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PHA final practice 2

Total questions: 124

Worksheet time: 1hrs 2mins

Name
Class
Date
1.

Which of the following is the primary action of a Beta-2 adrenergic agonist?

a)

Vasoconstriction

b)

Bronchodilation

c)

Decreased heart rate

d)

Bladder contraction

2.

True or False: The "Generic Name" of a drug is the proprietary name owned by a specific manufacturer.

a)

True

b)

False

3.

A patient is prescribed Epinephrine for anaphylaxis. The nurse knows this drug acts on which receptors? (Select All That Apply)

a)

Alpha-1

b)

Alpha-2

c)

Beta-1

d)

Beta-2

4.

Which laboratory value is most critical to monitor for a patient taking Valproic Acid?

a)

Serum Glucose

b)

Liver Enzymes (ALT/AST)

c)

Creatinine Clearance

d)

White Blood Cell Count

5.

A patient is taking Phenytoin (Dilantin). Which statement by the patient indicates a need for further teaching?

a)

I will use a soft toothbrush to prevent gum bleeding.

b)

I can stop taking this medication once I haven't had a seizure for a month.

c)

I should avoid drinking alcohol while on this medication.

d)

I need to have my blood levels checked regularly.

6.

What is the drug of choice for treating Status Epilepticus initially?

a)

Oral Valproic acid

b)

IV Diazepam or Lorazepam

c)

IM Phenytoin

d)

Subcutaneous Epinephrine

7.

True or False: Tolerance occurs when a patient requires a higher dosage of a drug to achieve the same therapeutic effect.

a)

True

b)

False

8.

Which of the following are common adverse effects of Anticholinergic drugs? (Select All That Apply)

a)

Urinary retention

b)

Excessive salivation

c)

Blurred vision

d)

Constipation

e)

Diarrhea

9.

The nurse is teaching a patient about Levodopa/Carbidopa. Which side effect should the nurse emphasize?

a)

Hypertension

b)

Orthostatic hypotension

c)

Excessive hair growth

d)

Weight gain

10.

A patient on Lithium therapy reports a metallic taste, hand tremors, and diarrhea. The nurse suspects:

a)

Therapeutic response

b)

Lithium toxicity

c)

Allergic reaction

d)

Normal side effects

11.

Which drug is used as the "rescue" inhaler for acute bronchospasm?

a)

Salmeterol

b)

Albuterol

c)

Tiotropium

d)

Montelukast

12.

True or False: Vancomycin should be administered rapidly via IV push to prevent infection spread.

a)

True

b)

False

13.

Which adverse effect is specifically associated with the "Red Man Syndrome"?

a)

Penicillin

b)

Vancomycin

c)

Gentamicin

d)

Tetracycline

14.

A patient is taking an MAO Inhibitor (MAOI) for depression. Which food should they avoid?

a)

Apples

b)

Aged cheddar cheese

c)

Grilled chicken

d)

Fresh carrots

15.

What is the primary concern when a patient is taking both a Benzodiazepine and Alcohol?

a)

Increased heart rate

b)

Severe CNS depression/Respiratory depression

c)

Hypertensive crisis

d)

Liver failure

16.

True or False: Pharmacokinetics is the study of what the drug does to the body.

a)

True

b)

False

17.

Which drug class is often used to treat the "positive" symptoms of Schizophrenia?

a)

Mood stabilizers

b)

Antipsychotics

c)

Stimulants

d)

Anticholinergics

18.

A patient is receiving an Opioid analgesic. What is the priority nursing assessment?

a)

Temperature

b)

Respiratory rate

c)

Bowel sounds

d)

Blood glucose

19.

Which medication is the antidote for an Acetaminophen overdose?

a)

Naloxone

b)

Vitamin K

c)

Acetylcysteine

d)

Flumazenil

20.

True or False: NSAIDs like Ibuprofen can cause gastric ulcers by inhibiting the COX-1 enzyme.

a)

True

b)

False

21.

The nurse provides teaching for a patient starting Methylphenidate (Ritalin). Which instruction is correct?

a)

Take the medication right before bed.

b)

Avoid caffeine while taking this drug.

c)

You can stop the drug abruptly if you feel better.

d)

Expect to gain weight while on this medication.

