell, Duffy, and Kidd antigens?
ABO system
Rh system
What is the acceptable age range for blood donors?
16-60 years
18-65 years
21-70 years
12-50 years
What is the minimum hemoglobin level for a blood donor?
9 g/dl
10 g/dl
12.5 g/dl
15 g/dl
What are packed red blood cells?
Whole blood without plasma
Platelets concentrate
Plasma only
Blood with added anticoagulant
Which condition requires transfusion of fresh frozen plasma (FFP)?
Anemia
Coagulation factor deficiencies
Thrombocytopenia
Leukemia
What temperature is fresh frozen plasma stored at?
-20°C or below
4°C
Room temperature
37°C
What is the shelf life of platelet concentrates stored at room temperature?
1 day
3-5 days
7 days
14 days
Which test confirms the absence of irregular antibodies in blood?
Direct Coombs test
Indirect Coombs test
Blood culture
ELISA
Which is a symptom of an acute hemolytic transfusion reaction?
Fever and chills
Rash and itching
Weight gain
Increased appetite
What is the main reason for deferral of a blood donor?
Allergies
Recent infection or illness
Mild headache
Excessive sleep
Which of the following is not a blood component?
Serum
Plasma
Red blood cells
Platelets
What does plasma contain?
Only water
Red blood cells
Proteins, hormones, electrolytes
Platelets only
Which blood group has neither A nor B antigen?
A
B
AB
O
Which antigen presence defines Rh positive?
D antigen
B antigen
What is autologous blood donation?
Donating blood to family
Donating one's own blood for future use
Donating to strangers
Blood from blood banks
What is the typical volume of blood collected during donation?
100 ml
250 ml
450-500 ml
1 liter
What is blood grouping based on?
Shape of red cells
Antigens present on red cell surface
Size of white cells
Color of plasma
What is the Rh incompatibility concern during pregnancy?
Severe maternal bleeding
Hemolytic disease of the newborn
No concern
Fetal malnutrition
Which anticoagulant is preferred in blood collection?
EDTA
Heparin sodium
CPDA-1
Sodium citrate
What is the main purpose of blood irradiation?
To kill bacteria
To prevent graft-versus-host disease
To change blood group
To sterilize plasma
What does leukoreduced blood mean?
Blood with reduced red cells
Blood with reduced white cells
Blood with less platelets
Blood without plasma
How long can whole blood be safely stored?
24 hours
1 week
Up to 35-42 days depending on preservative
6 months
What is the major cause of transfusion-related acute lung injury (TRALI)?
Allergic reaction
Antibodies in donor plasma
Bacterial contamination
Iron overload
Which condition may require platelet transfusion?
Anemia
Thrombocytopenia
Leukocytosis
Polycythemia
What is blood group “Bombay”?
A rare blood group lacking H antigen
A variant of group B
Another term for AB group
A synthetic blood type
Which test detects unexpected antibodies in the recipient's serum?
Compatibility testing
Direct Coombs test
Antibody screening
Blood typing
How are blood units screened for infections?
Visual inspection
Serological and molecular tests
What is the shelf life of cryoprecipitate?
24 hours
1 week
1 year at -18°C
5 years
Who is eligible to donate blood?
Anyone above 18 years with good health
Patients recovering from infection
Children below 16 years
Pregnant women
What is the minimum interval between two whole blood donations?
7 days
1 month
3 months
6 months
Which blood component is rich in clotting factors?
Platelets
Packed red cells
Fresh frozen plasma (FFP)
Whole blood
Which antigen is not part of the ABO system?
A
B
Rh
AB
What does a blood transfusion reaction imply?
Normal procedure
Adverse response to transfusion
Successful transfusion
Delay in transfusion
What is hemolysis?
Blood clotting
Destruction of red blood cells
Formation of white blood cells
Platelet aggregation
How soon should red blood cells be transfused once removed from cold storage?
Immediately or within 4 hours
After 24 hours
Within 12 hours
After 1 week
Which factor can cause bacterial contamination in blood units?
Inadequate donor screening
Poor storage
Long transfusion duration
All of the above
What is the function of a blood bank?
To collect, store, and distribute blood and blood components
To sell blood
To manufacture synthetic blood
To perform surgeries
Which of these is NOT a blood group system?
ABO
RH
HLA
DNA
What blood group is called the universal donor?
A
B
AB
O
Which blood type has both A and B antigens on the red blood cells?
A
B
AB
O
What antibodies are present in the plasma of a person with blood type A?
Anti-A
Anti-B
Both Anti-A and Anti-B
No antibodies
Blood type O lacks which antigens?
A only
B only
A and B
Rh
What determines the Rh positive or negative status?
