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Clinical Chemistry Quiz (Part 2)

Total questions: 50

Worksheet time: 25mins

Name
Class
Date
1.

Electrolytes important for acid-base balance:

a)

Sodium, chloride, potassium

b)

Bicarbonate, potassium, chloride

c)

Potassium, magnesium, calcium

d)

Calcium, magnesium

2.

Electrolytes important for blood coagulation:

a)

Sodium, chloride, potassium

b)

Bicarbonate, potassium, chloride

c)

Calcium, magnesium

d)

Magnesium, phosphate

3.

Which electrolyte is significantly involved in the transmission of nerve impulses?

a)

Iron

b)

Phosphorus

c)

Potassium

d)

Sodium

4.

Hyponatremia can be classified according to:

a)

Chloride values

b)

Anion gap

c)

Glucose determination

d)

Plasma/serum osmolality

5.

Sodium produces which color in a flame?

a)

Red

b)

Violet

c)

Yellow

d)

Magnesium

6.

Which method is not affected by excess lipids or proteins causing falsely decreased sodium (pseudohyponatremia) measurement?

a)

Direct ISE

b)

Indirect ISE

c)

Flame photometry

d)

None of these

7.

It is a major anion that counterbalances the major cation, sodium:

a)

Potassium

b)

Magnesium

c)

Chloride

d)

Bicarbonate

8.

Conditions associated with elevated anion gap may be caused by:

a)

Hypoalbuminemia

b)

Ketoacidosis in starvation or diabetes

c)

Uremia/renal failure

d)

Methanol, ethanol, ethylene glycol, or salicylate poisoning

e)

Lactic acidosis

9.

The normal ratio of carbonic acid to bicarbonate in arterial blood is:

a)

1:20

b)

7.7:6.1

c)

0.003:1.39

d)

20:1

10.

In the circulatory system, bicarbonate leaves the red blood cells and enters the plasma through an exchange mechanism with ____ to maintain electroneutrality.

a)

Chloride

b)

Carbonic acid

c)

Lactate

d)

Sodium

11.

An emphysema patient suffering from fluid accumulation in the alveolar spaces is likely to be in what metabolic state?

a)

Respiratory acidosis

b)

Metabolic acidosis

c)

Respiratory alkalosis

d)

Metabolic alkalosis

12.

Which of the following is the primary mechanism causing respiratory alkalosis?

a)

Renal failure

b)

Hyperventilation

c)

Congestive heart failure

d)

Too much bicarbonate

13.

The neurohypophysis is the:

a)

Hypothalamus

b)

Anterior pituitary

c)

Thyroid gland

d)

Posterior pituitary

14.

Which of the following produces hormones?
1. Anterior Pituitary gland

  1. 2. Posterior Pituitary Gland

  2. 3. Thyroid gland

  3. 4. Parathyroid gland

a)

1,2

b)

1,2,3

c)

1,,3,4

d)

1,2,3,4

15.

Prolactin, considered a stress hormone, has vital functions in relationship to reproduction. It is produced by the:

a)

Anterior pituitary gland

b)

Posterior pituitary gland

c)

Thyroid gland

d)

Ovaries

16.

Pituitary Cushing’s syndrome

a)

Increased ACTH and cortisol

b)

Decreased ACTH and cortisol

c)

Increased ACTH, decreased cortisol

d)

Decreased ACTH, increased cortisol

17.

Adrenal Cushing’s syndrome:

a)

Increased ACTH and cortisol

b)

Decreased ACTH and cortisol

c)

Increased ACTH, decreased cortisol

d)

Decreased ACTH, increased cortisol

18.

Its major action is to regulate renal free water excretion and, therefore, central role in water balance:

a)

Aldosterone

b)

Oxytocin

c)

Prolactin

d)

Vasopressin (ADH)

19.

Zona fasciculata (F-zone) cells, the middle layer of the adrenal cortex produces:

a)

Aldosterone

b)

Sulfate DHEAs

c)

Cortisol and cortisone

d)

All of these

20.

Decreased aldosterone:

a)

Low serum Na+ and K+

b)

High serum Na+ and K+

c)

Low serum Na+, high serum K+

d)

High serum Na+, low serum K

21.

The biologically most active, naturally occurring androgen is:

a)

Androstenedione

b)

Epiandrosterone

c)

Dehydroepiandrosterone

d)

Testosterone

22.

Most useful test for assessing thyroid function:

a)

TSH

b)

Serum T3 and T4

c)

Thyroglobulin

d)

Thyroid autoimmune antibodies

23.

The thyroid gland produces all of the following EXCEPT:

a)

TSH

b)

Thyroglobulin

c)

T3

d)

T4

24.

Subclinical hypothyroidism:

a)

Decreased T3 T4, decreased TSH

b)

Increased T3 T4, increased TSH

c)

Normal T3 T4, increased TSH

d)

Decreased T3 T4, increased TSH

25.