22.

Which of the following are characteristic symptoms of Parkinson’s Disease? (Select All That Apply)

a)

Bradykinesia

b)

Muscle rigidity

c)

Pill-rolling tremors

d)

Excessive dopamine levels

23.

The Half-life of a drug is defined as:

a)

The time it takes for the drug to reach peak action.

b)

The time it takes for half of the drug to be eliminated from the body.

c)

The duration of the therapeutic effect.

d)

The time until the first dose is metabolized.

24.

A patient is prescribed Atropine. This drug is classified as a:

a)

Adrenergic Agonist

b)

Cholinergic Agonist

c)

Anticholinergic

d)

Beta-blocker

25.

True or False: Epinephrine is non-selective, meaning it stimulates multiple types of adrenergic receptors.

a)

True

b)

False

26.

Which of the following is a "Black Box Warning" for many antidepressants?

a)

Risk of weight loss

b)

Increased risk of suicidal ideation in children/young adults

c)

Risk of permanent hearing loss

d)

Risk of dental cavities

27.

A patient is allergic to Penicillin. The nurse should be cautious when administering which other class of antibiotics due to cross-sensitivity?

a)

Tetracyclines

b)

Cephalosporins

c)

Sulfonamides

d)

Aminoglycosides

28.

What is the mechanism of action for Naloxone (Narcan)?

a)

It stimulates opioid receptors.

b)

It blocks opioid receptors (Antagonist).

c)

It increases serotonin levels.

d)

It slows down metabolism.

29.

True or False: Schedule I controlled substances have a high potential for abuse and no accepted medical use.

a)

True

b)

False

30.

Which organ is primarily responsible for drug metabolism?

a)

Kidneys

b)

Liver

c)

Lungs

d)

Small intestine

31.

A patient taking a first-generation antihistamine (like Diphenhydramine) should be warned about:

a)

Hypertension

b)

Drowsiness and sedation

c)

Increased appetite

d)

Diarrhea

32.

Which of the following are nursing interventions for a patient on a stimulant? (Select All That Apply)

a)

Monitor height and weight in children

b)

Monitor blood pressure

c)

Encourage intake of decaffeinated beverages

d)

Administer dose at 9:00 PM

33.

The Therapeutic Index (TI) measures:

a)

How fast a drug works

b)

The safety margin of a drug (ratio of toxic dose to therapeutic dose)

c)

The price of the medication

d)

The frequency of dosing

34.

True or False: Agonists are drugs that bind to a receptor and block a response.

a)

True

b)

False

35.

Which of the following describes "Superinfection"?

a)

An infection that is resistant to all known drugs

b)

A secondary infection that occurs when normal flora is destroyed by antibiotics

c)

A viral infection that turns into a bacterial infection

d)

An infection that requires three or more antibiotics

36.

A patient is prescribed Albuterol and a Beclomethasone (steroid) inhaler. How should they be used?

a)

Steroid first, then Albuterol

b)

Albuterol first, then wait 5 minutes, then Steroid

c)

Mix them together in the nebulizer

d)

Use Albuterol only at night

37.

What is a major side effect of loop diuretics (like Furosemide)?

a)

Hyperkalemia

b)

Hypokalemia

c)

Hypertension

d)

Weight gain

38.

True or False: Aspirin should not be given to children with viral symptoms due to the risk of Reye's syndrome.

a)

True

b)

False

39.

Which drug is used to treat a dry, non-productive cough?

a)

Expectorant

b)

Antitussive

c)

Bronchodilator

d)

Decongestant

40.

A patient is taking Warfarin (Coumadin). The nurse should teach the patient to maintain a consistent intake of:

a)

Vitamin C

b)

Vitamin K (green leafy vegetables)

c)

Carbohydrates

d)

Red meat

41.

Which medication is considered a mood stabilizer?

a)

Sertraline

b)

Lithium

c)

Alprazolam

d)

Haloperidol

42.

True or False: First-pass effect refers to the metabolism of a drug by the liver before it reaches systemic circulation.

a)

True

b)

False

43.

A patient is taking a beta-blocker (e.g., Atenolol). Which vital sign is most important to check before administration?

a)

Temperature

b)

Heart rate

c)

Oxygen saturation

d)

Respiratory rate

44.

