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WorksheetsClinical Chemistry Quiz (Part 2)
Total questions: 50
Worksheet time: 25mins
Electrolytes important for acid-base balance:
Sodium, chloride, potassium
Bicarbonate, potassium, chloride
Potassium, magnesium, calcium
Calcium, magnesium
Electrolytes important for blood coagulation:
Sodium, chloride, potassium
Bicarbonate, potassium, chloride
Calcium, magnesium
Magnesium, phosphate
Which electrolyte is significantly involved in the transmission of nerve impulses?
Iron
Phosphorus
Potassium
Sodium
Hyponatremia can be classified according to:
Chloride values
Anion gap
Glucose determination
Plasma/serum osmolality
Sodium produces which color in a flame?
Red
Violet
Yellow
Magnesium
Which method is not affected by excess lipids or proteins causing falsely decreased sodium (pseudohyponatremia) measurement?
Direct ISE
Indirect ISE
Flame photometry
None of these
It is a major anion that counterbalances the major cation, sodium:
Potassium
Magnesium
Chloride
Bicarbonate
Conditions associated with elevated anion gap may be caused by:
Hypoalbuminemia
Ketoacidosis in starvation or diabetes
Uremia/renal failure
Methanol, ethanol, ethylene glycol, or salicylate poisoning
Lactic acidosis
The normal ratio of carbonic acid to bicarbonate in arterial blood is:
1:20
7.7:6.1
0.003:1.39
20:1
In the circulatory system, bicarbonate leaves the red blood cells and enters the plasma through an exchange mechanism with ____ to maintain electroneutrality.
Chloride
Carbonic acid
Lactate
Sodium
An emphysema patient suffering from fluid accumulation in the alveolar spaces is likely to be in what metabolic state?
Respiratory acidosis
Metabolic acidosis
Respiratory alkalosis
Metabolic alkalosis
Which of the following is the primary mechanism causing respiratory alkalosis?
Renal failure
Hyperventilation
Congestive heart failure
Too much bicarbonate
The neurohypophysis is the:
Hypothalamus
Anterior pituitary
Thyroid gland
Posterior pituitary
Which of the following produces hormones?
1. Anterior Pituitary gland
2. Posterior Pituitary Gland
3. Thyroid gland
4. Parathyroid gland
1,2
1,2,3
1,,3,4
1,2,3,4
Prolactin, considered a stress hormone, has vital functions in relationship to reproduction. It is produced by the:
Anterior pituitary gland
Posterior pituitary gland
Thyroid gland
Ovaries
Pituitary Cushing’s syndrome
Increased ACTH and cortisol
Decreased ACTH and cortisol
Increased ACTH, decreased cortisol
Decreased ACTH, increased cortisol
Adrenal Cushing’s syndrome:
Increased ACTH and cortisol
Decreased ACTH and cortisol
Increased ACTH, decreased cortisol
Decreased ACTH, increased cortisol
Its major action is to regulate renal free water excretion and, therefore, central role in water balance:
Aldosterone
Oxytocin
Prolactin
Vasopressin (ADH)
Zona fasciculata (F-zone) cells, the middle layer of the adrenal cortex produces:
Aldosterone
Sulfate DHEAs
Cortisol and cortisone
All of these
Decreased aldosterone:
Low serum Na+ and K+
High serum Na+ and K+
Low serum Na+, high serum K+
High serum Na+, low serum K
The biologically most active, naturally occurring androgen is:
Androstenedione
Epiandrosterone
Dehydroepiandrosterone
Testosterone
Most useful test for assessing thyroid function:
TSH
Serum T3 and T4
Thyroglobulin
Thyroid autoimmune antibodies
The thyroid gland produces all of the following EXCEPT:
TSH
Thyroglobulin
T3
T4
Subclinical hypothyroidism:
Decreased T3 T4, decreased TSH
Increased T3 T4, increased TSH
Normal T3 T4, increased TSH
Decreased T3 T4, increased TSH
Body mass index of an overweight person:
BMI <18.5 kg/m2
BMI of 18.5 to 24.9 kg/m2
BMI 25 to 29.9 kg/m2
BMI >30kg/m2
Which of the following tumor markers is used to monitor persons with breast cancer for recurrence of disease?
