Bolognia Quiz

Which antibody is most specific for this condition?

• ANA

• SCL-70

• Topoisomerase II

• Endothelial Cell

Of the following autoantibodies, which is associated with a poor prognosis of interstitial lung disease?

• Anti-Centromere

• Anti-RNA Polymerase III

• Anti-U3 RNP

• Anti-Topoisomerase I

Patient arrives to dermatology clinic reporting new hypopigmentation over his elbow. The likely diagnosis is:

• Vitiligo

• Corticosteroid-Induced Hypopigmentation

• Hypopigmented Mycosis Fungoides

• Morphea

• Lichen Sclerosis

Which of the following is a risk factor for the development of this condition?

• Penicillamine

• Radiation

• Lymphedema

• PUVA

• MTX

What is the best diagnosis?

• Lichen sclerosus

• Lichen planus

• Lichen striatus

• Lichen amyloid

• Lichen aureus

Which diagnosis is the finding pictured associated with?

• SSc

• LP

• MMP

• DM

• Eosinophilic Fasiitis

Patient wants to know why her leg looks like this. What is the best step to confirm the diagnosis?

• Serum Immunoglobulins

• MRI Right Lower Extremity

• Incisional Biopsy

• CBC for Eosinophilia

A 65-year-old man presents with skin lesions that he has recently noticed on his legs and arms. PMH ESRD on hemodialysis. He recently he has had an MRI with contrast for the evaluation of an abdominal mass. On examination, vitals WNL. Examination of his legs reveals thickened and hyperpigmented skin with woody consistency. Which of the following is NOT a complication of the underlying condition?

• Pulmonary Hypertension

• Cardiomyopathy

• Skeletal Muscle Weakness

• Flexion Contractures

• Hypertension

What is the #1 cause of death in patients with this condition?

• Pneumonia

• Renal Crisis

• Congestive Heart Failure

• Intracranial Hemorrhage

You're consulted on a 7 year old female with nightly fevers of 40C and this rash which comes and goes. Select which labs you would expect to be elevated in this patient.

• Ferritin

• IL-1

• ESR

• CRP