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WorksheetsMCQs on Puberty
Total questions: 16
Worksheet time: 8mins
Q1. Which of the following is the earliest clinical sign of puberty in boys ?
A. Pubic hair development
B. Voice deepening
C. Testicular enlargement
D. Penile lengthening
E. Growth spurt
Q2. Menarche usually occurs at which Tanner stage ?
A. Tanner I
B. Tanner II
C. Tanner III
D. Tanner IV
E. Tanner V
Q3. Which hormone is responsible for initiating puberty ?
A. LH
B. FSH
C. Estradiol
D. GnRH
E. DHEA
Q4. Precocious puberty is defined as onset of secondary sexual characteristics before:
A. 7 years in girls, 8 years in boys
B. 8 years in girls, 9 years in boys
C. 9 years in girls, 10 years in boys
D. 10 years in girls, 11 years in boys
E. 11 years in girls, 12 years in boys
Q5. Which finding suggests central precocious puberty ?
A. Suppressed LH after GnRH stimulation
B. Advanced bone age with low LH
C. Pubertal LH response to GnRH
D. Elevated DHEAS only
E. Normal growth velocity
Q6. Which condition causes gonadotropin-independent precocious puberty ?
A. Craniopharyngioma
B. Hypothalamic hamartoma
C. Congenital adrenal hyperplasia
D. Idiopathic central puberty
E. Kallmann syndrome
Q7. The most useful initial investigation in a child with suspected precocious puberty is:
A. Bone age X-ray
B. MRI brain
C. Serum oestradiol/testosterone
D. Pelvic ultrasound
E. GnRH Stimulation test
Q8. The treatment of choice for central precocious puberty is:
A. Aromatase inhibitors
B. GnRH analogues
C. Oestrogen blockers
D. Corticosteroids
E. Growth hormone
Q9. In normal puberty, the peak height velocity occurs:
A. Before secondary sexual characteristics
B. At the onset of puberty in both sexes
C. Earlier in girls than boys
D. After menarche
E. Only in boys
Q10. A 6-year-old girl presents with breast development and pubic hair. She is tall for age with advanced bone age. LH rises after GnRH stimulation.
Most likely diagnosis is?
A. Premature thelarche
B. Peripheral precocious puberty
C. Central precocious puberty
D. McCune-Albright syndrome
E. Congenital adrenal hyperplasia
Q11. Which hormone is primarily responsible for adrenarche?
A. Cortisol
B. Aldosterone
C. Testosterone
D. DHEA
E. Oestradiol
Q12. A 3-year-old girl has isolated breast development with normal growth and bone age. The most likely diagnosis is:
A. Central precocious puberty
B. Peripheral precocious puberty
C. Premature thelarche
D. Congenital adrenal hyperplasia
E. McCune-Albright syndrome
Q13. MRI brain is mandatory in which case of precocious puberty?
A. 7-year-old girl with slowly progressive puberty
B. 6-year-old boy with pubertal signs
C. 8-year-old girl with isolated thelarche
D. 9-year-old girl with menarche
E. 10-year-old boy with normal puberty
Q14. Which feature distinguishes true (central) precocious puberty from pseudo-precocious puberty?
A. Advanced bone age
B. Early secondary sexual characteristics
C. Pubertal growth spurt
D. Pubertal LH response to GnRH
E. Tall stature
Q15. Which pattern of growth is typical in central precocious puberty?
A. Normal growth velocity with delayed bone age
B. Reduced growth velocity with normal bone age
C. Increased growth velocity with advanced bone age
C. Increased growth velocity with advanced bone age
E. Reduced growth velocity with advanced bone age
Q16. Which triad is characteristic of McCune-Albright syndrome?
A. Short stature, obesity, hypogonadism
B. Precocious puberty, café-au-lait spots, fibrous dysplasia
C. Delayed puberty, anosmia, cleft palate
D. Ambiguous genitalia, salt-wasting, hyperpigmentation
E. Tall stature, gynaecomastia, small testes