Symptoms of "Salicylism" (aspirin toxicity) include: (Select All That Apply)

a)

Tinnitus (ringing in ears)

b)

Dizziness

c)

Bradycardia

d)

Headache

45.

Which drug class does Prednisone belong to?

a)

NSAID

b)

Opioid

c)

Glucocorticoid

d)

Antibiotic

46.

True or False: Bacteriostatic drugs kill bacteria directly.

a)

True

b)

False

47.

What is the primary use of Donepezil (Aricept)?

a)

To cure Alzheimer's disease

b)

To slow the progression of Alzheimer's symptoms

c)

To treat Parkinson's tremors

d)

To treat clinical depression

48.

A patient has been taking a benzodiazepine for 10 years. What is the biggest risk if they stop suddenly?

a)

Excessive sleep

b)

Seizures and withdrawal

c)

Improvement in memory

d)

Increased appetite

49.

Which antibiotic class is associated with potential ototoxicity and nephrotoxicity?

a)

Penicillins

b)

Aminoglycosides (e.g., Gentamicin)

c)

Macrolides

d)

Cephalosporins

50.

True or False: Intravenous (IV) administration provides the fastest absorption of a medication.

a)

True

b)

False

51.

Which drug is commonly used to treat a urinary tract infection (UTI) and requires the patient to drink plenty of fluids to prevent crystalluria?

a)

Penicillin

b)

Trimethoprim-Sulfamethoxazole (Bactrim)

c)

Erythromycin

d)

Vancomycin

52.

True or False: A "Loading Dose" is a large initial dose given to reach the therapeutic range quickly.

a)

True

b)

False

53.

What is a common side effect of Tetracycline that nurses should warn young patients about?

a)

Orange urine

b)

Discoloration of permanent teeth

c)

Extreme hair loss

d)

Hearing loss

54.

A patient is prescribed Rifampin for Tuberculosis. What normal side effect should the nurse mention?

a)

Severe diarrhea

b)

Orange-red discoloration of urine and tears

c)

Insomnia

55.

Which of the following are adverse effects of Gentamicin? (Select All That Apply)

a)

Ototoxicity

b)

Nephrotoxicity

c)

Hypertension

d)

Hyperglycemia

56.

True or False: Patients taking Metronidazole (Flagyl) must avoid alcohol to prevent a disulfiram-like reaction (severe vomiting).

a)

True

b)

False

57.

Which drug is the "rescue" medication for an acute asthma attack?

a)

Montelukast

b)

Albuterol

c)

Tiotropium

d)

Fluticasone

58.

The nurse is teaching a patient about Theophylline. Which substance should the patient avoid?

a)

Apple juice

b)

Caffeine

c)

Leafy greens

d)

Dairy products

59.

Which medication is an example of an Inhaled Anticholinergic used for COPD?

a)

Albuterol

b)

Ipratropium (Atrovent)

c)

Salmeterol

d)

Guaifenesin

60.

True or False: Glucocorticoids (Steroids) can cause blood glucose levels to rise (Hyperglycemia).

a)

True

b)

False

61.

A patient with a productive cough and thick secretions should be encouraged to take:

a)

Codeine

b)

Guaifenesin (Mucinex)

c)

Diphenhydramine

d)

Benzonatate

62.

What is the mechanism of action for a Proton Pump Inhibitor (PPI) like Pantoprazole?

a)

Neutralizes existing stomach acid

b)

Blocks the final step of acid production

c)

Coats the stomach lining

d)

Increases GI motility

63.

Which laxative is considered a "Bulk-forming" laxative and is safest for long-term use?

a)

Bisacodyl

b)

Psyllium (Metamucil)

c)

Magnesium Citrate

d)

Castor Oil

64.

True or False: Diphenoxylate with Atropine (Lomotil) is used to treat constipation.

a)

True

b)

False

65.

A patient is taking Ondansetron (Zofran). What is the primary indication for this drug?

a)

Hypertension

b)

Nausea and Vomiting

c)

Bacterial infection

d)

Pain relief

66.

Which of the following is a common side effect of Aluminum-containing antacids?

a)

Diarrhea

b)

Constipation

c)

Fluid retention

d)

Increased heart rate

67.

