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Worksheets

GIT

Total questions: 80

Worksheet time: 3600secs

Name
Class
Date
1.

A patient with achlorhydria will have decreased release of which hormone?

a)

Secretin

b)

Gastrin

c)

CCK

d)

Motilin

2.

Pancreatic enzyme secretion is most strongly stimulated by:

a)

Gastrin

b)

CCK

c)

Somatostatin

d)

VIP

3.

Bile salts are synthesized in the liver from:

a)

Triglycerides

b)

Cholesterol

c)

Amino acids

d)

Glucose

4.

A blockage of the common bile duct leads to elevated:

a)

Amylase

b)

Lipase

c)

Bilirubin

d)

Trypsin

5.

Secretin primarily increases:

a)

HCl secretion

b)

Bicarbonate secretion

c)

Pepsinogen release

d)

Motility

6.

The primary site of digestive enzyme action for fats is:

a)

Stomach

b)

Duodenum

c)

Jejunum

d)

Ileum

7.

Gastric inhibitory peptide (GIP) is released in response to:

a)

Fat & glucose in the small intestine

b)

Acid in stomach

c)

Distension of stomach

d)

Amino acids in colon

8.

Trypsinogen is activated by:

a)

Enterokinase

b)

Pepsin

c)

HCl

d)

Amylase

9.

Failure of CCK secretion would most impair digestion of:

a)

Carbohydrates

b)

Proteins

c)

Fats

d)

Electrolytes

10.

Secretin release is triggered by:

a)

Fat in stomach

b)

Acid in duodenum

c)

Protein in jejunum

d)

Distension of ileum

11.

A patient with pancreatic insufficiency would have malabsorption of:

a)

Vitamins A, D, E, K

b)

B12 only

c)

Iron only

d)

Water-soluble vitamins

12.

Bile salts facilitate fat absorption by forming:

a)

Micelles

b)

Chylomicrons

c)

Proteosomes

d)

Liposomes

13.

Which hormone increases biliary secretion?

a)

Motilin

b)

Secretin

c)

Ghrelin

d)

Insulin

14.

G cells in the stomach secrete:

a)

CCK

b)

Gastrin

c)

Secretin

d)

Somatostatin

15.

Somatostatin inhibits secretion of:

a)

Gastrin

b)

Insulin

c)

Glucagon

d)

All of the above

16.

The cephalic phase of gastric secretion is mediated by:

a)

CCK

b)

Vagus nerve

c)

Secretin

d)

Gastrin

17.

Pepsinogen is secreted by:

a)

Parietal cells

b)

Chief cells

c)

G cells

d)

D cells

18.

The primary stimulant for HCl secretion is:

a)

Secretin

b)

Gastrin

c)

GIP

d)

VIP

19.

Failure of the sphincter of Oddi to relax would impair:

a)

Pancreatic enzyme delivery

b)

Bile into duodenum

c)

Both A & B

d)

Gastric emptying

20.

A patient with Zollinger–Ellison syndrome has high:

a)

Gastrin

b)

Secretin

c)

CCK

d)

Motilin

21.

Pancreatic secretion with high bicarbonate and low enzymes occurs in response to:

a)

Secretin

b)

CCK

c)

Gastrin

d)

Motilin

22.

Enterokinase is located on the brush border of:

a)

Ileum

b)

Jejunum

c)

Duodenum

d)

Colon

23.

The major end product of starch digestion is:

a)

Glucose

b)

Lactose

c)

Maltose

d)

Fructose

24.

CCK release is MOST sensitive to:

a)

Acid

b)

Fatty acids

c)

Proteins

d)

Monosaccharides

25.

A deficiency in bile salts leads to malabsorption of:

a)

Carbohydrates

b)

Proteins

c)

Fats

d)

Vitamins B & C

26.

HCl secretion is inhibited by:

a)

Gastrin

b)

Histamine

c)

Secretin

d)

ACh

27.