Cathepsin-D
Retinoblastoma gene
CA-15-3
Estrogen Receptor (ER)
Estrogen and progesterone receptor assays are useful in assessing prognosis in which of the following?
Ovarian cancer
Endometriosis
Breast cancer
Amenorrhea
Zinc protoporphyrin or free erythrocyte protoporphyrin measurements are useful to assess blood concentrations of:
Lead
Mercury
Arsenic
Beryllium
The most serious effect of methanol ingestion is:
Hallucinations
Blindness
Psychosis
liver damage
It is used for treatment of petit mal (absence seizure) and grand mal:
Theophylline
Lithium
Valproic acid (Dapakene)
Digoxin
All of the following may be used to cleanse the skin when drawing blood for ethanol analysis, EXCEPT:
Alcohol swab
Merthiolate
Soap and water
Zephiran
20 °C = ___ °F
25
53
68
86
The primary product of hepatic metabolism of cocaine is:
Morphine
NAPA
Benzoylecgonine
Primidone
Quantification of human chorionic gonadotropin (HCG) is useful in which of the following clinical findings?
Threatened abortions
Hydatidiform moles
Chroiocarcinoma
Testicular tumors
All of the following are associated with false positive urine HCG test, except:
Increased protein
Penicillin
Barbiturate
Dilute urine
Select the hormone that is associated with galactorrhea, pituitary adenoma and amenorrhea:
Estradiol
Progesterone
Follicle-stimulating hormone
Prolactin
The most potent estrogen and considered to be the true ovarian hormone is:
Estrone
Estradiol
Estriol
Epiestriol
The biologically most active, naturally occurring androgen is:
DHEA
Androstenedione
Epiandrosterone
Testosterone
The KOBER REACTION is used in the assay of:
Urinary estrogen
Glucocorticoids
Testosterone
Epinephrine
In the PORTER-SILBER ASSAY, the dihydroxyacetone side chain of the steroid hormone reacts with:
Sulfuric acid-hydroquinonev and forms reddish-brown color
M-dinitrobenzene and forms purple color
Ceric and arsenite compound and forms a yellow product
2, 4 -dinitrophenylhydrazene and forms a yellow derivative
The assay employed for 17-ketosteroids, in which steroids react with m-dinitrobenzene in alcoholic KOH solution resulting to the formation of a purple color:
Kober Reaction
Zimmerman Reaction
Porter-Silber Reaction
Pisano Method
It is used as an analgesic and antitussive:
Cocaine
Morphine
Heroine
Codeine
Which of the following hyponatremia is not caused by increased sodium loss?
Diuretic use
Renal failure
Potassium deficiency
Severe burns
Hyponatremia due to WATER IMBALANCE:
Congestive heart failure
Diuretic use
Vomiting, diarrhea
SIADH
Which steroid hormone is essentially important in preparing the uterus for implantation if blastocyst and in maintaining pregnancy?
Andostrenedione
Progesterone
Estriol
HCG
The signs and symptoms of this blood alcohol level in %w/v are mental confusion, dizziness and strongly impaired motor skills (staggering, slurred speech).
0.09 – 0.25
0.18 – 0.30
0.27 – 0.40
0.35 – 0.50
A hormone that is also an enzyme
Renin
ADH
TSH
Cortisol
NOTA
Which if the following sets of values for repeat analyses of a QC sample reflects the best precision?
50, 51, 52
50, 52, 56
48, 50, 52
44, 50, 53
Two of the above
Lead toxicity is acquired through the following, except:
Skin contact
Animal bite
Inhalation
Ingestion
Two of the above
All of the following may be used to stain proteins, except:
Bromphenol blue
Coomasie blue R250
Colloidal gold
NOTA
