Molbio_M2_L3-5_2B

Open Ended

How do you think molecular biology has changed the way forensic investigations are conducted?

Multiple Choice

Why is DNA fingerprinting considered a significant advancement in forensic science?

• It helps identify criminals with high accuracy

• It is used to diagnose infectious diseases

• It can replace all traditional forensic methods

• It is only applicable in paternity testing

Multiple Choice

The photograph shows a laboratory investigator examining samples of DNA in a procedure called PCR, or polymerase chain reaction. Using PCR, the investigator can create thousands or even millions of copies of a fragment of DNA for closer investigation. In which of these situations would PCR be most useful?

• When only a small amount of DNA is available, such as at a crime scene

• When the DNA of identical twins is being mapped

• When the genome of a population is being analyzed for preventable diseases

• When the blood type of a DNA donor is known

Multiple Choice

Which scientist is credited with developing the technique of DNA fingerprinting, and in which decade was it first introduced?

• Alec Jeffreys, 1980s

• James Watson, 1950s

• Francis Crick, 1960s

• Kary Mullis, 1990s

Multiple Select

Which of the following are steps involved in the DNA fingerprinting process?

• DNA Extraction

• Gel Electrophoresis

• Hybridization

• PCR Amplification

Multiple Choice

During the DNA extraction process, which step involves breaking down the cellular structure to release DNA?

• Homogenization

• Purification

• Centrifugation

• Precipitation

Open Ended

Describe the importance of using restriction enzymes in DNA fingerprinting and how they contribute to genetic analysis.

Multiple Choice

Which step in gel electrophoresis is responsible for separating DNA fragments based on their size?

• Loading DNA fragments

• Applying electric current

• Size separation

• Visualization

Open Ended

Explain how the process of blotting and visualization helps in identifying DNA fingerprints.

Multiple Select

Select all statements that correctly describe Short Tandem Repeats (STRs) in DNA profiling.

• STRs are composed of 2-5 base pairs.

• STRs are highly variable among individuals.

• STRs replace minisatellites in DNA profiling.

• STRs are used only in population studies.

Open Ended

Describe the main steps involved in DNA profiling, starting from extraction to detection.

Multiple Choice

Which of the following is an ethical concern associated with DNA fingerprinting?

• Privacy concerns

• Cost of equipment

• Difficulty in sample collection

• Length of DNA fragments

Multiple Choice

Which of the following is a limitation of DNA fingerprinting related to the quality of samples?

• Degraded or contaminated samples can lead to inconclusive results.

• DNA fingerprinting can predict complex genetic traits.

• Negative results always imply innocence.

• DNA fingerprinting is never used in crime investigations.

Open Ended

How do advancements in technology and integration with AI contribute to future trends in DNA technologies?

Multiple Select

Which of the following are key steps in the DNA fingerprinting process?

• Extraction

• Cutting

• Separation

• Visualization

Open Ended

Explain how gene mapping can be applied in personalized medicine and gene therapy.

Multiple Choice

What is the primary purpose of gene mapping?

• Mapping the locations of genes on chromosomes

• Identifying protein structures

• Analyzing environmental DNA

• Detecting viral infections

Multiple Choice

Which scientist is credited with describing genetic linkage in fruit flies, laying the foundation for linkage mapping techniques?

• Gregor Mendel

• James Watson

• Thomas Hunt Morgan

• Rosalind Franklin

Multiple Select

Select all concepts that are directly related to gene mapping.

• Gene locus

• Genetic marker

• Recombination

• Protein synthesis

Open Ended

Explain the significance of recombination in gene mapping and how it contributes to locating genes on chromosomes.

Multiple Choice

Which of the following steps is NOT typically involved in creating genetic maps?

• Collecting DNA samples

• Identifying genetic markers

• Analyzing protein folding

• Analyzing recombination patterns

Multiple Choice

Which of the following best explains the technique of DNA fingerprinting?

• It identifies individuals based on unique patterns in their DNA.

• It is used to diagnose infectious diseases.

• It maps the entire human genome.

• It determines the age of a biological sample.

Open Ended

How does molecular biology contribute to forensic medicine?