Free Printable Immunology Quiz

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Worksheets

Immunology Quiz

Total questions: 22

Worksheet time: 11mins

Name

Class

Date

1.

Superantigens activate T cells by binding to

a)

MHC I only

b)

Processed peptide antigen

c)

TCR Vβ region and MHC II outside peptide groove

d)

CD8 receptor

2.

Example of a bacterial superantigen is

a)

Exotoxin A

b)

TSST-1

c)

Endotoxin

d)

Enterotoxin B

3.

Main effect of superantigens is

a)

Specific immune response

b)

Massive cytokine release

c)

Immunosuppression

d)

Complement activation

4.

Immunoglobulins are produced by

a)

Macrophages

b)

T lymphocytes

c)

Plasma cells

d)

Neutrophils

5.

Which immunoglobulin crosses placenta?

a)

IgA

b)

IgE

c)

IgG

d)

IgM

6.

IgE is mainly involved in

a)

Complement activation

b)

Opsonization

c)

Type I hypersensitivity

d)

Mucosal immunity

7.

Secretory IgA is mainly found in

a)

Serum

b)

CSF

c)

Colostrum and secretions

d)

Placenta

8.

IgM is the first antibody produced in

a)

Secondary immune response

b)

Allergic reactions

c)

Primary immune response

d)

Autoimmune diseases

9.

Pentameric structure is characteristic of

a)

IgG

b)

IgA

c)

IgE

d)

IgM

10.

Monoclonal antibodies are produced by

a)

Single plasma cell clone

b)

Multiple B cell clones

c)

T cells only

d)

Hybridoma cells derived from fusion

11.

Major application of monoclonal antibodies is

a)

Vaccine production

b)

Diagnosis and targeted therapy

c)

Antibiotic resistance testing

d)

Complement fixation

12.

Agglutination reactions involve

a)

Soluble antigen–antibody reaction

b)

Particulate antigen–antibody reaction

c)

Cell-mediated immunity

d)

Complement lysis

13.

Example of agglutination test is

a)

ELISA

b)

Widal test

c)

Western blot

d)

Neutralization test

14.

Agglutination reactions are useful for

a)

Measuring hormones

b)

Detecting antibodies or antigens

c)

Bacterial culture

d)

Drug sensitivity testing

15.

Complement system consists mainly of

a)

Immunoglobulins only

b)

Enzymes and plasma proteins

c)

Cell surface receptors

d)

Cytokines

16.

Classical complement pathway is activated by

a)

Endotoxin

b)

Antigen–antibody complex

c)

Microbial surfaces

d)

Properdin

17.

First component activated in classical pathway is

a)

C3

b)

C5

c)

C1q

d)

C9

18.

Alternative complement pathway is activated by

a)

IgG and IgM

b)

Antigen–antibody complexes

c)

Microbial cell surfaces

d)

C1 complex

19.

C3 convertase of alternative pathway is

a)

C4b2a

b)

C3bBb

c)

C5b678

d)

C1qrs

20.

Deficiency of C5–C9 predisposes to infections with

a)

Staphylococcus

b)

Streptococcus

c)

N. meningitidis

d)

E. coli

21.

B cells are primarily responsible for

a)

Cell-mediated immunity

b)

Antibody production

c)

Phagocytosis

d)

Complement activation

22.

T helper cells are identified by

a)

CD8 marker

b)

CD4 marker

c)

CD19 marker

d)

CD21 marker

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