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Pengantar Biokimia Klinik dan Konsep Metabolisme

Total questions: 10

Worksheet time: 5mins

Name
Class
Date
1.

Which statement best defines clinical biochemistry in a healthcare setting?

a)

Study of biochemical body components for patient care

b)

Study of cell genetics for evolutionary relationships

c)

Study of microbial ecology in natural ecosystems

d)

Study of physical chemistry of inorganic crystals

2.

Which pairing correctly matches the metabolic category with its primary energy relationship?

a)

Catabolism releases energy as ATP

b)

Anabolism releases energy as ATP

c)

Catabolism requires energy as ATP

d)

Anabolism neither uses nor releases ATP

3.

During catabolism, which sequence of stages is most accurate for macromolecules?

a)

Macromolecule separation, monomer oxidation, ATP production

b)

ATP production, monomer oxidation, macromolecule separation

c)

Monomer synthesis, macromolecule fusion, ATP consumption

d)

Macromolecule oxidation, monomer formation, ATP neutralization

4.

Which statement best describes glycolysis in cellular metabolism?

a)

Breakdown of glucose to pyruvate in cytosol

b)

Oxidation of fatty acids to acetyl‑CoA in matrix

c)

Removal of amino groups from amino acids in liver

d)

Conversion of pyruvate to glucose in mitochondria

5.

During beta‑oxidation, the immediate product that feeds the citric acid cycle is produced along with which reduced cofactors?

a)

Acetyl‑CoA with FADH2 and NADH

b)

Acetyl‑CoA with ATP and GTP

c)

Pyruvate with FAD and NAD+

d)

Citrate with NADPH and FADH2

6.

Deamination primarily yields which pair of products before carbon enters central metabolism?

a)

Ammonia and a carbon skeleton

b)

Lactate and acetyl‑CoA

c)

Carbon dioxide and water

d)

Alanine and oxaloacetate

7.

Which statement best describes protein synthesis in cells?

a)

Amino acids join via peptide bonds on ribosomes

b)

Glucose forms from lactate in kidney mitochondria

c)

Fatty acids are oxidized to acetyl‑CoA for ATP

d)

Triglycerides hydrolyze into glycerol and fatty acids

8.

Which factor best explains phenylketonuria (PKU) due to lack of phenylalanine hydroxylase?

a)

Genetic mutation affecting metabolic enzymes

b)

Nutrient excess altering enzyme cofactors

c)

Chronic liver disease reducing detox pathways

d)

Stress-related lifestyle decreasing activity

9.

A patient with heavy metal exposure develops disrupted enzyme function. Which factor is most likely responsible?

a)

Environmental toxin exposure affecting metabolism

b)

Hormonal surge increasing glucose regulation

c)

Genetic polymorphism improving enzyme stability

d)

Balanced diet enhancing micronutrient availability

10.

Which biochemical defect best explains hyperglycemia in Diabetes Mellitus?

a)

Impaired insulin production or action

b)

Excessive thyroid hormone secretion

c)

Defective tyrosinase in melanocytes

d)

Overactive phenylalanine transaminase