A drug that blocks histamine H2 receptors reduces:

a)

Gastric emptying

b)

Bile secretion

c)

HCl secretion

d)

Pancreatic enzyme secretion

28.

The major pancreatic enzyme for fat digestion is:

a)

Amylase

b)

Lipase

c)

Trypsin

d)

Elastase

29.

Motilin increases:

a)

Pancreatic secretions

b)

Gastric motility during fasting

c)

Bile secretion

d)

Insulin release

30.

Digestion of triglycerides begins in the:

a)

Mouth

b)

Stomach

c)

Duodenum

d)

Jejunum

31.

Which hormone increases insulin release after a meal?

a)

CCK

b)

GIP

c)

Secretin

d)

Gastrin

32.

Bile is stored in the:

a)

Pancreas

b)

Gallbladder

c)

Duodenum

d)

Liver sinusoids

33.

A pancreatic duct obstruction will cause elevated:

a)

ALT

b)

Lipase

c)

Amylase

d)

Bilirubin

34.

Intrinsic factor is necessary for absorption of:

a)

Iron

b)

B12

c)

Folate

d)

Calcium

35.

The migrating motor complex is stimulated by:

a)

Motilin

b)

Gastrin

c)

CCK

d)

Secretin

36.

Gastric phase of secretion contributes what % of total gastric secretion?

a)

10%

b)

30%

c)

50%

d)

70%

37.

Enterogastric reflex decreases:

a)

Gastric emptying

b)

Pancreatic secretion

c)

Bile secretion

d)

Intestinal motility

38.

VIP causes:

a)

Increased HCl

b)

Increased pancreatic secretion

c)

Increased bile salt synthesis

d)

Smooth muscle relaxation

39.

A lack of ileal bile salt absorption leads to:

a)

Constipation

b)

Steatorrhea

c)

High B12 absorption

d)

Hypoglycemia

40.

Gastric acid secretion at basal state is mostly stimulated by:

a)

Histamine

b)

CCK

c)

Secretin

d)

GIP

41.

The hormone that inhibits gallbladder contraction is:

a)

Somatostatin

b)

CCK

c)

Gastrin

d)

Motilin

42.

Pancreatic acinar cells secrete:

a)

Bicarbonate

b)

Enzymes

c)

Hormones

d)

Bile salts

43.

The stimulus for bicarbonate secretion in the pancreas is:

a)

Gastric acid

b)

Fat in stomach

c)

Glucose

d)

Amino acids

44.

Trypsin inhibitor in pancreatic juice prevents:

a)

Acid damage

b)

Premature activation

c)

Bicarbonate loss

d)

CCK release

45.

Gallbladder emptying occurs mainly in response to:

a)

Secretin

b)

CCK

c)

Gastrin

d)

GIP

46.

Which enzyme digests proteins in the small intestine?

a)

Amylase

b)

Lipase

c)

Peptidases

d)

Lactase

47.

The pancreas secretes enzymes in a(n) _____ form:

a)

Active

b)

Proenzyme

c)

Hormonal

d)

Glycolytic

48.

The “ileal brake” mechanism slows motility when:

a)

Fat present in ileum

b)

Acid in duodenum

c)

Carbohydrates in jejunum

d)

Sodium in colon

49.

Pepsin works best at pH:

a)

1–3

b)

6–7

c)

8–9

d)

4–5

50.

Gastric mucosal cells that secrete pepsinogen are:

a)

Parietal cells

b)

Chief cells

c)

G cells

d)

Enterochromaffin cells

51.

Secretin release mainly occurs from the:

a)

Duodenum

b)

Stomach

c)

Colon

d)

Esophagus

52.

CCK also stimulates:

a)

Pancreatic enzyme secretion

b)

Gastric HCl

c)

Large intestine absorption

d)

Hepatic glucose output

53.

Hepatocytes produce:

a)

Gastrin

b)

Bile

c)

Insulin

d)

Amylase

54.