Presence of A antigen
Presence of B antigen
Presence of D antigen
Presence of AB antigen
A person with blood type B can receive blood from which group(s)?
B and O
A and O
AB and A
Only B
What is the main cause of hemolytic disease of the newborn?
ABO incompatibility
Rh incompatibility
Which blood group is known as the universal recipient?
A
B
AB
O
Blood plasma contains which of the following antibodies?
Antibodies against own antigens
Antibodies against foreign antigens
No antibodies
Only Rh antibodies
What happens if incompatible blood types are mixed during transfusion?
No reaction
Agglutination and hemolysis
Increased oxygen delivery
No effect
What does ABO blood grouping test detect?
Antigens on red blood cells
Antibodies in plasma
Platelet count
White blood cell count
What does Rh blood typing detect?
A and B antigens
D antigen (Rh factor)
Plasma proteins
Clotting factors
Which blood type is characterized by the presence of anti-A and anti-B antibodies?
A
B
AB
Which blood type has no anti-A or anti-B antibodies in the plasma?
A
B
AB
O
Which blood type can donate to all other types?
A
B
AB
O
What blood type can receive blood from any other blood group?
A
B
AB
O
Which antigen is present in Rh positive blood?
A
B
D
AB
Can Rh negative individuals receive Rh positive blood?
Yes
No
Sometimes
Only in emergencies
What method is commonly used for blood typing?
PCR
Agglutination test
Electrophoresis
ELISA
What is the compatibility of blood between a donor with blood group A and a recipient with blood group B?
Compatible
Incompatible
Compatible if Rh negative
Incompatible if Rh positive
Blood type AB has which antibodies in plasma?
Anti-A
Anti-B
Both anti-A and anti-B
No antibodies
What is the primary function of red blood cell antigens?
Oxygen transport
Blood clotting
Blood group identification
White blood cell recognition
What is the risk of transfusing the wrong blood type?
Increased oxygenation
Hemolytic transfusion reaction
Immunosuppression
No risk
What does a positive crossmatch indicate?
Compatible blood
Incompatible blood
No antigens present
Immune deficiency
What blood group does a person with anti-B antibodies have?
A
B
AB
O
Which blood group has anti-A antibodies only?
(a)
Which blood group is known as the universal donor?
A
B
AB
O
How is blood type inherited?
Mitochondrial inheritance
Autosomal recessive
Autosomal dominant
Multiple alleles inheritance
How many alleles determine ABO blood group?
One
Two
Three
Four
What blood group antigen is missing in blood type O?
A antigen
B antigen
Both A and B antigen
Rh antigen
What is the antigen profile of blood type B?
A antigen
B antigen
Both A and B antigen
No antigens
Which antibodies are present in blood type AB plasma?
Anti-A antibodies
Anti-B antibodies
Both anti-A and anti-B antibodies
No antibodies
What blood group can donate to type AB?
O only
A only
B only
What does Rh negative mean?
Presence of D antigen
Absence of D antigen
Presence of A antigen
Presence of B antigen
What blood types can a person with A+ receive?
A+, A-, O+, O-
B+, AB+, O+, O-
All blood types
O only
What blood type is called the universal recipient?
A
B
AB
O
What type of antibodies are naturally present for ABO groups?
IgM
IgG
IgE
IgA
Which cell type carries blood group antigens?
White blood cells
Platelets
Red blood cells
Plasma cells
Which blood group is the most common worldwide?
A
B
AB
O
How are blood types tested?
Using antigen and antibody reactions
DNA sequencing
Microscopy
Colorimetric tests
Why is it important to know blood type before transfusion?
To match donor-recipient compatibility
To choose correct infusion rate
To detect infection
To check hemoglobin levels
What happens during an agglutination reaction?
Red blood cells clump
Red blood cells dissolve
White blood cells increase
Platelets activate
Which blood group is rarest?
A
B
AB
O
What blood group is characterized by absence of A, B, and Rh antigens?
A-
B-
O-
AB-
Who discovered the ABO blood group system?
Landsteiner
Watson
Crick
Mendel
What is the function of antibodies in blood typing?
Enhances clotting
Recognizes foreign antigens
How often should blood typing be confirmed in patients needing transfusion?
Once in a lifetime
Before every transfusion
Every 5 years
Only once per hospitalization
What is the principle behind blood typing tests?
Enzyme reaction
Antigen-antibody interaction
DNA hybridization
pH change
Which blood type has anti-A and anti-B antibodies?
AB
O
A
B
What is Rh incompatibility?
Mismatch of ABO antigens
Mismatch in Rh factor causing immune reaction
Blood clot formation
Low red blood cells
