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Basics of drug regulation

Total questions: 20

Worksheet time: 10mins

Name
Class
Date
1.

The Common Technical Document (CTD) was developed under the initiative of:

a)

WHO

b)

ICH

c)

FDA

d)

EMA

2.

Which CTD module is region-specific and not harmonized?

a)

Module 1

b)

Module 2

c)

Module 3

d)

Module 5

3.

The eCTD primarily differs from CTD because it:

a)

Contains additional modules

b)

Is submitted only in PDF format

c)

Is an electronic, XML-based submission

d)

Is applicable only in the US

4.

Which module of CTD contains the Quality (CMC) information?

a)

Module 2

b)

Module 3

c)

Module 4

d)

Module 5

5.

A New Drug Application (NDA) in the US is submitted under which section of the FD&C Act?

a)

Section 351

b)

Section 505(b)(1)

c)

Section 505(j)

d)

Section 701

6.

An Abbreviated New Drug Application (ANDA) is primarily intended for:

a)

New chemical entities

b)

Biosimilars

c)

Generic drugs

d)

Vaccines

7.

Bioequivalence data in ANDA submission is compared with:

a)

Investigational drug

b)

Reference Listed Drug (RLD)

c)

Placebo

d)

Active Pharmaceutical Ingredient

8.

A Biologics License Application (BLA) in the US is regulated under:

a)

FD&C Act

b)

Drug Price Competition Act

c)

Public Health Service Act

d)

Hatch–Waxman Act

9.

In India, similar biologics are regulated jointly by CDSCO and:

a)

ICMR

b)

DBT

c)

NIPER

d)

AIIMS

10.

The Indian guidelines for Similar Biologics were first issued in:

a)

2008

b)

2009

c)

2012

d)

2018

11.

Which authority is responsible for drug regulation in the JAPAN?

a)

EMA

b)

PMDA

c)

TGA

d)

CDSCO

12.

The regulatory authority of China is:

a)

NMPA

b)

MHLW

c)

JPMA

d)

MHW

13.

Drug regulation in Australia is overseen by:

a)

MHW

b)

NMPA

c)

FDA

d)

TGA

14.

The European Medicines Agency (EMA) evaluates medicines for:

a)

Individual EU countries only

b)

WHO member countries

c)

Non-EU European countries

d)

European Union member states

15.

Centralized marketing authorization in the EU results in approval that is valid in:

a)

One country

b)

Five countries

c)

Selected countries

d)

All EU member states

16.

The Central Drugs Standard Control Organisation (CDSCO) in India functions under:

a)

Ministry of Health & Family Welfare

b)

Ministry of Chemicals & Fertilizers

c)

NITI Aayog

d)

ICMR

17.

Which submission format is mandatory for most regulatory agencies today for lifecycle management?

a)

Paper CTD

b)

NeeS

c)

eCTD

d)

ACTD

18.

What is the primary purpose of a New Drug Application (NDA)?

a)

To report adverse effects

b)

To apply for a patent

c)

To submit post-marketing data

d)

To request approval for a new drug

19.

The International Conference on Harmonisation (ICH) aims to:

a)

Standardize drug pricing

b)

Harmonize regulatory requirements

c)

Develop new drug formulations

d)

Monitor drug safety post-approval

20.

The World Health Organization (WHO) provides guidelines for:

a)

National drug policies

b)

Global health standards

c)

Drug pricing

d)

Pharmaceutical marketing