BIO442 Presentation

Occurs when a cell's demand for oxygen exceeds its oxygen supply

• Hyperoxia

• Homeostasis

• Hypoxia

• Apoptosis

Embryological development of blood vessels from endothelial stem cells

• Angiogenesis

• Vasculogenesis

• Neoangiogenesis

• Proliferation

Which was NOT a factor discussed to determine the particular oxygen level of a tumor in the body?

• Type of tissue or organ

• Size of the tumor

• Initial oxygen level of the tissue

• Color of the tumor

What is autophagy?

• Self-signalling a cell to replicate

• Recycling and degrading old and damaged cells

• Causing a cell's ROS levels to increase

• Angiogenesis in cancer cells

What does HIF stand for?

• hyperoxia-inducible factors

• hypoxia-influenced growth factors

• hypoxia-independent factor

• hypoxia-inducible factors

Which of the following can influence and regulate HIF activity?

• Radiation

• Chemotherapy

• Surgery

• Antibiotics

Which compound causes vasodilation?

• CO2

• NO

• O2

• YES

Which is NOT an effect of the HIF pathway?

• Decreased mitochondrial respiration

• Increased glucose uptake

• Decreased glycolysis rate

• Increased blood flow

What does MMP stand for?

• membrane migration proteinase

• myeloid metastasis protein

• matrix metallo proteinase

• I have no idea

Which is not part of the vicious cycle discussed?

• Angiogenesis

• Metastasis

• Hypoxia

• Tumor proliferation