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HIV Knowledge Quiz

Total questions: 24

Worksheet time: 12mins

Name
Class
Date
1.

HIV belongs to which virus family?

a)

Herpesviridae

b)

Retroviridae

c)

Orthomyxoviridae

d)

Flaviviridae

2.

HIV is classified as

a)

Retrovirus lentivirus

b)

Picornavirus

c)

Reovirus

d)

Parvovirus

3.

HIV genome is

a)

Double-stranded DNA

b)

Single-stranded DNA

c)

Single-stranded RNA (two copies)

d)

Double-stranded RNA

4.

Key enzyme present in HIV for replication is

a)

DNA polymerase

b)

Reverse transcriptase

c)

RNA polymerase

d)

Protease only

5.

HIV envelope glycoprotein responsible for attachment is

a)

gp41

b)

gp120

c)

p24

d)

gp160

6.

HIV primarily infects cells expressing

a)

CD8 receptor

b)

CD4 receptor

c)

CD19 receptor

d)

CD21 receptor

7.

Coreceptor used by HIV for macrophage entry is

a)

CXCR4

b)

CCR5

c)

CD28

d)

CD40

8.

Coreceptor used by HIV for T cell (late) tropism is

a)

CCR5

b)

CXCR4

c)

CD21

d)

CD14

9.

Major mechanism of immunodeficiency in HIV infection is

a)

Loss of B cells

b)

Depletion of CD4 T cells

c)

Complement deficiency

d)

Neutrophil excess

10.

Early clinical stage of HIV infection is

a)

Chronic AIDS stage

b)

Acute retroviral syndrome

c)

Latent infection only

d)

Opportunistic infection only

11.

AIDS is defined by CD4 count less than

a)

1000 cells/µL

b)

750 cells/µL

c)

500 cells/µL

d)

200 cells/µL

12.

Most common mode of HIV transmission worldwide is

a)

Airborne

b)

Feco-oral

c)

Sexual transmission

d)

Vector borne

13.

Vertical transmission of HIV occurs via

a)

Only placenta

b)

Placenta delivery and breastfeeding

c)

Blood transfusion only

d)

Droplet spread

14.

NACO HIV testing strategy uses

a)

Single rapid test only

b)

Two or three tests based on purpose

c)

Only ELISA

d)

Only Western blot

15.

Confirmatory test for HIV infection is

a)

Gram stain

b)

Widal test

c)

Western blot or immunoblot

d)

Catalase test

16.

Viral RNA detection in HIV is done by

a)

ELISA

b)

RT-PCR

c)

Weil-Felix test

d)

Coagulase test

17.

p24 antigen detection is useful for

a)

Late AIDS diagnosis only

b)

Window period detection only

c)

Bacterial infections

d)

Fungal diagnosis

18.

Opportunistic infection in AIDS includes all EXCEPT

a)

Pneumocystis jirovecii pneumonia

b)

Toxoplasmosis

c)

Candidiasis

d)

Typhoid fever

19.

Most common opportunistic fungal infection in AIDS is

a)

Aspergillosis

b)

Candidiasis

c)

Cryptococcosis

d)

Mucormycosis

20.

Weil-Felix test is used in diagnosis of

a)

Typhoid fever

b)

Rickettsial infections

c)

Brucellosis

d)

Leptospirosis

21.

Weil-Felix test is based on

a)

ELISA

b)

Precipitation

c)

Agglutination with Proteus strains

d)

Complement fixation

22.

OXK agglutination in Weil-Felix test suggests

a)

Scrub typhus

b)

Epidemic typhus

c)

Endemic typhus

d)

Rocky Mountain spotted fever

23.

OX19 agglutination in Weil-Felix test is seen in

a)

Epidemic and endemic typhus

b)

Scrub typhus only

c)

Q fever only

d)

Leprosy

24.

Neil-Mooser reaction is associated with

a)

Epidemic typhus

b)

Endemic typhus

c)

Scrub typhus

d)

Brucellosis