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MCQs: Approach to Proteinuria (MBBS Level)

Total questions: 10

Worksheet time: 3mins

Name
Class
Date
1.

A 12-year-old asymptomatic boy has 2+ protein on random urine dipstick but trace protein on early morning sample. Most likely diagnosis is:

a)

Minimal change disease

b)

Acute glomerulonephritis

c)

Orthostatic proteinuria

d)

Tubular proteinuria

2.

Normal protein excretion in children is defined as:

a)

<150 mg/day

b)

<100 mg/m^2/day

c)

<300 mg/m^2/day

d)

<40 mg/m^2/hour

3.

Nephrotic-range proteinuria in children is best defined by:

a)

Urine dipstick 2+

b)

Protein >1 g/day

c)

Urine protein–creatinine ratio >2

d)

Serum albumin <3 g/dL

4.

Predominant site of injury in heavy glomerular proteinuria is:

a)

Endothelium

b)

Basement membrane

c)

Podocyte

d)

Mesangium

5.

Major normally excreted urinary protein is:

a)

Albumin

b)

IgG

c)

Tamm-Horsfall protein

d)

Beta-2 microglobulin

6.

Child with edema, 4+ proteinuria, low albumin and bland urine sediment most likely has:

a)

PSGN

b)

Minimal change disease

c)

IgA nephropathy

d)

HUS

7.

Feature distinguishing glomerular from tubular proteinuria:

a)

Edema

b)

Degree of proteinuria

c)

Albumin as main urinary protein

d)

Hypertension

8.

Transient proteinuria is NOT associated with:

a)

Fever

b)

Exercise

c)

Dehydration

d)

Persistent hypertension

9.

Gold standard test for quantifying proteinuria:

a)

Dipstick

b)

Spot PCR

c)

Microalbuminuria

d)

24-hour urine protein

10.

Absence of proteinuria in first morning urine for 3 days confirms:

a)

Transient proteinuria

b)

Nephrotic syndrome

c)

Orthostatic proteinuria

d)

Tubular proteinuria