True or False: Sucralfate should be taken on an empty stomach to allow it to coat the gastric ulcer.

a)

True

b)

False

68.

When administering Digoxin, the nurse must monitor for "Digoxin Toxicity." Signs include: (Select All That Apply)

a)

Yellow/Green halos in vision

b)

Bradycardia

c)

Nausea/Vomiting

d)

Tachycardia

69.

Which lab value must be monitored for a patient on Heparin therapy?

a)

PT/INR

b)

aPTT

c)

Liver enzymes

d)

Hemoglobin A1C

70.

True or False: The antidote for Warfarin (Coumadin) is Vitamin K.

a)

True

b)

False

71.

Which drug is an HMG-CoA Reductase Inhibitor used to lower cholesterol?

a)

Furosemide

b)

Atorvastatin

c)

Lisinopril

d)

Metoprolol

72.

What is a potentially life-threatening side effect of ACE Inhibitors (e.g., Lisinopril)?

a)

Tachycardia

b)

Angioedema (swelling of face/tongue)

c)

Hypokalemia

d)

Constipation

73.

True or False: Nitroglycerin sublingual tablets should be swallowed with a full glass of water.

a)

True

b)

False

74.

A patient is taking Spironolactone. The nurse should monitor for which electrolyte imbalance?

a)

Hypokalemia

b)

Hyperkalemia

c)

Hyponatremia

d)

Hypocalcemia

75.

Which medication is the first-line treatment for Type 2 Diabetes?

a)

Insulin Lispro

b)

Metformin

c)

Glucagon

d)

Dexamethasone

76.

True or False: Glargine (Lantus) insulin is long-acting and has no peak.

a)

True

b)

False

77.

Which type of insulin is administered IV for the treatment of Diabetic Ketoacidosis (DKA)?

a)

NPH

b)

Regular (Humulin R)

c)

Lantus

d)

Levemir

78.

Signs of Hypoglycemia (low blood sugar) include: (Select All That Apply)

a)

Shakiness/Tremors

b)

Sweating (Diaphoresis)

c)

Extreme thirst

d)

Confusion

79.

True or False: Levothyroxine (Synthroid) should be taken at bedtime with food.

a)

True

b)

False

80.

What is the primary risk of taking broad-spectrum antibiotics for a long period?

a)

Weight gain

b)

Development of C. difficile (Superinfection)

c)

Hypertension

d)

Improved immunity

81.

Which of the following is the antidote for Benzodiazepine overdose?

a)

Naloxone

b)

Flumazenil

c)

Atropine

d)

Digoxin immune fab

82.

True or False: Aminoglycosides (like Amikacin) can be given orally to treat systemic infections.

a)

True

b)

False

83.

A patient is taking Phenazopyridine (Pyridium) for a UTI. What should the nurse teach?

a)

This drug will cure the infection.

b)

It may turn urine reddish-orange.

c)

Take it only once a week.

d)

Stop taking it if your skin turns yellow.

84.

What is the primary purpose of a "Peak and Trough" level?

a)

To see how much the drug costs.

b)

To ensure the drug level is therapeutic and not toxic.

c)

To check for allergic reactions.

d)

To measure the patient's heart rate.

85.

Which drug class is used to treat "Dry Eyes" and "Dry Mouth" symptoms in Sjögren's, but is generally avoided in patients with Glaucoma?

a)

Cholinergic agonists

b)

Beta-blockers

c)

Anticholinergics

d)

Loop diuretics

86.

True or False: Nystatin is commonly used as a "swish and swallow" for oral candidiasis (thrush).

a)

True

b)

False

87.

Which drug is a Potassium-sparing diuretic?

a)

Hydrochlorothiazide

b)

Furosemide

c)

Spironolactone

d)

Mannitol

88.

What is the priority nursing action if a patient complains of itching and hives during an IV antibiotic infusion?

a)

Slow the infusion down.

b)

Stop the infusion immediately.

c)

Administer an antipyretic.

d)

Tell the patient this is a normal side effect.

89.

True or False: Aspirin inhibits platelet aggregation for the life of the platelet (7–10 days).

a)

True

b)

False

90.