The main stimulus for gastric motility is:

a)

Food presence

b)

Secretin

c)

Passive diffusion

d)

Glucagon

55.

A patient with CFTR mutation (cystic fibrosis) often has:

a)

Excess bile

b)

Thick pancreatic secretions

c)

Excess bicarbonate

d)

Low gastrin

56.

The hormone that increases pancreatic bicarbonate secretion is:

a)

Secretin

b)

CCK

c)

Gastrin

d)

Motilin

57.

The main product of carbohydrate digestion absorbed is:

a)

Sucrose

b)

Glucose

c)

Maltose

d)

Starch

58.

Enterohepatic circulation recycles:

a)

Bile salts

b)

Pepsinogen

c)

Trypsinogen

d)

Amylase

59.

The major ion in pancreatic juice is:

a)

Cl−

b)

HCO3−

c)

Na+

d)

Ca2+

60.

A decrease in bile acids reduces:

a)

Water absorption

b)

Fat absorption

c)

Protein digestion

d)

Carbohydrate digestion

61.

Pancreatic duct cells secrete:

a)

Enzymes

b)

Bicarbonate

c)

Gastrin

d)

Pepsin

62.

Gastric secretion of HCl is directly stimulated by:

a)

Secretin

b)

Histamine

c)

Motilin

d)

CCK

63.

The major buffering component of pancreatic juice is:

a)

NaCl

b)

HCO3−

c)

Amylase

d)

Trypsin

64.

A patient with ileal resection will have deficiency of:

a)

Fat-soluble vitamins

b)

Glucose

c)

Amino acids

d)

Iron

65.

Brunner’s glands secrete:

a)

Mucus & bicarbonate

b)

Gastrin

c)

Bile

d)

Pancreatic enzymes

66.

The vagovagal reflex enhances:

a)

Gastric secretion

b)

Pancreatic enzymes

c)

Bile release

d)

All of the above

67.

A patient with decreased CCK would have:

a)

Poor fat digestion

b)

High pepsinogen

c)

High HCl

d)

Low bicarbonate

68.

Gastric acid promotes absorption of:

a)

Iron

b)

B12

c)

Fatty acids

d)

Calcium

69.

Trypsinogen → trypsin conversion occurs in the:

a)

Small intestine

b)

Stomach

c)

Pancreas

d)

Liver

70.

Secretin’s main role is to:

a)

Neutralize acid in duodenum

b)

Increase HCl

c)

Increase motilin

d)

Inhibit bile

71.

A patient with gastric bypass may have deficiency of:

a)

B12

b)

Glucose

c)

Iron

d)

Both A & C

72.

A hormone released by small intestine that inhibits gastric emptying is:

a)

GIP

b)

CCK

c)

Motilin

d)

Gastrin

73.

The major stimulus for pepsinogen is:

a)

Vagus nerve

b)

CCK

c)

Secretin

d)

GIP

74.

Bile pigments are derived from:

a)

Cholesterol

b)

Bilirubin

c)

Amino acids

d)

Fatty acids

75.

Pancreatic secretions have high bicarbonate because they:

a)

Neutralize chyme

b)

Digest proteins

c)

Activate gastrin

d)

Inhibit motility

76.

The hormone that increases during a fatty meal is:

a)

CCK

b)

Secretin

c)

Gastrin

d)

Motilin

77.

Bile acids are conjugated with:

a)

Glycine & taurine

b)

Glucose & fructose

c)

Alanine & valine

d)

Histamine & histidine

78.

A patient with steatorrhea likely has:

a)

Fat malabsorption

b)

Iron deficiency

c)

Lactose intolerance

d)

Acid reflux

79.

Pancreatic enzyme secretion is greatest during:

a)

Intestinal phase

b)

Cephalic phase

c)

Gastric phase

d)

Fasting

80.

Secretin inhibits:

a)

Gastric HCl

b)

Pancreatic bicarbonate

c)

CCK release

d)

Bile production