Glycolysis II

What is the function of kinase?

• Kinase is an enzyme that phosphorylates its substrates

• Kinases are enzymes catalyzes dephosphorylation

• Kinases are always activated by insulin

How is glucokinase different from hexokinase?

• Glucokinase phosphorylates only glucose while hexokinase phosphorylates other sugars

• Glucokinase has a low affinity for glucose and a high Vmax compared to hexokinase

• Glucokinase is activated by G6P and inhibited by F6P

How does glucagon affect the levels of PFK2?

• Glucagon increases glycolysis and PFK2 activity

• Glucagon inhibits the kinase activity of PFK2 and activates the phosphatase activity

• Glucagon increases the activity of PFK2

• Glucagon has no effect on PFK2

What is substrate level phosphorylation?

• When ATP is generated in form of NADH

• When ATP is directly generated as a/one product in a reaction

• When a protein phosphorylates a substrate

How many ATP are generated by breakdown of one glucose molecule to pyruvate under aerobic circumstances?

• 8 ATP

• 6 ATP

• 2 ATP

• 4 ATP

Name the enzymes in the rate limiting steps of glycolysis.

• Carbonic anhydrase

  Lactate dehydrogenase

  PFK-1

• Pyruvate kinase

  PFK-1

  Hexokinase

• a-ketoglutarate

  Catalase

  Glucokinase

Which step of glycolysis is connected with glycogen synthesis?

• Pyrvate

• Glucose 6 phosphate

• Glucose

• Fructose 6 phosphate