A patient is prescribed Iron supplements (Ferrous Sulfate). The nurse should advise them to:

a)

Take it with milk.

b)

Take it with Orange Juice (Vitamin C) to increase absorption.

c)

Expect bright red stools.

d)

Lie flat for 30 minutes after taking it.

91.

Which medication is used to treat Herpes Simplex Virus (HSV) or Varicella-Zoster?

a)

Amoxicillin

b)

Acyclovir

c)

Fluconazole

d)

Metronidazole

92.

True or False: Allopurinol is used to treat an acute gout attack.

a)

True

b)

False

93.

Which of the following is an adverse effect of inhaled corticosteroids?

a)

Tachycardia

b)

Oral Candidiasis (Thrush)

c)

Hypoglycemia

d)

Diarrhea

94.

The "Three Ps" of Diabetes (Hyperglycemia) are: (Select All That Apply)

a)

Polyuria (increased urination)

b)

Polydipsia (increased thirst)

c)

Polyphagia (increased hunger)

d)

Polyneuropathy

95.

What is the mechanism of action for Heparin?

a)

Dissolves existing clots.

b)

Prevents the formation of new clots.

c)

Increases platelet count.

d)

Constricts blood vessels.

96.

True or False: Furosemide (Lasix) should be administered in the evening to help the patient sleep.

a)

True

b)

False

97.

Which medication is used as a mood stabilizer for Bipolar Disorder?

a)

Haloperidol

b)

Lithium

c)

Lorazepam

d)

Fluoxetine

98.

A patient has an order for "NPO." This means the patient should:

a)

Take meds only with water.

b)

Take nothing by mouth.

c)

Take meds only via IV.

d)

Eat only clear liquids.

99.

True or False: Trough levels are drawn 30 minutes before the next dose is administered.

a)

True

b)

False

100.

Which of the following is a symptom of "Extrapyramidal Symptoms" (EPS) from antipsychotics?

a)

Hypertension

b)

Acute Dystonia (muscle spasms)

c)

Excessive sleeping

d)

Diarrhea

101.

Respiratory depression is the most life-threatening effect.

a)

True

b)

False

102.

COX-1 protects the stomach lining.

a)

True

b)

False

103.

Caffeine increases stimulatory effects.

a)

True

b)

False

104.

Bradykinesia, muscle rigidity, and pill-rolling tremors are hallmark motor symptoms.

a)

True

b)

False

105.

Atropine is the prototype anticholinergic.

a)

True

b)

False

106.

Cephalosporins have a similar ring structure.

a)

True

b)

False

107.

Antagonists block receptors while agonists produce a response.

a)

True

b)

False

108.

Antibiotic-associated superinfections can include Clostridioides difficile infections or oral thrush.

a)

True

b)

False

109.

When both are ordered for inhalation therapy, give the bronchodilator first to "open the door" for the steroid.

a)

True

b)

False

110.

Furosemide wastes potassium.

a)

True

b)

False

111.

Antitussive means "against cough."

a)

True

b)

False

112.

Sudden changes in vitamin K intake affect clotting time.

a)

True

b)

False

113.

Common adverse effects can include tinnitus, dizziness, and headache.

a)

True

b)

False

114.

Bacteriostatic agents inhibit growth, while bactericidal agents kill.

a)

True

b)

False

115.

Withdrawal can lead to status epilepticus.

a)

True

b)

False

116.

Ototoxicity and nephrotoxicity are notable risks with some medications.

a)

True

b)

False

117.

Caffeine is a xanthine, like theophylline.

a)

True

b)

False

118.

Aluminum salts tend to cause constipation, while magnesium salts tend to cause diarrhea.

a)

True

b)

False

119.

Yellow or green halos, bradycardia, and nausea/vomiting are classic toxicity signs.

a)

True

b)

False

120.

Sublingual tablets must dissolve under the tongue.

a)

True

b)

False

121.

Shakiness, sweating, and confusion are common signs of low blood glucose.

a)

True

b)

False

122.

Diuretics are typically given in the morning to prevent nocturia.

a)

True

b)

False

123.

In suspected anaphylaxis, first stop the source of exposure.

a)

True

b)

False

124.

Polyuria, polydipsia, and polyphagia are classic symptoms seen with high blood glucose.

a)

True

b)

False

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