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Antibiotic Selection Quiz

Total questions: 10

Worksheet time: 5mins

Name
Class
Date
1.

A 32-year-old man has a Streptococcal throat infection. The antibiotic must be highly active against Gram-positive bacteria but is destroyed by gastric acid, therefore given by injection. Which antibiotic is most suitable?

a)

Penicillin V

b)

Penicillin G

c)

Ampicillin

d)

Methicillin

2.

A 12-year-old child requires oral antibiotic therapy for Streptococcal infection. The drug should have same spectrum as Penicillin G but more acid-resistant. Which antibiotic fits this description?

a)

Carbenicillin

b)

Penicillin V

c)

Ticarcillin

d)

Cefazolin

3.

A 45-year-old patient has a mixed infection of Gram-positive and Gram-negative bacteria. The physician prescribes a broad-spectrum, acid-stable penicillin. Which drug is appropriate?

a)

Ampicillin

b)

Methicillin

c)

Vancomycin

d)

Cefoxitin

4.

A hospitalized patient has Pseudomonas aeruginosa infection. The antibiotic selected is a penicillin that is highly active against Pseudomonas. Which antibiotic should be administered?

a)

Ampicillin

b)

Ticarcillin

c)

Methicillin

d)

Penicillin V

5.

A patient presents with Staphylococcus aureus infection that produces β-lactamase (penicillinase). Which antibiotic would be most effective?

a)

Penicillin G

b)

Ceftriaxone

c)

Methicillin

d)

Ampicillin

6.

Which first-generation cephalosporin is most effective primarily against Gram-positive bacteria?

a)

Cefoperazone

b)

Cephalothin

c)

Cefepime

d)

Cefoxitin

7.

A physician treats Gram-negative abdominal infection involving anaerobes. The drug belongs to second-generation cephalosporins. Which drug is indicated?

a)

Cefoxitin

b)

Ceftriaxone

c)

Cefazolin

d)

Cefepime

8.

A young patient with meningitis needs a drug that crosses the blood–brain barrier and is third-generation cephalosporin. Which antibiotic is the best choice?

a)

Cefoperazone

b)

Ceftriaxone

c)

Penicillin V

d)

Methicillin

9.

A patient with Pseudomonas septicemia requires a fourth-generation cephalosporin with excellent broad Gram-positive and Gram-negative coverage. Which drug is preferred?

a)

Cefepime

b)

Cefoxitin

c)

Ampicillin

d)

Carbenicillin

10.

A critically ill patient has a multidrug-resistant Enterococcus and Staphylococcus infection. The doctor selects the last-resort drug that binds to D-Ala-D-Ala and blocks peptidoglycan cross-linking. Which antibiotic is this?

a)

Streptomycin

b)

Vancomycin

c)

Cefazolin

d)

Penicillin G