Body mass index of an overweight person:

a)

BMI <18.5 kg/m2

b)

BMI of 18.5 to 24.9 kg/m2

c)

BMI 25 to 29.9 kg/m2

d)

BMI >30kg/m2

26.

Which of the following tumor markers is used to monitor persons with breast cancer for recurrence of disease?

a)

Cathepsin-D

b)

Retinoblastoma gene

c)

CA-15-3

d)

Estrogen Receptor (ER)

27.

Estrogen and progesterone receptor assays are useful in assessing prognosis in which of the following?

a)

Ovarian cancer

b)

Endometriosis

c)

Breast cancer

d)

Amenorrhea

28.

Zinc protoporphyrin or free erythrocyte protoporphyrin measurements are useful to assess blood concentrations of:

a)

Lead

b)

Mercury

c)

Arsenic

d)

Beryllium

29.

The most serious effect of methanol ingestion is:

a)

Hallucinations

b)

Blindness

c)

Psychosis

d)

liver damage

30.

It is used for treatment of petit mal (absence seizure) and grand mal:

a)

Theophylline

b)

Lithium

c)

Valproic acid (Dapakene)

d)

Digoxin

31.

All of the following may be used to cleanse the skin when drawing blood for ethanol analysis, EXCEPT:

a)

Alcohol swab

b)

Merthiolate

c)

Soap and water

d)

Zephiran

32.

20 °C = ___ °F

a)

25

b)

53

c)

68

d)

86

33.

The primary product of hepatic metabolism of cocaine is:

a)

Morphine

b)

NAPA

c)

Benzoylecgonine

d)

Primidone

34.

Quantification of human chorionic gonadotropin (HCG) is useful in which of the following clinical findings?

a)

Threatened abortions

b)

Hydatidiform moles

c)

Chroiocarcinoma

d)

Testicular tumors

35.

All of the following are associated with false positive urine HCG test, except:

a)

Increased protein

b)

Penicillin

c)

Barbiturate

d)

Dilute urine

36.

Select the hormone that is associated with galactorrhea, pituitary adenoma and amenorrhea:

a)

Estradiol

b)

Progesterone

c)

Follicle-stimulating hormone

d)

Prolactin

37.

The most potent estrogen and considered to be the true ovarian hormone is:

a)

Estrone

b)

Estradiol

c)

Estriol

d)

Epiestriol

38.

The biologically most active, naturally occurring androgen is:

a)

DHEA

b)

Androstenedione

c)

Epiandrosterone

d)

Testosterone

39.

The KOBER REACTION is used in the assay of:

a)

Urinary estrogen

b)

Glucocorticoids

c)

Testosterone

d)

Epinephrine

40.

In the PORTER-SILBER ASSAY, the dihydroxyacetone side chain of the steroid hormone reacts with:

a)

Sulfuric acid-hydroquinonev and forms reddish-brown color

b)

M-dinitrobenzene and forms purple color

c)

Ceric and arsenite compound and forms a yellow product

d)

2, 4 -dinitrophenylhydrazene and forms a yellow derivative

41.

The assay employed for 17-ketosteroids, in which steroids react with m-dinitrobenzene in alcoholic KOH solution resulting to the formation of a purple color:

a)

Kober Reaction

b)

Zimmerman Reaction

c)

Porter-Silber Reaction

d)

Pisano Method

42.

It is used as an analgesic and antitussive:

a)

Cocaine

b)

Morphine

c)

Heroine

d)

Codeine

43.

Which of the following hyponatremia is not caused by increased sodium loss?

a)

Diuretic use

b)

Renal failure

c)

Potassium deficiency

d)

Severe burns

44.

Hyponatremia due to WATER IMBALANCE:

a)

Congestive heart failure

b)

Diuretic use

c)

Vomiting, diarrhea

d)

SIADH

45.

Which steroid hormone is essentially important in preparing the uterus for implantation if blastocyst and in maintaining pregnancy?

a)

Andostrenedione

b)

Progesterone

c)

Estriol

d)

HCG

46.

The signs and symptoms of this blood alcohol level in %w/v are mental confusion, dizziness and strongly impaired motor skills (staggering, slurred speech).

a)

0.09 – 0.25

b)

0.18 – 0.30

c)

0.27 – 0.40

d)

0.35 – 0.50

47.

A hormone that is also an enzyme

a)

Renin

b)

ADH

c)

TSH

d)

Cortisol

e)

NOTA

48.

Which if the following sets of values for repeat analyses of a QC sample reflects the best precision?

a)

50, 51, 52

b)

50, 52, 56

c)

48, 50, 52

d)

44, 50, 53

e)

Two of the above

49.

Lead toxicity is acquired through the following, except:

a)

Skin contact

b)

Animal bite

c)

Inhalation

d)

Ingestion

e)

Two of the above

50.

All of the following may be used to stain proteins, except:

a)

Bromphenol blue

b)

Coomasie blue R250

c)

Colloidal gold

d)

NOTA