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Benzodiazepines Quiz

Total questions: 20

Worksheet time: 10mins

Name
Class
Date
1.

Benzodiazepines produce their action by enhancing the effect of

a)

Glycine

b)

Serotonin

c)

GABA

d)

Dopamine

2.

Benzodiazepines act at which receptor site?

a)

NMDA receptor

b)

GABA-A receptor

c)

GABA-B receptor

d)

Opioid receptor

3.

Mechanism of action of benzodiazepines involves

a)

Increasing duration of chloride channel opening

b)

Increasing frequency of chloride channel opening

c)

Blocking sodium channels

d)

Inhibiting GABA synthesis

4.

Short-acting benzodiazepine is

a)

Diazepam

b)

Chlordiazepoxide

c)

Lorazepam

d)

Triazolam

5.

Long-acting benzodiazepine is

a)

Midazolam

b)

Oxazepam

c)

Diazepam

d)

Temazepam

6.

Benzodiazepines produce all of the following effects EXCEPT

a)

Anxiolysis

b)

Sedation

c)

Muscle relaxation

d)

Analgesia

7.

Common therapeutic use of benzodiazepines is

a)

Schizophrenia

b)

Anxiety disorders

c)

Depression

d)

Psychosis

8.

Benzodiazepines are used as preanesthetic medication because they cause

a)

Analgesia

b)

Amnesia and sedation

c)

Muscle paralysis

d)

Local anesthesia

9.

Drug of choice for acute status epilepticus is

a)

Phenytoin

b)

Phenobarbitone

c)

Diazepam

d)

Valproate

10.

Benzodiazepines produce muscle relaxation by action at

a)

Neuromuscular junction

b)

Spinal cord

c)

Muscle fibers

d)

Cerebellum

11.

Major adverse effect of benzodiazepines is

a)

Respiratory stimulation

b)

Dependence and tolerance

c)

Severe hepatotoxicity

d)

Renal failure

12.

Benzodiazepine overdose is relatively safe because of

a)

No CNS depression

b)

Ceiling effect on respiratory depression

c)

Rapid metabolism

d)

High therapeutic index

13.

Flumazenil is used as an antidote for

a)

Barbiturate overdose

b)

Opioid overdose

c)

Benzodiazepine overdose

d)

Alcohol intoxication

14.

Benzodiazepines cause less respiratory depression than barbiturates because they

a)

Act directly on GABA receptors

b)

Enhance GABA action only in presence of GABA

c)

Block chloride channels

d)

Inhibit glutamate

15.

Barbiturates differ from benzodiazepines by

a)

Lower abuse potential

b)

Less enzyme induction

c)

Greater safety margin

d)

Ability to induce hepatic enzymes

16.

Benzodiazepines do NOT induce

a)

Anxiolysis

b)

Muscle relaxation

c)

Hepatic enzyme induction

d)

Sedation

17.

Benzodiazepines are preferred over barbiturates because they

a)

Have analgesic action

b)

Produce deep anesthesia

c)

Have wider therapeutic index

d)

Are cheaper

18.

Abrupt withdrawal of benzodiazepines may cause

a)

Hypertension only

b)

Withdrawal seizures

c)

Renal failure

d)

Hepatic coma

19.

Benzodiazepines are contraindicated in

a)

Anxiety disorders

b)

Insomnia

c)

Severe respiratory insufficiency

d)

Status epilepticus

20.

Benzodiazepines produce amnesia mainly of type

a)

Retrograde

b)

Anterograde

c)

Global

d)

No amnesia